Companion package of Arnaud Barat, Andreu Sansó, Maite Arilla-Osuna, Ruth Blasco, Iñaki Pérez-Fernández, Gabriel Cifuentes-Alcobenda, Rubén Llorente, Daniel Vivar-Rà os, Ella Assaf, Ran Barkai, Avi Gopher, & Jordi Rosell-Ardèvol (2025), "Quantifying Diversity through Entropy Decomposition. Insights into Hominin Occupation and Carcass Processing at Qesem cave".

This package provides functionality to infer trajectories from single-cell data, represent them into a common format, and adapt them. Other biological information can also be added, such as cellular grouping, RNA velocity and annotation. Saelens et al. (2019) <doi:10.1038/s41587-019-0071-9>.

This package provides tools for exploring the topography of 3d triangle meshes. The functions were developed with dental surfaces in mind, but could be applied to any triangle mesh of class mesh3d'. More specifically, doolkit allows to isolate the border of a mesh, or a subpart of the mesh using the polygon networks method; crop a mesh; compute basic descriptors (elevation, orientation, footprint area); compute slope, angularity and relief index (Ungar and Williamson (2000) <https://palaeo-electronica.org/2000_1/gorilla/issue1_00.htm>; Boyer (2008) <doi:10.1016/j.jhevol.2008.08.002>), inclination and occlusal relief index or gamma (Guy et al. (2013) <doi:10.1371/journal.pone.0066142>), OPC (Evans et al. (2007) <doi:10.1038/nature05433>), OPCR (Wilson et al. (2012) <doi:10.1038/nature10880>), DNE (Bunn et al. (2011) <doi:10.1002/ajpa.21489>; Pampush et al. (2016) <doi:10.1007/s10914-016-9326-0>), form factor (Horton (1932) <doi:10.1029/TR013i001p00350>), basin elongation (Schum (1956) <doi:10.1130/0016-7606(1956)67[597:EODSAS]2.0.CO;2>), lemniscate ratio (Chorley et al; (1957) <doi:10.2475/ajs.255.2.138>), enamel-dentine distance (Guy et al. (2015) <doi:10.1371/journal.pone.0138802>; Thiery et al. (2017) <doi:10.3389/fphys.2017.00524>), absolute crown strength (Schwartz et al. (2020) <doi:10.1098/rsbl.2019.0671>), relief rate (Thiery et al. (2019) <doi:10.1002/ajpa.23916>) and area-relative curvature; draw cumulative profiles of a topographic variable; and map a variable over a 3d triangle mesh.

Analyses gene expression data derived from experiments to detect differentially expressed genes by employing the concept of majority voting with five different statistical models. It includes functions for differential expression analysis, significance testing, etc. It simplifies the process of uncovering meaningful patterns and trends within gene expression data, aiding researchers in downstream analysis. Boyer, R.S., Moore, J.S. (1991) <doi:10.1007/978-94-011-3488-0_5>.

Alpha and beta diversity for taxonomic (TD), functional (FD), and phylogenetic (PD) dimensions based on rasters. Spatial and temporal beta diversity can be partitioned into replacement and richness difference components. It also calculates standardized effect size for FD and PD alpha diversity and the average individual traits across multilayer rasters. The layers of the raster represent species, while the cells represent communities. Methods details can be found at Cardoso et al. 2022 <https://CRAN.R-project.org/package=BAT> and Heming et al. 2023 <https://CRAN.R-project.org/package=SESraster>.

Employ time-calibrated phylogenies and trait/range data to test for differences in diversification rates over evolutionary time. Extend the STRAPP test from BAMMtools::traitDependentBAMM() to any time step along phylogenies. See inst/COPYRIGHTS for details on third-party code.

Track and document dplyr data pipelines. As you filter, mutate, and join your way through a data set, dtrackr seamlessly keeps track of your data flow and makes publication ready documentation of a data pipeline simple.

Smooth testing of goodness of fit. These tests are data driven (alternative hypothesis is dynamically selected based on data). In this package you will find various tests for exponent, Gaussian, Gumbel and uniform distribution.

For working with the DataRobot predictive modeling platform's API <https://www.datarobot.com/>.

Integrated differential expression (DE) and differential co-expression (DC) analysis on gene expression data based on DECODE (DifferEntial CO-expression and Differential Expression) algorithm.

Several tests for differential methylation in methylation array data, including one-sided differential mean and variance test. Methods used in the package refer to Dai, J, Wang, X, Chen, H and others (2021) "Incorporating increased variability in discovering cancer methylation markers", Biostatistics, submitted.

This package performs the drifting Markov models (DMM) which are non-homogeneous Markov models designed for modeling the heterogeneities of sequences in a more flexible way than homogeneous Markov chains or even hidden Markov models. In this context, we developed an R package dedicated to the estimation, simulation and the exact computation of associated reliability of drifting Markov models. The implemented methods are described in Vergne, N. (2008), <doi:10.2202/1544-6115.1326> and Barbu, V.S., Vergne, N. (2019) <doi:10.1007/s11009-018-9682-8> .

This package provides Python-based extensions to enhance data analytics workflows, particularly for tasks involving data preprocessing and predictive modeling. Includes tools for data sampling, transformation, feature selection, balancing strategies (e.g., SMOTE), and model construction. These capabilities leverage Python libraries via the reticulate interface, enabling seamless integration with a broader machine learning ecosystem. Supports instance selection and hybrid workflows that combine R and Python functionalities for flexible and reproducible analytical pipelines. The architecture is inspired by the Experiment Lines approach, which promotes modularity, extensibility, and interoperability across tools. More information on Experiment Lines is available in Ogasawara et al. (2009) <doi:10.1007/978-3-642-02279-1_20>.

Item focussed recursive partitioning for simultaneous selection of items and variables that induce Differential Item Functioning (DIF) in dichotomous or polytomous items.

This package provides a Bayesian clustering method for replicated time series or replicated measurements from multiple experimental conditions, e.g., time-course gene expression data. It estimates the number of clusters directly from the data using a Dirichlet-process prior. See Fu, A. Q., Russell, S., Bray, S. and Tavare, S. (2013) Bayesian clustering of replicated time-course gene expression data with weak signals. The Annals of Applied Statistics. 7(3) 1334-1361. <doi:10.1214/13-AOAS650>.

Construction and analysis of matrix population models in R.

Estimates fractional trophic level from quantitative and qualitative diet data and calculates electivity indices in R. Borstein (2020) <doi:10.1007/s10750-020-04417-5>.

Geodesic distance between phylogenetic trees and associated functions. The theoretical background of distory is published in Billera et al. (2001) "Geometry of the space of phylogenetic trees." <doi:10.1006/aama.2001.0759>.

Allows to simulate SNP data using genlight objects. For example, it is straight forward to simulate a simple drift scenario with exchange of individuals between two populations or create a new genlight object based on allele frequencies of an existing genlight object.

This package provides a system for the management, assessment, and psychometric analysis of data from educational and psychological tests.

Fast distributed/parallel estimation for multinomial logistic regression via Poisson factorization and the gamlr package. For details see: Taddy (2015, AoAS), Distributed Multinomial Regression, <doi:10.48550/arXiv.1311.6139>.

Add a "Did You Mean" feature to the R interactive. With this package, error messages for misspelled input of variable names or package names suggest what you really want to do in addition to notification of the mistake.

This package provides functions to describe sampling and diversity dynamics of fossil occurrence datasets (e.g. from the Paleobiology Database). The package includes methods to calculate range- and occurrence-based metrics of taxonomic richness, extinction and origination rates, along with traditional sampling measures. A powerful subsampling tool is also included that implements frequently used sampling standardization methods in a multiple bin-framework. The plotting of time series and the occurrence data can be simplified by the functions incorporated in the package, as well as other calculations, such as environmental affinities and extinction selectivity testing. Details can be found in: Kocsis, A.T.; Reddin, C.J.; Alroy, J. and Kiessling, W. (2019) <doi:10.1101/423780>.

Fits, bootstraps, and evaluates two-component normal and lognormal mixture models. Includes diagnostic plots and statistical evaluation of mixture model fits using differential evolution optimization.