The main purpose of this package is to propose a transparent methodological framework to compare bioregionalization methods based on hierarchical and non-hierarchical clustering algorithms (Kreft & Jetz (2010) <doi:10.1111/j.1365-2699.2010.02375.x>) and network algorithms (Lenormand et al. (2019) <doi:10.1002/ece3.4718> and Leroy et al. (2019) <doi:10.1111/jbi.13674>).

Data sets of the Spanish National Forest Inventory <https://www.miteco.gob.es/es/biodiversidad/servicios/banco-datos-naturaleza/informacion-disponible.html> are processed to compute tree metrics and statistics. Function metrics2Vol() controls most of the routines.

This package provides nested sequential Monte Carlo algorithms for performing sequential inference in the Bayesian Mallows model, which is a widely used probability model for rank and preference data. The package implements the SMC2 (Sequential Monte Carlo Squared) algorithm for handling sequentially arriving rankings and pairwise preferences, including support for complete rankings, partial rankings, and pairwise comparisons. The methods are based on Sorensen (2025) <doi:10.1214/25-BA1564>.

When samples contain missing data, are small, or are suspected of bias, estimation of scale reliability may not be trustworthy. A recommended solution for this common problem has been Bayesian model estimation. Bayesian methods rely on user specified information from historical data or researcher intuition to more accurately estimate the parameters. This package provides a user friendly interface for estimating test reliability. Here, reliability is modeled as a beta distributed random variable with shape parameters alpha=true score variance and beta=error variance (Tanzer & Harlow, 2020) <doi:10.1080/00273171.2020.1854082>.

Distributes Gaussian process calculations across nodes in a distributed memory setting, using Rmpi. The bigGP class provides high-level methods for maximum likelihood with normal data, prediction, calculation of uncertainty (i.e., posterior covariance calculations), and simulation of realizations. In addition, bigGP provides an API for basic matrix calculations with distributed covariance matrices, including Cholesky decomposition, back/forwardsolve, crossproduct, and matrix multiplication.

The goal of this method is to identify associations between bacteria and an environmental variable in 16S or other compositional data. The environmental variable is any variable which is measure for each microbiome sample, for example, a butyrate measurement paired with every sample in the data. Microbiome data is compositional, meaning that the total abundance of each sample sums to 1, and this introduces severe statistical distortions. This method takes a Bayesian approach to correcting for these statistical distortions, in which the total abundance is treated as an unknown variable. This package runs the python implementation using reticulate.

Inference on the marginal model of the mixed effect model with the Box-Cox transformation and on the model median differences between treatment groups for longitudinal randomized clinical trials. These statistical methods are proposed by Maruo et al. (2017) <doi:10.1002/sim.7279>.

The bias-corrected estimation methods for the receiver operating characteristics ROC surface and the volume under ROC surfaces (VUS) under missing at random (MAR) assumption.

This package provides tools and code snippets for summarizing nested data, adverse events and REDCap study information.

This package provides functions to fit, via Expectation-Maximization (EM) algorithm, the Bessel and Beta regressions to a data set with a bounded continuous response variable. The Bessel regression is a new and robust approach proposed in the literature. The EM version for the well known Beta regression is another major contribution of this package. See details in the references Barreto-Souza, Mayrink and Simas (2022) <doi:10.1111/anzs.12354> and Barreto-Souza, Mayrink and Simas (2020) <arXiv:2003.05157>.

This package performs a spatial Bayesian general linear model (GLM) for task functional magnetic resonance imaging (fMRI) data on the cortical surface. Additional models include group analysis and inference to detect thresholded areas of activation. Includes direct support for the CIFTI neuroimaging file format. For more information see A. F. Mejia, Y. R. Yue, D. Bolin, F. Lindgren, M. A. Lindquist (2020) <doi:10.1080/01621459.2019.1611582> and D. Spencer, Y. R. Yue, D. Bolin, S. Ryan, A. F. Mejia (2022) <doi:10.1016/j.neuroimage.2022.118908>.

Smoothed lexis diagrams with Bayesian method specifically tailored to cancer incidence data. Providing to calculating slope and constructing credible interval. LC Chien et al. (2015) <doi:10.1080/01621459.2015.1042106>. LH Chien et al. (2017) <doi:10.1002/cam4.1102>.

This package provides functions for training extreme gradient boosting model using propensity score A-learning and weight-learning methods. For further details, see Liu et al. (2024) <doi:10.1093/bioinformatics/btae592>.

Some very simple infrastructure for basis functions.

Bayesian models for accurately estimating conditional distributions by race, using Bayesian Improved Surname Geocoding (BISG) probability estimates of individual race. Implements the methods described in McCartan, Fisher, Goldin, Ho and Imai (2025) <doi:10.1080/01621459.2025.2526695>.

Enables the user to infer potential synthetic lethal relationships by analysing relationships between bimodally distributed gene pairs in big gene expression datasets. Enables the user to visualise these candidate synthetic lethal relationships.

Implementation of multisource exchangeability models for Bayesian analyses of prespecified subgroups arising in the context of basket trial design and monitoring. The R basket package facilitates implementation of the binary, symmetric multi-source exchangeability model (MEM) with posterior inference arising from both exact computation and Markov chain Monte Carlo sampling. Analysis output includes full posterior samples as well as posterior probabilities, highest posterior density (HPD) interval boundaries, effective sample sizes (ESS), mean and median estimations, posterior exchangeability probability matrices, and maximum a posteriori MEMs. In addition to providing "basketwise" analyses, the package includes similar calculations for "clusterwise" analyses for which subgroups are combined into meta-baskets, or clusters, using graphical clustering algorithms that treat the posterior exchangeability probabilities as edge weights. In addition plotting tools are provided to visualize basket and cluster densities as well as their exchangeability. References include Hyman, D.M., Puzanov, I., Subbiah, V., Faris, J.E., Chau, I., Blay, J.Y., Wolf, J., Raje, N.S., Diamond, E.L., Hollebecque, A. and Gervais, R (2015) <doi:10.1056/NEJMoa1502309>; Hobbs, B.P. and Landin, R. (2018) <doi:10.1002/sim.7893>; Hobbs, B.P., Kane, M.J., Hong, D.S. and Landin, R. (2018) <doi:10.1093/annonc/mdy457>; and Kaizer, A.M., Koopmeiners, J.S. and Hobbs, B.P. (2017) <doi:10.1093/biostatistics/kxx031>.

This package contains functions for evaluating, analyzing, and fitting combined action dose response surfaces with the Bivariate Response to Additive Interacting Doses (BRAID) model of combined action, along with tools for implementing other combination analysis methods, including Bliss independence, combination index, and additional response surface methods.

This package provides squared semi partial correlations, tolerance, Mahalanobis, Likelihood Ratio Chi Square, and Pseudo R Square. Aberson, C. L. (2022) <doi:10.31234/osf.io/s2yqn>.

Producing probabilistic projections of net migration rate for all countries of the world or for subnational units using a Bayesian hierarchical model by Azose an Raftery (2015) <doi:10.1007/s13524-015-0415-0>.

Generates robust confidence intervals for standardized regression coefficients using heteroskedasticity-consistent standard errors for models fitted by lm() as described in Dudgeon (2017) <doi:10.1007/s11336-017-9563-z>. The package can also be used to generate confidence intervals for R-squared, adjusted R-squared, and differences of standardized regression coefficients. A description of the package and code examples are presented in Pesigan, Sun, and Cheung (2023) <doi:10.1080/00273171.2023.2201277>.

This package provides functions for modelling microbial inactivation under isothermal or dynamic conditions. The calculations are based on several mathematical models broadly used by the scientific community and industry. Functions enable to make predictions for cases where the kinetic parameters are known. It also implements functions for parameter estimation for isothermal and dynamic conditions. The model fitting capabilities include an Adaptive Monte Carlo method for a Bayesian approach to parameter estimation.

Biostatistical and clinical data analysis, including descriptive statistics, exploratory data analysis, sample size and power calculations, statistical inference, and data visualization. Normality tests are implemented following Mishra et al. (2019) <doi:10.4103/aca.ACA_157_18>, omnibus test procedures are based on Blanca et al. (2017) <doi:10.3758/s13428-017-0918-2> and Field et al. (2012, ISBN:9781446200469), while sample size and power calculation methods follow Chow et al. (2017) <doi:10.1201/9781315183084>.

This package provides a collection of tools for regression analysis of non-negative data, including strictly positive and zero-inflated observations, based on the class of the Box-Cox symmetric (BCS) distributions and its zero-adjusted extension. The BCS distributions are a class of flexible probability models capable of describing different levels of skewness and tail-heaviness. The package offers a comprehensive regression modeling framework, including estimation and tools for evaluating goodness-of-fit.