The current version of the MixSAL package allows users to generate data from a multivariate SAL distribution or a mixture of multivariate SAL distributions, evaluate the probability density function of a multivariate SAL distribution or a mixture of multivariate SAL distributions, and fit a mixture of multivariate SAL distributions using the Expectation-Maximization (EM) algorithm (see Franczak et. al, 2014, <doi:10.1109/TPAMI.2013.216>, for details).

Fast functions implemented in C++ via Rcpp to support the NeuroAnatomy Toolbox ('nat') ecosystem. These functions provide large speed-ups for basic manipulation of neuronal skeletons over pure R functions found in the nat package. The expectation is that end users will not use this package directly, but instead the nat package will automatically use routines from this package when it is available to enable large performance gains.

Infer system functioning with empirical NETwork COMparisons. These methods are part of a growing paradigm in network science that uses relative comparisons of networks to infer mechanistic classifications and predict systemic interventions. They have been developed and applied in Langendorf and Burgess (2021) <doi:10.1038/s41598-021-99251-7>, Langendorf (2020) <doi:10.1201/9781351190831-6>, and Langendorf and Goldberg (2019) <doi:10.48550/arXiv.1912.12551>.

This package provides tools for managing nested, multi-level configuration systems with runtime mutability, type validation, and default value management. Supports creating hierarchical options managers with customizable validators for scalar and vector types (numeric, character, logical), enumerated values, bounded ranges, and complex structures like XY pairs. Options can be dynamically modified at runtime while maintaining type safety through validator functions, and easily reset to their default values when needed.

This package implements the Quantile Autoregressive Distributed Lag (QARDL) model of Cho, Kim and Shin (2015) <doi:10.1016/j.jeconom.2015.01.003>. Estimates quantile-specific long-run (beta), short-run autoregressive (phi), and impact (gamma) parameters. Features include BIC-based automatic lag selection, Error Correction Model (ECM) parameterization, Wald tests for parameter constancy across quantiles, rolling/recursive QARDL estimation, Monte Carlo simulation, and publication-ready output tables.

Derives stratified prevalence tables from the condition, procedure, and drug records in OMOP CDM (Observational Medical Outcomes Partnership Common Data Model) databases, computes log2 prevalence ratios between paired datasets, and synthesizes them via random-effects meta-analysis at multiple aggregation levels (year, age group, and sex). Between-study variance is estimated with the Paule-Mandel method, as described in Paule and Mandel (1982) <doi:10.6028/jres.087.022>.

Add-on for the scan package that creates plots from single-case data frames ('scdf'). It includes functions for styling single-case plots, adding phase-based lines to indicate various statistical parameters, and predefined themes for presentations and publications. More information and in depth examples can be found in the online book "Analyzing Single-Case Data with R and scan" Jürgen Wilbert (2026) <https://jazznbass.github.io/scan-Book/>.

Implementation of the family of generalised age-period-cohort stochastic mortality models. This family of models encompasses many models proposed in the actuarial and demographic literature including the Lee-Carter (1992) <doi:10.2307/2290201> and the Cairns-Blake-Dowd (2006) <doi:10.1111/j.1539-6975.2006.00195.x> models. It includes functions for fitting mortality models, analysing their goodness-of-fit and performing mortality projections and simulations.

This package provides a collection of recipe datasets scraped from <https://www.allrecipes.com/>, containing two complementary datasets: allrecipes with 14,426 general recipes, and cuisines with 2,218 recipes categorized by country of origin. Both datasets include comprehensive recipe information such as ingredients, nutritional facts (calories, fat, carbs, protein), cooking times (preparation and cooking), ratings, and review metadata. All data has been cleaned and standardized, ready for analysis.

Matching terminal restriction fragment length polymorphism ('TRFLP') profiles between unknown samples and a database of known samples. TRAMPR facilitates analysis of many unknown profiles at once, and provides tools for working directly with electrophoresis output through to generating summaries suitable for community analyses with R's rich set of statistical functions. TRAMPR also resolves the issues of multiple TRFLP profiles within a species, and shared TRFLP profiles across species.

Tidy tools for NetCDF data sources. Explore the contents of a NetCDF source (file or URL) presented as variables organized by grid with a database-like interface. The hyper_filter() interactive function translates the filter value or index expressions to array-slicing form. No data is read until explicitly requested, as a data frame or list of arrays via hyper_tibble() or hyper_array().

This package provides half-normal plots, reference plots, and Pareto plots of effects from an unreplicated experiment, along with various pseudo-standard-error measures, simulated reference distributions, and other tools. Many of these methods are described in Daniel C. (1959) <doi:10.1080/00401706.1959.10489866> and/or Lenth R.V. (1989) <doi:10.1080/00401706.1989.10488595>, but some new approaches are added and integrated in one package.

Estimates hierarchical models using variational inference. At present, it can estimate logistic, linear, and negative binomial models. It can accommodate models with an arbitrary number of random effects and requires no integration to estimate. It also provides the ability to improve the quality of the approximation using marginal augmentation. Goplerud (2022) <doi:10.1214/21-BA1266> and Goplerud (2024) <doi:10.1017/S0003055423000035> provide details on the variational algorithms.

This package provides tools are provided for estimating, testing, and simulating abundance in a two-event (Petersen) mark-recapture experiment. Functions are given to calculate the Petersen, Chapman, and Bailey estimators and associated variances. However, the principal utility is a set of functions to simulate random draws from these estimators, and use these to conduct hypothesis tests and power calculations. Additionally, a set of functions are provided for generating confidence intervals via bootstrapping. Functions are also provided to test abundance estimator consistency under complete or partial stratification, and to calculate stratified or partially stratified estimators. Functions are also provided to calculate recommended sample sizes. Referenced methods can be found in Arnason et al. (1996) <ISSN:0706-6457>, Bailey (1951) <DOI:10.2307/2332575>, Bailey (1952) <DOI:10.2307/1913>, Chapman (1951) NAID:20001644490, Cohen (1988) ISBN:0-12-179060-6, Darroch (1961) <DOI:10.2307/2332748>, and Robson and Regier (1964) <ISSN:1548-8659>.

This package provides Ion Trap positive ionization mode data in mzML file format. It includes a subset from 500-850 m/z and 1190-1310 seconds, including MS2 and MS3, intensity threshold 100.000; extracts from FTICR Apex III, m/z 400-450; a subset of UPLC - Bruker micrOTOFq data, both mzML and mz5; LC-MSMS and MRM files from proteomics experiments; and PSI mzIdentML example files for various search engines.

This package provides a data.frame processor/conditioner that prepares real-world data for predictive modeling in a statistically sound manner. vtreat prepares variables so that data has fewer exceptional cases, making it easier to safely use models in production. Common problems vtreat defends against: Inf, NA, too many categorical levels, rare categorical levels, and new categorical levels (levels seen during application, but not during training).

Network Common Data Form (netCDF) files are widely used for scientific data. Library-level access in R is provided through packages RNetCDF and ncdf4. The package ncdfCF is built on top of RNetCDF and makes the data and its attributes available as a set of R6 classes that are informed by the Climate and Forecasting Metadata Conventions. Access to the data uses standard R subsetting operators and common function forms.

Biological studies often consist of multiple conditions which are examined with different laboratory set ups like RNA-sequencing or ChIP-sequencing. To get an overview about the whole resulting data set, Cogito provides an automated, complete, reproducible and clear report about all samples and basic comparisons between all different samples. This report can be used as documentation about the data set or as starting point for further custom analysis.

This package integrates colocalization probabilities from colocalization analysis with transcriptome-wide association study (TWAS) scan summary statistics to implicate genes that may be biologically relevant to a complex trait. The probabilistic framework implemented in this package constrains the TWAS scan z-score-based likelihood using a gene-level colocalization probability. Given gene set annotations, this package can estimate gene set enrichment using posterior probabilities from the TWAS-colocalization integration step.

This package contains the Summix2 method for estimating and adjusting for substructure in genetic summary allele frequency data. The function summix() estimates reference group proportions using a mixture model. The adjAF() function produces adjusted allele frequencies for an observed group with reference group proportions matching a target individual or sample. The summix_local() function estimates local ancestry mixture proportions and performs selection scans in genetic summary data.

Uniparental disomy (UPD) is a genetic condition where an individual inherits both copies of a chromosome or part of it from one parent, rather than one copy from each parent. This package contains a HMM for detecting UPDs through HTS (High Throughput Sequencing) data from trio assays. By analyzing the genotypes in the trio, the model infers a hidden state (normal, father isodisomy, mother isodisomy, father heterodisomy and mother heterodisomy).

This package provides tools to construct (or add to) cell-type signature matrices using flow sorted or single cell samples and deconvolve bulk gene expression data. Useful for assessing the quality of single cell RNAseq experiments, estimating the accuracy of signature matrices, and determining cell-type spillover. Please cite: Danziger SA et al. (2019) ADAPTS: Automated Deconvolution Augmentation of Profiles for Tissue Specific cells <doi:10.1371/journal.pone.0224693>.

This package implements several tools that are used in animal social network analysis, as described in Whitehead (2007) Analyzing Animal Societies <University of Chicago Press> and Farine & Whitehead (2015) <doi: 10.1111/1365-2656.12418>. In particular, this package provides the tools to infer groups and generate networks from observation data, perform permutation tests on the data, calculate lagged association rates, and performed multiple regression analysis on social network data.

Auto-GO is a framework that enables automated, high quality Gene Ontology enrichment analysis visualizations. It also features a handy wrapper for Differential Expression analysis around the DESeq2 package described in Love et al. (2014) <doi:10.1186/s13059-014-0550-8>. The whole framework is structured in different, independent functions, in order to let the user decide which steps of the analysis to perform and which plot to produce.