An efficient and convenient set of functions to perform differential network estimation through the use of alternating direction method of multipliers optimization with a variety of loss functions.

Implementation of the double/debiased machine learning framework of Chernozhukov et al. (2018) <doi:10.1111/ectj.12097> for partially linear regression models, partially linear instrumental variable regression models, interactive regression models and interactive instrumental variable regression models. DoubleML allows estimation of the nuisance parts in these models by machine learning methods and computation of the Neyman orthogonal score functions. DoubleML is built on top of mlr3 and the mlr3 ecosystem. The object-oriented implementation of DoubleML based on the R6 package is very flexible. More information available in the publication in the Journal of Statistical Software: <doi:10.18637/jss.v108.i03>.

This package produces SPSS- and SAS-like output for linear discriminant function analysis and canonical correlation analysis. The methods are described in Manly & Alberto (2017, ISBN:9781498728966), Rencher (2002, ISBN:0-471-41889-7), and Tabachnik & Fidell (2019, ISBN:9780134790541).

This package provides a facility to generate efficient designs for order-of-additions experiments under pair-wise-order model, see Dennis K. J. Lin and Jiayu Peng (2019)."Order-of-addition experiments: A review and some new thoughts". Quality Engineering, 31:1, 49-59, <doi:10.1080/08982112.2018.1548021>. It also provides a facility to generate component orthogonal arrays under component position model, see Jian-Feng Yang, Fasheng Sun & Hongquan Xu (2020): "A Component Position Model, Analysis and Design for Order-of-Addition Experiments". Technometrics, <doi:10.1080/00401706.2020.1764394>.

The automated clustering and quantification of the digital PCR data is based on the combination of DBSCAN (Hahsler et al. (2019) <doi:10.18637/jss.v091.i01>) and c-means (Bezdek et al. (1981) <doi:10.1007/978-1-4757-0450-1>) algorithms. The analysis is independent of multiplexing geometry, dPCR system, and input amount. The details about input data and parameters are available in the vignette.

This package provides methods by Steinhauser et al. (2016) <DOI:10.1186/s12874-016-0196-1> for meta-analysis of diagnostic accuracy studies with several cutpoints.

Includes various functions for playing drum sounds. beat() plays a drum sound from one of the six included drum kits. tempo() sets spacing between calls to beat() in bpm. Together the two functions can be used to create many different drum patterns.

Facilitates the analysis of SNP (single nucleotide polymorphism) and silicodart (presence/absence) data. dartR.popgen provides a suit of functions to analyse such data in a population genetics context. It provides several functions to calculate population genetic metrics and to study population structure. Quite a few functions need additional software to be able to run (gl.run.structure(), gl.blast(), gl.LDNe()). You find detailed description in the help pages how to download and link the packages so the function can run the software. dartR.popgen is part of the the dartRverse suit of packages. Gruber et al. (2018) <doi:10.1111/1755-0998.12745>. Mijangos et al. (2022) <doi:10.1111/2041-210X.13918>.

This package contains functions to perform copula estimation by the non-parametric Bayesian method, Dirichlet-based Polya Tree. See Ning (2018) <doi:10.1080/00949655.2017.1421194>.

Nonparametric kernel density estimation, bandwidth selection, and other utilities for analyzing directional data. Implements the estimator in Bai, Rao and Zhao (1987) <doi:10.1016/0047-259X(88)90113-3>, the cross-validation bandwidth selectors in Hall, Watson and Cabrera (1987) <doi:10.1093/biomet/74.4.751> and the plug-in bandwidth selectors in Garcà a-Portugués (2013) <doi:10.1214/13-ejs821>.

This package provides a collection of functions to preprocess data and organize them in a format amenable to use by chevron.

Estimates Two-way Fixed Effects difference-in-differences/event-study models using the approach proposed by Gardner (2021) <doi:10.48550/arXiv.2207.05943>. To avoid the problems caused by OLS estimation of the Two-way Fixed Effects model, this function first estimates the fixed effects and covariates using untreated observations and then in a second stage, estimates the treatment effects.

Clustered or multilevel data structures are common in the assessment of differential item functioning (DIF), particularly in the context of large-scale assessment programs. This package allows users to implement extensions of the Mantel-Haenszel DIF detection procedures in the presence of multilevel data based on the work of Begg (1999) <doi:10.1111/j.0006-341X.1999.00302.x>, Begg & Paykin (2001) <doi:10.1080/00949650108812115>, and French & Finch (2013) <doi:10.1177/0013164412472341>.

Create disposable R packages for testing. You can create, install and load multiple R packages with a single function call, and then unload, uninstall and destroy them with another function call. This is handy when testing how some R code or an R package behaves with respect to other packages.

This package provides data transformations, estimation utilities, predictive evaluation measures and simulation functions for discrete time survival analysis.

Plan optimal sample size allocation and go/no-go decision rules for phase II/III drug development programs with time-to-event, binary or normally distributed endpoints when assuming fixed treatment effects or a prior distribution for the treatment effect, using methods from Kirchner et al. (2016) <doi:10.1002/sim.6624> and Preussler (2020). Optimal is in the sense of maximal expected utility, where the utility is a function taking into account the expected cost and benefit of the program. It is possible to extend to more complex settings with bias correction (Preussler S et al. (2020) <doi:10.1186/s12874-020-01093-w>), multiple phase III trials (Preussler et al. (2019) <doi:10.1002/bimj.201700241>), multi-arm trials (Preussler et al. (2019) <doi:10.1080/19466315.2019.1702092>), and multiple endpoints (Kieser et al. (2018) <doi:10.1002/pst.1861>).

Computes the ATM (Attractor Transition Matrix) structure and the tree-like structure describing the cell differentiation process (based on the Threshold Ergodic Set concept introduced by Serra and Villani), starting from the Boolean networks with synchronous updating scheme of the BoolNet R package. TESs (Threshold Ergodic Sets) are the mathematical abstractions that represent the different cell types arising during ontogenesis. TESs and the powerful model of biological differentiation based on Boolean networks to which it belongs have been firstly described in "A Dynamical Model of Genetic Networks for Cell Differentiation" Villani M, Barbieri A, Serra R (2011) A Dynamical Model of Genetic Networks for Cell Differentiation. PLOS ONE 6(3): e17703.

The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology (Pinheiro et al. (2014) <doi:10.1002/sim.6052>).

Utilities for mixed frequency data. In particular, use to aggregate and normalize tabular mixed frequency data, index dates to end of period, and seasonally adjust tabular data.

Statistical deadband algorithms are based on the Send-On-Delta concept as in Miskowicz(2006,<doi:10.3390/s6010049>). A collection of functions compare effectiveness and fidelity of sampled signals using statistical deadband algorithms.

Estimate the Deterministic Input, Noisy "And" Gate (DINA) cognitive diagnostic model parameters using the Gibbs sampler described by Culpepper (2015) <doi:10.3102/1076998615595403>.

Flexible and efficient cleaning of data with interactivity. datacleanr facilitates best practices in data analyses and reproducibility with built-in features and by translating interactive/manual operations to code. The package is designed for interoperability, and so seamlessly fits into reproducible analyses pipelines in R'.

This package provides a R driver for Apache Drill<https://drill.apache.org>, which could connect to the Apache Drill cluster<https://drill.apache.org/docs/installing-drill-on-the-cluster> or drillbit<https://drill.apache.org/docs/embedded-mode-prerequisites> and get result(in data frame) from the SQL query and check the current configuration status. This link <https://drill.apache.org/docs> contains more information about Apache Drill.

Utility functions to be used to analyse datasets obtained from seed germination/emergence assays. Fits several types of seed germination/emergence models, including those reported in Onofri et al. (2018) "Hydrothermal-time-to-event models for seed germination", European Journal of Agronomy, 101, 129-139 <doi:10.1016/j.eja.2018.08.011>. Contains several datasets for practicing.