Extends traditional random-effects meta-analysis by embedding it within a generalized linear mixed-effects model framework. The package supports covariate adjustment and non-normal responses using aggregate data, and provides likelihood-based inference with computationally efficient likelihood evaluation. The underlying methodology is described in Hanada and Sugimoto (2026) <doi:10.1093/biomtc/ujag148>.

Perform a differential analysis at pathway level based on metabolite quantifications and information on pathway metabolite composition. The method, described in Guilmineau et al (2025) <doi:10.1186/s12859-025-06118-z> is based on a Principal Component Analysis step and on a linear mixed model. Automatic query of metabolic pathways is also implemented.

This package provides a very small package for more convenient use of NaileR'. You provide a data set containing a latent variable you want to understand. It generates a description and an interpretation of this latent variable using a Large Language Model. For perceptual data, it describes the stimuli used in the experiment.

Curated color palettes drawn from India's natural beauty - Himalayan snow, Thar dunes, Kerala backwaters, Andaman reefs, Spiti's cold desert, Kashmir's autumn chinar, and more. Provides discrete and continuous palettes with first-class ggplot2 integration through scale_color_prakriti() and scale_fill_prakriti(), plus base graphics helpers for displaying palettes.

Use the paged media properties in CSS and the JavaScript library paged.js to split the content of an HTML document into discrete pages. Each page can have its page size, page numbers, margin boxes, and running headers, etc. Applications of this package include books, letters, reports, papers, business cards, resumes, and posters.

Fits Bayesian spatio-temporal models and makes predictions on stream networks using the approach by Santos-Fernandez, Edgar, et al. (2022)."Bayesian spatio-temporal models for stream networks". <arXiv:2103.03538>. In these models, spatial dependence is captured using stream distance and flow connectivity, while temporal autocorrelation is modelled using vector autoregression methods.

Population genetics package for designing diagnostic panels. Candidate markers, marker combinations, and different panel sizes are assessed for how well they can predict the source population of known samples. Requires a genotype file of candidate markers in STRUCTURE format. Methods for population cross-validation are described in Jombart (2008) <doi:10.1093/bioinformatics/btn129>.

Constructs cell-type-specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into super-cells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factor-target regulatory relationships. It also provides statistical methods for differential edge analysis.

By adding dependencies to the "Suggests" field of a package's DESCRIPTION file, and then declaring that they are needed within any dependent functionality, it is often possible to significantly reduce the number of "hard" dependencies required by a package. This package provides a minimal way to declare when a suggested package is needed.

Operators and functions provided by base R sometimes lack some features found in other programming languages, such as the ability to concatenate strings using + or to repeat strings using *. This package aims at providing such functionality without breaking existing code, i.e., only statements, that would throw errors in pure base R are patched.

Calculates topic-specific diagnostics (e.g. mean token length, exclusivity) for Latent Dirichlet Allocation and Correlated Topic Models fit using the topicmodels package. For more details, see Chapter 12 in Airoldi et al. (2014, ISBN:9781466504080), pp 262-272 Mimno et al. (2011, ISBN:9781937284114), and Bischof et al. (2014) <arXiv:1206.4631v1>.

Implementation of zero-inflated Poisson models under Bayesian framework using data augmentation as discussed in Chapter 5 of Zhang (2020) <https://hdl.handle.net/10012/16378>. This package is constructed in accommodating four different scenarios: the general scenario, the scenario with measurement error in responses, the external validation scenario, and the internal validation scenario.

Parse GFF and GTF files using C++ classes. The package also provides utilities to read and write GFF3 files. The GFF (General Feature Format) format is a tab-delimited file format for describing genes and other features of DNA, RNA, and protein sequences. GFF files are often used to describe the features of genomes.

GDS files are widely used to represent genotyping or sequence data. The GDSArray package implements the `GDSArray` class to represent nodes in GDS files in a matrix-like representation that allows easy manipulation (e.g., subsetting, mathematical transformation) in _R_. The data remains on disk until needed, so that very large files can be processed.

Analysis of historical non-decimal currencies and value systems that use tripartite or tetrapartite systems such as pounds, shillings, and pence. It introduces new vector classes to represent non-decimal currencies, making them compatible with numeric classes, and provides functions to work with these classes in data frames in the context of double-entry bookkeeping.

Spatial downscaling of coarse grid mapping to fine grid mapping using predictive covariates and a model fitted using the caret package. The original dissever algorithm was published by Malone et al. (2012) <doi:10.1016/j.cageo.2011.08.021>, and extended by Roudier et al. (2017) <doi:10.1016/j.compag.2017.08.021>.

This package provides tools for describing parameters of algorithms in an abstract way. Description can include an id, a description, a domain (range or list of values), and a default value. dynparam can also convert parameter sets to a ParamHelpers format, in order to be able to use dynparam in conjunction with mlrMBO'.

Function to create forest plots. Functions to use posterior samples from Bayesian bivariate meta-analysis model, Bayesian hierarchical summary receiver operating characteristic (HSROC) meta-analysis model or Bayesian latent class (LC) meta-analysis model to create Summary Receiver Operating Characteristic (SROC) plots using methods described by Harbord et al (2007)<doi:10.1093/biostatistics/kxl004>.

An implementation of 1) the tail pairwise dependence matrix (TPDM) as described in Jiang & Cooley (2020) <doi:10.1175/JCLI-D-19-0413.1> 2) the extremal pattern index (EPI) as described in Szemkus & Friederichs ('Spatial patterns and indices for heatwave and droughts over Europe using a decomposition of extremal dependency'; submitted to ASCMO 2023).

Statistical methods and simulation tools for the interpretation of forensic DNA mixtures. The methods implemented are described in Haned et al. (2011) <doi:10.1111/j.1556-4029.2010.01550.x>, Haned et al. (2012) <doi:10.1016/j.fsigen.2012.11.002> and Gill & Haned (2013) <doi:10.1016/j.fsigen.2012.08.008>.

Maximum Likelihood Estimation of Stochastic Frontier Production and Cost Functions. Two specifications are available: the error components specification with time-varying efficiencies (Battese and Coelli, 1992, <doi:10.1007/BF00158774>) and a model specification in which the firm effects are directly influenced by a number of variables (Battese and Coelli, 1995, <doi:10.1007/BF01205442>).

This package contains Probability Mass Functions, Cumulative Mass Functions, Negative Log Likelihood value, parameter estimation and modeling data using Binomial Mixture Distributions (BMD) (Manoj et al (2013) <doi:10.5539/ijsp.v2n2p24>) and Alternate Binomial Distributions (ABD) (Paul (1985) <doi:10.1080/03610928508828990>), also Journal article to use the package(<doi:10.21105/joss.01505>).

Finite candidate-set approximate optimal designs for group testing and related experiments, using convex optimization and equivalence checks. Implements the information matrix and cost structure for the prevalence / sensitivity / specificity model used in Huang and colleagues (2020), as in Chi-Kuang Yeh, Weng Kee Wong, and Julie Zhou (<doi:10.48550/arXiv.2508.08445>).

Takes an R expression and returns a job object with a $stop() method which can be called to terminate the background job. Also provides timeouts and other mechanisms for automatically terminating a background job. The result of the expression is available synchronously via $result or asynchronously with callbacks or through the promises package framework.