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Is used to simulate and fit biological geometries. biogeom incorporates several novel universal parametric equations that can generate the profiles of bird eggs, flowers, linear and lanceolate leaves, seeds, starfish, and tree-rings (Gielis (2003) <doi:10.3732/ajb.90.3.333>; Shi et al. (2020) <doi:10.3390/sym12040645>), three growth-rate curves representing the ontogenetic growth trajectories of animals and plants against time, and the axially symmetrical and integral forms of all these functions (Shi et al. (2017) <doi:10.1016/j.ecolmodel.2017.01.012>; Shi et al. (2021) <doi:10.3390/sym13081524>). The optimization method proposed by Nelder and Mead (1965) <doi:10.1093/comjnl/7.4.308> was used to estimate model parameters. biogeom includes several real data sets of the boundary coordinates of natural shapes, including avian eggs, fruit, lanceolate and ovate leaves, tree rings, seeds, and sea stars,and can be potentially applied to other natural shapes. biogeom can quantify the conspecific or interspecific similarity of natural outlines, and provides information with important ecological and evolutionary implications for the growth and form of living organisms. Please see Shi et al. (2022) <doi:10.1111/nyas.14862> for details.
This package provides a GUI to correct measurement bias in DNA methylation analyses. The BiasCorrector package just wraps the functions implemented in the R package rBiasCorrection into a shiny web application in order to make them more easily accessible. Publication: Kapsner et al. (2021) <doi:10.1002/ijc.33681>.
This package provides tools for fitting Bayesian single index models with flexible choices of priors for both the index and the link function. The package implements model estimation and posterior inference using efficient MCMC algorithms built on the nimble framework, allowing users to specify, extend, and simulate models in a unified and reproducible manner. The following methods are implemented in the package: Antoniadis et al. (2004) <https://www.jstor.org/stable/24307224>, Wang (2009) <doi:10.1016/j.csda.2008.12.010>, Choi et al. (2011) <doi:10.1080/10485251003768019>, Dhara et al. (2019) <doi:10.1214/19-BA1170>, McGee et al. (2023) <doi:10.1111/biom.13569>.
Calculates B-value and empirical equivalence bound. B-value is defined as the maximum magnitude of a confidence interval; and the empirical equivalence bound is the minimum B-value at a certain level. A new two-stage procedure for hypothesis testing is proposed, where the first stage is conventional hypothesis testing and the second is an equivalence testing procedure using the introduced empirical equivalence bound. See Zhao et al. (2019) "B-Value and Empirical Equivalence Bound: A New Procedure of Hypothesis Testing" <arXiv:1912.13084> for details.
Exploratory data analysis methods to summarize, visualize and describe datasets. The main principal component methods are available, those with the largest potential in terms of applications: principal component analysis (PCA) when variables are quantitative, correspondence analysis (CA) when variables are categorical, Multiple Factor Analysis (MFA) when variables are structured in groups.
Bayesian Additive Regression Kernels (BARK) provides an implementation for non-parametric function estimation using Levy Random Field priors for functions that may be represented as a sum of additive multivariate kernels. Kernels are located at every data point as in Support Vector Machines, however, coefficients may be heavily shrunk to zero under the Cauchy process prior, or even, set to zero. The number of active features is controlled by priors on precision parameters within the kernels, permitting feature selection. For more details see Ouyang, Z (2008) "Bayesian Additive Regression Kernels", Duke University. PhD dissertation, Chapter 3 and Wolpert, R. L, Clyde, M.A, and Tu, C. (2011) "Stochastic Expansions with Continuous Dictionaries Levy Adaptive Regression Kernels, Annals of Statistics Vol (39) pages 1916-1962 <doi:10.1214/11-AOS889>.
Nowcasting right-truncated epidemiological data is critical for timely public health decision-making, as reporting delays can create misleading impressions of declining trends in recent data. This package provides nowcasting methods based on using empirical delay distributions and uncertainty from past performance. It is also designed to be used as a baseline method for developers of new nowcasting methods. For more details on the performance of the method(s) in this package applied to case studies of COVID-19 and norovirus, see our recent paper at <https://wellcomeopenresearch.org/articles/10-614>. The package supports standard data frame inputs with reference date, report date, and count columns, as well as the direct use of reporting triangles, and is compatible with epinowcast objects. Alongside an opinionated default workflow, it has a low-level pipe-friendly modular interface, allowing context-specific workflows. It can accommodate a wide spectrum of reporting schedules, including mixed patterns of reference and reporting (daily-weekly, weekly-daily). It also supports sharing delay distributions and uncertainty estimates between strata, as well as custom uncertainty models and delay estimation methods.
Static code analysis of box modules. The package enhances code quality by providing linters that check for common issues, enforce best practices, and ensure consistent coding standards.
An implementation of Bayesian survival models with graph-structured selection priors for sparse identification of omics features predictive of survival (Madjar et al., 2021 <doi:10.1186/s12859-021-04483-z>) and its extension to use a fixed graph via a Markov Random Field (MRF) prior for capturing known structure of omics features, e.g. disease-specific pathways from the Kyoto Encyclopedia of Genes and Genomes database (Hermansen et al., 2025 <doi:10.48550/arXiv.2503.13078>).
This package provides a beginners toolbox to help those in ecology who want to deepen their understanding or utilize Bioacoustics in their work. The package has a number of utilizations from calculating frequency from waveform, performing operations in dB, and determining acoustic range of recorders. The majority of this package is based on key concepts learned from the K. Lisa Yang Center for Conservation Bioacoustics at Cornell University and their associated course: Introduction to Bioacoustics course. More information can be found within the walk through vignettes at <https://github.com/MattyD797/bioSNR/tree/main/vignettes>.
This package creates an interactive graphics interface to visualize backtest results of different financial instruments, such as equities, futures, and credit default swaps. The package does not run backtests on the given data set but displays a graphical explanation of the backtest results. Users can look at backtest graphics for different instruments, investment strategies, and portfolios. Summary statistics of different portfolio holdings are shown in the left panel, and interactive plots of profit and loss (P&L), net market value (NMV) and gross market value (GMV) are displayed in the right panel.
This package provides functions and data sets reproducing some examples in Box, Hunter and Hunter II. Useful for statistical design of experiments, especially factorial experiments.
All the seeds do not germinate at a single point in time due to physiological mechanisms determined by temperature which vary among individual seeds in the population. Seeds germinate by following accumulation of thermal time in degree days/hours, quantified by multiplying the time of germination with excess of base temperature required by each seed for its germination, which follows log-normal distribution. The theoretical germination course can be obtained by regressing the rate of germination at various fractions against temperature (Garcia et al., 1982), where the fraction-wise regression lines intersect the temperature axis at base temperature and the methodology of determining optimum base temperature has been described by Ellis et al. (1987). This package helps to find the base temperature of seed germination using algorithms of Garcia et al. (1982) and Ellis et al. (1982) <doi:10.1093/JXB/38.6.1033> <doi:10.1093/jxb/33.2.288>.
Biologically Explainable Machine Learning Framework for Phenotype Prediction using omics data described in Chen and Schwarz (2017) <doi:10.48550/arXiv.1712.00336>.Identifying reproducible and interpretable biological patterns from high-dimensional omics data is a critical factor in understanding the risk mechanism of complex disease. As such, explainable machine learning can offer biological insight in addition to personalized risk scoring.In this process, a feature space of biological pathways will be generated, and the feature space can also be subsequently analyzed using WGCNA (Described in Horvath and Zhang (2005) <doi:10.2202/1544-6115.1128> and Langfelder and Horvath (2008) <doi:10.1186/1471-2105-9-559> ) methods.
Bell regression models for count data with overdispersion. The implemented models account for ordinary and zero-inflated regression models under both frequentist and Bayesian approaches. Theoretical details regarding the models implemented in the package can be found in Castellares et al. (2018) <doi:10.1016/j.apm.2017.12.014> and Lemonte et al. (2020) <doi:10.1080/02664763.2019.1636940>.
Interface to a high-performance implementation of k-medoids clustering described in Tiwari, Zhang, Mayclin, Thrun, Piech and Shomorony (2020) "BanditPAM: Almost Linear Time k-medoids Clustering via Multi-Armed Bandits" <https://proceedings.neurips.cc/paper/2020/file/73b817090081cef1bca77232f4532c5d-Paper.pdf>.
Implementation of the BRIk, FABRIk and FDEBRIk algorithms to initialise k-means. These methods are intended for the clustering of multivariate and functional data, respectively. They make use of the Modified Band Depth and bootstrap to identify appropriate initial seeds for k-means, which are proven to be better options than many techniques in the literature. Torrente and Romo (2021) <doi:10.1007/s00357-020-09372-3> It makes use of the functions kma and kma.similarity, from the archived package fdakma, by Alice Parodi et al.
This package provides computational tools to generate efficient blocked and unblocked fractional factorial designs for two-level and three-level factors using the generalized Minimum Aberration (MA) criterion and related optimization algorithms. Methodological foundations include the general theory of minimum aberration as described by Cheng and Tang (2005) <doi:10.1214/009053604000001228>, and the catalogue of three-level regular fractional factorial designs developed by Xu (2005) <doi:10.1007/s00184-005-0408-x>. The main functions dol2() and dol3() generate blocked two-level and three-level fractional factorial designs, respectively, using beam search, optimization-based ranking, confounding assessment, and structured output suitable for complete factorial situations.
This package provides tools for the calculation of common biodiversity indices from count data. Additionally, it incorporates bootstrapping techniques to generate multiple samples, facilitating the estimation of confidence intervals around these indices. Furthermore, the package allows for the exploration of how variation in these indices changes with differing numbers of sites, making it a useful tool with which to begin an ecological analysis. Methods are based on the following references: Chao et al. (2014) <doi:10.1890/13-0133.1>, Chao and Colwell (2022) <doi:10.1002/9781119902911.ch2>, Hsieh, Ma,` and Chao (2016) <doi:10.1111/2041-210X.12613>.
Calculate robust measures of effect sizes using the bootstrap.
Bayesian analysis for exponential random graph models using advanced computational algorithms. More information can be found at: <https://acaimo.github.io/Bergm/>.
Two practical tests are provided for assessing whether multiple covariates in a treatment group and a matched control group are balanced in observational studies.
This package provides functions and datasets for Jeff Gill: "Bayesian Methods: A Social and Behavioral Sciences Approach". First, Second, and Third Edition. Published by Chapman and Hall/CRC (2002, 2007, 2014) <doi:10.1201/b17888>.
Data files and functions accompanying the book Korner-Nievergelt, Roth, von Felten, Guelat, Almasi, Korner-Nievergelt (2015) "Bayesian Data Analysis in Ecology using R, BUGS and Stan", Elsevier, New York.