This package provides tools for the exploration of distributions of phylogenetic trees. This package includes a shiny interface which can be started from R using treespaceServer(). For further details see Jombart et al. (2017) <DOI:10.1111/1755-0998.12676>.

Deploy, execute, and analyze the results of models hosted on the ValidMind platform <https://validmind.com>. This package interfaces with the Python client library in order to allow advanced diagnostics and insight into trained models all from an R environment.

This R package analyzes high-throughput sequencing of T and B cell receptor complementarity determining region 3 (CDR3) sequences generated by Adaptive Biotechnologies ImmunoSEQ assay. Its input comes from tab-separated value (.tsv) files exported from the ImmunoSEQ analyzer.

This package provides fast maximum-likelihood phylogeny inference from noisy single-cell data using the ScisTree algorithm proposed by doi.org/10.1093/bioinformatics/btz676, Yufeng Wu (2019). It makes the method applicable to massive single-cell datasets (>10,000 cells).

The choices of color palettes in R can be quite overwhelming with palettes spread over many packages with many different API's. This package aims to collect all color palettes across the R ecosystem under the same package with a streamlined API.

This package aims to provide easy-to-use, efficient, flexible and scalable statistical tools. It provides and uses file-backed big matrices via memory-mapping. It provides for instance matrix operations, Principal Component Analysis, sparse linear supervised models, utility functions and more.

Patron is a Ruby HTTP client library based on libcurl. It does not try to expose the full power (read complexity) of libcurl but instead tries to provide a sane API while taking advantage of libcurl under the hood.

Blaze is an open-source, high-performance C++ math library for dense and sparse arithmetic. With its state-of-the-art Smart Expression Template implementation Blaze combines the elegance and ease of use of a domain-specific language with HPC-grade performance, making it one of the most intuitive and fastest C++ math libraries available. The RcppBlaze package includes the header files from the Blaze library with disabling some functionalities related to link to the thread and system libraries which make RcppBlaze be a header-only library. Therefore, users do not need to install Blaze'.

This package provides tools for optimal subset matching of treated units and control units in observational studies, with support for refined covariate balance constraints, (including fine and near-fine balance as special cases). A close relative is the rcbalance package. See Pimentel, et al.(2015) <doi:10.1080/01621459.2014.997879> and Pimentel and Kelz (2020) <doi:10.1080/01621459.2020.1720693>. The rrelaxiv package, which provides an alternative solver for the underlying network flow problems, carries an academic license and is not available on CRAN, but may be downloaded from Github at <https://github.com/josherrickson/rrelaxiv/>.

Record asciicast screen casts from R scripts. Convert them to animated SVG images, to be used in README files, or blog posts. Includes asciinema-player as an HTML widget, and an asciicast knitr engine, to embed ascii screen casts in Rmarkdown documents.

This is a port of the WTC MATLAB package written by Aslak Grinsted and the wavelet program written by Christopher Torrence and Gibert P. Compo. This package can be used to perform univariate and bivariate (cross-wavelet, wavelet coherence, wavelet clustering) analyses.

Interface to a high-performance implementation of k-medoids clustering described in Tiwari, Zhang, Mayclin, Thrun, Piech and Shomorony (2020) "BanditPAM: Almost Linear Time k-medoids Clustering via Multi-Armed Bandits" <https://proceedings.neurips.cc/paper/2020/file/73b817090081cef1bca77232f4532c5d-Paper.pdf>.

Convolute probabilistic distributions using the random generator function of each distribution. A new random number generator function is created that perform the mathematical operation on the individual random samples from the random generator function of each distribution. See the documentation for examples.

Allows users to seamlessly query several CDC PLACES APIs (<https://data.cdc.gov/browse?q=PLACES%20&sortBy=relevance>) by geography, state, measure, and release year. This package also contains a function to explore the available measures for each release year.

Compute the certainty equivalents and premium risks as tools for risk-efficiency analysis. For more technical information, please refer to: Hardaker, Richardson, Lien, & Schumann (2004) <doi:10.1111/j.1467-8489.2004.00239.x>, and Richardson, & Outlaw (2008) <doi:10.2495/RISK080231>.

Rare variant association test integrating variant position information. It aims to identify the presence of clusters of disease-risk variants in specific gene regions. For more details, please read the publication from Persyn et al. (2017) <doi:10.1371/journal.pone.0179364>.

Calculate cutoff values for model fit measures used in structural equation modeling (SEM) by simulating and testing data sets (cf. Hu & Bentler, 1999 <doi:10.1080/10705519909540118>) with the same parameters (population model, number of observations, etc.) as the model under consideration.

Measurement and partitioning of diversity, based on Tsallis entropy, following Marcon and Herault (2015) <doi:10.18637/jss.v067.i08>. entropart provides functions to calculate alpha, beta and gamma diversity of communities, including phylogenetic and functional diversity. Estimation-bias corrections are available.

This package implements Escalation With Overdose Control trial designs using two drug combinations described by this paper <doi:10.1002/sim.6961>(Tighiouart et al., 2016). It calculates the recommended dose for next cohorts and perform simulations to obtain operating characteristics.

It enables detailed interpretation of complex classification and regression models through Shapley analysis including data-driven characterization of subgroups of individuals. Furthermore, it facilitates multi-measure model evaluation, model fairness, and decision curve analysis. Additionally, it offers enhanced visualizations with interactive elements.

The ggplot2 package provides simple functions for visualizing contours of 2-d kernel density estimates. ggdensity implements several additional density estimators as well as more interpretable visualizations based on highest density regions instead of the traditional height of the estimated density surface.

Haplotype and covariate relative risks in case-control data are estimated by weighted logistic regression. Diplotype probabilities, which are estimated by EM computation with progressive insertion of loci, are utilized as weights. French et al. (2006) <doi:10.1002/gepi.20161>.

It performs maximum likelihood estimation for the Heckman selection model (Normal, Student-t or Contaminated normal) using an EM-algorithm <doi:10.1016/j.jmva.2021.104737>. It also performs influence diagnostic through global and local influence for four possible perturbation schema.

The MetAlyzer S4 object provides methods to read and reformat metabolomics data for convenient data handling, statistics and downstream analysis. The resulting format corresponds to input data of the Shiny app MetaboExtract (<https://www.metaboextract.shiny.dkfz.de/MetaboExtract/>).