An implementation of 14 parsimonious mixture models for model-based clustering or model-based classification. Gaussian, Student's t, generalized hyperbolic, variance-gamma or skew-t mixtures are available. All approaches work with missing data. Celeux and Govaert (1995) <doi:10.1016/0031-3203(94)00125-6>, Browne and McNicholas (2014) <doi:10.1007/s11634-013-0139-1>, Browne and McNicholas (2015) <doi:10.1002/cjs.11246>.

Format numbers and plots for publication; includes the removal of leading zeros, standardization of number of digits, addition of affixes, and a p-value formatter. These tools combine the functionality of several base functions such as paste()', format()', and sprintf() into specific use case functions that are named in a way that is consistent with usage, making their names easy to remember and easy to deploy.

Simulate DNA sequences for the node substitution model. In the node substitution model, substitutions accumulate additionally during a speciation event, providing a potential mechanistic explanation for substitution rate variation. This package provides tools to simulate such a process, simulate a reference process with only substitutions along the branches, and provides tools to infer phylogenies from alignments. More information can be found in Janzen (2021) <doi:10.1093/sysbio/syab085>.

Likelihood based optimal partitioning and indicator species analysis. Finding the best binary partition for each species based on model selection, with the possibility to take into account modifying/confounding variables as described in Kemencei et al. (2014) <doi:10.1556/ComEc.15.2014.2.6>. The package implements binary and multi-level response models, various measures of uncertainty, Lorenz-curve based thresholding, with native support for parallel computations.

Complex graphical representations of data are best explored using interactive elements. parcats adds interactive graphing capabilities to the easyalluvial package. The plotly.js parallel categories diagrams offer a good framework for creating interactive flow graphs that allow manual drag and drop sorting of dimensions and categories, highlighting single flows and displaying mouse over information. The plotly.js dependency is quite heavy and therefore is outsourced into a separate package.

Computes nonparametric p-values for the potential class memberships of new observations as well as cross-validated p-values for the training data. The p-values are based on permutation tests applied to an estimated Bayesian likelihood ratio, using a plug-in statistic for the Gaussian model, k nearest neighbors', weighted nearest neighbors or penalized logistic regression'. Additionally, it provides graphical displays and quantitative analyses of the p-values.

The plotcli package provides terminal-based plotting in R. It supports colored scatter plots, line plots, bar plots, boxplots, histograms, density plots, and more. The ggplotcli() function is a universal converter that renders any ggplot2 plot in the terminal using Unicode Braille characters or ASCII. Features include support for 15+ geom types, faceting (facet_wrap/facet_grid), automatic theme detection, legends, optimized color mapping, and multiple canvas types.

Hexadecimal codes are typically used to represent colors in R. Connecting these codes to their colors requires practice or memorization. palette provides a vctrs class for working with color palettes, including printing and plotting functions. The goal of the class is to place visual representations of color palettes directly on or, at least, next to their corresponding character representations. Palette extensions also are provided for data frames using pillar'.

Generates multivariate data with count and continuous variables with a pre-specified correlation matrix. The count and continuous variables are assumed to have Poisson and normal marginals, respectively. The data generation mechanism is a combination of the normal to anything principle and a connection between Poisson and normal correlations in the mixture. The details of the method are explained in Yahav et al. (2012) <DOI:10.1002/asmb.901>.

For a single, known pathogen phylogeny, provides functions for enumeration of the set of compatible epidemic transmission trees, and for uniform sampling from that set. Optional arguments allow for incomplete sampling with a known number of missing individuals, multiple sampling, and known infection time limits. Always assumed are a complete transmission bottleneck and no superinfection or reinfection. See Hall and Colijn (2019) <doi:10.1093/molbev/msz058> for methodology.

Different multiple testing procedures for correlation tests are implemented. These procedures were shown to theoretically control asymptotically the Family Wise Error Rate (Roux (2018) <https://tel.archives-ouvertes.fr/tel-01971574v1>) or the False Discovery Rate (Cai & Liu (2016) <doi:10.1080/01621459.2014.999157>). The package gather four test statistics used in correlation testing, four FWER procedures with either single step or stepdown versions, and four FDR procedures.

Rcpp Bindings for the C code of the Corpus Workbench ('CWB'), an indexing and query engine to efficiently analyze large corpora (<https://cwb.sourceforge.io>). RcppCWB is licensed under the GNU GPL-3, in line with the GPL-3 license of the CWB (<https://www.r-project.org/Licenses/GPL-3>). The CWB relies on pcre2 (BSD license, see <https://github.com/PCRE2Project/pcre2/blob/master/LICENCE.md>) and GLib (LGPL license, see <https://www.gnu.org/licenses/lgpl-3.0.en.html>). See the file LICENSE.note for further information. The package includes modified code of the rcqp package (GPL-2, see <https://cran.r-project.org/package=rcqp>). The original work of the authors of the rcqp package is acknowledged with great respect, and they are listed as authors of this package. To achieve cross-platform portability (including Windows), using Rcpp for wrapper code is the approach used by RcppCWB'.

EpiDISH is a R package to infer the proportions of a priori known cell-types present in a sample representing a mixture of such cell-types. Right now, the package can be used on DNAm data of whole blood, generic epithelial tissue and breast tissue. Besides, the package provides a function that allows the identification of differentially methylated cell-types and their directionality of change in Epigenome-Wide Association Studies.

This package provides a system for embedded scientific computing and reproducible research with R. The OpenCPU server exposes a simple but powerful HTTP API for RPC and data interchange with R. This provides a reliable and scalable foundation for statistical services or building R web applications. The OpenCPU server runs either as a single-user development server within the interactive R session, or as a multi-user stack based on Apache2.

Perform common useful JavaScript operations in Shiny apps that will greatly improve your apps without having to know any JavaScript. Examples include: hiding an element, disabling an input, resetting an input back to its original value, delaying code execution by a few seconds, and many more useful functions for both the end user and the developer. Shinyjs can also be used to easily call your own custom JavaScript functions from R.

This package provides the Open Source Geometry Engine (GEOS) as a C API that can be used to write high-performance C and C++ geometry operations using R as an interface. Headers are provided to make linking to and using these functions from C++ code as easy and as safe as possible. This package contains an internal copy of the GEOS library to guarantee the best possible consistency on multiple platforms.

This package implements various estimators of entropy, such as the shrinkage estimator by Hausser and Strimmer, the maximum likelihood and the Millow-Madow estimator, various Bayesian estimators, and the Chao-Shen estimator. It also offers an R interface to the NSB estimator. Furthermore, it provides functions for estimating Kullback-Leibler divergence, chi-squared, mutual information, and chi-squared statistic of independence. In addition there are functions for discretizing continuous random variables.

This package is a collection of ANSI escape code related libraries enabling ANSI colorization and stylization of console output. Included in the library are the Code module, which defines ANSI codes as constants and methods, a Mixin module for including color methods, a Logger, a ProgressBar, and a String subclass. The library also includes a Terminal module which provides information about the current output device.

This package provides example one-dimensional proton NMR spectra of murine urine samples collected before and after bariatric or sham surgery (Roux-en-Y gastric bypass). The data are adapted from Jia V Li et al. (2011), "Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk", Gut, 60(9), 1214–1223. <doi:10.1136/gut.2010.234708>. This package serves as example data for metabolomics analysis and teaching purposes.

This package provides a model designed for dimensionality reduction and batch effect removal for scRNA-seq data. It is designed to be massively parallelizable using shared objects that prevent memory duplication, and it can be used with different mini-batch approaches in order to reduce time consumption. It assumes a negative binomial distribution for the data with a dispersion parameter that can be both commonwise across gene both genewise.

This package provides functions for identification and visualization of potential intramolecular triplex patterns in DNA sequence. The main functionality is to detect the positions of subsequences capable of folding into an intramolecular triplex (H-DNA) in a much larger sequence. The potential H-DNA (triplexes) should be made of as many cannonical nucleotide triplets as possible. The package includes visualization showing the exact base-pairing in 1D, 2D or 3D.

This package provides functions for downloading data from the Bank for International Settlements (BIS; <https://www.bis.org/>) in Basel. Supported are only full datasets in (typically) CSV format. The package is lightweight and without dependencies; suggested packages are used only if data is to be transformed into particular data structures, for instance into zoo objects. Downloaded data can optionally be cached, to avoid repeated downloads of the same files.

This package provides a fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 <doi:10.1016/j.ajhg.2017.05.015>.

This package implements a specific form of segmented linear regression with two independent variables. The visualization of that function looks like a quarter segment of a cowbell giving the package its name. The package has been specifically constructed for the case where minimum and maximum value of the dependent and two independent variables are known a prior, which is usually the case when those values are derived from Likert scales.