Deep Gaussian mixture models as proposed by Viroli and McLachlan (2019) <doi:10.1007/s11222-017-9793-z> provide a generalization of classical Gaussian mixtures to multiple layers. Each layer contains a set of latent variables that follow a mixture of Gaussian distributions. To avoid overparameterized solutions, dimension reduction is applied at each layer by way of factor models.

This package provides a fluent mini-language for building exposure-response plots (model curves/ribbons, quantile-binned summaries, data strips, and grouped distribution panels) from observed data and a fitted exposure-response model. Designed to be model-agnostic: any model object that implements the er_predict() generic (and, optionally, er_simulate() and er_summary()) can be visualised.

Creation of an input model (fitted distribution) via the frequentist model averaging (FMA) approach and generate random-variates from the distribution specified by "myfit" which is the fitted input model via the FMA approach. See W. X. Jiang and B. L. Nelson (2018), "Better Input Modeling via Model Averaging," Proceedings of the 2018 Winter Simulation Conference, IEEE Press, 1575-1586.

This package performs analysis of variance testing procedures for univariate and multivariate functional data (Cuesta-Albertos and Febrero-Bande (2010) <doi:10.1007/s11749-010-0185-3>, Gorecki and Smaga (2015) <doi:10.1007/s00180-015-0555-0>, Gorecki and Smaga (2017) <doi:10.1080/02664763.2016.1247791>, Zhang et al. (2018) <doi:10.1016/j.csda.2018.05.004>).

Implementation of the fast univariate inference approach (Cui et al. (2022) <doi:10.1080/10618600.2021.1950006>, Loewinger et al. (2024) <doi:10.7554/eLife.95802.2>, Xin et al. (2025) <doi:10.7554/eLife.109428.1>) for fitting functional mixed models. User guides and Python package information can be found at <https://github.com/gloewing/photometry_FLMM>.

Fast estimation algorithms to implement the Quantile Regression with Selection estimator and the multiplicative Bootstrap for inference. This estimator can be used to estimate models that feature sample selection and heterogeneous effects in cross-sectional data. For more details, see Arellano and Bonhomme (2017) <doi:10.3982/ECTA14030> and Pereda-Fernández (2024) <doi:10.48550/arXiv.2402.16693>.

Implementation of dynamic principal component analysis (DPCA), simulation of VAR and VMA processes and frequency domain tools. These frequency domain methods for dimensionality reduction of multivariate time series were introduced by David Brillinger in his book Time Series (1974). We follow implementation guidelines as described in Hormann, Kidzinski and Hallin (2016), Dynamic Functional Principal Component <doi:10.1111/rssb.12076>.

Identifying spatially variable genes is critical in linking molecular cell functions with tissue phenotypes. This package implemented a granularity-based dimension-agnostic tool for the identification of spatially variable genes. The detailed description of this method is available at Wang, J. and Li, J. et al. 2023 (Wang, J. and Li, J. (2023), <doi:10.1038/s41467-023-43256-5>).

The IDetect provides efficient implementation of the ID methodology for the consistent estimation of the number and location of multiple change-points in one-dimensional data sequences from the `deterministic + noise model. Currently implemented scenarios are: piecewise-constant signal, piecewise-constant signal with a heavy-tailed noise, continuous piecewise-linear signal, continuous piecewise-linear signal with a heavy-tailed noise.

Simulating species migration and range dynamics under stable or changing environmental conditions based on a simple, raster-based, deterministic or stochastic migration model. KISSMig runs on binary or quantitative suitability maps, which are pre-calculated with niche-based habitat suitability models (also called ecological niche models (ENMs) or species distribution models (SDMs)). Nobis & Normand (2014), <doi:10.1111/ecog.00930>.

This package provides a framework for integrating Large Language Models (LLMs) with R programming through workflow automation. Built on the ReAct (Reasoning and Acting) architecture, enables bi-directional communication between LLMs and R environments. Features include automated code generation and execution, intelligent error handling with retry mechanisms, persistent session management, structured JSON output validation, and context-aware conversation management.

This package provides functions to retrieve public data from ORCID (Open Researcher and Contributor ID) records via the ORCID public API. Fetches employment history, education, works (publications, datasets, preprints), funding, peer review activities, and other public information. Returns data as structured data.table objects for easy analysis and manipulation. Replaces the discontinued rorcid package with a modern, CRAN-compliant implementation.

Bland (2009) <doi:10.1136/bmj.b3985> recommended to base study sizes on the width of the confidence interval rather the power of a statistical test. The goal of presize is to provide functions for such precision based sample size calculations. For a given sample size, the functions will return the precision (width of the confidence interval), and vice versa.

This package provides analysis of high-dimensional single-cell splicing data. Offers a framework to extract and work with ratio-based data structures derived from single-cell RNA sequencing experiments. Provides both a modern R6 object-oriented interface and direct matrix manipulation functions. Core functionalities are implemented in C++ via Rcpp to ensure high performance and scalability on large datasets.

Collection of model estimation, and model plotting functions related to the STEPCAM family of community assembly models. STEPCAM is a STEPwise Community Assembly Model that infers the relative contribution of Dispersal Assembly, Habitat Filtering and Limiting Similarity from a dataset consisting of the combination of trait and abundance data. See also <doi:10.1890/14-0454.1> for more information.

Fast calculation of tree rearrangement distances. For unrooted trees: Subtree Prune and Regraft (SPR), Tree Bisection and Reconnection (TBR), and Replug distances, using the algorithms of Whidden and Matsen (2017) <doi:10.48550/arXiv.1511.07529>. For rooted trees: rooted SPR (rSPR) distance, using the fixed-parameter algorithms of Whidden, Beiko, and Zeh (2013) <doi:10.1137/110845045>.

This groundbreaking technical indicator directly integrates volatility into price averaging by weighting median range-bound prices using the True Range. Unlike conventional metrics such as TWAP (Time-Weighted Average Price), which focuses solely on time, or VWAP (Volume-Weighted Average Price), which emphasizes volume, TrueWAP captures fluctuating market behavior by reflecting true price movement within high/low performance boundaries.

This package provides a R interface to the vouch project (<https://github.com/mitchellh/vouch>), which bills itself as "a community trust management system based on explicit vouches to participate". vouch is a Nushell module, so voucher provides a R application programming interface (API) to modify the VOUCHED.td database without Nushell'. voucher does not depend on vouch or Nushell'.

This package generates ROC plots. Most ROC curve plots obscure the cutoff values and inhibit interpretation and comparison of multiple curves. This attempts to address those shortcomings by providing plotting and interactive tools. Functions are provided to generate an interactive ROC curve plot for web use, and print versions. A Shiny application implementing the functions is also included.

Network Security Services (NSS) is a set of libraries designed to support cross-platform development of security-enabled client and server applications. Applications built with NSS can support SSL v2 and v3, TLS, PKCS #5, PKCS #7, PKCS #11, PKCS #12, S/MIME, X.509 v3 certificates, and other security standards.

This package tracks the Rapid Release channel, which updates frequently.

BED files store ranged genomic data that can be queried even when the files are compressed. iscream can query data from BED files and return them in muliple formats: parsed records or their summary statistics as data frames or GenomicRanges objects, and matrices as matrix, GenomicRanges, or SummarizedExperiment objects. iscream also provides specialized support for importing methylation data.

Power and associated functions useful in prospective planning and monitoring of a clinical trial when a recurrent event endpoint is to be assessed by the robust Andersen-Gill model, see Lin, Wei, Yang, and Ying (2010) <doi:10.1111/1467-9868.00259>. The equations developed in Ingel and Jahn-Eimermacher (2014) <doi:10.1002/bimj.201300090> and their consequences are employed.

This package performs requests to the Arctos API to download data. Provides a set of builder classes for performing complex requests, as well as a set of simple functions for automating many common requests and workflows. More information about Arctos can be found in Cicero et al. (2024) <doi:10.1371/journal.pone.0296478> or on their website <https://arctosdb.org/>.

Generation of natural looking noise has many application within simulation, procedural generation, and art, to name a few. The ambient package provides an interface to the FastNoise C++ library and allows for efficient generation of perlin, simplex, worley, cubic, value, and white noise with optional perturbation in either 2, 3, or 4 (in case of simplex and white noise) dimensions.