Uses inverse probability weighting methods to estimate treatment effect under marginal structure model for the cause-specific hazard of competing risk events. Estimates also the cumulative incidence function (i.e. risk) of the potential outcomes, and provides inference on risk difference and risk ratio. Reference: Kalbfleisch & Prentice (2002)<doi:10.1002/9781118032985>; Hernan et al (2001)<doi:10.1198/016214501753168154>.

Run computer experiments using the adaptive composite grid algorithm with a Gaussian process model. The algorithm works best when running an experiment that can evaluate thousands of points from a deterministic computer simulation. This package is an implementation of a forthcoming paper by Plumlee, Erickson, Ankenman, et al. For a preprint of the paper, contact the maintainer of this package.

Utilize the shiny interface to parameterize a Visual Predictive Check (VPC), including selecting from different binning or binless methods and performing stratification, censoring, and prediction correction. Generate the underlying tidyvpc and ggplot2 code directly from the user interface and download R or Rmd scripts to reproduce the VPCs in R.

Compare color palettes with simulations of color vision deficiencies - deuteranopia, protanopia, and tritanopia. It includes calculation of distances between colors, and creating summaries of differences between a color palette and simulations of color vision deficiencies. This work was inspired by the blog post at <https://www.datawrapper.de/blog/colorblind-check>.

Computes confidence intervals for the positive predictive value (PPV) and negative predictive value (NPV) based on varied scenarios. In situations where the proportion of diseased subjects does not correspond to the disease prevalence (e.g. case-control studies), this package provides two types of solutions: 1) five methods for estimating confidence intervals for PPV and NPV via ratio of two binomial proportions including Gart & Nam (1988), Walter (1975), MOVER-J (Laud, 2017), Fieller (1954), and Bootstrap (Efron, 1979); 2) three direct methods that compute the confidence intervals including Pepe (2003), Zhou (2007), and Delta. In prospective studies where the proportion of diseased subjects is an unbiased estimate of the disease prevalence, this package provides several methods for calculating the confidence intervals for PPV and NPV including Clopper-Pearson, Wald, Wilson, Agresti-Coull, and Beta. See the Details and References sections in the corresponding functions.

Non-parametric tests (Wilcoxon rank sum test and Wilcoxon signed rank test) for clustered data documented in Jiang et. al (2020) <doi:10.18637/jss.v096.i06>.

This package provides functions and data files to help CE Public-Use Microdata (PUMD) users calculate annual estimated expenditure means, standard errors, and quantiles according to the methods used by the CE with PUMD. For more information on the CE please visit <https://www.bls.gov/cex>. For further reading on CE estimate calculations please see the CE Calculation section of the U.S. Bureau of Labor Statistics (BLS) Handbook of Methods at <https://www.bls.gov/opub/hom/cex/calculation.htm>. For further information about CE PUMD please visit <https://www.bls.gov/cex/pumd.htm>.

Merging data from multiple sources is a relevant approach for comprehensively evaluating complex systems. However, the inherent problems encountered when analyzing single tables are amplified with the generation of multi-block datasets, and finding the relationships between data layers of increasing complexity constitutes a challenging task. For that purpose, a generic methodology is proposed by combining the strength of established data analysis strategies, i.e. multi-block approaches and the Orthogonal Partial Least Squares (OPLS) framework to provide an efficient tool for the fusion of data obtained from multiple sources. The package enables quick and efficient implementation of the consensus OPLS model for any horizontal multi-block data structures (observation-based matching). Moreover, it offers an interesting range of metrics and graphics to help to determine the optimal number of components and check the validity of the model through permutation tests. Interpretation tools include score and loading plots, Variable Importance in Projection (VIP), functionality predict for SHAP computing, and performance coefficients such as R2, Q2, and DQ2 coefficients. J. Boccard and D.N. Rutledge (2013) <doi:10.1016/j.aca.2013.01.022>.

It computes full conformal, split conformal and multi split conformal prediction regions when the response has functional nature. Moreover, the package also contain a plot function to visualize the output of the split conformal. To guarantee consistency, the package structure mimics the univariate conformalInference package of professor Ryan Tibshirani. The main references for the code are: Diquigiovanni, Fontana, and Vantini (2021) <arXiv:2102.06746>, Diquigiovanni, Fontana, and Vantini (2021) <arXiv:2106.01792>, Solari, and Djordjilovic (2021) <arXiv:2103.00627>.

This package implements the Cross-contribution Compensating Multiple standard Normalization (CCMN) method described in Redestig et al. (2009) Analytical Chemistry <doi:10.1021/ac901143w> and other normalization algorithms.

This package provides a collection of functions to generate a large variety of structures in high dimensions. These data structures are useful for testing, validating, and improving algorithms used in dimensionality reduction, clustering, machine learning, and visualization.

Hierarchical and partitioning algorithms to cluster blocks of variables. The partitioning algorithm includes an option called noise cluster to set aside atypical blocks of variables. Different thresholds per cluster can be sets. The CLUSTATIS method (for quantitative blocks) (Llobell, Cariou, Vigneau, Labenne & Qannari (2020) <doi:10.1016/j.foodqual.2018.05.013>, Llobell, Vigneau & Qannari (2019) <doi:10.1016/j.foodqual.2019.02.017>) and the CLUSCATA method (for Check-All-That-Apply data) (Llobell, Cariou, Vigneau, Labenne & Qannari (2019) <doi:10.1016/j.foodqual.2018.09.006>, Llobell, Giacalone, Labenne & Qannari (2019) <doi:10.1016/j.foodqual.2019.05.017>) are the core of this package. The CATATIS methods allows to compute some indices and tests to control the quality of CATA data. Multivariate analysis and clustering of subjects for quantitative multiblock data, CATA, RATA, Free Sorting and JAR experiments are available. Clustering of rows in multi-block context (notably with ClusMB strategy) is also included.

This package provides functions for constructing and evaluating CUSUM charts and RA-CUSUM charts with focus on false signal probability.

We propose a method to estimate the probability of an undetected case of COVID-19 in a defined setting, when a given number of people have been exposed, with a given pretest probability of having COVID-19 as a result of that exposure. Since we are interested in undetected COVID-19, we assume no person has developed symptoms (which would warrant further investigation) and that everyone was tested on a given day, and all tested negative.

Access chemical, hazard, bioactivity, and exposure data from the Computational Toxicology and Exposure ('CTX') APIs <https://www.epa.gov/comptox-tools/computational-toxicology-and-exposure-apis>. ctxR was developed to streamline the process of accessing the information available through the CTX APIs without requiring prior knowledge of how to use APIs. Most data is also available on the CompTox Chemical Dashboard ('CCD') <https://comptox.epa.gov/dashboard/> and other resources found at the EPA Computational Toxicology and Exposure Online Resources <https://www.epa.gov/comptox-tools>.

Create an addin in Rstudio to do fill-in-the-middle (FIM) and chat with latest Mistral AI models for coding, Codestral and Codestral Mamba'. For more details about Mistral AI API': <https://docs.mistral.ai/getting-started/quickstart/> and <https://docs.mistral.ai/api/>. For more details about Codestral model: <https://mistral.ai/news/codestral>; about Codestral Mamba': <https://mistral.ai/news/codestral-mamba>.

This package implements the Bayesian calibration model described in Pratola and Chkrebtii (2018) <DOI:10.5705/ss.202016.0403> for stochastic and deterministic simulators. Additive and multiplicative discrepancy models are currently supported. See <http://www.matthewpratola.com/software> for more information and examples.

This package implements Monte Carlo conditional inference for the parameters of a linear nonnormal regression model.

Convert BCD (raw bytes) to decimal numbers and vice versa. BCD format is used to preserve decimals exactly, as opposed to the binary rounding errors inherent in "numeric" or "floating-point" formats.

This package performs forward and backwards stepwise regression for the Proportional subdistribution hazards model in competing risks (Fine & Gray 1999). Procedure uses AIC, BIC and BICcr as selection criteria. BICcr has a penalty of k = log(n*), where n* is the number of primary events.

The CalMaTe method calibrates preprocessed allele-specific copy number estimates (ASCNs) from DNA microarrays by controlling for single-nucleotide polymorphism-specific allelic crosstalk. The resulting ASCNs are on average more accurate, which increases the power of segmentation methods for detecting changes between copy number states in tumor studies including copy neutral loss of heterozygosity. CalMaTe applies to any ASCNs regardless of preprocessing method and microarray technology, e.g. Affymetrix and Illumina.

This package provides a helpful R6 class and methods for interacting with the Posit Connect Server API along with some meaningful utility functions for regular tasks. API documentation varies by Posit Connect installation and version, but the latest documentation is also hosted publicly at <https://docs.posit.co/connect/api/>.

Conditional graphical lasso estimator is an extension of the graphical lasso proposed to estimate the conditional dependence structure of a set of p response variables given q predictors. This package provides suitable extensions developed to study datasets with censored and/or missing values. Standard conditional graphical lasso is available as a special case. Furthermore, the package provides an integrated set of core routines for visualization, analysis, and simulation of datasets with censored and/or missing values drawn from a Gaussian graphical model. Details about the implemented models can be found in Augugliaro et al. (2023) <doi: 10.18637/jss.v105.i01>, Augugliaro et al. (2020b) <doi: 10.1007/s11222-020-09945-7>, Augugliaro et al. (2020a) <doi: 10.1093/biostatistics/kxy043>, Yin et al. (2001) <doi: 10.1214/11-AOAS494> and Stadler et al. (2012) <doi: 10.1007/s11222-010-9219-7>.

Modeling periodic mortality (or other time-to event) processes from right-censored data. Given observations of a process with a known period (e.g. 365 days, 24 hours), functions determine the number, intensity, timing, and duration of peaks of periods of elevated hazard within a period. The underlying model is a mixed wrapped Cauchy function fitted using maximum likelihoods (details in Gurarie et al. (2020) <doi:10.1111/2041-210X.13305>). The development of these tools was motivated by the strongly seasonal mortality patterns observed in many wild animal populations. Thus, the respective periods of higher mortality can be identified as "mortality seasons".