Generate mean and median weighted or unweighted spatial centers. Functions are analogous to their identically named counterparts within ArcGIS Pro'. Median center methodology based off of Kuhn and Kuenne (1962) <doi:10.1111/j.1467-9787.1962.tb00902.x>.

Tables summarizing clinical trial results are often complex and require detailed tailoring prior to submission to a health authority. The crane package supplements the functionality of the gtsummary package for creating these often highly bespoke tables in the pharmaceutical industry.

By overloading the R help() function, this package allows users to use "docstring" style comments within their own defined functions. The package also provides additional functions to mimic the R basic example() function and the prototyping of packages.

This package implements the new algorithm for fast computation of M-scatter matrices using a partial Newton-Raphson procedure for several estimators. The algorithm is described in Duembgen, Nordhausen and Schuhmacher (2016) <doi:10.1016/j.jmva.2015.11.009>.

Calculation of Evapotranspiration by FAO Penman-Monteith equation based on Allen, R. G., Pereira, L. S., Raes, D., Smith, M. (1998, ISBN:92-5-104219-5) "Crop evapotranspiration - Guidelines for computing crop water requirements - FAO Irrigation and drainage paper 56".

Sets up and executes a HiSSE model (Hidden State Speciation and Extinction) on a phylogeny and character sets to test for hidden shifts in trait dependent rates of diversification. Beaulieu and O'Meara (2016) <doi:10.1093/sysbio/syw022>.

Simplifies the whole process of creating stacked tilted maps, that are often used in scientific publications to show different environmental layers for a geographical region. Tilting maps and layering them allows to easily draw visual correlations between these environmental layers.

Mixture model with overlapping clusters for binary actor-event data. Parameters are estimated in a Bayesian framework. Model and inference are described in Ranciati, Vinciotti, Wit (2017) Modelling actor-event network data via a mixture model under overlapping clusters. Submitted.

Bending non-positive-definite (symmetric) matrices to positive-definite, using weighted and unweighted methods. Jorjani, H., et al. (2003) <doi:10.3168/jds.S0022-0302(03)73646-7>. Schaeffer, L. R. (2014) <http://animalbiosciences.uoguelph.ca/~lrs/ELARES/PDforce.pdf>.

Determines single or multiple modes (most frequent values). Checks if missing values make this impossible, and returns NA in this case. Dependency-free source code. See Franzese and Iuliano (2019) <doi:10.1016/B978-0-12-809633-8.20354-3>.

Calculates a cumulative summation nonparametric extended median test based on the work of Brown & Schaffer (2020) <DOI:10.1080/03610926.2020.1738492>. It then generates a control chart to assess processes and determine if any streams are out of control.

Grows a qualitative interaction tree. Quint is a tool for subgroup analysis, suitable for data from a two-arm randomized controlled trial. More information in Dusseldorp, E., Doove, L., & Van Mechelen, I. (2016) <doi:10.3758/s13428-015-0594-z>.

Code and data for modelling and simulation of stochastic kinetic biochemical network models. It contains the code and data associated with the second and third editions of the book Stochastic Modelling for Systems Biology, published by Chapman & Hall/CRC Press.

This package provides a general, tidyverse'-friendly framework for simulation studies, design analysis, and power analysis. Specify data generation, define varying parameters, generate data, fit models, and tidy model results in a single pipeline, without needing loops or custom functions.

This package provides a covariance estimator for multivariate normal data that is sparse and positive definite. Implements the majorize-minimize algorithm described in Bien, J., and Tibshirani, R. (2011), "Sparse Estimation of a Covariance Matrix," Biometrika. 98(4). 807--820.

This package provides a type system for R. It supports setting variable types in a script or the body of a function, so variables can't be assigned illegal values. Moreover it supports setting argument and return types for functions.

This package provides various commonly-used response time trimming methods, including the recursive / moving-criterion methods reported by Van Selst and Jolicoeur (1994). By passing trimming functions raw data files, the package will return trimmed data ready for inferential testing.

This package provides a tool to obtain tumor growth rates from clinical trial patient data. Output includes individual and summary data for tumor growth rate estimates as well as optional plots of the observed and predicted tumor quantity over time.

Two Phase I designs are implemented in the package: the classical 3+3 and the Continual Reassessment Method (<doi:10.2307/2531628>). Simulations tools are also available to estimate the operating characteristics of the methods with several user-dependent options.

Compared with the similar graph embedding method such as Laplacian Eigenmaps, Vicus can exploit more local structures of graph data. For the details of the methods, see the reference section of GitHub README.md <https://github.com/rikenbit/Vicus>.

Makes available code necessary to reproduce figures and tables in papers on the WaveD method for wavelet deconvolution of noisy signals as presented in The WaveD Transform in R, Journal of Statistical Software Volume 21, No. 3, 2007.

Identification of diferentially methylated regions (DMRs) in predefined regions (promoters, CpG islands...) from the human genome using Illumina's 450K or EPIC microarray data. Provides methods to rank CpG probes based on linear models and includes plotting functions.

The purpose of ncGTW is to help XCMS for LC-MS data alignment. Currently, ncGTW can detect the misaligned feature groups by XCMS, and the user can choose to realign these feature groups by ncGTW or not.

This package is designed to uncover the intrinsic cell progression path from single-cell RNA-seq data. It incorporates data pre-processing, preliminary PCA gene selection, preliminary cell ordering, feature selection, refined cell ordering, and post-analysis interpretation and visualization.