The ESTIMATE package infers tumor purity from expression data as a function of immune and stromal infiltrate, but requires writing of intermediate files, is un-pipeable, and performs poorly when presented with modern datasets with current gene symbols. tidyestimate a fast, tidy, modern reimagination of ESTIMATE (2013) <doi:10.1038/ncomms3612>.

Collection of ancillary functions and utilities to be used in conjunction with the TraMineR package for sequence data exploration. Includes, among others, specific functions such as state survival plots, position-wise group-typical states, dynamic sequence indicators, and dissimilarities between event sequences. Also includes contributions by non-members of the TraMineR team such as methods for polyadic data and for the comparison of groups of sequences.

Characterisation of the extremal dependence structure of time series, avoiding pre-processing and filtering as done typically with peaks-over-threshold methods. It uses the conditional approach of Heffernan and Tawn (2004) <DOI:10.1111/j.1467-9868.2004.02050.x> which is very flexible in terms of extremal and asymptotic dependence structures, and Bayesian methods improve efficiency and allow for deriving measures of uncertainty. For example, the extremal index, related to the size of clusters in time, can be estimated and samples from its posterior distribution obtained.

How can we measure how the usage or frequency of some feature, such as words, differs across some group or set, such as documents? One option is to use the log odds ratio, but the log odds ratio alone does not account for sampling variability; we haven't counted every feature the same number of times so how do we know which differences are meaningful? Enter the weighted log odds, which tidylo provides an implementation for, using tidy data principles. In particular, here we use the method outlined in Monroe, Colaresi, and Quinn (2008) <doi:10.1093/pan/mpn018> to weight the log odds ratio by a prior. By default, the prior is estimated from the data itself, an empirical Bayes approach, but an uninformative prior is also available.

This package implements triple-difference (DDD) estimators for both average treatment effects and event-study parameters. Methods include regression adjustment, inverse-probability weighting, and doubly-robust estimators, all of which rely on a conditional DDD parallel-trends assumption and allow covariate adjustment across multiple pre- and post-treatment periods. The methodology is detailed in Ortiz-Villavicencio and Sant'Anna (2025) <doi:10.48550/arXiv.2505.09942>.

Factor and autoregressive models for matrix and tensor valued time series. We provide functions for estimation, simulation and prediction. The models are discussed in Li et al (2021) <doi:10.48550/arXiv.2110.00928>, Chen et al (2020) <DOI:10.1080/01621459.2021.1912757>, Chen et al (2020) <DOI:10.1016/j.jeconom.2020.07.015>, and Xiao et al (2020) <doi:10.48550/arXiv.2006.02611>.

Analyse data from longitudinal studies to characterise changes in values of semi-quantitative outcome variables within individual subjects, using high performance C++ code to enable rapid processing of large datasets. A flexible methodology is available for codifying these state transitions.

Transforms long data into a matrix form to allow for ease of input into modelling packages for regression, principal components, imputation or machine learning. It does this by pivoting on user defined columns, generating a key-value table for variable names to ensure one-to-one mappings are preserved. It is particularly useful when the indicator names in the columns are long descriptive strings, for example "Energy imports, net (% of energy use)". High level analysis wrapper functions for correlation and principal components analysis are provided.

Download summary files from Census Bureau <https://www2.census.gov/> and extract data, in particular high resolution data at block, block group, and tract level, from decennial census and American Community Survey 1-year and 5-year estimates.

This package provides a type system for R. It supports setting variable types in a script or the body of a function, so variables can't be assigned illegal values. Moreover it supports setting argument and return types for functions.

Perform a Visual Predictive Check (VPC), while accounting for stratification, censoring, and prediction correction. Using piping from magrittr', the intuitive syntax gives users a flexible and powerful method to generate VPCs using both traditional binning and a new binless approach Jamsen et al. (2018) <doi:10.1002/psp4.12319> with Additive Quantile Regression (AQR) and Locally Estimated Scatterplot Smoothing (LOESS) prediction correction.

Key-value store, implemented as a wrapper around LMDB'; the "lightning memory-mapped database" <https://www.symas.com/mdb>. LMDB is a transactional key value store that uses a memory map for efficient access. This package wraps the entire LMDB interface (except duplicated keys), and provides objects for transactions and cursors.

Builds tables with customizable rows. Users can specify the type of data to use for each row, as well as how to handle missing data and the types of comparison tests to run on the table columns.

This package performs the detection of linear trend changes for univariate time series by implementing the bottom-up unbalanced wavelet transformation proposed by H. Maeng and P. Fryzlewicz (2023). The estimated number and locations of the change-points are returned with the piecewise-linear estimator for signal.

This queue is a data structure that lets parallel processes send and receive messages, and it can help coordinate the work of complicated parallel tasks. Processes can push new messages to the queue, pop old messages, and obtain a log of all the messages ever pushed. File locking preserves the integrity of the data even when multiple processes access the queue simultaneously.

This package performs Three-Mode Principal Components Analysis, which carries out Tucker Models.

The LSTM (Long Short-Term Memory) model is a Recurrent Neural Network (RNN) based architecture that is widely used for time series forecasting. Customizable configurations for the model are allowed, improving the capabilities and usability of this model compared to other packages. This package is based on keras and tensorflow modules and the algorithm of Paul and Garai (2021) <doi:10.1007/s00500-021-06087-4>.

Create "good enough" tables with a single formula. tablespan tables can be exported to Excel', HTML', LaTeX', and RTF by leveraging the packages openxlsx and gt'. See <https://jhorzek.github.io/tablespan/> for an introduction.

An inverse probability of censoring weighted (IPCW) targeted maximum likelihood estimator (TMLE) for evaluating a marginal point treatment effect from data where some variables were collected on only a subset of participants using a two-stage design (or marginal mean outcome for a single arm study). A TMLE for conditional parameters defined by a marginal structural model (MSM) is also available.

This package provides a screening process utilizing training and testing samples to filter out uninformative DNA methylation sites. Surrogate variables (SVs) of DNA methylation are included in the filtering process to explain unknown factor effects.

This package provides a terribly-simple data base for numeric time series, written purely in R, so no external database-software is needed. Series are stored in plain-text files (the most-portable and enduring file type) in CSV format. Timestamps are encoded using R's native numeric representation for Date'/'POSIXct', which makes them fast to parse, but keeps them accessible with other software. The package provides tools for saving and updating series in this standardised format, for retrieving and joining data, for summarising files and directories, and for coercing series from and to other data types (such as zoo series).

Implementation of a Bayesian two-way latent structure model for integrative genomic clustering. The model clusters samples in relation to distinct data sources, with each subject-dataset receiving a latent cluster label, though cluster labels have across-dataset meaning because of the model formulation. A common scaling across data sources is unneeded, and inference is obtained by a Gibbs Sampler. The model can fit multivariate Gaussian distributed clusters or a heavier-tailed modification of a Gaussian density. Uniquely among integrative clustering models, the formulation makes no nestedness assumptions of samples across data sources -- the user can still fit the model if a study subject only has information from one data source. The package provides a variety of post-processing functions for model examination including ones for quantifying observed alignment of clusterings across genomic data sources. Run time is optimized so that analyses of datasets on the order of thousands of features on fewer than 5 datasets and hundreds of subjects can converge in 1 or 2 days on a single CPU. See "Swanson DM, Lien T, Bergholtz H, Sorlie T, Frigessi A, Investigating Coordinated Architectures Across Clusters in Integrative Studies: a Bayesian Two-Way Latent Structure Model, 2018, <doi:10.1101/387076>, Cold Spring Harbor Laboratory" at <https://www.biorxiv.org/content/early/2018/08/07/387076.full.pdf> for model details.

This package provides tools to download data series from Banco de España ('BdE') on tibble format. Banco de España is the national central bank and, within the framework of the Single Supervisory Mechanism ('SSM'), the supervisor of the Spanish banking system along with the European Central Bank. This package is in no way sponsored endorsed or administered by Banco de España'.

Efficient method for fitting nonparametric matrix trace regression model. The detailed description can be found in C. Lee, L. Li, H. Zhang, and M. Wang (2021). Nonparametric Trace Regression via Sign Series Representation. <arXiv:2105.01783>. The method employs the aggregation of structured sign series for trace regression (ASSIST) algorithm.