This package provides tools for estimating sample sizes primarily based on heritability, while also considering additional parameters such as statistical power and fold change. The package normalizes heritability values according to trait-specific heritability and classification to enhance accuracy in sample size estimation.

Generates HIDECAN plots that summarise and combine the results of genome-wide association studies (GWAS) and transcriptomics differential expression analyses (DE), along with manually curated candidate genes of interest. The HIDECAN plot is presented in Angelin-Bonnet et al. (2023) (currently in review).

Allows access to data from the Rio de Janeiro Public Security Institute (ISP), such as criminal statistics, data on gun seizures and femicide. The package also contains the spatial data of Pacifying Police Units (UPPs) and Integrated Public Safety Regions, Areas and Circumscriptions.

ISA is a metadata framework to manage an increasingly diverse set of life science, environmental and biomedical experiments. In isatabr methods for reading, modifying and writing of files in the ISA-Tab format are implemented. It also contains methods for processing assay data.

Multi-step adaptive elastic-net (MSAENet) algorithm for feature selection in high-dimensional regressions proposed in Xiao and Xu (2015) <DOI:10.1080/00949655.2015.1016944>, with support for multi-step adaptive MCP-net (MSAMNet) and multi-step adaptive SCAD-net (MSASNet) methods.

This package performs treatment allocation in two-arm clinical trials by the maximal procedure described by Berger et al. (2003) <doi:10.1002/sim.1538>. To that end, the algorithm provided by Salama et al. (2008) <doi:10.1002/sim.3014> is implemented.

This package provides tools for animal movement modelling using hidden Markov models. These include processing of tracking data, fitting hidden Markov models to movement data, visualization of data and fitted model, decoding of the state process, etc. <doi:10.1111/2041-210X.12578>.

This package provides a collection of functions to connect to a Moodle database, cache relevant tables locally and generate learning analytics. Moodle is an open source Learning Management System (LMS) developed by MoodleHQ. For more information about Moodle, visit <https://moodle.org>.

An interface to easily run local language models with Ollama <https://ollama.com> server and API endpoints (see <https://github.com/ollama/ollama/blob/main/docs/api.md> for details). It lets you run open-source large language models locally on your machine.

Makes output files from select PreSens Fiber Optic Oxygen Transmitters easier to work with in R. See <http://www.presens.de> for more information about PreSens (Precision Sensing GmbH). Note: this package is neither created nor maintained by PreSens.

Download and generate summaries for the rodent, plant, ant, and weather data from the Portal Project. Portal is a long-term (and ongoing) experimental monitoring site in the Chihuahuan desert. The raw data files can be found at <https://github.com/weecology/portaldata>.

Generates simple and beautiful one-page HTML reference manuals with package documentation. Math rendering and syntax highlighting are done server-side in R such that no JavaScript libraries are needed in the browser, which makes the documentation portable and fast to load.

This package provides a set of datasets and functions used in the book Modele liniowe i mieszane w R, wraz z przykladami w analizie danych'. Datasets either come from real studies or are created to be as similar as possible to real studies.

Chooses subgroup specific optimal doses in a phase I dose finding clinical trial allowing for subgroup combination and simulates clinical trials under the subgroup specific time to event continual reassessment method. Chapple, A.G., Thall, P.F. (2018) <doi:10.1002/pst.1891>.

Estimation of an S-shaped function and its corresponding inflection point via a least squares approach. A sequential mixed primal-dual based algorithm is implemented for the fast computation. Details can be found in Feng et al. (2022) <doi:10.1111/rssb.12481>.

This package provides a sparklyr extension package providing an integration with Google BigQuery'. It supports direct import/export where records are directly streamed from/to BigQuery'. In addition, data may be imported/exported via intermediate data extracts on Google Cloud Storage'.

Likelihood-based methods for model fitting and assessment, prediction and intervention analysis of count time series following generalized linear models are provided. Models with the identity and with the logarithmic link function are allowed. The conditional distribution can be Poisson or Negative Binomial.

Generate tables, listings, and graphs (TLG) using tidyverse. Tables can be created functionally, using a standard TLG process, or by specifying table and column metadata to create generic analysis summaries. The envsetup package can also be leveraged to create environments for table creation.

Extends invariant causal prediction (Peters et al., 2016, <doi:10.1111/rssb.12167>) to generalized linear and transformation models (Hothorn et al., 2018, <doi:10.1111/sjos.12291>). The methodology is described in Kook et al. (2023, <doi:10.1080/01621459.2024.2395588>).

This package implements a James-Stein-type shrinkage estimator for the covariance matrix, with separate shrinkage for variances and correlations. Furthermore, functions are available for fast singular value decomposition, for computing the pseudoinverse, and for checking the rank and positive definiteness of a matrix.

This package provides an implementation of evaluation metrics in R that are commonly used in supervised machine learning. It implements metrics for regression, time series, binary classification, classification, and information retrieval problems. It has zero dependencies and a consistent, simple interface for all functions.

This package performs the Baumgartner-Weiss-Schindler two-sample test of equal probability distributions (doi:10.2307/2533862). It also performs similar rank-based tests for equal probability distributions due to Neuhauser (doi:10.1080/10485250108832874) and Murakami (doi:10.1080/00949655.2010.551516).

svglite is a graphics device that produces clean SVG (Scalable Vector Graphics) output, suitable for use on the web, or hand editing. Compared to the built-in svg(), svglite is considerably faster, produces smaller files, and leaves text as is.

NanoString nCounter is a medium-throughput platform that measures gene or microRNA expression levels. Here is a publication that introduces this platform: Malkov (2009) <doi:10.1186/1756-0500-2-80>. Here is the webpage of NanoString nCounter where you can find detailed information about this platform <https://www.nanostring.com/scientific-content/technology-overview/ncounter-technology>. It has great clinical application, such as diagnosis and prognosis of cancer. Implements integrated system of random-coefficient hierarchical regression model to normalize data from NanoString nCounter platform so that noise from various sources can be removed.