This package performs an analysis of time-to-event clinical trial data using various "win time" methods, including ewt', ewtr', rmt', ewtp', rewtp', ewtpr', rewtpr', max', wtr', rwtr', pwt', and rpwt'. These methods are used to calculate and compare treatment effects on ordered composite endpoints. The package handles event times, event indicators, and treatment arm indicators and supports calculations on observed and resampled data. Detailed explanations of each method and usage examples are provided in "Use of win time for ordered composite endpoints in clinical trials," by Troendle et al. (2024)<https://pubmed.ncbi.nlm.nih.gov/38417455/>. For more information, see the package documentation or the vignette titled "Introduction to wintime.".

An interface to WordNet using the Jawbone Java API to WordNet. WordNet (<https://wordnet.princeton.edu/>) is a large lexical database of English. Nouns, verbs, adjectives and adverbs are grouped into sets of cognitive synonyms (synsets), each expressing a distinct concept. Synsets are interlinked by means of conceptual-semantic and lexical relations. Please note that WordNet(R) is a registered tradename. Princeton University makes WordNet available to research and commercial users free of charge provided the terms of their license (<https://wordnet.princeton.edu/license-and-commercial-use>) are followed, and proper reference is made to the project using an appropriate citation (<https://wordnet.princeton.edu/citing-wordnet>). The WordNet database files need to be made available separately, either via package wordnetDicts from <https://datacube.wu.ac.at>, installing system packages where available, or direct download from <https://wordnetcode.princeton.edu/3.0/WNdb-3.0.tar.gz>.

This package provides data from the United Nation's World Population Prospects 2015.

This package implements various win ratio methodologies for composite endpoints of death and non-fatal events, including the (stratified) proportional win-fractions (PW) regression models (Mao and Wang, 2020 <doi:10.1111/biom.13382>), (stratified) two-sample tests with possibly recurrent nonfatal event, and sample size calculation for standard win ratio test (Mao et al., 2021 <doi:10.1111/biom.13501>).

Organizational framework for web development in R including functions to serve static and dynamic content via HTTP methods, includes the html5 package to create HTML pages, and offers other utility functions for common tasks related to web development.

This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.

This package provides efficient implementation of the Wild Binary Segmentation and Binary Segmentation algorithms for estimation of the number and locations of multiple change-points in the piecewise constant function plus Gaussian noise model.

This package provides survival analysis functions with support for time-dependent and subject-specific (e.g., propensity score) weighting. Implements weighted estimation for Cox models, Kaplan-Meier survival curves, and treatment differences with point-wise and simultaneous confidence bands. Includes restricted mean survival time (RMST) comparisons evaluated across all potential truncation times with both point-wise and simultaneous confidence bands. See Cole, S. R. & Hernán, M. A. (2004) <doi:10.1016/j.cmpb.2003.10.004> for methodological background.

This package provides automated downloading, parsing and formatting of weather data for Australia through API endpoints provided by the Department of Primary Industries and Regional Development (DPIRD) of Western Australia and by the Science and Technology Division of the Queensland Government's Department of Environment and Science (DES). As well as the Bureau of Meteorology (BOM) of the Australian government precis and coastal forecasts, and downloading and importing radar and satellite imagery files. DPIRD weather data are accessed through public APIs provided by DPIRD, <https://www.dpird.wa.gov.au/online-tools/apis/>, providing access to weather station data from the DPIRD weather station network. Australia-wide weather data are based on data from the Australian Bureau of Meteorology (BOM) data and accessed through SILO (Scientific Information for Land Owners) Jeffrey et al. (2001) <doi:10.1016/S1364-8152(01)00008-1>. DPIRD data are made available under a Creative Commons Attribution 3.0 Licence (CC BY 3.0 AU) license <https://creativecommons.org/licenses/by/3.0/au/deed.en>. SILO data are released under a Creative Commons Attribution 4.0 International licence (CC BY 4.0) <https://creativecommons.org/licenses/by/4.0/>. BOM data are (c) Australian Government Bureau of Meteorology and released under a Creative Commons (CC) Attribution 3.0 licence or Public Access Licence (PAL) as appropriate, see <http://www.bom.gov.au/other/copyright.shtml> for further details.

Search and download data from over 40 databases hosted by the World Bank, including the World Development Indicators ('WDI'), International Debt Statistics, Doing Business, Human Capital Index, and Sub-national Poverty indicators.

Logging of scripts suitable for clinical trials using Quarto to create nice human readable logs. whirl enables execution of scripts in batch, while simultaneously creating logs for the execution of each script, and providing an overview summary log of the entire batch execution.

This package provides a framework for developing n-gram models for text prediction. It provides data cleaning, data sampling, extracting tokens from text, model generation, model evaluation and word prediction. For information on how n-gram models work we referred to: "Speech and Language Processing" <https://web.archive.org/web/20240919222934/https%3A%2F%2Fweb.stanford.edu%2F~jurafsky%2Fslp3%2F3.pdf>. For optimizing R code and using R6 classes we referred to "Advanced R" <https://adv-r.hadley.nz/r6.html>. For writing R extensions we referred to "R Packages", <https://r-pkgs.org/index.html>.

For a given Sentence-Aligned Parallel Corpus, it aligns words for each sentence pair. It considers one-to-many and symmetrization alignments. Moreover, it evaluates the quality of word alignment based on this package and some other software. It also builds an automatic dictionary of two languages based on given parallel corpus.

In the course of a genome-wide association study, the situation often arises that some phenotypes are known with greater precision than others. It could be that some individuals are known to harbor more micro-environmental variance than others. In the case of inbred strains of model organisms, it could be the case that more organisms were observed from some strains than others, so the strains with more organisms have better-estimated means. Package wISAM handles this situation by allowing for weighting of each observation according to residual variance. Specifically, the weight parameter to the function conduct_scan() takes the precision of each observation (one over the variance).

Calculates the WEGE (Weighted Endemism including Global Endangerment index) index for a particular area. Additionally it also calculates rasters of KBA's (Key Biodiversity Area) criteria (A1a, A1b, A1e, and B1), Weighted endemism (WE), the EDGE (Evolutionarily Distinct and Globally Endangered) score, Evolutionary Distinctiveness (ED) and Extinction risk (ER). Farooq, H., Azevedo, J., Belluardo F., Nanvonamuquitxo, C., Bennett, D., Moat, J., Soares, A., Faurby, S. & Antonelli, A. (2020) <doi:10.1101/2020.01.17.910299>.

Taxonomic information from Wikipedia', Wikicommons', Wikispecies', and Wikidata'. Functions included for getting taxonomic information from each of the sources just listed, as well performing taxonomic search.

This method generates a tour path by interpolating between d-D frames in p-D using Givens rotations. The algorithm arises from the problem of zeroing elements of a matrix. This interpolation method is useful for showing specific d-D frames in the tour, as opposed to d-D planes, as done by the geodesic interpolation. It is useful for projection pursuit indexes which are not s invariant. See more details in Buj, Cook, Asimov and Hurley (2005) <doi:10.1016/S0169-7161(04)24014-7> and Batsaikhan, Cook and Laa (2023) <doi:10.48550/arXiv.2311.08181>.

Assess Water Quality Trends for Long-Term Monitoring Data in Estuaries using Generalized Additive Models following Wood (2017) <doi:10.1201/9781315370279> and Error Propagation with Mixed-Effects Meta-Analysis following Sera et al. (2019) <doi:10.1002/sim.8362>. Methods are available for model fitting, assessment of fit, annual and seasonal trend tests, and visualization of results.

Create plots and tables in a consistent style with WaSHI (Washington Soil Health Initiative) branding. Use washi to easily style your ggplot2 plots and flextable tables.

Create dense vector representation of words and documents using quanteda'. Implements Word2vec (Mikolov et al., 2013) <doi:10.48550/arXiv.1310.4546>, Doc2vec (Le & Mikolov, 2014) <doi:10.48550/arXiv.1405.4053> and Latent Semantic Analysis (Deerwester et al., 1990) <doi:10.1002/(SICI)1097-4571(199009)41:6%3C391::AID-ASI1%3E3.0.CO;2-9>.

This package provides a hierarchy of classes and methods for manipulating matrices formed implicitly from the sums of the inverses of other matrices, a situation commonly encountered in spatial statistics and related fields. Enables easy use of the Woodbury matrix identity and the matrix determinant lemma to allow computation (e.g., solving linear systems) without having to form the actual matrix. More information on the underlying linear algebra can be found in Harville, D. A. (1997) <doi:10.1007/b98818>.

Efficient Bayesian generalized linear models with time-varying coefficients as in Helske (2022, <doi:10.1016/j.softx.2022.101016>). Gaussian, Poisson, and binomial observations are supported. The Markov chain Monte Carlo (MCMC) computations are done using Hamiltonian Monte Carlo provided by Stan, using a state space representation of the model in order to marginalise over the coefficients for efficient sampling. For non-Gaussian models, the package uses the importance sampling type estimators based on approximate marginal MCMC as in Vihola, Helske, Franks (2020, <doi:10.1111/sjos.12492>).

Wavelet decomposes a series into multiple sub series called detailed and smooth components which helps to capture volatility at multi resolution level by various models. Two hybrid Machine Learning (ML) models (Artificial Neural Network and Support Vector Regression have been used) have been developed in combination with stochastic models, feature selection, and optimization algorithms for prediction of the data. The algorithms have been developed following Paul and Garai (2021) <doi:10.1007/s00500-021-06087-4>.

Calculate magnetic field at a given location and time according to the World Magnetic Model (WMM). Both the main field and secular variation components are returned. This functionality is useful for physicists and geophysicists who need orthogonal components from WMM. Currently, this package supports annualized time inputs between 2000 and 2025. If desired, users can specify which WMM version to use, e.g., the original WMM2015 release or the recent out-of-cycle WMM2015 release. Methods used to implement WMM, including the Gauss coefficients for each release, are described in the following publications: Chulliat et al (2020) <doi:10.25923/ytk1-yx35>, Chulliat et al (2019) <doi:10.25921/xhr3-0t19>, Chulliat et al (2015) <doi:10.7289/V5TB14V7>, Maus et al (2010) <https://www.ngdc.noaa.gov/geomag/WMM/data/WMMReports/WMM2010_Report.pdf>, McLean et al (2004) <https://www.ngdc.noaa.gov/geomag/WMM/data/WMMReports/TRWMM_2005.pdf>, and Macmillian et al (2000) <https://www.ngdc.noaa.gov/geomag/WMM/data/WMMReports/wmm2000.pdf>.