Checks that students have the correct version of R', R packages, RStudio and other dependencies installed, and that the recommended RStudio configuration has been applied.

Facilitates local polynomial regression for state dependent covariates in state-space models. The functionality can also be used from C++ based model builder tools such as Rcpp'/'inline', TMB', or JAGS'.

This package provides a simple set of classes and methods for mapping between scalar intensity values and colors. There is also support for layering maps on top of one another using alpha composition.

Salmonella enterica is a major cause of bacterial food-borne disease worldwide. Serotype identification is the most commonly used typing method to characterize Salmonella isolates. However, experimental serotyping needs great cost on manpower and resources. Recently, we found that the newly incorporated spacer in the clustered regularly interspaced short palindromic repeat (CRISPR) could serve as an effective marker for typing of Salmonella. It was further revealed by Li et. al (2014) <doi:10.1128/JCM.00696-14> that recognized types based on the combination of two newly incorporated spacer in both CRISPR loci showed high accordance with serotypes. Here, we developed an R package CSESA to predict the serotype based on this finding. Considering itâ s time saving and of high accuracy, we recommend to predict the serotypes of unknown Salmonella isolates using CSESA before doing the traditional serotyping.

Connect and pull data from the CJA API, which powers CJA Workspace <https://github.com/AdobeDocs/cja-apis>. The package was developed with the analyst in mind and will continue to be developed with the guiding principles of iterative, repeatable, timely analysis. New features are actively being developed and we value your feedback and contribution to the process.

Estimation, testing and regression modeling of subdistribution functions in competing risks using quantile regressions, as described in Peng and Fine (2009) <DOI:10.1198/jasa.2009.tm08228>.

This package provides a new method for identification of clusters of genomic regions within chromosomes. Primarily, it is used for calling clusters of cis-regulatory elements (COREs). CREAM uses genome-wide maps of genomic regions in the tissue or cell type of interest, such as those generated from chromatin-based assays including DNaseI, ATAC or ChIP-Seq. CREAM considers proximity of the elements within chromosomes of a given sample to identify COREs in the following steps: 1) It identifies window size or the maximum allowed distance between the elements within each CORE, 2) It identifies number of elements which should be clustered as a CORE, 3) It calls COREs, 4) It filters the COREs with lowest order which does not pass the threshold considered in the approach.

Recalibrate risk scores (predicting binary outcomes) to improve clinical utility of risk score using weighted logistic or constrained logistic recalibration methods. Additionally, produces plots to assess the potential for recalibration to improve the clinical utility of a risk model. Methods are described in detail in Mishra, A. (2019) "Methods for Risk Markers that Incorporate Clinical Utility" <http://hdl.handle.net/1773/44068>.

The data and meta data from Statistics Netherlands (<https://www.cbs.nl>) can be browsed and downloaded. The client uses the open data API of Statistics Netherlands.

This package provides an interactive shiny web application for constructing, analyzing, and visualizing composite indices from multidimensional datasets. Users can upload or select indicator data, group variables into logical categories, apply normalization and weighting methods (such as equal or custom schemes), and compute aggregate composite indices. The shiny interface includes tools for exploring results through tables, plots, and data exports, making it useful for researchers, policymakers, and analysts interested in index-based evaluations.

Finds the most likely originating tissue(s) and developmental stage(s) of tissue-specific RNA sequencing data. The package identifies both pure transcriptomes and mixtures of transcriptomes. The most likely identity is found through comparisons of the sequencing data with high-throughput in situ hybridisation patterns. Typical uses are the identification of cancer cell origins, validation of cell culture strain identities, validation of single-cell transcriptomes, and validation of identity and purity of flow-sorting and dissection sequencing products.

Expands the connector <https://github.com/NovoNordisk-OpenSource/connector> package and provides a convenient interface for accessing and interacting with Databricks <https://www.databricks.com> volumes and tables directly from R.

Tests convergence in macro-financial panels combining Dynamic Factor Models (DFM) and mean-reverting Ornstein-Uhlenbeck (OU) processes. Provides: (i) static/approximate DFMs for large panels with VAR/VECM stability checks, Portmanteau tests and rolling out-of-sample R^2, following Stock and Watson (2002) <doi:10.1198/073500102317351921> and the Generalized Dynamic Factor Model of Forni, Hallin, Lippi and Reichlin (2000) <doi:10.1162/003465300559037>; (ii) cointegration analysis à la Johansen (1988) <doi:10.1016/0165-1889(88)90041-3>; (iii) OU-based convergence and half-life summaries grounded in Uhlenbeck and Ornstein (1930) <doi:10.1103/PhysRev.36.823> and Vasicek (1977) <doi:10.1016/0304-405X(77)90016-2>; (iv) robust inference via sandwich HC/HAC estimators (Zeileis (2004) <doi:10.18637/jss.v011.i10>) and regression diagnostics ('lmtest'); and (v) optional PLS-based factor preselection (Mevik and Wehrens (2007) <doi:10.18637/jss.v018.i02>). Functions emphasize reproducibility and clear, publication-ready summaries.

This package provides a local haplotyping visualization toolbox to capture major patterns of co-inheritance between clusters of linked variants, whilst connecting findings to phenotypic and demographic traits across individuals. crosshap enables users to explore and understand genomic variation across a trait-associated region. For an example of successful local haplotype analysis, see Marsh et al. (2022) <doi:10.1007/s00122-022-04045-8>.

CHAP-GWAS (Chromosomal Haplotype-Integrated Genome-Wide Association Study) provides a dynamically adaptive framework for genome-wide association studies (GWAS) that integrates chromosome-scale haplotypes with single nucleotide polymorphism (SNP) analysis. The method identifies and extends haplotype variants based on their phenotypic associations rather than predefined linkage blocks, enabling high-resolution detection of quantitative trait loci (QTL). By leveraging long-range phased haplotype information, CHAP-GWAS improves statistical power and offers a more comprehensive view of the genetic architecture underlying complex traits.

This package contains functions for testing for significant differences between multiple coefficients of variation. Includes Feltz and Miller's (1996) <DOI:10.1002/(SICI)1097-0258(19960330)15:6%3C647::AID-SIM184%3E3.0.CO;2-P> asymptotic test and Krishnamoorthy and Lee's (2014) <DOI:10.1007/s00180-013-0445-2> modified signed-likelihood ratio test. See the vignette for more, including full details of citations.

Useful libraries for building a Java based GUI under R are provided.

This package implements the regression approach of Zuber and Strimmer (2011) "High-dimensional regression and variable selection using CAR scores" SAGMB 10: 34, <DOI:10.2202/1544-6115.1730>. CAR scores measure the correlation between the response and the Mahalanobis-decorrelated predictors. The squared CAR score is a natural measure of variable importance and provides a canonical ordering of variables. This package provides functions for estimating CAR scores, for variable selection using CAR scores, and for estimating corresponding regression coefficients. Both shrinkage as well as empirical estimators are available.

Iterate and repel visually similar colors away in various ggplot2 plots. When many groups are plotted at the same time on multiple axes, for instance stacked bars or scatter plots, effectively ordering colors becomes difficult. This tool iterates through color combinations to find the best solution to maximize visual distinctness of nearby groups, so plots are more friendly toward colorblind users. This is achieved by two distance measurements, distance between groups within the plot, and CIELAB color space distances between colors as described in Carter et al., (2018) <doi:10.25039/TR.015.2018>.

Generate and analyse crossover designs from combinatorial or search algorithms as well as from literature and a GUI to access them.

R interface for RAPIDS cuML (<https://github.com/rapidsai/cuml>), a suite of GPU-accelerated machine learning libraries powered by CUDA (<https://en.wikipedia.org/wiki/CUDA>).

An interface to the cycle routing/data services provided by CycleStreets', a not-for-profit social enterprise and advocacy organisation. The application programming interfaces (APIs) provided by CycleStreets are documented at (<https://www.cyclestreets.net/api/>). The focus of this package is the journey planning API, which aims to emulate the routes taken by a knowledgeable cyclist. An innovative feature of the routing service of its provision of fastest, quietest and balanced profiles. These represent routes taken to minimise time, avoid traffic and compromise between the two, respectively.

Perform evaluation of automatic subject indexing methods. The main focus of the package is to enable efficient computation of set retrieval and ranked retrieval metrics across multiple dimensions of a dataset, e.g. document strata or subsets of the label set. The package also provides the possibility of computing bootstrap confidence intervals for all major metrics, with seamless integration of parallel computation and propensity scored variants of standard metrics.

Estimation of changepoints using an "S-curve" approximation. Formation of confidence intervals for changepoint locations and magnitudes. Both abrupt and gradual changes can be modeled.