Robust multivariate estimation based on multivariate, composite and componentwise Density Power Divergence (DPD) minimization in multivariate normal distribution for casewise and cellwise contamination. Robust estimation for multivariate ordered gamma model using multivariate and composite DPD minimization. See A. Ghosh, C. Agostinelli, and A. Basu (2026) A Composite Divergence Approach to Robust Multivariate Estimation under Cellwise and Casewise Contamination. <doi:10.48550/arXiv.2608.18914> for full details.

Extract, transform and load MITRE standards. This package gives you an approach to cybersecurity data sets. All data sets are build on runtime downloading raw data from MITRE public services. MITRE <https://www.mitre.org/> is a government-funded research organization based in Bedford and McLean. Current version includes most used standards as data frames. It also provide a list of nodes and edges with all relationships.

MAle Lineage ANalysis by simulating genealogies backwards and imposing short tandem repeats (STR) mutations forwards. Intended for forensic Y chromosomal STR (Y-STR) haplotype analyses. Numerous analyses are possible, e.g. number of matches and meiotic distance to matches. Refer to papers mentioned in citation("malan") (DOI's: <doi:10.1371/journal.pgen.1007028>, <doi:10.21105/joss.00684> and <doi:10.1016/j.fsigen.2018.10.004>).

This package provides a multivariate zero inflated logistic normal regression model is implemented for compositional data with zero values present. The relevant paper is Li Z., Lee K., Karagas M. R., Madan J. C., Hoen A. G., O'Malley A. J. and Li H. (2018). "Conditional regression based on a multivariate zero-inflated logistic-normal model for microbiome relative abundance data", <doi:10.1007/s12561-018-9219-2>.

This package provides a Bayesian approach to estimate the number of occurred-but-not-yet-reported cases from incomplete, time-stamped reporting data for disease outbreaks. NobBS learns the reporting delay distribution and the time evolution of the epidemic curve to produce smoothed nowcasts in both stable and time-varying case reporting settings, as described in McGough et al. (2020) <doi:10.1371/journal.pcbi.1007735>.

Inspired by Moreira and Gamerman (2022) <doi:10.1214/21-AOAS1569>, this methodology expands the idea by including Marks in the point process. Using efficient C++ code, the estimation is possible and made faster with OpenMP <https://www.openmp.org/> enabled computers. This package was developed under the project PTDC/MAT-STA/28243/2017, supported by Portuguese funds through the Portuguese Foundation for Science and Technology (FCT).

Generates Proteomics (PTX) quality control (QC) reports for shotgun LC-MS data analyzed with the MaxQuant software suite (from .txt files) or mzTab files (ideally from OpenMS QualityControl tool). Reports are customizable (target thresholds, subsetting) and available in HTML or PDF format. Published in J. Proteome Res., Proteomics Quality Control: Quality Control Software for MaxQuant Results (2015) <doi:10.1021/acs.jproteome.5b00780>.

Implementation of PCMRS (Partial Credit Model with Response Styles) as proposed in by Tutz, Schauberger and Berger (2018) <doi:10.1177/0146621617748322> . PCMRS is an extension of the regular partial credit model. PCMRS allows for an additional person parameter that characterizes the response style of the person. By taking the response style into account, the estimates of the item parameters are less biased than in partial credit models.

Fetch and clean data from the World Database on Protected Areas (WDPA) and the World Database on Other Effective Area-Based Conservation Measures (WDOECM). Data is obtained from Protected Planet <https://www.protectedplanet.net/en>. To augment data cleaning procedures, users can install the prepr R package (available at <https://github.com/prioritizr/prepr>). For more information on this package, see Hanson (2022) <doi:10.21105/joss.04594>.

provides a functions for generating spectra libraries that can be used for MRM SRM MS workflows in proteomics. The package provides a BiblioSpec reader, a function which can add the protein information using a FASTA formatted amino acid file, and an export method for using the created library in the Spectronaut software. The package is developed, tested and used at the Functional Genomics Center Zurich <https://fgcz.ch>.

Hydrological modelling tools developed at INRAE-Antony (HYCAR Research Unit, France). The package includes several conceptual rainfall-runoff models (GR4H, GR5H, GR4J, GR5J, GR6J, GR2M, GR1A) that can be applied either on a lumped or semi-distributed way. A snow accumulation and melt model (CemaNeige) and the associated functions for the calibration and evaluation of models are also included. Use help(airGR) for package description and references.

Assess whether and how a specific continuous or categorical exposure affects the outcome of interest through one- or multi-dimensional mediators using an adaptive bootstrap (AB) approach. The AB method allows to make inference for composite null hypotheses of no mediation effect, providing valid type I error control and thus optimizes statistical power. For more technical details, refer to He, Song and Xu (2024) <doi:10.1093/jrsssb/qkad129>.

This package provides a modern view on the principal component analysis biplot with calibrated axes. Create principal component analysis biplots rendered in HTML with significant reactivity embedded within the plot. Furthermore, the traditional biplot view is enhanced by translated axes with inter-class kernel densities superimposed. For more information on biplots, see Gower, J.C., Lubbe, S. and le Roux, N.J. (2011, ISBN: 978-0-470-01255-0).

By adding over-relaxation factor to PXEM (Parameter Expanded Expectation Maximization) method, the MOPXEM (Monotonically Overrelaxed Parameter Expanded Expectation Maximization) method is obtained. Compare it with the existing EM (Expectation-Maximization)-like methods. Then, distribute and process five methods and compare them, achieving good performance in convergence speed and result quality.The philosophy of the package is described in Guo G. (2022) <doi:10.1007/s00180-022-01270-z>.

This package implements the locally efficient doubly robust difference-in-differences (DiD) estimators for the average treatment effect proposed by Sant'Anna and Zhao (2020) <doi:10.1016/j.jeconom.2020.06.003>. The estimator combines inverse probability weighting and outcome regression estimators (also implemented in the package) to form estimators with more attractive statistical properties. Two different estimation methods can be used to estimate the nuisance functions.

This package provides a collection of routines for evaluating data from larger forest management units, typically sample inventories, but also stand-wise inventories. The idea is to support modern forest planning approaches and to be open by design to new data sources and evaluation methods. For the methodological background of forest inventories see Kangas and Maltamo (2006) "Forest Inventory: Methodology and Applications" <doi:10.1007/1-4020-4381-3>.

This package implements general unilateral loading estimator for two-layer latent factor models with smooth, element-wise factor transformations. We provide data simulation, loading estimation,finite-sample error bounds, and diagnostic tools for zero-mean and sub-Gaussian assumptions. A unified interface is given for evaluating estimation accuracy and cosine similarity. The philosophy of the package is described in Guo G. (2026) <doi:10.1016/j.apm.2025.116280>.

The gamma lasso algorithm provides regularization paths corresponding to a range of non-convex cost functions between L0 and L1 norms. As much as possible, usage for this package is analogous to that for the glmnet package (which does the same thing for penalization between L1 and L2 norms). For details see: Taddy (2017 JCGS), One-Step Estimator Paths for Concave Regularization', <doi:10.48550/arXiv.1308.5623>.

Flexible procedures to compute local density-based outlier scores for ranking outliers. Both exact and approximate nearest neighbor search can be implemented, while also accommodating multiple neighborhood sizes and four different local density-based methods. It allows for referencing a random subsample of the input data or a user specified reference data set to compute outlier scores against, so both unsupervised and semi-supervised outlier detection can be implemented.

Calculates and differentiates probabilities and density of (conditional) multivariate normal distribution and Gaussian copula (with various marginal distributions) using methods described in A. Genz (2004) <doi:10.1023/B:STCO.0000035304.20635.31>, A. Genz, F. Bretz (2009) <doi:10.1007/978-3-642-01689-9>, H. I. Gassmann (2003) <doi:10.1198/1061860032283> and E. Kossova, B. Potanin (2018) <https://ideas.repec.org/a/ris/apltrx/0346.html>.

This package provides methods and tools for deriving spatial summary functions from single-cell imaging data and performing functional data analyses. Functions can be applied to other single-cell technologies such as spatial transcriptomics. Functional regression and functional principal component analysis methods are in the refund package <https://cran.r-project.org/package=refund> while calculation of the spatial summary functions are from the spatstat package <https://spatstat.org/>.

Test-based Image structural similarity measure and test of independence. This package implements the key functions of two tasks: (1) computing image structural similarity measure PSSIM of Wang, Maldonado and Silwal (2011) <DOI:10.1016/j.csda.2011.04.021>; and (2) test of independence between a response and a covariate in presence of heteroscedastic treatment effects proposed by Wang, Tolos, and Wang (2010) <DOI:10.1002/cjs.10068>.

This package provides a novel pseudo-value regression approach for the differential co-expression network analysis in expression data, which can incorporate additional clinical variables in the model. This is a direct regression modeling for the differential network analysis, and it is therefore computationally amenable for the most users. The full methodological details can be found in Ahn S et al (2023) <doi:10.1186/s12859-022-05123-w>.

This package provides various styles of function chaining methods: Pipe operator, Pipe object, and pipeline function, each representing a distinct pipeline model yet sharing almost a common set of features: A value can be piped to the first unnamed argument of a function and to dot symbol in an enclosed expression. The syntax is designed to make the pipeline more readable and friendly to a wide range of operations.