This package provides dependency-free helpers for recurring numerical tasks on vectors, matrices, and arrays. Operations cover bounds, interpolation, remapping, division, Euclidean norms, normalization, and adjacent differences. Multi-input operations use strict scalar recycling, reject incompatible lengths, and preserve names, dimensions, and dimension names where applicable. Explicit handling of invalid intervals, zero denominators, and zero norms gives consistent behavior for common edge cases.

This package provides nonparametric procedures for the analysis of longitudinal data in factorial experiments. The package implements hypothesis tests on marginal distribution functions and unweighted relative marginal effects. It supports arbitrary crossed factorial designs with longitudinal or repeated-measures factors, missing observations, dependent replicates, rank- and pseudo-rank-based inference, Wald-type and ANOVA-type statistics, multiple contrast tests, and simultaneous confidence intervals.

Additive proportional odds model for ordinal data using Laplace P-splines. The combination of Laplace approximations and P-splines enable fast and flexible inference in a Bayesian framework. Specific approximations are proposed to account for the asymmetry in the marginal posterior distributions of non-penalized parameters. For more details, see Lambert and Gressani (2023) <doi:10.1177/1471082X231181173> ; Preprint: <arXiv:2210.01668>).

Tool for producing Pen's parade graphs, useful for visualizing inequalities in income, wages or other variables, as proposed by Pen (1971, ISBN: 978-0140212594). Income or another economic variable is captured by the vertical axis, while the population is arranged in ascending order of income along the horizontal axis. Pen's income parades provide an easy-to-interpret visualization of economic inequalities.

The goal of SAFEPG is to predict climate-related extreme losses by fitting a frequency-severity model. It improves predictive performance by introducing a sign-aligned regularization term, which ensures consistent signs for the coefficients across the frequency and severity components. This enhancement not only increases model accuracy but also enhances its interpretability, making it more suitable for practical applications in risk assessment.

This package provides a fast implementation of the SWAG algorithm for Generalized Linear Models which allows to perform a meta-learning procedure that combines screening and wrapper methods to find a set of extremely low-dimensional attribute combinations. The package then performs test on the network of selected models to identify the variables that are highly predictive by using entropy-based network measures.

This package provides functions to build datasets ready for statistical analysis from camera trap data: GLMM/GAMM on counts/RAI at various temporal levels, group size, occupancy, kernel/circular analysis of activity patterns, temporal interactions between species, hierarchical diel models, and classic capture-mark-recapture. Input data must be formatted in the style produced by camtrapR', the standard convention in the field.

Decode raw SYNOP (surface synoptic observations) messages into data frames, extracting data from Sections 0, 1, and 3, including temperature, dew point, pressure, wind, clouds, and precipitation. Available functions to download SYNOP messages from Ogimet <https://www.ogimet.com/> if needed. The decoding logic follows the specifications defined in the World Meteorological Organization (2019) "Manual on Codes, Volume I.1 (WMO-No. 306)".

This package provides tools for modeling non-continuous linear responses of ecological communities to environmental data. The package is straightforward through three steps: (1) data ordering (function OrdData()), (2) split-moving-window analysis (function SMW()) and (3) piecewise redundancy analysis (function pwRDA()). Relevant references include Cornelius and Reynolds (1991) <doi:10.2307/1941559> and Legendre and Legendre (2012, ISBN: 9780444538697).

This package provides a Tcl/Tk Graphical User Interface (GUI) to display images than can be zoomed and panned using the mouse and keyboard shortcuts. tkImgR read and write different image formats (PPM/PGM, PNG and GIF) using the standard Tcl/Tk distribution (>=8.6), but other formats (JPEG, TIFF, CR2) can be handled using the tkImg package for Tcl/Tk'.

Utilities for restricted mean survival time (RMST) and time-varying restricted mean survival time quantities computed from survival curves provided on a time grid. The package is model-agnostic and accepts only a time vector and survival matrices, returning RMST-based quantities and bootstrap summaries. For restricted mean survival time methodology, see Royston and Parmar (2013) <doi:10.1186/1471-2288-13-152>.

This package provides functions for defining and conducting a time series prediction process including pre(post)processing, decomposition, modelling, prediction and accuracy assessment. The generated models and its yielded prediction errors can be used for benchmarking other time series prediction methods and for creating a demand for the refinement of such methods. For this purpose, benchmark data from prediction competitions may be used.

This package infers the V genotype of an individual from immunoglobulin (Ig) repertoire sequencing data (AIRR-Seq, Rep-Seq). Includes detection of any novel alleles. This information is then used to correct existing V allele calls from among the sample sequences. Citations: Gadala-Maria, et al (2015) <doi:10.1073/pnas.1417683112>, Gadala-Maria, et al (2019) <doi:10.3389/fimmu.2019.00129>.

The vcfpp.h (<https://github.com/Zilong-Li/vcfpp>) provides an easy-to-use C++ API of htslib', offering full functionality for manipulating Variant Call Format (VCF) files. The vcfppR package serves as the R bindings of the vcfpp.h library, enabling rapid processing of both compressed and uncompressed VCF files. Explore a range of powerful features for efficient VCF data manipulation.

An implementation of three procedures developed by John Tukey: FUNOP (FUll NOrmal Plot), FUNOR-FUNOM (FUll NOrmal Rejection-FUll NOrmal Modification), and vacuum cleaner. Combined, they provide a way to identify, treat, and analyze outliers in two-way (i.e., contingency) tables, as described in his landmark paper "The Future of Data Analysis", Tukey, John W. (1962) <https://www.jstor.org/stable/2237638>.

Inverse normal transformation (INT) based genetic association testing. These tests are recommend for continuous traits with non-normally distributed residuals. INT-based tests robustly control the type I error in settings where standard linear regression does not, as when the residual distribution exhibits excess skew or kurtosis. Moreover, INT-based tests outperform standard linear regression in terms of power. These tests may be classified into two types. In direct INT (D-INT), the phenotype is itself transformed. In indirect INT (I-INT), phenotypic residuals are transformed. The omnibus test (O-INT) adaptively combines D-INT and I-INT into a single robust and statistically powerful approach. See McCaw ZR, Lane JM, Saxena R, Redline S, Lin X. "Operating characteristics of the rank-based inverse normal transformation for quantitative trait analysis in genome-wide association studies" <doi:10.1111/biom.13214>.

This package provides tools to derive species-level phylogenies from large synthesis mega-trees for a wide range of taxonomic groups, including plants, birds, mammals, amphibians, reptiles, fish, bees, butterflies, and sharks. When a queried species is absent from the mega-tree, it is grafted onto the tree using one of two placement strategies: attachment at the basal node of the most closely related genus or family ('at_basal_node'), or random attachment below that basal node with probability proportional to branch length ('random_below_basal'). See Li (2023) <doi:10.1111/ecog.06643> for details. Multiple species from a genus not represented in the mega-tree are placed as a polytomy to preserve clade coherence. The package interfaces with the megatrees data package, which bundles or downloads on demand curated mega-trees. Users can also provide their own mega-trees.

satuRn provides a framework for performing differential transcript usage analyses. The package consists of three main functions. The first function, fitDTU, fits quasi-binomial generalized linear models that model transcript usage in different groups of interest. The second function, testDTU, tests for differential usage of transcripts between groups of interest. Finally, plotDTU visualizes the usage profiles of transcripts in groups of interest.

This package provides support for numerical and graphical summaries of RNA-Seq genomic read data. Provided within-lane normalization procedures to adjust for GC-content effect (or other gene-level effects) on read counts: loess robust local regression, global-scaling, and full-quantile normalization. Between-lane normalization procedures to adjust for distributional differences between lanes (e.g., sequencing depth): global-scaling and full-quantile normalization.

This package is used to detect combination of genomic coordinates falling within a user defined window size along with user defined overlap between identified neighboring clusters. It can be used for genomic data where the clusters are built on a specific chromosome or specific strand. Clustering can be performed with a "greedy" option allowing thus the presence of additional sites within the allowed window size.

This package provides a graphics device for R that is accessible via network protocols. This package was created to make it easier to embed live R graphics in integrated development environments and other applications. The included HTML/JavaScript client (plot viewer) aims to provide a better overall user experience when dealing with R graphics. The device asynchronously serves graphics via HTTP and WebSockets'.

This package contains diverse functionality to extend the usage of the iSEE package, including additional classes for the panels or modes facilitating the analysis of differential expression results. This package does not perform differential expression. Instead, it provides methods to embed precomputed differential expression results in a SummarizedExperiment object, in a manner that is compatible with interactive visualisation in iSEE applications.

`orthos` decomposes RNA-seq contrasts, for example obtained from a gene knock-out or compound treatment experiment, into unspecific and experiment-specific components. Original and decomposed contrasts can be efficiently queried against a large database of contrasts (derived from ARCHS4, https://maayanlab.cloud/archs4/) to identify similar experiments. `orthos` furthermore provides plotting functions to visualize the results of such a search for similar contrasts.

Comprehensive R package for differential composition and variability analysis in single-cell RNA sequencing, CyTOF, and microbiome data. Provides robust Bayesian modeling with outlier detection, random effects, and advanced statistical methods for cell type proportion analysis. Features include probabilistic outlier identification, mixed-effect modeling, differential variability testing, and comprehensive visualization tools. Perfect for cancer research, immunology, developmental biology, and single-cell genomics applications.