This package performs parametric synthesis of sounds with harmonic and noise components such as animal vocalizations or human voice. Also offers tools for audio manipulation and acoustic analysis, including pitch tracking, spectral analysis, audio segmentation, pitch and formant shifting, etc. Includes four interactive web apps for synthesizing and annotating audio, manually correcting pitch contours, and measuring formant frequencies. Reference: Anikin (2019) <doi:10.3758/s13428-018-1095-7>.

This package provides a novel feature-wise normalization method based on a zero-inflated negative binomial model. This method assumes that the effects of sequencing depth vary for each taxon on their mean and also incorporates a rational link of zero probability and taxon dispersion as a function of sequencing depth. Ziyue Wang, Dillon Lloyd, Shanshan Zhao, Alison Motsinger-Reif (2023) <doi:10.1101/2023.10.31.563648>.

This package performs maximum likelihood based estimation and inference on time to event data, possibly subject to non-informative right censoring. FitParaSurv() provides maximum likelihood estimates of model parameters and distributional characteristics, including the mean, median, variance, and restricted mean. CompParaSurv() compares the mean, median, and restricted mean survival experiences of two treatment groups. Candidate distributions include the exponential, gamma, generalized gamma, log-normal, and Weibull.

This package provides a generic reference Bayesian analysis of unidimensional mixture distributions obtained by a location-scale parameterisation of the model is implemented. The including functions simulate and summarize posterior samples for location-scale mixture models using a weakly informative prior. There is no need to define priors for scale-location parameters except two hyperparameters in which are associated with a Dirichlet prior for weights and a simplex.

MsImpute is a package for imputation of peptide intensity in proteomics experiments. It additionally contains tools for MAR/MNAR diagnosis and assessment of distortions to the probability distribution of the data post imputation. The missing values are imputed by low-rank approximation of the underlying data matrix if they are MAR (method = "v2"), by Barycenter approach if missingness is MNAR ("v2-mnar"), or by Peptide Identity Propagation (PIP).

This package provides next-generation sequencing (NGS) and mass spectrometry (MS) sample data, code snippets and replication material used for developing NestLink. The NestLink approach is a protein binder selection and identification technology able to biophysically characterize thousands of library members at once without handling individual clones at any stage of the process. Data were acquired on NGS and MS platforms at the Functional Genomics Center Zurich.

srnadiff is a package that finds differently expressed regions from RNA-seq data at base-resolution level without relying on existing annotation. To do so, the package implements the identify-then-annotate methodology that builds on the idea of combining two pipelines approachs differential expressed regions detection and differential expression quantification. It reads BAM files as input, and outputs a list differentially regions, together with the adjusted p-values.

Nonparametric data-driven approach to discovering heterogeneous subgroups in a selection-on-observables framework. aggTrees allows researchers to assess whether there exists relevant heterogeneity in treatment effects by generating a sequence of optimal groupings, one for each level of granularity. For each grouping, we obtain point estimation and inference about the group average treatment effects. Please reference the use as Di Francesco (2022) <doi:10.2139/ssrn.4304256>.

With appRiori <doi:10.1177/25152459241293110>, users upload the research variables and the app guides them to the best set of comparisons fitting the hypotheses, for both main and interaction effects. Through a graphical explanation and empirical examples on reproducible data, it is shown that it is possible to understand both the logic behind the planned comparisons and the way to interpret them when a model is tested.

Allows the estimation and prediction for binary Gaussian process model. The mean function can be assumed to have time-series structure. The estimation methods for the unknown parameters are based on penalized quasi-likelihood/penalized quasi-partial likelihood and restricted maximum likelihood. The predicted probability and its confidence interval are computed by Metropolis-Hastings algorithm. More details can be seen in Sung et al (2017) <arXiv:1705.02511>.

This package provides a utility to quickly obtain clean and tidy college football data. Serves as a wrapper around the <https://collegefootballdata.com/> API and provides functions to access live play by play and box score data from ESPN <https://www.espn.com> when available. It provides users the capability to access a plethora of endpoints, and supplement that data with additional information (Expected Points Added/Win Probability added).

Network meta-analysis and meta-regression (allows including up to three covariates) for individual participant data, aggregate data, and mixtures of both formats using the three-level hierarchical model. Each format can come from randomized controlled trials or non-randomized studies or mixtures of both. Estimates are generated in a Bayesian framework using JAGS. The implemented models are described by Hamza et al. 2023 <DOI:10.1002/jrsm.1619>.

This package provides some simple functions for printing text in color in markdown or Quarto documents, to be rendered as HTML or LaTeX. This is useful when writing about the use of colors in graphs or tables, where you want to print their names in their actual color to give a direct impression of the color, like â redâ shown in red, or â blueâ shown in blue.

This package provides functions to facilitate the use of the ff package in interaction with big data in SQL databases (e.g. in Oracle', MySQL', PostgreSQL', Hive') by allowing easy importing directly into ffdf objects using DBI', RODBC and RJDBC'. Also contains some basic utility functions to do fast left outer join merging based on match', factorisation of data and a basic function for re-coding vectors.

Read data files readable by gnumeric into R'. Can read whole sheet or a range, from several file formats, including the native format of gnumeric'. Reading is done by using ssconvert (a file converter utility included in the gnumeric distribution <http://www.gnumeric.org>) to convert the requested part to CSV. From gnumeric files (but not other formats) can list sheet names and sheet sizes or read all sheets.

This repository aims to contribute to the econometric models production with Colombian data, by providing a set of web-scrapping functions of some of the main macro-financial indicators. All the sources are public and free, but the advantage of these functions is that they directly download and harmonize the information in R's environment. No need to import or download additional files. You only need an internet connection!

This package provides a suite of functions for the design of case-control and two-phase studies, and the analysis of data that arise from them. Functions in this packages provides Monte Carlo based evaluation of operating characteristics such as powers for estimators of the components of a logistic regression model. For additional detail see: Haneuse S, Saegusa T and Lumley T (2011)<doi:10.18637/jss.v043.i11>.

This package provides tools for Bayesian estimation of meta-analysis models that account for publications bias or p-hacking. For publication bias, this package implements a variant of the p-value based selection model of Hedges (1992) <doi:10.1214/ss/1177011364> with discrete selection probabilities. It also implements the mixture of truncated normals model for p-hacking described in Moss and De Bin (2019) <arXiv:1911.12445>.

This package provides tools for anonymizing sensitive patient and research data. Helps protect privacy while keeping data useful for analysis. Anonymizes IDs, names, dates, locations, and ages while maintaining referential integrity. Methods based on: Sweeney (2002) <doi:10.1142/S0218488502001648>, Dwork et al. (2006) <doi:10.1007/11681878_14>, El Emam et al. (2011) <doi:10.1371/journal.pone.0028071>, Fung et al. (2010) <doi:10.1145/1749603.1749605>.

This package provides tools to compute unbiased pleiotropic heritability estimates of complex diseases from genome-wide association studies (GWAS) summary statistics. We estimate pleiotropic heritability from GWAS summary statistics by estimating the proportion of variance explained from an estimated genetic correlation matrix (Bulik-Sullivan et al. 2015 <doi:10.1038/ng.3406>) and employing a Monte-Carlo bias correction procedure to account for sampling noise in genetic correlation estimates.

Identifies constant, additive, multiplicative, and user-defined simplivariate components in numeric data matrices using a genetic algorithm. Supports flexible pattern definitions and provides visualization for general biclustering applications across diverse domains. The method builds on simplivariate models as introduced in Hageman et al. (2008) <doi:10.1371/journal.pone.0003259> and is related to biclustering frameworks as reviewed by Madeira and Oliveira (2004) <doi:10.1109/TCBB.2004.2>.

Evaluating the biasing impact of geographic features such as airports, cities, roads, rivers in datasets of coordinates based biological collection datasets, by Bayesian estimation of the parameters of a Poisson process. Enables also spatial visualization of sampling bias and includes a set of convenience functions for publication level plotting. Also available as shiny app. The reference for the methodology is: Zizka et al. (2020) <doi:10.1111/ecog.05102>.

Calculate the failure probability of civil engineering problems with Level I up to Level III Methods. Have fun and enjoy. References: Spaethe (1991, ISBN:3-211-82348-4) "Die Sicherheit tragender Baukonstruktionen", AU,BECK (2001) "Estimation of small failure probabilities in high dimensions by subset simulation." <doi:10.1016/S0266-8920(01)00019-4>, Breitung (1989) "Asymptotic approximations for probability integrals." <doi:10.1016/0266-8920(89)90024-6>.

Factor and autoregressive models for matrix and tensor valued time series. We provide functions for estimation, simulation and prediction. The models are discussed in Li et al (2021) <doi:10.48550/arXiv.2110.00928>, Chen et al (2020) <DOI:10.1080/01621459.2021.1912757>, Chen et al (2020) <DOI:10.1016/j.jeconom.2020.07.015>, and Xiao et al (2020) <doi:10.48550/arXiv.2006.02611>.