This package provides a seamless interface to the MEME Suite family of tools for motif analysis. memes provides data aware utilities for using GRanges objects as entrypoints to motif analysis, data structures for examining & editing motif lists, and novel data visualizations. memes functions and data structures are amenable to both base R and tidyverse workflows.

This package implements a general purpose gene set analysis method called PADOG that downplays the importance of genes that apear often accross the sets of genes to be analyzed. The package provides also a benchmark for gene set analysis methods in terms of sensitivity and ranking using 24 public datasets from KEGGdzPathwaysGEO package.

The package offers statistical tests based on the 2-Wasserstein distance for detecting and characterizing differences between two distributions given in the form of samples. Functions for calculating the 2-Wasserstein distance and testing for differential distributions are provided, as well as a specifically tailored test for differential expression in single-cell RNA sequencing data.

This package performs estimation of marginal treatment effects for binary outcomes when using logistic regression working models with covariate adjustment (see discussions in Magirr et al (2024) <https://osf.io/9mp58/>). Implements the variance estimators of Ge et al (2011) <doi:10.1177/009286151104500409> and Ye et al (2023) <doi:10.1080/24754269.2023.2205802>.

Generate synthetic station-based monthly climate time-series including temperature and rainfall, export to Network Common Data Form (NetCDF), and provide visualization helpers for climate workflows. The approach is inspired by statistical weather generator concepts described in Wilks (1999) <doi:10.1016/S0168-1923(99)00037-4> and Richardson (1981) <doi:10.1029/WR017i001p00182>.

This package provides functions for cobin and micobin regression models, a new family of generalized linear models for continuous proportional data (Y in the closed unit interval [0, 1]). It also includes an exact, efficient sampler for the Kolmogorov-Gamma random variable. For details, see Lee et al. (2026) <doi:10.1080/01621459.2026.2626081>.

This package contains a large number of the goodness-of-fit tests for the Exponential and Weibull distributions classified into families: the tests based on the empirical distribution function, the tests based on the probability plot, the tests based on the normalized spacings, the tests based on the Laplace transform and the likelihood based tests.

This package contains functions to compute the functional tangential angle pseudo-depth and its robustified version from the paper by Kuhnt and Rehage (2016). See Kuhnt, S.; Rehage, A. (2016): An angle-based multivariate functional pseudo-depth for shape outlier detection, JMVA 146, 325-340, <doi:10.1016/j.jmva.2015.10.016> for details.

You can use this function to easily draw a combined histogram and restricted cubic spline. The function draws the graph through ggplot2'. RCS fitting requires the use of the rcs() function of the rms package. Can fit cox regression, logistic regression. This method was described by Per Kragh (2003) <doi:10.1002/sim.1497>.

Just analysis methods ('jam') base functions focused on bioinformatics. Version- and gene-centric alphanumeric sort, unique name and version assignment, colorized console and HTML output, color ramp and palette manipulation, Rmarkdown cache import, styled Excel worksheet import and export, interpolated raster output from smooth scatter and image plots, list to delimited vector, efficient list tools.

Efficient procedures for fitting the regularization path for linear, binomial, multinomial, Ising and Potts models with lasso, group lasso or column lasso(only for multinomial) penalty. The package uses Linearized Bregman Algorithm to solve the regularization path through iterations. Bregman Inverse Scale Space Differential Inclusion solver is also provided for linear model with lasso penalty.

Generalized Egger tests for detecting publication bias in meta-analysis for diagnostic accuracy test (Noma (2020) <doi:10.1111/biom.13343>, Noma (2022) <doi:10.48550/arXiv.2209.07270>). These publication bias tests are generally more powerful compared with the conventional univariate publication bias tests and can incorporate correlation information between the outcome variables.

Create and integrate thematic maps in your workflow. This package helps to design various cartographic representations such as proportional symbols, choropleth or typology maps. It also offers several functions to display layout elements that improve the graphic presentation of maps (e.g. scale bar, north arrow, title, labels). mapsf maps sf objects on base graphics.

The main functions perform mixed models analysis by least squares or REML by adding the function r() to formulas of lm() and glm(). A collection of text-book statistics for higher education is also included, e.g. modifications of the functions lm(), glm() and associated summaries from the package stats'.

Search and access transit feed data from the Mobility Database <https://mobilitydatabase.org>. The package wraps the Mobility Database API, allowing users to discover GTFS (General Transit Feed Specification) and GBFS (General Bikeshare Feed Specification) feeds from agencies worldwide. Functions are designed to integrate seamlessly with packages like tidytransit and gtfstools for subsequent feed analysis.

This package provides tools to handle, manipulate and explore trajectory data, with an emphasis on data from tracked animals. The package is designed to support large studies with several million location records and keep track of units where possible. Data import directly from movebank <https://www.movebank.org/cms/movebank-main> and files is facilitated.

This package provides a tidy, high-level interface for creating polished maps of Malawi at country, region, district, and Traditional Authority level. Functions handle spatial data retrieval, administrative-name matching, joins from ordinary data frames, numeric and categorical choropleths, labels, highlights, and professional ggplot2 styling. Spatial boundary data are provided by the companion package mwmapdata'.

Fits and selects zero-inflated mixed Poisson models for multivariate count regression. Supports multiple mixing distributions and variance specifications for flexible marginal modeling, while allowing dependence in the structural-zero components and latent mixing intensities to be modeled separately through copulas. The methodology is described in Nguyen (2026) <doi:10.48550/arXiv.2608.12732>.

This package implements the high-dimensional clustering technique Thresholding After Random Projections (n-TARP). Provides functionality to iteratively decompose larger datasets using contextual variables or within-cluster sum of squares. See Tarun & Boutin (2018) <doi:10.48550/arXiv.1806.05297> and Tarun & Boutin (2018) <doi:10.4231/R74B2ZJV> for the original method and applications.

Analyzing regression data with many and/or highly collinear predictor variables, by simultaneously reducing the predictor variables to a limited number of components and regressing the criterion variables on these components (de Jong S. & Kiers H. A. L. (1992) <doi:10.1016/0169-7439(92)80100-I>). Several rotation and model selection options are provided.

This package provides a spectral framework to map quantitative trait loci (QTLs) affecting joint differential networks of gene co-Expression. Test the equivalence among multiple biological networks via spectral statistics. See reference Hu, J., Weber, J. N., Fuess, L. E., Steinel, N. C., Bolnick, D. I., & Wang, M. (2025) <doi:10.1371/journal.pcbi.1012953>.

Facilitates extraction of geospatial data from the Office for National Statistics Open Geography and nomis Application Programming Interfaces (APIs). Simplifies process of querying nomis datasets <https://www.nomisweb.co.uk/> and extracting desired datasets in dataframe format. Extracts area shapefiles at chosen resolution from Office for National Statistics Open Geography <https://geoportal.statistics.gov.uk/>.

This package provides an imputation pipeline for single-cell RNA sequencing data. The scISR method uses a hypothesis-testing technique to identify zero-valued entries that are most likely affected by dropout events and estimates the dropout values using a subspace regression model (Tran et.al. (2022) <DOI:10.1038/s41598-022-06500-4>).

This package provides a set of functions and datasets implementation of small area estimation when auxiliary variable is measured with error. These functions provide a empirical best linear unbiased prediction (EBLUP) estimator and mean squared error (MSE) estimator of the EBLUP. These models were developed by Ybarra and Lohr (2008) <doi:10.1093/biomet/asn048>.