Growing collection of helper functions for point pattern analysis. Most functions are designed to work with the spatstat (<http://spatstat.org>) package. The focus of most functions are either null models or summary functions for spatial point patterns. For a detailed description of all null models and summary functions, see Wiegand and Moloney (2014, ISBN:9781420082548).

This package provides a convenient framework for aggregating and disaggregating continuously varying parameters (for example, case fatality ratio, with age) for proper parametrization of lower-resolution compartmental models (for example, with broad age categories) and subsequent upscaling of model outputs to high resolution (for example, as needed when calculating age-sensitive measures like years-life-lost).

Implementation of penalized regression with second-generation p-values for variable selection. The algorithm can handle linear regression, GLM, and Cox regression. S3 methods print(), summary(), coef(), predict(), and plot() are available for the algorithm. Technical details can be found at Zuo et al. (2021) <doi:10.1080/00031305.2021.1946150>.

Three-dimensional systematic conservation planning, conducting nested prioritization analyses across multiple depth levels and ensuring efficient resource allocation throughout the water column. It provides a structured workflow designed to address biodiversity conservation and management challenges in the 3 dimensions, while facilitating usersâ choices and parameterization (Doxa et al. 2025 <doi:10.1016/j.ecolmodel.2024.110919>).

This package implements the "Residual (Sur)Realism" algorithm described by Stefanski (2007) <doi:10.1198/000313007X190079> to generate datasets that reveal hidden images or messages in their residual plots. It offers both predefined datasets and tools to embed custom text or images into residual structures. Allowing users to create intriguing visual demonstrations for teaching model diagnostics.

This package provides a collection of functions for data analysis with two-by-two contingency tables. The package provides tools to compute measures of effect (odds ratio, risk ratio, and risk difference), calculate impact numbers and attributable fractions, and perform hypothesis testing. Statistical analysis methods are oriented towards epidemiological investigation of relationships between exposures and outcomes.

Interface to easily access data via the United States Department of Agriculture (USDA)'s Livestock Mandatory Reporting ('LMR') Data API at <https://mpr.datamart.ams.usda.gov/>. The downloaded data can be saved for later off-line use. Also provide relevant information and metadata for each of the input variables needed for sending the data inquiry.

This package provides a method to refit and correct the diploid region in copy number profiles. It uses a clustering algorithm to identify pathology-specific normal (diploid) chromosomes and then use their copy number signal to refit the whole profile. The package is composed by three functions: DRrefit (the main function), ComputeNormalChromosome and PlotCluster.

The hdxmsqc package enables us to analyse and visualise the quality of HDX-MS experiments. Either as a final quality check before downstream analysis and publication or as part of a interative procedure to determine the quality of the data. The package builds on the QFeatures and Spectra packages to integrate with other mass-spectrometry data.

The r-nleqslv package solves a system of nonlinear equations using a Broyden or a Newton method with a choice of global strategies such as line search and trust region. There are options for using a numerical or user supplied Jacobian, for specifying a banded numerical Jacobian and for allowing a singular or ill-conditioned Jacobian.

This package is an R package designed for QC, analysis, and exploration of single cell RNA-seq data. It easily enables widely-used analytical techniques, including the identification of highly variable genes, dimensionality reduction; PCA, ICA, t-SNE, standard unsupervised clustering algorithms; density clustering, hierarchical clustering, k-means, and the discovery of differentially expressed genes and markers.

This package provides a Bayesian credible interval is interpreted with respect to posterior probability, and this interpretation is far more intuitive than that of a frequentist confidence interval. However, standard highest-density intervals can be wide due to between-subjects variability and tends to hide within-subject effects, rendering its relationship with the Bayes factor less clear in within-subject (repeated-measures) designs. This urgent issue can be addressed by using within-subject intervals in within-subject designs, which integrate four methods including the Wei-Nathoo-Masson (2023) <doi:10.3758/s13423-023-02295-1>, the Loftus-Masson (1994) <doi:10.3758/BF03210951>, the Nathoo-Kilshaw-Masson (2018) <doi:10.1016/j.jmp.2018.07.005>, and the Heck (2019) <doi:10.31234/osf.io/whp8t> interval estimates.

Integrated tools to support rigorous and well documented data harmonization based on Maelstrom Research guidelines. The package includes functions to assess and prepare input elements, apply specified processing rules to generate harmonized datasets, validate data processing and identify processing errors, and document and summarize harmonized outputs. The harmonization process is defined and structured by two key user-generated documents: the DataSchema (specifying the list of harmonized variables to generate across datasets) and the Data Processing Elements (specifying the input elements and processing algorithms to generate harmonized variables in DataSchema formats). The package was developed to address key challenges of retrospective data harmonization in epidemiology (as described in Fortier I and al. (2017) <doi:10.1093/ije/dyw075>) but can be used for any data harmonization initiative.

Make summary tables for descriptive statistics and select explanatory variables automatically in various regression models. Support linear models, generalized linear models and cox-proportional hazard models. Generate publication-ready tables summarizing result of regression analysis and plots. The tables and plots can be exported in "HTML", "pdf('LaTex')", "docx('MS Word')" and "pptx('MS Powerpoint')" documents.

Offers several functions for Configural Frequencies Analysis (CFA), which is a useful statistical tool for the analysis of multiway contingency tables. CFA was introduced by G. A. Lienert as Konfigurations Frequenz Analyse - KFA'. Lienert, G. A. (1971). Die Konfigurationsfrequenzanalyse: I. Ein neuer Weg zu Typen und Syndromen. Zeitschrift für Klinische Psychologie und Psychotherapie, 19(2), 99â 115.

Dependent censoring regression models for survival multivariate data. These models are based on extensions of the frailty models, capable to accommodating the dependence between failure and censoring times, with Weibull and piecewise exponential marginal distributions. Theoretical details regarding the models implemented in the package can be found in Schneider et al. (2019) <doi:10.1002/bimj.201800391>.

This package provides various statistical methods for evaluating Individualized Treatment Rules under randomized data. The provided metrics include Population Average Value (PAV), Population Average Prescription Effect (PAPE), Area Under Prescription Effect Curve (AUPEC). It also provides the tools to analyze Individualized Treatment Rules under budget constraints. Detailed reference in Imai and Li (2019) <arXiv:1905.05389>.

This package provides a system to facilitate designing comparative (and non-comparative) experiments using the grammar of experimental designs <https://emitanaka.org/edibble-book/>. An experimental design is treated as an intermediate, mutable object that is built progressively by fundamental experimental components like units, treatments, and their relation. The system aids in experimental planning, management and workflow.

This package provides a collection of utility functions for working with Year Month Day objects. Includes functions for fast parsing of numeric and character input based on algorithms described in Hinnant, H. (2021) <https://howardhinnant.github.io/date_algorithms.html> as well as a branchless calculation of leap years by Jerichaux (2025) <https://stackoverflow.com/a/79564914>.

Extends the fitdist() (from fitdistrplus') adding the Anderson-Darling ad.test() (from ADGofTest') and Kolmogorov Smirnov Test ks.test() inside, trying the distributions from stats package by default and offering a second function which uses mixed distributions to fit, this distributions are split with unsupervised learning, with Mclust() function (from mclust').

Read Swiss time series data from the KOF Data API, <https://datenservice.kof.ethz.ch>. The API provides macro economic time series data mostly about Switzerland. The package itself is a set of wrappers around the KOF Datenservice API. The kofdata package is able to consume public information as well as data that requires an API token.

Access business registration data from the Dutch Chamber of Commerce (Kamer van Koophandel, KvK) through their official API <https://developers.kvk.nl/>. Search for companies by name, location, or registration number. Retrieve detailed business profiles, establishment information, and company name histories. Built on httr2 for robust API interaction with automatic pagination, error handling, and usage tracking.

Software to aid in modeling and analyzing mass-spectrometry-based proteome melting data. Quantitative data is imported and normalized and thermal behavior is modeled at the protein level. Methods exist for normalization, modeling, visualization, and export of results. For a general introduction to MS-based thermal profiling, see Savitski et al. (2014) <doi:10.1126/science.1255784>.

The mFilter package implements several time series filters useful for smoothing and extracting trend and cyclical components of a time series. The routines are commonly used in economics and finance, however they should also be interest to other areas. Currently, Christiano-Fitzgerald, Baxter-King, Hodrick-Prescott, Butterworth, and trigonometric regression filters are included in the package.