Typical morphological profiling datasets have millions of cells and hundreds of features per cell. When working with this data, you must clean the data, normalize the features to make them comparable across experiments, transform the features, select features based on their quality, and aggregate the single-cell data, if needed. cytominer makes these steps fast and easy. Methods used in practice in the field are discussed in Caicedo (2017) <doi:10.1038/nmeth.4397>. An overview of the field is presented in Caicedo (2016) <doi:10.1016/j.copbio.2016.04.003>.

This package implements cluster-polarization coefficient for measuring distributional polarization in single or multiple dimensions, as well as associated functions. Contains support for hierarchical clustering, k-means, partitioning around medoids, density-based spatial clustering with noise, and manually imposed cluster membership. Mehlhaff (2024) <doi:10.1017/S0003055423001041>.

This package implements a specific form of segmented linear regression with two independent variables. The visualization of that function looks like a quarter segment of a cowbell giving the package its name. The package has been specifically constructed for the case where minimum and maximum value of the dependent and two independent variables are known a prior, which is usually the case when those values are derived from Likert scales.

This package provides a new robust principal component analysis algorithm is implemented that relies upon the Cauchy Distribution. The algorithm is suitable for high dimensional data even if the sample size is less than the number of variables. The methodology is described in this paper: Fayomi A., Pantazis Y., Tsagris M. and Wood A.T.A. (2024). "Cauchy robust principal component analysis with applications to high-dimensional data sets". Statistics and Computing, 34: 26. <doi:10.1007/s11222-023-10328-x>.

This package provides a feasible framework for mutation analysis and reverse transcription polymerase chain reaction (RT-PCR) assay evaluation of COVID-19, including mutation profile visualization, statistics and mutation ratio of each assay. The mutation ratio is conducive to evaluating the coverage of RT-PCR assays in large-sized samples. Mercatelli, D. and Giorgi, F. M. (2020) <doi:10.20944/preprints202004.0529.v1>.

Find the location of the code for an R package based on the package's name or string representation. Checks on CRAN based on information in the URL field or BioConductor and GitHub based on constructing a URL, and verifies all paths via testing for a successful response. This can be useful when automating static code analysis based on a list of package names, and similar tasks.

This package provides an alternative approach to multiple testing by calculating a simultaneous upper confidence bounds for the number of true null hypotheses among any subset of the hypotheses of interest, using the methods of Goeman and Solari (2011) <doi:10.1214/11-STS356>.

Collect marketing data from Campaign Manager using the Windsor.ai API <https://windsor.ai/api-fields/>.

This package provides functions to prepare and filter an origin-destination matrix for thematic flow mapping purposes. This comes after Bahoken, Francoise (2016), Mapping flow matrix a contribution, PhD in Geography - Territorial sciences. See Bahoken (2017) <doi:10.4000/netcom.2565>.

Mines contiguous sequential patterns in text.

Facilitates dynamic exploration of text collections through an intuitive graphical user interface and the power of regular expressions. The package contains 1) a helper function to convert a data frame to a corporaexplorerobject and 2) a Shiny app for fast and flexible exploration of a corporaexplorerobject'. The package also includes demo apps with which one can explore Jane Austen's novels and the State of the Union Addresses (data from the janeaustenr and sotu packages respectively).

It helps in development of a principal component analysis based composite index by assigning weights to variables and combining the weighted variables. For method details see Sendhil, R., Jha, A., Kumar, A. and Singh, S. (2018). <doi:10.1016/j.ecolind.2018.02.053>, and Wu, T. (2021). <doi:10.1016/j.ecolind.2021.108006>.

Generate a candidate code list for the Observational Medical Outcomes Partnership (OMOP) common data model based on string matching. For a given search strategy, a candidate code list will be returned.

This package contains a function, also called cchs', that calculates Estimator III of Borgan et al (2000), <DOI:10.1023/A:1009661900674>. This estimator is for fitting a Cox proportional hazards model to data from a case-cohort study where the subcohort was selected by stratified simple random sampling.

This package provides function declarations and inline function definitions that facilitate communication between R and the Armadillo C++ library for linear algebra and scientific computing. This implementation is detailed in Vargas Sepulveda and Schneider Malamud (2024) <doi:10.1016/j.softx.2025.102087>.

Construct directed graphs of S4 class hierarchies and visualize them. In general, these graphs typically are DAGs (directed acyclic graphs), often simple trees in practice.

Reads demographic data from a variety of public data sources, extracting and harmonizing variables useful for the study of childfree individuals. The identification of childfree individuals and those with other family statuses uses Neal & Neal's (2024) "A Framework for Studying Adults who Neither have Nor Want Children" <doi:10.1177/10664807231198869>; A pre-print is available at <doi:10.31234/osf.io/fa89m>.

Inference with control function methods for nonlinear outcome models when the model is known ('Guo and Small (2016) <arXiv:1602.01051>) and when unknown but semiparametric ('Li and Guo (2021) <arXiv:2010.09922>).

Connect to the California Data Exchange Center (CDEC) Web Service <http://cdec.water.ca.gov/>. CDEC provides a centralized database to store, process, and exchange real-time hydrologic information gathered by various cooperators throughout California. The CDEC Web Service <http://cdec.water.ca.gov/dynamicapp/wsSensorData> provides a data download service for accessing historical records.

Implementation of the d/p/q/r family of functions for a continuous analog to the standard discrete binomial with continuous size parameter and continuous support with x in [0, size + 1], following Ilienko (2013) <arXiv:1303.5990>.

Calculating crude sequence ratio, adjusted sequence ratio and confidence intervals using data mapped to the Observational Medical Outcomes Partnership Common Data Model.

Gives convenient access to publicly available police-recorded open crime data from large cities in the United States that are included in the Crime Open Database <https://osf.io/zyaqn/>.

Cluster analysis of a set of variables. Variables can be quantitative, qualitative or a mixture of both.

Data cleaning functions for classes logical, factor, numeric, character, currency and Date to make data cleaning fast and easy. Relying on very few dependencies, it provides smart guessing, but with user options to override anything if needed.