An instrumental variable estimator under structural cumulative additive intensity model is fitted, that leverages initial randomization as the IV. The estimator can be used to fit an additive hazards model under time to event data which handles treatment switching (treatment crossover) correctly. We also provide a consistent variance estimate.

Regression models for interval censored data. Currently supports Cox-PH, proportional odds, and accelerated failure time models. Allows for semi and fully parametric models (parametric only for accelerated failure time models) and Bayesian parametric models. Includes functions for easy visual diagnostics of model fits and imputation of censored data.

The Lorentz transform in special relativity; also the gyrogroup structure of three-velocities. Performs active and passive transforms and has the ability to use units in which the speed of light is not unity. Includes some experimental functionality for celerity and rapidity. For general relativity, see the schwarzschild package.

Create custom labels, badges, certificates and other documents. Automate the production of potentially large numbers of herbarium and collection labels, accreditation badges, attendance and participation certificates, etc, and deliver them automatically. Documents are generated in PDF format, which requires a working installation of LaTeX', such as TinyTeX'.

This is a R implementation of "Minimum SNPs" software as described in "Price E.P., Inman-Bamber, J., Thiruvenkataswamy, V., Huygens, F and Giffard, P.M." (2007) <doi:10.1186/1471-2105-8-278> "Computer-aided identification of polymorphism sets diagnostic for groups of bacterial and viral genetic variants.".

Estimation of models with dependent variable left-censored at zero. Null values may be caused by a selection process Cragg (1971) <doi:10.2307/1909582>, insufficient resources Tobin (1958) <doi:10.2307/1907382>, or infrequency of purchase Deaton and Irish (1984) <doi:10.1016/0047-2727(84)90067-7>.

Computing metabolite set enrichment analysis (MSEA) (Yamamoto, H. et al. (2014) <doi:10.1186/1471-2105-15-51>), single sample enrichment analysis (SSEA) (Yamamoto, H. (2023) <doi:10.51094/jxiv.262>) and over-representation analysis (ORA) that accounts for undetected metabolites (Yamamoto, H. (2024) <doi:10.51094/jxiv.954>).

This package implements the out-of-treatment testing from Kuelpmann and Kuzmics (2020) <doi:10.2139/ssrn.3441675> based on the Vuong Test introduced in Vuong (1989) <doi:10.2307/1912557>. Out-of treatment testing allows for a direct, pairwise likelihood comparison of theories, calibrated with pre-existing data.

Collection (syllogi in greek) of real and fictitious data sets for teaching purposes. The datasets were manually entered by the author from the respective references as listed in the individual dataset documentation. The fictions datasets are the creation of the author, that he has found useful for teaching statistics.

An automatic cluster-based annotation pipeline based on evidence-based score by matching the marker genes with known cell markers in tissue-specific cell taxonomy reference database for single-cell RNA-seq data. See Shao X, et al (2020) <doi:10.1016/j.isci.2020.100882> for more details.

An object oriented framework to simulate ecological (and other) dynamic systems. It can be used for differential equations, individual-based (or agent-based) and other models as well. It supports structuring of simulation scenarios (to avoid copy and paste) and aims to improve readability and re-usability of code.

Simulates the cultural evolution of quantitative traits of bird song. SongEvo is an individual- (agent-) based model. SongEvo is spatially-explicit and can be parameterized with, and tested against, measured song data. Functions are available for model implementation, sensitivity analyses, parameter optimization, model validation, and hypothesis testing.

Provide regularized principal component analysis incorporating smoothness, sparseness and orthogonality of eigen-functions by using the alternating direction method of multipliers algorithm (Wang and Huang, 2017, <DOI:10.1080/10618600.2016.1157483>). The method can be applied to either regularly or irregularly spaced data, including 1D, 2D, and 3D.

This package implements an efficient O(n) algorithm based on bucket-sorting for fast computation of standard clustering comparison measures. Available measures include adjusted Rand index (ARI), normalized information distance (NID), normalized mutual information (NMI), adjusted mutual information (AMI), normalized variation information (NVI) and entropy.

This package provides a platform-independent API to access the operating system's credential store. It currently supports Keychain on macOS, Credential Store on Windows, the Secret Service API on GNU/Linux, and a simple, platform independent store implemented with environment variables. Additional storage back-ends can be added easily.

Libretro is a simple but powerful development interface that allows for the easy creation of emulators, games and multimedia applications that can plug straight into any libretro-compatible frontend. RetroArch is the official reference frontend for the libretro API, currently used by most as a modular multi-system game/emulator system.

Robustness checks for omitted variable bias. The package includes robustness checks proposed by Oster (2019). The robomit package computes i) the bias-adjusted treatment correlation or effect and ii) the degree of selection on unobservables relative to observables (with respect to the treatment variable) that would be necessary to eliminate the result based on the framework by Oster (2019). The code is based on the psacalc command in Stata'. Additionally, robomit offers a set of sensitivity analysis and visualization functions. See Oster, E. 2019. <doi:10.1080/07350015.2016.1227711>. Additionally, see Diegert, P., Masten, M. A., & Poirier, A. (2022) for a recent discussion of the topic: <doi:10.48550/arXiv.2206.02303>.

Using this package, you can fit a random effects model using either the hierarchical credibility model, a combination of the hierarchical credibility model with a generalized linear model or a Tweedie generalized linear mixed model. See Campo, B.D.C. and Antonio, K. (2023) <doi:10.1080/03461238.2022.2161413>.

Allows the user to determine minimum sample sizes that achieve target size and power at a specified alternative. For more information, see â Exact samples sizes for clinical trials subject to size and power constraintsâ by Lloyd, C.J. (2022) Preprint <doi:10.13140/RG.2.2.11828.94085>.

Compute alpha and beta contributional diversity metrics, which is intended for linking taxonomic and functional microbiome data. See GitHub repository for the tutorial: <https://github.com/gavinmdouglas/FuncDiv/wiki>. Citation: Gavin M. Douglas, Sunu Kim, Morgan G. I. Langille, B. Jesse Shapiro (2023) <doi:10.1093/bioinformatics/btac809>.

This package provides a collection of methods for modeling time-to-event data using both functional and scalar predictors. It implements functional data analysis techniques for estimation and inference, allowing researchers to assess the impact of functional covariates on survival outcomes, including time-to-single event and recurrent event outcomes.

Compute labels for a test set according to the k-Nearest Neighbors classification. This is a fast way to do k-Nearest Neighbors classification because the distance matrix -between the features of the observations- is an input to the function rather than being calculated in the function itself every time.

This package provides a fast and flexible implementation of Callaway and Sant'Anna's (2021)<doi:10.1016/j.jeconom.2020.12.001> staggered Difference-in-Differences (DiD) estimators, fastdid reduces the computation time from hours to seconds, and incorporates extensions such as time-varying covariates and multiple events.

Shiny apps can often make use of the same key elements, this package provides modules for common tasks (data upload, wrangling data, figure generation and saving the app state), and also a framework for developing. These modules can react and interact as well as generate code to create reproducible analyses.