This package contains a number of comparative "phylogenetic" methods, mostly focusing on analysing diversification and character evolution. Contains implementations of "BiSSE" (Binary State Speciation and Extinction) and its unresolved tree extensions, "MuSSE" (Multiple State Speciation and Extinction), "QuaSSE", "GeoSSE", and "BiSSE-ness" Other included methods include Markov models of discrete and continuous trait evolution and constant rate speciation and extinction.

The clusterCrit package provides an implementation of the following indices: Czekanowski-Dice, Folkes-Mallows, Hubert Γ, Jaccard, McNemar, Kulczynski, Phi, Rand, Rogers-Tanimoto, Russel-Rao or Sokal-Sneath. ClusterCrit defines several functions which compute internal quality indices or external comparison indices. The partitions are specified as an integer vector giving the index of the cluster each observation belongs to.

This package provides routines for the analysis of indirectly measured haplotypes. The statistical methods assume that all subjects are unrelated and that haplotypes are ambiguous (due to unknown linkage phase of the genetic markers). The main functions are: haplo.em(), haplo.glm(), haplo.score(), and haplo.power(); all of which have detailed examples in the vignette.

This package provides grid grobs that fill in a user-defined area with various patterns. It includes enhanced versions of the geometric and image-based patterns originally contained in the ggpattern package as well as original pch, polygon_tiling, regular_polygon, rose, text, wave, and weave patterns plus support for custom user-defined patterns.

AgiMicroRna provides useful functionality for the processing, quality assessment and differential expression analysis of Agilent microRNA array data. The package uses a limma-like structure to generate the processed data in order to make statistical inferences about differential expression using the linear model features implemented in limma. Standard Bioconductor objects are used so that other packages could be used as well.

Multivariate data sets often differ in several factors or derived statistical parameters, which have to be selected for a valid interpretation. Basing this selection on traditional statistical limits leads occasionally to the perception of losing information from a data set. This package provides tools to calculate these limits on the basis of the mathematical properties of the distribution of the analyzed items.

This package provides an htmlwidgets interface to billboard.js, a re-usable easy interface JavaScript chart library, based on D3 v4+. Chart types include line charts, scatterplots, bar/lollipop charts, histogram/density plots, pie/donut charts and gauge charts. All charts are interactive, and a proxy method is implemented to smoothly update a chart without rendering it again in shiny apps.

NanoMethViz is a toolkit for visualising methylation data from Oxford Nanopore sequencing. It can be used to explore methylation patterns from reads derived from Oxford Nanopore direct DNA sequencing with methylation called by callers including nanopolish, f5c and megalodon. The plots in this package allow the visualisation of methylation profiles aggregated over experimental groups and across classes of genomic features.

The scRNAseqApp is a Shiny app package designed for interactive visualization of single-cell data. It is an enhanced version derived from the ShinyCell, repackaged to accommodate multiple datasets. The app enables users to visualize data containing various types of information simultaneously, facilitating comprehensive analysis. Additionally, it includes a user management system to regulate database accessibility for different users.

BBCAnalyzer is a package for visualizing the relative or absolute number of bases, deletions and insertions at defined positions in sequence alignment data available as bam files in comparison to the reference bases. Markers for the relative base frequencies, the mean quality of the detected bases, known mutations or polymorphisms and variants called in the data may additionally be included in the plots.

ZToolkit (Ztk) is a cross-platform GUI toolkit heavily inspired by GTK. It handles events and low level drawing on behalf of the user and provides a high-level API for managing the UI and custom widgets. ZToolkit is written in C and was created to be used for building audio plugin UIs, where the dependencies often need to be kept to a minimum.

This package provides a unified parallelization framework for multiple backends. This package is designed for internal package and interactive usage. The main operation is parallel mapping over lists. It supports local, multicore, mpi and BatchJobs mode. It allows tagging of the parallel operation with a level name that can be later selected by the user to switch on parallel execution for exactly this operation.

This package provides visualization of the results from the multiple (i.e. pairwise) comparison tests such as pairwise.t.test, pairwise.prop.test or pairwise.wilcox.test. The groups being compared are visualized as nodes in Hasse diagram. Such approach enables very clear and vivid depiction of which group is significantly greater than which others, especially if comparing a large number of groups.

This package parses a fitted R model object, and returns a formula in Tidy Eval code that calculates the predictions. It works with several database backends because it leverages dplyr and dbplyr for the final SQL translation of the algorithm. It currently supports lm(), glm(), randomForest(), ranger(), earth(), xgb.Booster.complete(), cubist(), and ctree() models.

This package helps you create plots of p-values using single SNP and/or haplotype data. Main features of the package include options to display a linkage disequilibrium (LD) plot and the ability to plot multiple datasets simultaneously. Plots can be created using global and/or individual haplotype p-values along with single SNP p-values. Images are created as either PDF/EPS files.

This package adds distinctive yet unobtrusive geometric patterns where solid color fills are normally used. Patterned figures look just as professional when viewed by colorblind readers or when printed in black and white. The dozen included patterns can be customized in terms of scale, rotation, color, fill, line type, and line width. It is compatible with the ggplot2 package as well as grid graphics.

This package provides an XML-RPC client for Emacs capable of both synchronous and asynchronous method calls using the url package's async retrieval functionality. xml-rpc.el represents XML-RPC datatypes as Lisp values, automatically converting to and from the XML datastructures as needed, both for method parameters and return values, making using XML-RPC methods fairly transparent to the Lisp code.

This package defines low-level functions for mass spectrometry data and is independent of any high-level data structures. These functions include mass spectra processing functions (noise estimation, smoothing, binning), quantitative aggregation functions (median polish, robust summarisation, etc.), missing data imputation, data normalisation (quantiles, vsn, etc.) as well as misc helper functions, that are used across high-level data structure within the R for Mass Spectrometry packages.

This package generates graphics with embedded details from statistical tests. Statistical tests included in the plots themselves. It provides an easier syntax to generate information-rich plots for statistical analysis of continuous or categorical data. Currently, it supports the most common types of statistical approaches and tests: parametric, nonparametric, robust, and Bayesian versions of t-test/ANOVA, correlation analyses, contingency table analysis, meta-analysis, and regression analyses.

MerfishData is an ExperimentHub package that serves publicly available datasets obtained with Multiplexed Error-Robust Fluorescence in situ Hybridization (MERFISH). MERFISH is a massively multiplexed single-molecule imaging technology capable of simultaneously measuring the copy number and spatial distribution of hundreds to tens of thousands of RNA species in individual cells. The scope of the package is to provide MERFISH data for benchmarking and analysis.

# NetActivity enables to compute gene set scores from previously trained sparsely-connected autoencoders. The package contains a function to prepare the data (`prepareSummarizedExperiment`) and a function to compute the gene set scores (`computeGeneSetScores`). The package `NetActivityData` contains different pre-trained models to be directly applied to the data. Alternatively, the users might use the package to compute gene set scores using custom models.

Rank results by confident effect sizes, while maintaining False Discovery Rate and False Coverage-statement Rate control. Topconfects is an alternative presentation of TREAT results with improved usability, eliminating p-values and instead providing confidence bounds. The main application is differential gene expression analysis, providing genes ranked in order of confident log2 fold change, but it can be applied to any collection of effect sizes with associated standard errors.

Asio is a cross-platform C++ library for network and low-level I/O programming that provides developers with a consistent asynchronous model using a modern C++ approach. It is also included in Boost but requires linking when used with Boost. Standalone it can be used header-only (provided a recent compiler). Asio is written and maintained by Christopher M. Kohlhoff, and released under the Boost Software License', Version 1.0.

This R package helps the user identify k-mers (e.g. di- or tri-nucleotides) present periodically in a set of genomic loci (typically regulatory elements). The functions of this package provide a straightforward approach to find periodic occurrences of k-mers in DNA sequences, such as regulatory elements. It is not aimed at identifying motifs separated by a conserved distance; for this type of analysis, please visit MEME website.