The Certifiably Optimal RulE ListS (Corels) learner by Angelino et al described in <doi:10.48550/arXiv.1704.01701> provides interpretable decision rules with an optimality guarantee, and is made available to R with this package. See the file AUTHORS for a list of copyright holders and contributors.

This package contains the adaptation of bubblebath from MATLAB', developed by Adam Danz and available through the MATLAB Central File Exchange, and the tools to transform a dataframe of radii and points to plot-able paths.

Retrieves historical versions of clinical trial registry entries from <https://ClinicalTrials.gov>. Package functionality and implementation for v 1.0.0 is documented in Carlisle (2022) <DOI:10.1371/journal.pone.0270909>.

This package provides a simple way to manage application settings by loading configuration values from .env or .ini files. It supports default values, type casting, and environment variable overrides, enabling a clean separation of configuration from code. Ideal for managing credentials, API keys, and deployment-specific settings.

An integrated set of tools for thermodynamic calculations in aqueous geochemistry and geobiochemistry. Functions are provided for writing balanced reactions to form species from user-selected basis species and for calculating the standard molal properties of species and reactions, including the standard Gibbs energy and equilibrium constant. Calculations of the non-equilibrium chemical affinity and equilibrium chemical activity of species can be portrayed on diagrams as a function of temperature, pressure, or activity of basis species; in two dimensions, this gives a maximum affinity or predominance diagram. The diagrams have formatted chemical formulas and axis labels, and water stability limits can be added to Eh-pH, oxygen fugacity- temperature, and other diagrams with a redox variable. The package has been developed to handle common calculations in aqueous geochemistry, such as solubility due to complexation of metal ions, mineral buffers of redox or pH, and changing the basis species across a diagram ("mosaic diagrams"). CHNOSZ also implements a group additivity algorithm for the standard thermodynamic properties of proteins.

Cross-validation methods of regression models that exploit features of various modeling functions to improve speed. Some of the methods implemented in the package are novel, as described in Fox and Monette (2026) <doi:10.18637/jss.v116.i08>, and the package vignettes. For general introductions to cross-validation, see, for example, Gareth James, Daniela Witten, Trevor Hastie, and Robert Tibshirani (2021, ISBN 978-1-0716-1417-4, Secs. 5.1, 5.3), "An Introduction to Statistical Learning with Applications in R, Second Edition", and Trevor Hastie, Robert Tibshirani, and Jerome Friedman (2009, ISBN 978-0-387-84857-0, Sec. 7.10), "The Elements of Statistical Learning, Second Edition".

Create data summaries for quality control, extensive reports for exploring data, as well as publication-ready univariate or bivariate tables in several formats (plain text, HTML,LaTeX, PDF, Word or Excel. Create figures to quickly visualise the distribution of your data (boxplots, barplots, normality-plots, etc.). Display statistics (mean, median, frequencies, incidences, etc.). Perform the appropriate tests (t-test, Analysis of variance, Kruskal-Wallis, Fisher, log-rank, ...) depending on the nature of the described variable (normal, non-normal or qualitative). Summarize genetic data (Single Nucleotide Polymorphisms) data displaying Allele Frequencies and performing Hardy-Weinberg Equilibrium tests among other typical statistics and tests for these kind of data.

Process Digital Cover Photography images of tree canopies to get canopy attributes like Foliage Cover and Leaf Area Index. Detailed description of the methods in Chianucci et al. (2022) <doi:10.1007/s00468-018-1666-3>.

Analyzes spatial transcriptomic data using cells-by-genes and cell location matrices to find gene pairs that coordinate their expression between spatially adjacent cells. It enables quantitative analysis and graphical assessment of these cross-expression patterns. See Sarwar et al. (2025) <doi:10.1101/2024.09.17.613579> and <https://github.com/gillislab/CrossExpression/> for more details.

Markov chain Monte Carlo based inference routines for collapsed latent position cluster models or social networks, which includes searches over the model space (number of clusters in the latent position cluster model). The label switching algorithm used is that of Nobile and Fearnside (2007) <doi:10.1007/s11222-006-9014-7> which relies on the algorithm of Carpaneto and Toth (1980) <doi:10.1145/355873.355883>.

This package implements the CKNNRLD algorithm (Clustering-Based K-Nearest Neighbor Regression for Longitudinal Data) for improving K-Nearest Neighbor ('KNN') regression on longitudinal data through cluster-based partitioning and localized prediction. Offers enhanced computational efficiency and accuracy for high-volume longitudinal datasets. The acronym KNN stands for K-Nearest Neighbor. References: Loeloe MS, Tabatabaei SM, Sefidkar R, Mehrparvar AH, Jambarsang S (2025). "Boosting K-nearest neighbor regression performance for longitudinal data through a novel learning approach." BMC Bioinformatics, 26, 232. <doi:10.1186/s12859-025-06205-1>.

This package provides a native R torch port of the Chatterbox text-to-speech engine <https://github.com/resemble-ai/chatterbox>. Provides speech synthesis with voice cloning; model weights are downloaded from HuggingFace <https://huggingface.co/> via the hfhub package.

Monitor and trace changes in clustering solutions of accumulating datasets at successive time points. The clusters can adopt External and Internal transition at succeeding time points. The External transitions comprise of Survived, Merged, Split, Disappeared, and newly Emerged candidates. In contrast, Internal transition includes changes in location and cohesion of the survived clusters. The package uses MONIC framework developed by Spiliopoulou, Ntoutsi, Theodoridis, and Schult (2006)<doi:10.1145/1150402.1150491> .

This package provides a modeling tool allowing gene selection, reverse engineering, and prediction in cascade networks. Jung, N., Bertrand, F., Bahram, S., Vallat, L., and Maumy-Bertrand, M. (2014) <doi:10.1093/bioinformatics/btt705>.

This package provides a new methodology for linear regression with both curve response and curve regressors, which is described in Cho, Goude, Brossat and Yao (2013) <doi:10.1080/01621459.2012.722900> and (2015) <doi:10.1007/978-3-319-18732-7_3>. The key idea behind this methodology is dimension reduction based on a singular value decomposition in a Hilbert space, which reduces the curve regression problem to several scalar linear regression problems.

Analysis of configuration frequencies for simple and repeated measures, multiple-samples CFA, hierarchical CFA, bootstrap CFA, functional CFA, Kieser-Victor CFA, and Lindner's test using a conventional and an accelerated algorithm.

Extends the did package to improve efficiency and handling of unbalanced panel data. Bellego, Benatia, and Dortet-Bernadet (2024), "The Chained Difference-in-Differences", Journal of Econometrics, <doi:10.1016/j.jeconom.2024.105783>.

Allows users to identify similar cases for qualitative case studies using statistical matching methods.

This package provides a set of functions for counterfactual decomposition (cfdecomp). The functions available in this package decompose differences in an outcome attributable to a mediating variable (or sets of mediating variables) between groups based on counterfactual (causal inference) theory. By using Monte Carlo (MC) integration (simulations based on empirical estimates from multivariable models) we provide added flexibility compared to existing (analytical) approaches, at the cost of computational power or time. The added flexibility means that we can decompose difference between groups in any outcome or and with any mediator (any variable type and distribution). See Sudharsanan & Bijlsma (2019) <doi:10.4054/MPIDR-WP-2019-004> for more information.

Matrix-variate covariance estimation via the Kronecker-core decomposition. Computes the Kronecker and core covariance matrices corresponding to an arbitrary covariance matrix, and provides an empirical Bayes covariance estimator that adaptively shrinks towards the space of separable covariance matrices. For details, see Hoff, McCormack and Zhang (2022) <arXiv:2207.12484> "Core Shrinkage Covariance Estimation for Matrix-variate data".

Extends the functionality of base R lists and provides specialized data structures deque', set', dict', and dict.table', the latter to extend the data.table package.

Fit composite Gaussian process (CGP) models as described in Ba and Joseph (2012) "Composite Gaussian Process Models for Emulating Expensive Functions", Annals of Applied Statistics. The CGP model is capable of approximating complex surfaces that are not second-order stationary. Important functions in this package are CGP, print.CGP, summary.CGP, predict.CGP and plotCGP.

This package provides functions for implementing the novel algorithm CASCORE, which is designed to detect latent community structure in graphs with node covariates. This algorithm can handle models such as the covariate-assisted degree corrected stochastic block model (CADCSBM). CASCORE specifically addresses the disagreement between the community structure inferred from the adjacency information and the community structure inferred from the covariate information. For more detailed information, please refer to the reference paper: Yaofang Hu and Wanjie Wang (2022) <arXiv:2306.15616>. In addition to CASCORE, this package includes several classical community detection algorithms that are compared to CASCORE in our paper. These algorithms are: Spectral Clustering On Ratios-of Eigenvectors (SCORE), normalized PCA, ordinary PCA, network-based clustering, covariates-based clustering and covariate-assisted spectral clustering (CASC). By providing these additional algorithms, the package enables users to compare their performance with CASCORE in community detection tasks.

In many studies across different disciplines, detailed measures of the variables of interest are available. If assumptions can be made regarding the direction of effects between the assessed variables, this has to be considered in the analysis. The functions in this package implement the novel approach CIEE (causal inference using estimating equations; Konigorski et al., 2018, <DOI:10.1002/gepi.22107>) for estimating and testing the direct effect of an exposure variable on a primary outcome, while adjusting for indirect effects of the exposure on the primary outcome through a secondary intermediate outcome and potential factors influencing the secondary outcome. The underlying directed acyclic graph (DAG) of this considered model is described in the vignette. CIEE can be applied to studies in many different fields, and it is implemented here for the analysis of a continuous primary outcome and a time-to-event primary outcome subject to censoring. CIEE uses estimating equations to obtain estimates of the direct effect and robust sandwich standard error estimates. Then, a large-sample Wald-type test statistic is computed for testing the absence of the direct effect. Additionally, standard multiple regression, regression of residuals, and the structural equation modeling approach are implemented for comparison.