Every research team have their own script for calculation of hemodynamic indexes. This package makes it possible to insert a long-format dataframe, and add both periods of interest (trigger-periods), and delete artifacts with deleter-files.

This package provides a collection of tools to easily analyze clinical data, including functions for correlation analysis, and statistical testing. The package facilitates the integration of clinical metadata with other omics layers, enabling exploration of quantitative variables. It also includes the utility for frequency matching samples across a dataset based on patient variables.

Convert MacArthur-Bates Communicative Development Inventory Words and Gestures scores to would-be scores on Words and Sentences, based on modeling from the Stanford Wordbank <https://wordbank.stanford.edu/>. See Day et al. (2025) <doi:10.1111/desc.70036>.

This package provides functions to calculate weights, estimates of changes and corresponding variance estimates for panel data with non-response. Partially overlapping samples are handled. Initially, weights are calculated by linear calibration. By default, the survey package is used for this purpose. It is also possible to use ReGenesees', which can be installed from <https://github.com/DiegoZardetto/ReGenesees>. Variances of linear combinations (changes and averages) and ratios are calculated from a covariance matrix based on residuals according to the calibration model. The methodology was presented at the conference, The Use of R in Official Statistics, and is described in Langsrud (2016) <http://www.revistadestatistica.ro/wp-content/uploads/2016/06/RRS2_2016_A021.pdf>.

The cystiSim package provides an agent-based model for Taenia solium transmission and control. cystiSim was developed within the framework of CYSTINET, the European Network on taeniosis/cysticercosis, COST ACTION TD1302.

Toolkit for processing and calling interactions in capture Hi-C data. Converts BAM files into counts of reads linking restriction fragments, and identifies pairs of fragments that interact more than expected by chance. Significant interactions are identified by comparing the observed read count to the expected background rate from a count regression model.

Provided R functions for working with the Conditional Negative Binomial distribution.

This package provides SPSS'- and SAS'-like output for cross tabulations of two categorical variables (CROSSTABS) and for hierarchical loglinear analyses of two or more categorical variables (LOGLINEAR). The methods are described in Agresti (2013, ISBN:978-0-470-46363-5), Ajzen & Walker (2021, ISBN:9780429330308), Field (2018, ISBN:9781526440273), Norusis (2012, ISBN:978-0-321-74843-0), Nussbaum (2015, ISBN:978-1-84872-603-1), Stevens (2009, ISBN:978-0-8058-5903-4), Tabachnik & Fidell (2019, ISBN:9780134790541), and von Eye & Mun (2013, ISBN:978-1-118-14640-8).

Includes functions for the analysis of circular data using distributions based on Nonnegative Trigonometric Sums (NNTS). The package includes functions for calculation of densities and distributions, for the estimation of parameters, for plotting and more.

The nonparametric methods for estimating copula entropy, transfer entropy, and the statistics for multivariate normality test and two-sample test are implemented. The methods for estimating transfer entropy and the statistics for multivariate normality test and two-sample test are based on the method for estimating copula entropy. The method for change point detection with copula entropy based two-sample test is also implemented. Please refer to Ma and Sun (2011) <doi:10.1016/S1007-0214(11)70008-6>, Ma (2019) <doi:10.48550/arXiv.1910.04375>, Ma (2022) <doi:10.48550/arXiv.2206.05956>, Ma (2023) <doi:10.48550/arXiv.2307.07247>, and Ma (2024) <doi:10.48550/arXiv.2403.07892> for more information.

Simulates clinical trials and summarizes causal effects and treatment policy estimands in the presence of intercurrent events in a transparent and intuitive manner.

This package provides tools for the fitting and cross validation of exact conditional logistic regression models with lasso and elastic net penalties. Uses cyclic coordinate descent and warm starts to compute the entire path efficiently.

Simulate species occurrence and abundances (counts) along gradients.

This package provides a tool that imports, subsets, visualizes, and exports the Correlates of State Policy Project dataset assembled by Marty P. Jordan and Matt Grossmann (2020) <http://ippsr.msu.edu/public-policy/correlates-state-policy>. The Correlates data contains over 2000 variables across more than 100 years that pertain to state politics and policy in the United States. Users with only a basic understanding of R can subset this data across multiple dimensions, export their search results, create map visualizations, export the citations associated with their searches, and more.

Tool to assessing whether the results of a study could be influenced by collinearity. Simulations under a given hypothesized truth regarding effects of an exposure on the outcome are used and the resulting curves of lagged effects are visualized. A user's manual is provided, which includes detailed examples (e.g. a cohort study looking for windows of vulnerability to air pollution, a time series study examining the linear association of air pollution with hospital admissions, and a time series study examining the non-linear association between temperature and mortality). The methods are described in Basagana and Barrera-Gomez (2021) <doi:10.1093/ije/dyab179>.

This package performs biomedical named entity recognition, Unified Medical Language System (UMLS) concept mapping, and negation detection using the Python spaCy', scispaCy', and medspaCy packages, and transforms extracted data into a wide format for inclusion in machine learning models. The development of the scispaCy package is described by Neumann (2019) <doi:10.18653/v1/W19-5034>. The medspacy package uses ConText', an algorithm for determining the context of clinical statements described by Harkema (2009) <doi:10.1016/j.jbi.2009.05.002>. Clinspacy also supports entity embeddings from scispaCy and UMLS cui2vec concept embeddings developed by Beam (2018) <arXiv:1804.01486>.

Implementation of a probabilistic method for biclustering adapted to overdispersed count data. It is a Gamma-Poisson Latent Block Model. It also implements two selection criteria in order to select the number of biclusters.

Retrieves crypto currency information and historical prices as well as information on the exchanges they are listed on. Historical data contains daily open, high, low and close values for all crypto currencies. All data is scraped from <https://coinmarketcap.com> via their web-api'.

Enumerate orientation-consistent directed networks from an undirected or partially directed skeleton, detect feedback loops, summarize topology, and simulate node dynamics via stochastic differential equations.

Analysis of network community objects with applications to neuroimaging data. There are two main components to this package. The first is the hierarchical multimodal spinglass (HMS) algorithm, which is a novel community detection algorithm specifically tailored to the unique issues within brain connectivity. The other is a suite of semiparametric kernel machine methods that allow for statistical inference to be performed to test for potential associations between these community structures and an outcome of interest (binary or continuous).

This package implements an MCMC algorithm to estimate a hierarchical multinomial logit model with a normal heterogeneity distribution. The algorithm uses a hybrid Gibbs Sampler with a random walk metropolis step for the MNL coefficients for each unit. Dependent variable may be discrete or continuous. Independent variables may be discrete or continuous with optional order constraints. Means of the distribution of heterogeneity can optionally be modeled as a linear function of unit characteristics variables.

This package provides a cookie is a piece of data sent from a web server to a web client which helps in overcoming the statelessness constraint of the HTTP protocol. This package provides the tools to work with them in the form of a cookie parser middleware function, meant to be attached to a bigger R web application, and utilities to write, sign and unsign a cookie. For more details see the Mozilla Developer Network (MDN) web documentation in <https://developer.mozilla.org/en-US/docs/Web/HTTP/Guides/Cookies>.

Mainly used to build tables that are commonly presented for bio-medical/health research, such as basic characteristic tables or descriptive statistics.

This package provides a fast and general implementation of the Elston-Stewart algorithm that can calculate the likelihoods of large and complex pedigrees. References for the Elston-Stewart algorithm are Elston & Stewart (1971) <doi:10.1159/000152448>, Lange & Elston (1975) <doi:10.1159/000152714> and Cannings et al. (1978) <doi:10.2307/1426718>.