Piecewise linear segmentation of ordered data by a dynamic programming algorithm. The algorithm was developed for time series data, e.g. growth curves, and for genome-wide read-count data from next generation sequencing, but is broadly applicable. Generic implementations of dynamic programming routines allow to scan for optimal segmentation parameters and test custom segmentation criteria ("scoring functions").

Create list comprehensions (and other types of comprehension) similar to those in python', haskell', and other languages. List comprehension in R converts a regular for() loop into a vectorized lapply() function. Support for looping with multiple variables, parallelization, and across non-standard objects included. Package also contains a variety of functions to help with list comprehension.

This package provides functions to implement the Flexible cFDR (Hutchinson et al. (2021) <doi:10.1371/journal.pgen.1009853>) and Binary cFDR (Hutchinson et al. (2021) <doi:10.1101/2021.10.21.465274>) methodologies to leverage auxiliary data from arbitrary distributions, for example functional genomic data, with GWAS p-values to generate re-weighted p-values.

Likelihood-free inference method for stochastic models. Uses a deterministic optimizer on simple simulations of the model that are performed with a prior drawn randomness by applying the inverse transform method. Is designed to work on its own and also by using the Julia package Jflimo available on the git page of the project: <https://metabarcoding.org/flimo>.

Generalized Entropy Calibration produces calibration weights using generalized entropy as the objective function for optimization. This approach, as implemented in the GECal package, is based on Kwon, Kim, and Qiu (2024) <doi:10.48550/arXiv.2404.01076>. GECal incorporates design weights into the constraints to maintain design consistency, rather than including them in the objective function itself.

Solves goal programming problems of the weighted and lexicographic type, as well as combinations of the two, as described by Ignizio (1983) <doi:10.1016/0305-0548(83)90003-5>. Allows for a simple human-readable input describing the problem as a series of equations. Relies on the lpSolve package to solve the underlying linear optimisation problem.

This package provides a function to retrieve the system timezone on Unix systems which has been found to find an answer when Sys.timezone() has failed. It is based on an answer by Duane McCully posted on StackOverflow', and adapted to be callable from R. The package also builds on Windows, but just returns NULL.

Estimates networks of conditional dependencies (Gaussian graphical models) from multiple classes of data (similar but not exactly, i.e. measurements on different equipment, in different locations or for various sub-types). Package also allows to generate simulation data and evaluate the performance. Implementation of the method described in Angelini, De Canditiis and Plaksienko (2022) <doi:10.3390/math10213983>.

Estimation of Latent Order Logistic (LOLOG) Models for Networks. LOLOGs are a flexible and fully general class of statistical graph models. This package provides functions for performing MOM, GMM and variational inference. Visual diagnostics and goodness of fit metrics are provided. See Fellows (2018) <doi:10.48550/arXiv.1804.04583> for a detailed description of the methods.

Random Forest Spatial Interpolation (RFSI, SekuliÄ et al. (2020) <doi:10.3390/rs12101687>) and spatio-temporal geostatistical (spatio-temporal regression Kriging (STRK)) interpolation for meteorological (Kilibarda et al. (2014) <doi:10.1002/2013JD020803>, SekuliÄ et al. (2020) <doi:10.1007/s00704-019-03077-3>) and other environmental variables. Contains global spatio-temporal models calculated using publicly available data.

It provides ensemble capabilities to supervised and unsupervised learning models predictions without using training labels. It decides the relative weights of the different models predictions by using best models predictions as response variable and rest of the mo. User can decide the best model, therefore, It provides freedom to user to ensemble models based on their design solutions.

Calculation of molecular number and brightness from fluorescence microscopy image series. The software was published in a 2016 paper <doi:10.1093/bioinformatics/btx434>. The seminal paper for the technique is Digman et al. 2008 <doi:10.1529/biophysj.107.114645>. A review of the technique was published in 2017 <doi:10.1016/j.ymeth.2017.12.001>.

Statistical methods for estimating preferential attachment and node fitness generative mechanisms in temporal complex networks are provided. Thong Pham et al. (2015) <doi:10.1371/journal.pone.0137796>. Thong Pham et al. (2016) <doi:10.1038/srep32558>. Thong Pham et al. (2020) <doi:10.18637/jss.v092.i03>. Thong Pham et al. (2021) <doi:10.1093/comnet/cnab024>.

Allows you to make clean, good-looking scatter plots with the option to easily add marginal density or box plots on the axes. It is also available as a module for jamovi (see <https://www.jamovi.org> for more information). Scatr is based on the cowplot package by Claus O. Wilke and the ggplot2 package by Hadley Wickham.

An implementation of Lind and Mehlum's (2010) <doi:10.1111/j.1468-0084.2009.00569.x> Utest to test for the presence of a U shaped or inverted U shaped relationship between variables in (generalized) linear models. It also implements a test of upward/downward sloping relationships at the lower and upper boundary of the data range.

Conducts linear regression using variational Bayesian inference, particularly optimized for genome-wide association mapping and whole-genome prediction which use a number of DNA markers as the explanatory variables. Provides seven regression models which select the important variables (i.e., the variables related to response variables) among the given explanatory variables in different ways (i.e., model structures).

Computes inequality measures of a given variable taking into account weights. Suitable for ratio, interval and ordered scale. Includes Gini, Theil, Leti index, Palma ratio, 20:20 ratio, Allison and Foster index, Jenkins index, Cowell and Flechaire index, Abul Naga and Yalcin index, Apouey index, Blair and Lacy index. Bootstrap provides distribution of inequality measures enabling significance tests.

The package is focused on the detection of correlation between expressed genes and selected epigenomic signals (i.e. enhancers obtained from ChIP-seq data) either within topologically associated domains (TADs) or between chromatin contact loop anchors. Various parameters can be controlled to investigate the influence of external factors and visualization plots are available for each analysis step.

This package provides functions for an Interactive Differential Expression AnaLysis of RNA-sequencing datasets, to extract quickly and effectively information downstream the step of differential expression. A Shiny application encapsulates the whole package. Support for reproducibility of the whole analysis is provided by means of a template report which gets automatically compiled and can be stored/shared.

sechm provides a simple interface between SummarizedExperiment objects and the ComplexHeatmap package. It enables plotting annotated heatmaps from SE objects, with easy access to rowData and colData columns, and implements a number of features to make the generation of heatmaps easier and more flexible. These functionalities used to be part of the SEtools package.

This package builds on the Epimods framework which facilitates finding weighted subnetworks ("modules") on Illumina Infinium 27k arrays using the SpinGlass algorithm, as implemented in the iGraph package. We have created a class of gene centric annotations associated with p-values and effect sizes and scores from any researchers prior statistical results to find functional modules.

The formr R package provides a few convenience functions that may be useful to the users of formr (formr.org), an online survey framework which heavily relies on R via openCPU. Some of the functions are for conveniently generating individual feedback graphics, some are just shorthands to make certain common operations in formr more palatable to R novices.

This package provides functions to convert origin-destination data, represented as straight desire lines in the sf Simple Features class system, into JSON files that can be directly imported into A/B Street <https://www.abstreet.org>, a free and open source tool for simulating urban transport systems and scenarios of change <doi:10.1007/s10109-020-00342-2>.

Finds the k nearest neighbours in a dataset of specified points, adding the option to wrap certain variables on a torus. The user chooses the algorithm to use to find the nearest neighbours. Two such algorithms, provided by the packages RANN <https://cran.r-project.org/package=RANN>, and nabor <https://cran.r-project.org/package=nabor>, are suggested.