Plot stacked areas and confidence bands as filled polygons, or add polygons to existing plots. A variety of input formats are supported, including vectors, matrices, data frames, formulas, etc.

Compute a tree level hierarchy, judgment matrix, consistency index and ratio, priority vectors, hierarchic synthesis and rank. Based on the book entitled "Models, Methods, Concepts and Applications of the Analytic Hierarchy Process" by Saaty and Vargas (2012, ISBN 978-1-4614-3597-6).

Convert several png files into an animated png file. This package exports only a single function `apng'. Call the apng function with a vector of file names (which should be png files) to convert them to a single animated png file.

This package provides tools for constructing a matched design with multiple comparison groups. Further specifications of refined covariate balance restriction and exact match on covariate can be imposed. Matches are approximately optimal in the sense that the cost of the solution is at most twice the optimal cost, Crama and Spieksma (1992) <doi:10.1016/0377-2217(92)90078-N>, Karmakar, Small and Rosenbaum (2019) <doi:10.1080/10618600.2019.1584900>.

Programming vaccine specific Clinical Data Interchange Standards Consortium (CDISC) compliant Analysis Data Model (ADaM) datasets in R'. Flat model is followed as per Center for Biologics Evaluation and Research (CBER) guidelines for creating vaccine specific domains. ADaM datasets are a mandatory part of any New Drug or Biologics License Application submitted to the United States Food and Drug Administration (FDA). Analysis derivations are implemented in accordance with the "Analysis Data Model Implementation Guide" (CDISC Analysis Data Model Team (2021), <https://www.cdisc.org/standards/foundational/adam/adamig-v1-3-release-package>). The package is an extension package of the admiral package.

This package implements several basic algorithms for estimating regression parameters for semiparametric accelerated failure time (AFT) model. The main methods are: Jin rank-based method (Jin (2003) <doi:10.1093/biomet/90.2.341>), Hellerâ s estimating method (Heller (2012) <doi:10.1198/016214506000001257>), Polynomial smoothed Gehan function method (Chung (2013) <doi:10.1007/s11222-012-9333-9>), Buckley-James method (Buckley (1979) <doi:10.2307/2335161>) and Jin`s improved least squares method (Jin (2006) <doi:10.1093/biomet/93.1.147>). This package can be used for modeling right-censored data and for comparing different estimation algorithms.

This package implements a hierarchical penalized spline framework for estimating achievement gap trajectories in longitudinal educational data. The achievement gap between two groups (e.g., low versus high socioeconomic status) is modeled directly as a smooth function of grade while the baseline trajectory is estimated simultaneously within a mixed-effects model. Smoothing parameters are selected using restricted maximum likelihood (REML), and simultaneous confidence bands with correct joint coverage are constructed using posterior simulation. The package also includes functions for simulation-based benchmarking, visualization of gap trajectories, and hypothesis testing for global and grade-specific differences. The modeling framework builds on penalized spline methods (Eilers and Marx, 1996, <doi:10.1214/ss/1038425655>) and generalized additive modeling approaches (Wood, 2017, <doi:10.1201/9781315370279>), with uncertainty quantification following Marra and Wood (2012, <doi:10.1111/j.1467-9469.2011.00760.x>).

Fit pharmacokinetic/pharmacodynamic (PK/PD) models to aggregate-level data (mean vector and covariance matrix per study) rather than individual-level data. Integrates with the nlmixr2'/'rxode2 ecosystem via three estimation methods: a First-Order ('FO') analytical estimator, a Monte Carlo (MC) estimator, and an Iterative Reweighting Monte Carlo ('IRMC') estimator. Methods are based on Välitalo (2021) <doi:10.1007/s10928-021-09760-1>; software described in van de Beek et al. (2025) <doi:10.1007/s10928-025-10011-w>.

The empirical cumulative average deviation function introduced by the author is utilized to develop both Ad- and Ud-plots. The Ad-plot can identify symmetry, skewness, and outliers of the data distribution, including anomalies. The Ud-plot created by slightly modifying Ad-plot is exceptional in assessing normality, outperforming normal QQ-plot, normal PP-plot, and their derivations. The d-value that quantifies the degree of proximity between the Ud-plot and the graph of the estimated normal density function helps guide to make decisions on confirmation of normality. Full description of this methodology can be found in the article by Wijesuriya (2025) <doi:10.1080/03610926.2024.2440583>.

Perform parallel factor analysis (PARAFAC: Hitchcock, 1927) <doi:10.1002/sapm192761164> on fluorescence excitation-emission matrices: handle scattering signal and inner filter effect, scale the dataset, fit the model; perform split-half validation or jack-knifing. Modified approaches such as Whittaker interpolation, randomised split-half, and fluorescence and scattering model estimation are also available. The package has a low dependency footprint and has been tested on a wide range of R versions.

Fetching data from Amazon Kinesis Streams using the Java-based MultiLangDaemon interacting with Amazon Web Services ('AWS') for easy stream processing from R. For more information on Kinesis', see <https://aws.amazon.com/kinesis>.

This package provides tools for the quantitative analysis of axon integrity in microscopy images. It implements image pre-processing, adaptive thresholding, feature extraction, and support vector machine-based classification to compute indices such as the Axon Integrity Index (AII) and Degeneration Index (DI). The package is designed for reproducible and automated analysis in neuroscience research.

Generate code for use with the Optical Mark Recognition free software Auto Multiple Choice (AMC). More specifically, this package provides functions that use as input the question and answer texts, and output the LaTeX code for AMC.

Interface to the Azure Machine Learning Software Development Kit ('SDK'). Data scientists can use the SDK to train, deploy, automate, and manage machine learning models on the Azure Machine Learning service. To learn more about Azure Machine Learning visit the website: <https://docs.microsoft.com/en-us/azure/machine-learning/service/overview-what-is-azure-ml>.

Algorithms for automatically finding appropriate thresholds for numerical data, with special functions for thresholding images. Provides the ImageJ Auto Threshold plugin functionality to R users. See <https://imagej.net/plugins/auto-threshold> and Landini et al. (2017) <DOI:10.1111/jmi.12474>.

The functions defined in this program serve for implementing adaptive two-stage tests. Currently, four tests are included: Bauer and Koehne (1994), Lehmacher and Wassmer (1999), Vandemeulebroecke (2006), and the horizontal conditional error function. User-defined tests can also be implemented. Reference: Vandemeulebroecke, An investigation of two-stage tests, Statistica Sinica 2006.

Generate spreadsheet publications that follow best practice guidance from the UK government's Analysis Function, available at <https://analysisfunction.civilservice.gov.uk/policy-store/releasing-statistics-in-spreadsheets/>, with a focus on accessibility. See also the Python package gptables'.

Facilitates access to the data from the Atlas do Estado Brasileiro (<https://www.ipea.gov.br/atlasestado/>), maintained by the Instituto de Pesquisa Econômica Aplicada (Ipea). It allows users to search for specific series, list series or themes, and download data when available.

This package provides different functionalities and calculations used in the world of basketball to analyze the statistics of the players, the statistics of the teams, the statistics of the quintets and the statistics of the plays. For more details of the calculations included in the package can be found in the book Basketball on Paper written by Dean Oliver.

Nonparametric data-driven approach to discovering heterogeneous subgroups in a selection-on-observables framework. aggTrees allows researchers to assess whether there exists relevant heterogeneity in treatment effects by generating a sequence of optimal groupings, one for each level of granularity. For each grouping, we obtain point estimation and inference about the group average treatment effects. Please reference the use as Di Francesco (2022) <doi:10.2139/ssrn.4304256>.

This package provides an interface in R to cell atlas approximations. See the vignette under "Getting started" for instructions. You can also explore the reference documentation for specific functions. Additional interfaces and resources are available at <https://atlasapprox.readthedocs.io>.

Simulate the effect of management or demography on allele retention and inbreeding accumulation in bottlenecked populations of animals with overlapping generations.

Functionality to allow users to easily colour plots with the colour palettes of various academic institutions.

Nonparametric estimation of additive isotonic covariate effects for proportional hazards model.