This package provides a comprehensive data analysis framework for NIH-funded research that streamlines workflows for both data cleaning and preparing NIH Data Archive ('NDA') submission templates. Provides unified access to multiple data sources ('REDCap', MongoDB', Qualtrics') through interfaces to their APIs, with specialized functions for data cleaning, filtering, merging, and parsing. Features automatic validation, field harmonization, and memory-aware processing to enhance reproducibility in multi-site collaborative research as described in Mittal et al. (2021) <doi:10.20900/jpbs.20210011>.

flowGate adds an interactive Shiny app to allow manual GUI-based gating of flow cytometry data in R. Using flowGate, you can draw 1D and 2D span/rectangle gates, quadrant gates, and polygon gates on flow cytometry data by interactively drawing the gates on a plot of your data, rather than by specifying gate coordinates. This package is especially geared toward wet-lab cytometerists looking to take advantage of R for cytometry analysis, without necessarily having a lot of R experience.

Macarron is a workflow for the prioritization of potentially bioactive metabolites from metabolomics experiments. Prioritization integrates strengths of evidences of bioactivity such as covariation with a known metabolite, abundance relative to a known metabolite and association with an environmental or phenotypic indicator of bioactivity. Broadly, the workflow consists of stratified clustering of metabolic spectral features which co-vary in abundance in a condition, transfer of functional annotations, estimation of relative abundance and differential abundance analysis to identify associations between features and phenotype/condition.

This package implements a constrained version of hierarchical agglomerative clustering, in which each observation is associated to a position, and only adjacent clusters can be merged. Typical application fields in bioinformatics include Genome-Wide Association Studies or Hi-C data analysis, where the similarity between items is a decreasing function of their genomic distance. Taking advantage of this feature, the implemented algorithm is time and memory efficient. This algorithm is described in Ambroise et al (2019) <doi:10.1186/s13015-019-0157-4>.

Bayesian networks provide an intuitive framework for probabilistic reasoning and its graphical nature can be interpreted quite clearly. Graph based methods of machine learning are becoming more popular because they offer a richer model of knowledge that can be understood by a human in a graphical format. The bnviewer is an R Package that allows the interactive visualization of Bayesian Networks. The aim of this package is to improve the Bayesian Networks visualization over the basic and static views offered by existing packages.

Supporting the use of the Canadian Community Health Survey (CCHS) by transforming variables from each cycle into harmonized, consistent versions that span survey cycles (currently, 2001 to 2018). CCHS data used in this library is accessed and adapted in accordance to the Statistics Canada Open Licence Agreement. This package uses rec_with_table(), which was developed from sjmisc rec(). Lüdecke D (2018). "sjmisc: Data and Variable Transformation Functions". Journal of Open Source Software, 3(26), 754. <doi:10.21105/joss.00754>.

Designed to create a basic data dictionary and append to the original dataset's attributes list. The package makes use of a tidy dataset and creates a data frame that will serve as a linker that will aid in building the dictionary. The dictionary is then appended to the list of the original dataset's attributes. The user will have the option of entering variable and item descriptions by writing code or use alternate functions that will prompt the user to add these.

This package provides a compositional statistical framework for absolute proportion estimation between fractions in RNA sequencing data. FracFixR addresses the fundamental challenge in fractionated RNA-seq experiments where library preparation and sequencing depth obscure the original proportions of RNA fractions. It reconstructs original fraction proportions using non-negative linear regression, estimates the "lost" unrecoverable fraction, corrects individual transcript frequencies, and performs differential proportion testing between conditions. Supports any RNA fractionation protocol including polysome profiling, sub-cellular localization, and RNA-protein complex isolation.

The IDSL.FSA package was designed to annotate standard .msp (mass spectra format) and .mgf (Mascot generic format) files using mass spectral entropy similarity, dot product (cosine) similarity, and normalized Euclidean mass error (NEME) followed by intelligent pre-filtering steps for rapid spectra searches. IDSL.FSA also provides a number of modules to convert and manipulate .msp and .mgf files. The IDSL.FSA workflow was integrated in the IDSL.CSA and IDSL.NPA packages introduced in <doi:10.1021/acs.analchem.3c00376>.

This package provides a suite of tools for transforming an existing workflow into a self-documenting pipeline with very minimal upfront costs. Segments of the pipeline are specified in much the same way a Make rule is, by declaring an executable recipe (which might be an R script), along with the corresponding targets and dependencies. When the entire pipeline is run through, only those recipes that need to be executed will be. Meanwhile, execution metadata is captured behind the scenes for later inspection.

An innovative tool-set that incorporates graph community detection methods into systematic conservation planning. It is designed to enhance spatial prioritization by focusing on the protection of areas with high ecological connectivity. Unlike traditional approaches that prioritize individual planning units, priorCON focuses on clusters of features that exhibit strong ecological linkages. The priorCON package is built upon the prioritizr package <doi:10.32614/CRAN.package.prioritizr>, using commercial and open-source exact algorithm solvers that ensure optimal solutions to prioritization problems.

Visualize the partitions of simple decision trees, involving one or two predictors, on the scale of the original data. Provides an intuitive alternative to traditional tree diagrams, by visualizing how a decision tree divides the predictor space in a simple 2D plot alongside the original data. The parttree package supports both classification and regression trees from rpart and partykit', as well as trees produced by popular frontend systems like tidymodels and mlr3'. Visualization methods are provided for both base R graphics and ggplot2'.

This package provides a template system based on AdminLTE3 (<https://adminlte.io/themes/v3/>) theme. Comes with default theme that can be easily customized. Developers can upload modified templates on Github', and users can easily download templates with RStudio project wizard. The key features of the default template include light and dark theme switcher, resizing graphs, synchronizing inputs across sessions, new notification system, fancy progress bars, and card-like flip panels with back sides, as well as various of HTML tool widgets.

This package provides functions for computing split regularized estimators defined in Christidis, Lakshmanan, Smucler and Zamar (2019) <doi:10.48550/arXiv.1712.03561>. The approach fits linear regression models that split the set of covariates into groups. The optimal split of the variables into groups and the regularized estimation of the regression coefficients are performed by minimizing an objective function that encourages sparsity within each group and diversity among them. The estimated coefficients are then pooled together to form the final fit.

Provide data generation and estimation tools for the multivariate scale mixtures of normal presented in Lange and Sinsheimer (1993) <doi:10.2307/1390698>, the multivariate scale mixtures of skew-normal presented in Zeller, Lachos and Vilca (2011) <doi:10.1080/02664760903406504>, the multivariate skew scale mixtures of normal presented in Louredo, Zeller and Ferreira (2021) <doi:10.1007/s13571-021-00257-y> and the multivariate scale mixtures of skew-normal-Cauchy presented in Kahrari et al. (2020) <doi:10.1080/03610918.2020.1804582>.

You only need to type why pie charts are bad on Google to find thousands of articles full of (valid) reasons why other types of charts should be preferred over this one. Therefore, because of the little use due to the reasons already mentioned, making pie charts (and related) in R is not straightforward, so other functions are needed to simplify things. In this R package there are useful functions to make tasty pie charts immediately by exploiting the many cool templates provided.

This package provides a collection of several utility functions related to resolvable and affine resolvable Partially Balanced Incomplete Block Designs (PBIBDs), have been developed. In the class of resolvable designs, affine resolvable designs are said to be optimal, Bailey (1995) <doi:10.2307/2337638>. Here, the package contains three functions to generate and study the characterization properties of these designs. Developed functions are named as PBIBD1(), PBIBD2() and PBIBD3(), in which first two functions are used to generate two new series of affine resolvable PBIBDs and last one is used to generate a new series of resolvable PBIBDs, respectively. In addition, these functions can also be used to generate design parameters (v, b, r and k), canonical efficiency factors, variance factor between associates and average variance factors of the generated designs. Here v is the number of treatments, b (= b1 + b2, in case of non-proper design) is the number of blocks, r is the number of replications and k (= k1 + k2; k1 is the size of b1 and k2 is the size of b2) is the block size.

syntenet can be used to infer synteny networks from whole-genome protein sequences and analyze them. Anchor pairs are detected with the MCScanX algorithm, which was ported to this package with the Rcpp framework for R and C++ integration. Anchor pairs from synteny analyses are treated as an undirected unweighted graph (i.e., a synteny network), and users can perform: i. network clustering; ii. phylogenomic profiling (by identifying which species contain which clusters) and; iii. microsynteny-based phylogeny reconstruction with maximum likelihood.

This package calculates classic and/or bootstrap confidence intervals for many parameters such as the population mean, variance, interquartile range (IQR), median absolute deviation (MAD), skewness, kurtosis, Cramer's V, odds ratio, R-squared, quantiles (including median), proportions, different types of correlation measures, difference in means, quantiles and medians. Many of the classic confidence intervals are described in Smithson, M. (2003, ISBN: 978-0761924999). Bootstrap confidence intervals are calculated with the R package boot. Both one- and two-sided intervals are supported.

This package represents an implementation of functions to optimize ordering of nodes in a dendrogram, without affecting the meaning of the dendrogram. A dendrogram can be sorted based on the average distance of subtrees, or based on the smallest distance value. These sorting methods improve readability and interpretability of tree structure, especially for tasks such as comparison of different distance measures or linkage types and identification of tight clusters and outliers. As a result, it also introduces more meaningful reordering for a coupled heatmap visualization.

Evaluate, fit, and analyze Hill dose response models (Goutelle et al., 2008 <doi:10.1111/j.1472-8206.2008.00633.x>), also sometimes referred to as four-parameter log-logistic models. Includes tools to invert Hill models, select models based on the Akaike information criterion (Akaike, 1974 <doi:10.1109/TAC.1974.1100705>) or Bayesian information criterion (Schwarz, 1978 <https://www.jstor.org/stable/2958889>), and construct bootstrapped confidence intervals both on the Hill model parameters and values derived from the Hill model parameters.

This package provides tools for storing and managing competition results. Competition is understood as a set of games in which players gain some abstract scores. There are two ways for storing results: in long (one row per game-player) and wide (one row per game with fixed amount of players) formats. This package provides functions for creation and conversion between them. Also there are functions for computing their summary and Head-to-Head values for players. They leverage grammar of data manipulation from dplyr'.

The level-dependent cross-validation method is implemented for the selection of thresholding value in wavelet shrinkage. This procedure is implemented by coupling a conventional cross validation with an imputation method due to a limitation of data length, a power of 2. It can be easily applied to classical leave-one-out and k-fold cross validation. Since the procedure is computationally fast, a level-dependent cross validation can be performed for wavelet shrinkage of various data such as a data with correlated errors.

This package provides a modular package for measuring disparity (multidimensional space occupancy). Disparity can be calculated from any matrix defining a multidimensional space. The package provides a set of implemented metrics to measure properties of the space and allows users to provide and test their own metrics. The package also provides functions for looking at disparity in a serial way (e.g. disparity through time) or per groups as well as visualising the results. Finally, this package provides several statistical tests for disparity analysis.