Predicts antimicrobial peptides using random forests trained on the n-gram encoded peptides. The implemented algorithm can be accessed from both the command line and shiny-based GUI. The AmpGram model is too large for CRAN and it has to be downloaded separately from the repository: <https://github.com/michbur/AmpGramModel>.
Best subset glm using information criteria or cross-validation, carried by using leaps algorithm (Furnival and Wilson, 1974) <doi:10.2307/1267601> or complete enumeration (Morgan and Tatar, 1972) <doi:10.1080/00401706.1972.10488918>. Implements PCR and PLS using AIC/BIC. Implements one-standard deviation rule for use with the caret package.
Provide standard tables, listings, and graphs (TLGs) libraries used in clinical trials. This package implements a structure to reformat the data with dunlin', create reporting tables using rtables and tern with standardized input arguments to enable quick generation of standard outputs. In addition, it also provides comprehensive data checks and script generation functionality.
Perform additional multiple testing procedure methods to p.adjust(), such as weighted Hochberg (Tamhane, A. C., & Liu, L., 2008) <doi:10.1093/biomet/asn018>, ICC adjusted Bonferroni method (Shi, Q., Pavey, E. S., & Carter, R. E., 2012) <doi:10.1002/pst.1514> and a new correlation corrected weighted Hochberg for correlated endpoints.
Several nonparametric estimators of autocovariance functions. Procedures for constructing their confidence regions by using bootstrap techniques. Methods to correct autocovariance estimators and several tools for analysing and comparing them. Supplementary functions, including kernel computations and discrete cosine Fourier transforms. For more details see Bilchouris and Olenko (2025) <doi:10.17713/ajs.v54i1.1975>.
Toolkit for processing and calling interactions in capture Hi-C data. Converts BAM files into counts of reads linking restriction fragments, and identifies pairs of fragments that interact more than expected by chance. Significant interactions are identified by comparing the observed read count to the expected background rate from a count regression model.
This package provides a concise check of the format of one or multiple input arguments (data type, length or value) is provided. Since multiple input arguments can be tested simultaneously, a lengthly list of checks at the beginning of your function can be avoided, hereby enhancing the readability and maintainability of your code.
The epilogi variable selection algorithm is implemented for the case of continuous response and predictor variables. The relevant paper is: Lakiotaki K., Papadovasilakis Z., Lagani V., Fafalios S., Charonyktakis P., Tsagris M. and Tsamardinos I. (2023). "Automated machine learning for Genome Wide Association Studies". Bioinformatics, 39(9): btad545. <doi:10.1093/bioinformatics/btad545>.
Biotracers and stomach content analyses are combined in a Bayesian hierarchical model to estimate a probabilistic topology matrix (all trophic link probabilities) and a diet matrix (all diet proportions). The package relies on the JAGS software and the jagsUI package to run a Markov chain Monte Carlo approximation of the different variables.
This package provides a toolkit for calculating forest and canopy structural complexity metrics from terrestrial LiDAR (light detection and ranging). References: Atkins et al. 2018 <doi:10.1111/2041-210X.13061>; Hardiman et al. 2013 <doi:10.3390/f4030537>; Parker et al. 2004 <doi:10.1111/j.0021-8901.2004.00925.x>.
Extra geoms and scales for ggplot2', including geom_cloud(), a Normal density cloud replacement for errorbars; transforms ssqrt_trans and pseudolog10_trans, which are loglike but appropriate for negative data; interp_trans() and warp_trans() which provide scale transforms based on interpolation; and an infix compose operator for scale transforms.
This package provides a ggplot2'-native plotting engine for drawing reproducible beautiful Symbol Nomenclature for Glycans (SNFG) glycan cartoons from glycan structure objects or text notations, with support for batch export, structural highlighting, and deep appearance customization. It follows the SNFG specification described at <https://www.ncbi.nlm.nih.gov/glycans/snfg.html>.
Offers a convenient way to compute parameters in the framework of the theory of vocational choice introduced by J.L. Holland, (1997). A comprehensive summary to this theory of vocational choice is given in Holland, J.L. (1997). Making vocational choices. A theory of vocational personalities and work environments. Lutz, FL: Psychological Assessment.
Method for the calculation of copy numbers and calling of copy number alterations. The algorithm uses coverage data from amplicon sequencing of a sample cohort as input. The method includes significance assessment, correction for multiple testing and does not depend on normal DNA controls. Budczies (2016 Mar 15) <doi:10.18632/oncotarget.7451>.
This package provides a collection of shiny applications for the tesselle packages <https://www.tesselle.org/>. This package provides applications for archaeological data analysis and visualization. These mainly, but not exclusively, include applications for chronological modelling (e.g. matrix seriation, aoristic analysis) and count data analysis (e.g. diversity measures, compositional data analysis).
Linear splines with convenient parametrisations such that (1) coefficients are slopes of consecutive segments or (2) coefficients are slope changes at consecutive knots. Knots can be set manually or at break points of equal-frequency or equal-width intervals covering the range of x'. The implementation follows Greene (2003), chapter 7.2.5.
Outlier detection using leave-one-out kernel density estimates and extreme value theory. The bandwidth for kernel density estimates is computed using persistent homology, a technique in topological data analysis. Using peak-over-threshold method, a generalized Pareto distribution is fitted to the log of leave-one-out kde values to identify outliers.
BEAST2 (<https://www.beast2.org>) is a widely used Bayesian phylogenetic tool, that uses DNA/RNA/protein data and many model priors to create a posterior of jointly estimated phylogenies and parameters. mcbette allows to do a Bayesian model comparison over some site and clock models, using babette (<https://github.com/ropensci/babette/>).
This package performs key functions for MCMC analysis using minimal code - visualizes, manipulates, and summarizes MCMC output. Functions support simple and straightforward subsetting of model parameters within the calls, and produce presentable and publication-ready output. MCMC output may be derived from Bayesian model output fit with Stan, NIMBLE, JAGS, and other software.
Create PostgreSQL statements/scripts from R, optionally executing the SQL statements. Common SQL operations are included, although not every configurable option is available at this time. SQL output is intended to be compliant with PostgreSQL syntax specifications. PostgreSQL documentation is available here <https://www.postgresql.org/docs/current/index.html>.
Download economic and financial time series from public sources, including the St Louis Fed's FRED system, Yahoo Finance, the US Bureau of Labor Statistics, the US Energy Information Administration, the World Bank, Eurostat, the European Central Bank, the Bank of England, the UK's Office of National Statistics, Deutsche Bundesbank, and INSEE.
Forms likelihood-based confidence intervals (LBCIs) for parameters in structural equation modeling, introduced in Cheung and Pesigan (2023) <doi:10.1080/10705511.2023.2183860>. Currently implements the algorithm illustrated by Pek and Wu (2018) <doi:10.1037/met0000163>, and supports the robust LBCI proposed by Falk (2018) <doi:10.1080/10705511.2017.1367254>.
Adds support for R startup configuration via .Renviron.d and .Rprofile.d directories in addition to .Renviron and .Rprofile files. This makes it possible to keep private / secret environment variables separate from other environment variables. It also makes it easier to share specific startup settings by simply copying a file to a directory.
Get started with new projects by dropping a skeleton of a new project into a new or existing directory, initialise git repositories, and create reproducible environments with the renv package. The package allows for dynamically named files, folders, file content, as well as the functionality to drop individual template files into existing projects.