Facilitates performing matching adjusted indirect comparison (MAIC) analysis where the endpoint of interest is either time-to-event (e.g. overall survival) or binary (e.g. objective tumor response). The method is described by Signorovitch et al (2012) <doi:10.1016/j.jval.2012.05.004>.
Loading NONMEM (NONlinear Mixed-Effect Modeling, <https://www.iconplc.com/solutions/technologies/nonmem/>) and PSN (Perl-speaks-NONMEM, <https://uupharmacometrics.github.io/PsN/>) output files to extract parameter estimates, provide visual predictive check (VPC) and goodness of fit (GOF) plots, and simulate with parameter uncertainty.
Create hexagonal shape sticker image. polaroid can be used in user's web browser. polaroid can be used in shinyapps.io'. In both way, user can download created hexSticker as PNG image. polaroid is built based on argonDash', colourpicker and hexSticker R package.
Helper functions for package creation, building and maintenance. Designed to work with a build system such as GNU make or package fakemake to help you to conditionally work through the stages of package development (such as spell checking, linting, testing, before building and checking a package).
This package provides functions for analysis of network objects, which are imported or simulated by the package. The non-parametric methods of analysis center on snowball and bootstrap sampling for estimating functions of network degree distribution. For other parameters of interest, see, e.g., bootnet package.
This package provides functions for reading and writing Gadget N-body snapshots. The Gadget code is popular in astronomy for running N-body / hydrodynamical cosmological and merger simulations. To find out more about Gadget see the main distribution page at www.mpa-garching.mpg.de/gadget/.
This package provides access to packages developed for downloading, reading and analyzing microdata from household surveys in Integrated System of Household Surveys - SIPD conducted by Brazilian Institute of Geography and Statistics - IBGE. More information can be obtained from the official website <https://www.ibge.gov.br/>.
This package implements the SoftBart model of described by Linero and Yang (2018) <doi:10.1111/rssb.12293>, with the optional use of a sparsity-inducing prior to allow for variable selection. For usability, the package maintains the same style as the BayesTree package.
Type hints are special comments within a function body indicating the intended nature of the function's arguments in terms of data types, dimensions and permitted values. The actual parameters with which the function is called are evaluated against these type hint comments at run-time.
Interactive visualization for Bayesian prior and posterior distributions. This package facilitates an animated transition between prior and posterior distributions. Additionally, it splits the distribution into bars based on the provided breaks, displaying the probability for each region. If no breaks are provided, it defaults to zero.
The synapter package provides functionality to reanalyse label-free proteomics data acquired on a Synapt G2 mass spectrometer. One or several runs, possibly processed with additional ion mobility separation to increase identification accuracy can be combined to other quantitation files to maximise identification and quantitation accuracy.
Splatter is a package for the simulation of single-cell RNA sequencing count data. It provides a simple interface for creating complex simulations that are reproducible and well-documented. Parameters can be estimated from real data and functions are provided for comparing real and simulated datasets.
Subtypes are defined as groups of samples that have distinct molecular and clinical features. Genomic data can be analyzed for discovering patient subtypes, associated with clinical data, especially for survival information. This package is aimed to identify subtypes that are both clinically relevant and biologically meaningful.
Ritornello is a ChIP-seq peak calling algorithm based on signal processing that can accurately call binding events without the need to do a pair total DNA input or IgG control sample. It has been tested for use with narrow binding events such as transcription factor ChIP-seq.
This package provides an estimation and inference methods for models of conditional quantiles: linear and nonlinear parametric and non-parametric models for conditional quantiles of a univariate response and several methods for handling censored survival data. Portfolio selection methods based on expected shortfall risk are also included.
This package performs projection predictive feature selection for generalized linear models and generalized linear and additive multilevel models. The package is compatible with the rstanarm and brms packages, but other reference models can also be used. See the package vignette for more information and examples.
This package constructs basis functions of B-splines, M-splines, I-splines, convex splines (C-splines), periodic splines, natural cubic splines, generalized Bernstein polynomials, their derivatives, and integrals (except C-splines) by closed-form recursive formulas. It also contains a C++ head-only library integrated with Rcpp.
Comprehensive and flexible logging library written in Ruby for use in Ruby programs. It features a hierarchical logging system of any number of levels, custom level names, logger inheritance, multiple output destinations per log event, execution tracing, custom formatting, thread safteyness, XML and YAML configuration, and more.
This package provides functions for (1) computing diagnostic test statistics (sensitivity, specificity, etc.) from confusion matrices with adjustment for various base rates or known prevalence based on McCaffrey et al (2003) <doi:10.1007/978-1-4615-0079-7_1>, (2) computing optimal cut-off scores with different criteria including maximizing sensitivity, maximizing specificity, and maximizing the Youden Index from Youden (1950) <doi:10.1002/1097-0142(1950)3:1%3C32::AID-CNCR2820030106%3E3.0.CO;2-3>, and (3) displaying and comparing classification statistics and area under the receiver operating characteristic (ROC) curves or area under the curves (AUC) across consecutive categories for ordinal variables.
This package provides a customisable set of tools for assessing and grading R or R-markdown scripts from students. It allows for checking correctness of code output, runtime statistics and static code analysis. The latter feature is made possible by representing R expressions using a tree structure.
This package provides functions to efficiently query ArcGIS REST APIs <https://developers.arcgis.com/rest/>. Both spatial and SQL queries can be used to retrieve data. Simple Feature (sf) objects are utilized to perform spatial queries. This package was neither produced nor is maintained by Esri.
This package provides a collection of efficient functions for working with individual ages and corresponding intervals. These include functions for conversion from an age to an interval, aggregation of ages with associated counts in to intervals and the splitting of interval counts based on specified age distributions.
BRIC-seq is a genome-wide approach for determining RNA stability in mammalian cells. This package provides a series of functions for performing quality check of your BRIC-seq data, calculation of RNA half-life for each transcript and comparison of RNA half-lives between two conditions.
This package creates a common framework for organizing, naming, and gathering population, age, race, and ethnicity data from the Census Bureau. Accesses the API <https://www.census.gov/data/developers/data-sets.html>. Provides tools for adding information to existing data to line up with Census data.