This package provides a method to explore the treatment-covariate interactions in survival or generalized linear model (GLM) for continuous, binomial and count data arising from two or more treatment arms of a clinical trial. A permutation distribution approach to inference is implemented, based on permuting the covariate values within each treatment group.

Allows the user to connect with the World Spider Catalogue (WSC; <https://wsc.nmbe.ch/>) and the World Spider Trait (WST; <https://spidertraits.sci.muni.cz/>) databases. Also performs several basic functions such as checking names validity, retrieving coordinate data from the Global Biodiversity Information Facility (GBIF; <https://www.gbif.org/>), and mapping.

This package provides routines to check identifiability or non-identifiability of linear structural equation models as described in Drton, Foygel, and Sullivant (2011) <doi:10.1214/10-AOS859>, Foygel, Draisma, and Drton (2012) <doi:10.1214/12-AOS1012>, and other works. The routines are based on the graphical representation of structural equation models.

Likelihood ratio and maximum likelihood statistics are provided that can be used as alternatives to p-values Colquhoun (2017) <doi:10.1098/rsos.171085>. Arguments can be either p-values or t-statistics. together with degrees of freedom. For the function tTOlr', the argument twoSided has the default twoSided = TRUE'.

Obtain United States map data frames of varying region types (e.g. county, state). The map data frames include Alaska and Hawaii conveniently placed to the bottom left, as they appear in most maps of the US. Convenience functions for plotting choropleths, visualizing spatial data, and working with FIPS codes are also provided.

Supplies permutation-test alternatives to traditional hypothesis-test procedures such as two-sample tests for means, medians, and standard deviations; correlation tests; tests for homogeneity and independence; and more. Suitable for general audiences, including individual and group users, introductory statistics courses, and more advanced statistics courses that desire an introduction to permutation tests.

Nonparametric estimation of discount functions and yield curves from transaction data of coupon paying bonds. Koo, B., La Vecchia, D., & Linton, O. B. (2021) <doi:10.1016/j.jeconom.2020.04.014> describe an application of this package using the Center for Research in Security Prices (CRSP) Bond Data and document its implementation.

performing all the steps of gene expression meta-analysis considering the possible existence of missing genes. It provides the necessary functions to be able to perform the different methods of gene expression meta-analysis. In addition, it contains functions to apply quality controls, download GEO datasets and show graphical representations of the results.

This package provides a package for gene set analysis based on the variability of expressions as well as a method to detect Alternative Splicing Events . It implements DIfferential RAnk Conservation (DIRAC) and gene set Expression Variation Analysis (EVA) methods. For detecting Differentially Spliced genes, it provides an implementation of the Spliced-EVA (SEVA).

This package provides functions for reading, writing, plotting, analysing, and manipulating allelic and haplotypic data, including from VCF files, and for the analysis of population nucleotide sequences and micro-satellites including coalescent analyses, linkage disequilibrium, population structure (Fst, Amova) and equilibrium (HWE), haplotype networks, minimum spanning tree and network, and median-joining networks.

Iterative least cost path and minimum spanning tree methods for projecting forest road networks. The methods connect a set of target points to an existing road network using igraph <https://igraph.org> to identify least cost routes. The cost of constructing a road segment between adjacent pixels is determined by a user supplied weight raster and a weight function; options include the average of adjacent weight raster values, and a function of the elevation differences between adjacent cells that penalizes steep grades. These road network projection methods are intended for integration into R workflows and modelling frameworks used for forecasting forest change, and can be applied over multiple time-steps without rebuilding a graph at each time-step.

The base functions for set operations in R can be used for only two sets. This package RVenn provides functions for dealing with multiple sets. It uses purr to find the union, intersection and difference of three or more sets. This package also provides functions for pairwise set operations among several sets. Further, based on ggplot2 and ggforce, a Venn diagram can be drawn for two or three sets. For bigger data sets, a clustered heatmap showing the presence or absence of the elements of the sets can be drawn based on the pheatmap package. Finally, enrichment test can be applied to two sets whether an overlap is statistically significant or not.

Regularised discriminant analysis functions. The classical regularised discriminant analysis proposed by Friedman in 1989, including cross-validation, of which the linear and quadratic discriminant analyses are special cases. Further, the regularised maximum likelihood linear discriminant analysis, including cross-validation. References: Friedman J.H. (1989): "Regularized Discriminant Analysis". Journal of the American Statistical Association 84(405): 165--175. <doi:10.2307/2289860>. Friedman J., Hastie T. and Tibshirani R. (2009). "The elements of statistical learning", 2nd edition. Springer, Berlin. <doi:10.1007/978-0-387-84858-7>. Tsagris M., Preston S. and Wood A.T.A. (2016). "Improved classification for compositional data using the alpha-transformation". Journal of Classification, 33(2): 243--261. <doi:10.1007/s00357-016-9207-5>.

Simulation tool to estimate the rate of success that surveys possessing user-specific characteristics have in identifying archaeological sites (or any groups of clouds of objects), given specific parameters of survey area, survey methods, and site properties. The survey approach used is largely based on the work of Kintigh (1988) <doi:10.2307/281113>.

Scripting of structural equation models via lavaan for Dyadic Data Analysis, and helper functions for supplemental calculations, tabling, and model visualization. Current models supported include Dyadic Confirmatory Factor Analysis, the Actorâ Partner Interdependence Model (observed and latent), the Common Fate Model (observed and latent), Mutual Influence Model (latent), and the Bifactor Dyadic Model (latent).

Produce maximum likelihood estimates of common accuracy statistics for multiple measurement methods when a gold standard is not available. An R implementation of the expectation maximization algorithms described in Zhou et al. (2011) <doi:10.1002/9780470906514> with additional functions for creating simulated data and visualizing results. Supports binary, ordinal, and continuous measurement methods.

Create fake datasets that can be used for prototyping and teaching. This package provides a set of functions to generate fake data for a variety of data types, such as dates, addresses, and names. It can be used for prototyping (notably in shiny') or as a tool to teach data manipulation and data visualization.

We propose the inverse probability-of-censoring weighted (IPCW) Kendall's tau to measure the association of the survival trait with biomarkers and Kendall's partial correlation to reflect the relationship of the survival trait with interaction variable conditional on main effects, as described in Wang and Chen (2020) <doi:10.1093/bioinformatics/btaa017>.

This package provides a GUI interface for automating data extraction from multiple images containing scatter and bar plots, semi-automated tools to tinker with extraction attempts, and a fully-loaded point-and-click manual extractor with image zoom, calibrator, and classifier. Also provides detailed and R-independent extraction reports as fully-embedded .html records.

This package provides a set of functions to compute the Hodrick-Prescott (HP) filter with automatically selected jumps. The original HP filter extracts a smooth trend from a time series, and our version allows for a small number of automatically identified jumps. See Maranzano and Pelagatti (2024) <doi:10.2139/ssrn.4896170> for details.

This package implements the LS-PLS (least squares - partial least squares) method described in for instance Jørgensen, K., Segtnan, V. H., Thyholt, K., Næs, T. (2004) "A Comparison of Methods for Analysing Regression Models with Both Spectral and Designed Variables" Journal of Chemometrics, 18(10), 451--464, <doi:10.1002/cem.890>.

This package provides a variety of models to analyze latent variables based on Bayesian learning: the partially CFA (Chen, Guo, Zhang, & Pan, 2020) <DOI: 10.1037/met0000293>; generalized PCFA; partially confirmatory IRM (Chen, 2020) <DOI: 10.1007/s11336-020-09724-3>; Bayesian regularized EFA <DOI: 10.1080/10705511.2020.1854763>; Fully and partially EFA.

This package provides a generalization of principal component analysis for integrative analysis. The method finds principal components that describe single matrices or that are common to several matrices. The solutions are sparse. Rank of solutions is automatically selected using cross validation. The method is described in Kallus et al. (2019) <arXiv:1911.04927>.

Classify missing data as missing completely at random (MCAR), missing at random (MAR), or missing not at random (MNAR). This step is required before handling missing data (e.g. mean imputation) so that bias is not introduced. See Little (1988) <doi:10.1080/01621459.1988.10478722> for the statistical rationale for the methods used.