Phone numbers are often represented as strings because there is no obvious and suitable native representation for them. This leads to high memory use and a lack of standard representation. The package provides integer representation of Australian phone numbers with optional raw vector calling code. The package name is an extension of au and ph'.

The main functions are emmreml', and emmremlMultiKernel'. emmreml solves a mixed model with known covariance structure using the EMMA algorithm. emmremlMultiKernel is a wrapper for emmreml to handle multiple random components with known covariance structures. The function emmremlMultivariate solves a multivariate gaussian mixed model with known covariance structure using the ECM algorithm.

We implement a cocktail algorithm, a good mixture of coordinate decent, the majorization-minimization principle and the strong rule, for computing the solution paths of the elastic net penalized Cox's proportional hazards model. The package is an implementation of Yang, Y. and Zou, H. (2013) DOI: <doi:10.4310/SII.2013.v6.n2.a1>.

This package provides tools for efficient processing of large, whole genome genotype data sets in variant call format (VCF). It includes several functions to calculate commonly used population genomic metrics and a method for reference panel free genotype imputation, which is described in the preprint Gurke & Mayer (2024) <doi:10.22541/au.172515591.10119928/v1>.

Dieses R-Paket stellt Zusatzmaterial in Form von Daten, Funktionen und R-Hilfe-Seiten für den Herausgeberband Breit, S. und Schreiner, C. (Hrsg.). (2016). "Large-Scale Assessment mit R: Methodische Grundlagen der österreichischen Bildungsstandardüberprüfung." Wien: facultas. (ISBN: 978-3-7089-1343-8, <https://www.iqs.gv.at/themen/bildungsforschung/publikationen/veroeffentlichte-publikationen>) zur Verfügung.

Compose interactive visualisations designed for exploratory high-dimensional data analysis. With liminal you can create linked interactive graphics to diagnose the quality of a dimension reduction technique and explore the global structure of a dataset with a tour. A complete description of the method is discussed in ['Lee & Laa & Cook (2020) <arXiv:2012.06077>].

This package provides methods and functions to analyze the quantitative or qualitative performance for diagnostic assays, and outliers detection, reader precision and reference range are discussed. Most of the methods and algorithms refer to CLSI (Clinical & Laboratory Standards Institute) recommendations and NMPA (National Medical Products Administration) guidelines. In additional, relevant plots are constructed by ggplot2'.

This package provides functionality to produce graphs of sampling distributions of test statistics from a variety of common statistical tests. With only a few keystrokes, the user can conduct a hypothesis test and visualize the test statistic and corresponding p-value through the shading of its sampling distribution. Initially created for statistics at Middlebury College.

Predicting the structure of a graph including new nodes and edges using a time series of graphs. Flux balance analysis, a linear and integer programming technique used in biochemistry is used with time series prediction methods to predict the graph structure at a future time point Kandanaarachchi (2024) <doi:10.48550/arXiv.2401.04280>.

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the rxode2 package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

The openFDA API facilitates access to Federal Drug Agency (FDA) data on drugs, devices, foodstuffs, tobacco, and more with httr2'. This package makes the API easily accessible, returning objects which the user can convert to JSON data and parse. Kass-Hout TA, Xu Z, Mohebbi M et al. (2016) <doi:10.1093/jamia/ocv153>.

Access a variety of PubMed data through a single, user-friendly interface, including abstracts <https://pubmed.ncbi.nlm.nih.gov/>, bibliometrics from iCite <https://icite.od.nih.gov/>, pubtations from PubTator3 <https://www.ncbi.nlm.nih.gov/research/pubtator3/>, and full-text records from PMC <https://www.ncbi.nlm.nih.gov/pmc/>.

Programs for Martinussen and Scheike (2006), `Dynamic Regression Models for Survival Data', Springer Verlag. Plus more recent developments. Additive survival model, semiparametric proportional odds model, fast cumulative residuals, excess risk models and more. Flexible competing risks regression including GOF-tests. Two-stage frailty modelling. PLS for the additive risk model. Lasso in the ahaz package.

The diffUTR package provides a uniform interface and plotting functions for limma/edgeR/DEXSeq -powered differential bin/exon usage. It includes in addition an improved version of the limma::diffSplice method. Most importantly, diffUTR further extends the application of these frameworks to differential UTR usage analysis using poly-A site databases.

metaCCA performs multivariate analysis of a single or multiple GWAS based on univariate regression coefficients. It allows multivariate representation of both phenotype and genotype. metaCCA extends the statistical technique of canonical correlation analysis to the setting where original individual-level records are not available, and employs a covariance shrinkage algorithm to achieve robustness.

The genome is divided into non-overlapping fixed-sized bins, number of sequence reads in each counted, adjusted with a simultaneous two-dimensional loess correction for sequence mappability and GC content, and filtered to remove spurious regions in the genome. Downstream steps of segmentation and calling are also implemented via packages DNAcopy and CGHcall, respectively.

This package contains various routines for drawing ellipses and ellipse-like confidence regions, implementing the plots described in Murdoch and Chow (1996), A graphical display of large correlation matrices, The American Statistician 50, 178-180. There are also routines implementing the profile plots described in Bates and Watts (1988), Nonlinear Regression Analysis and its Applications.

This package provides a regular expression toolkit for regex-base with compile-time checking of regular expression syntax, data types for matches and captures, a text replacement toolkit, portable options, high-level AWK-like tools for building text processing apps, regular expression macros with parsers and test bench, comprehensive documentation, tutorials and copious examples.

The 6581 SID chip is the sound chip used in the Commodore 64 computer. reMID is a MIDI implementation of the 6581 SID chip using the reSID library to provide a virtual SID-based synthesizer, controllable in real-time via MIDI. It includes support for scripted instruments that allow complex sonic control of the chip.

This package implements a general framework for finite mixtures of regression models using the EM algorithm. FlexMix provides the E-step and all data handling, while the M-step can be supplied by the user to easily define new models. Existing drivers implement mixtures of standard linear models, generalized linear models and model-based clustering.

Processes standard recommendation datasets (e.g., a user-item rating matrix) as input and generates rating predictions and lists of recommended items. Standard algorithm implementations which are included in this package are the following: Global/Item/User-Average baselines, Weighted Slope One, Item-Based KNN, User-Based KNN, FunkSVD, BPR and weighted ALS. They can be assessed according to the standard offline evaluation methodology (Shani, et al. (2011) <doi:10.1007/978-0-387-85820-3_8>) for recommender systems using measures such as MAE, RMSE, Precision, Recall, F1, AUC, NDCG, RankScore and coverage measures. The package (Coba, et al.(2017) <doi: 10.1007/978-3-319-60042-0_36>) is intended for rapid prototyping of recommendation algorithms and education purposes.

Plots simulation results of clinical trials. Its main feature is allowing users to simultaneously investigate the impact of several simulation input dimensions through dynamic filtering of the simulation results. A more detailed description of the app can be found in Meyer et al. <DOI:10.1016/j.softx.2023.101347> or the vignettes on GitHub'.

This package provides functions for data augmentation using the Bayesian discount prior method for single arm and two-arm clinical trials, as described in Haddad et al. (2017) <doi:10.1080/10543406.2017.1300907>. The discount power prior methodology was developed in collaboration with the The Medical Device Innovation Consortium (MDIC) Computer Modeling & Simulation Working Group.

Querying, extracting, and processing large-scale network data from Neo4j databases using the Neo4j Bolt <https://neo4j.com/docs/bolt/current/bolt/> protocol. This interface supports efficient data retrieval, batch processing for large datasets, and seamless conversion of query results into R data frames, making it ideal for bioinformatics, computational biology, and other graph-based applications.