Streamline the management, analysis, and visualization of CORINE Land Cover data. Addresses challenges associated with its classification system and related styles, such as color mappings and descriptive labels.

This package provides tools for working with the International Classification of Diseases ('ICD-10 Chile official MINSAL'/'DEIS v2018). Includes optimized SQL search with SQLite', fuzzy matching of medical terms ('Jaro-Winkler'), Charlson and Elixhauser comorbidity calculation, WHO ICD-11 API integration, and hierarchical code validation. Data from Centro FIC Chile DEIS <https://deis.minsal.cl/centrofic/>.

Predicts anticancer peptides using random forests trained on the n-gram encoded peptides. The implemented algorithm can be accessed from both the command line and shiny-based GUI. The CancerGram model is too large for CRAN and it has to be downloaded separately from the repository: <https://github.com/BioGenies/CancerGramModel>. For more information see: Burdukiewicz et al. (2020) <doi:10.3390/pharmaceutics12111045>.

Differential analyses and Enrichment pipeline for bulk ATAC-seq data analyses. This package combines different packages to have an ultimate package for both data analyses and visualization of ATAC-seq data. Methods are described in Karakaslar et al. (2021) <doi:10.1101/2021.03.05.434143>.

This package implements the JSON, INI, YAML and TOML parser for R setting and writing of configuration file. The functionality of this package is similar to that of package config'.

This software package provides Cox survival analysis for high-dimensional and multiblock datasets. It encompasses a suite of functions dedicated from the classical Cox regression to newest analysis, including Cox proportional hazards model, Stepwise Cox regression, and Elastic-Net Cox regression, Sparse Partial Least Squares Cox regression (sPLS-COX) incorporating three distinct strategies, and two Multiblock-PLS Cox regression (MB-sPLS-COX) methods. This tool is designed to adeptly handle high-dimensional data, and provides tools for cross-validation, plot generation, and additional resources for interpreting results. While references are available within the corresponding functions, key literature is mentioned below. Terry M Therneau (2024) <https://CRAN.R-project.org/package=survival>, Noah Simon et al. (2011) <doi:10.18637/jss.v039.i05>, Philippe Bastien et al. (2005) <doi:10.1016/j.csda.2004.02.005>, Philippe Bastien (2008) <doi:10.1016/j.chemolab.2007.09.009>, Philippe Bastien et al. (2014) <doi:10.1093/bioinformatics/btu660>, Kassu Mehari Beyene and Anouar El Ghouch (2020) <doi:10.1002/sim.8671>, Florian Rohart et al. (2017) <doi:10.1371/journal.pcbi.1005752>.

Extra family objects in "weird" scenarios, particularly logistic or log-linear model with unbounded or non-binary/non-integer outcomes. Provides binomial_extra() and poisson_extra() as generalizations of binomial() and poisson(). The use of canonical link with the corresponding working likelihood in glm() ensures convexity, making model fitting reliable and independent of starting value. Robert WM Wedderburn (1974) <doi:10.1093/biomet/61.3.439> and Peter McCullagh (1983) <doi:10.1214/aos/1176346056> justified this method to fit generalized linear (mean) models with quasi-/working likelihood.

This package provides access to the Calcite Design System javascript components via integration with the htmltools and shiny packages. Pre-built and interactive components can be used to generate either static html or interactive web applications. Learn more about the Calcite Design System at <https://developers.arcgis.com/calcite-design-system/>.

This package provides tools for Conditional Regime Analog Forecasting with Trajectories. The package builds lag and lead trajectory embeddings, detects regimes with singular value decomposition and changepoint analysis, estimates transition probabilities between regimes, samples future-trajectory analogues, and fits smooth empirical forecast distributions.

This package contains the probability density function, cumulative distribution function, quantile function, and random number generator for composite and discrete composite distributions with Pareto tails. The detailed description of the methods and the applications of the methods can be found in Bowen Liu, Malwane M.A. Ananda (2023) <arXiv:2309.16443>.

Statistical tests for the comparison between two or more alpha coefficients based on either dependent or independent groups of individuals. A web interface is available at http://comparingcronbachalphas.org. A plugin for the R GUI and IDE RKWard is included. Please install RKWard from https:// rkward.kde.org to use this feature. The respective R package rkward cannot be installed directly from a repository, as it is a part of RKWard.

Broken adaptive ridge estimator for censored data is used to select variables and estimate their coefficients in the semi-parametric accelerated failure time model for right-censored survival data.

This package provides a first-principle, phylogeny-aware comparative genomics tool for investigating associations between terms used to annotate genomic components (e.g., Pfam IDs, Gene Ontology terms,) with quantitative or rank variables such as number of cell types, genome size, or density of specific genomic elements. See the project website for more information, documentation and examples, and <doi:10.1016/j.patter.2023.100728> for the full paper.

Estimate coefficients of Cox proportional hazards model using stochastic gradient descent algorithm for batch data.

CODATA internationally recommended values of the fundamental physical constants, provided as symbols for direct use within the R language. Optionally, the values with uncertainties and/or units are also provided if the errors', units and/or quantities packages are installed. The Committee on Data for Science and Technology (CODATA) is an interdisciplinary committee of the International Council for Science which periodically provides the internationally accepted set of values of the fundamental physical constants. This package contains the "2022 CODATA" version, published on May 2024: Eite Tiesinga, Peter J. Mohr, David B. Newell, and Barry N. Taylor (2024) <https://physics.nist.gov/cuu/Constants/>.

The concaveman function ports the concaveman (<https://github.com/mapbox/concaveman>) library from mapbox'. It computes the concave polygon(s) for one or several set of points.

Package for CShapes 2.0, a GIS dataset of country borders (1886-today). Includes functions for data extraction and the computation of distance matrices and -lists.

This is an add-on to the cna package <https://CRAN.R-project.org/package=cna> comprising various functions for optimizing consistency and coverage scores of models of configurational comparative methods as Coincidence Analysis (CNA) and Qualitative Comparative Analysis (QCA). The function conCovOpt() calculates con-cov optima, selectMax() selects con-cov maxima among the con-cov optima, DNFbuild() can be used to build models actually reaching those optima, and findOutcomes() identifies those factor values in analyzed data that can be modeled as outcomes. For a theoretical introduction to these functions see Baumgartner and Ambuehl (2021) <doi:10.1177/0049124121995554>.

Hierarchical continuous (and discrete) time state space modelling, for linear and nonlinear systems measured by continuous variables, with limited support for binary data. The subject specific dynamic system is modelled as a stochastic differential equation (SDE) or difference equation, measurement models are typically multivariate normal factor models. Linear mixed effects SDE's estimated via maximum likelihood and optimization are the default. Nonlinearities, (state dependent parameters) and random effects on all parameters are possible, using either max likelihood / max a posteriori optimization (with optional importance sampling) or Stan's Hamiltonian Monte Carlo sampling. See <https://github.com/cdriveraus/ctsem/raw/master/vignettes/hierarchicalmanual.pdf> for details. See <https://osf.io/preprints/psyarxiv/4q9ex_v2> for a detailed tutorial. Priors may be used. For the conceptual overview of the hierarchical Bayesian linear SDE approach, see <https://www.researchgate.net/publication/324093594_Hierarchical_Bayesian_Continuous_Time_Dynamic_Modeling>. Exogenous inputs may also be included, for an overview of such possibilities see <https://www.researchgate.net/publication/328221807_Understanding_the_Time_Course_of_Interventions_with_Continuous_Time_Dynamic_Models> . <https://cdriver.netlify.app/> contains some tutorial blog posts.

This package provides a collection of tools for designing, implementing, testing, documenting and visualizing dynamic simulation cropping system models. Models are specified as a combination of state variables, parameters, intermediate factors and input data that define a system of ordinary differential equations. Specified models can be used to simulate dynamic processes using numerical integration algorithms.

In phase I clinical trials, the primary objective is to ascertain the maximum tolerated dose (MTD) corresponding to a specified target toxicity rate. The subsequent phase II trials are designed to examine the potential efficacy of the drug based on the MTD obtained from the phase I trials, with the aim of identifying the optimal biological dose (OBD). The CFO package facilitates the implementation of dose-finding trials by utilizing calibration-free odds type (CFO-type) designs. Specifically, it encompasses the calibration-free odds (CFO) (Jin and Yin (2022) <doi:10.1177/09622802221079353>), randomized CFO (rCFO), precision CFO (pCFO), two-dimensional CFO (2dCFO) (Wang et al. (2023) <doi:10.3389/fonc.2023.1294258>), time-to-event CFO (TITE-CFO) (Jin and Yin (2023) <doi:10.1002/pst.2304>), fractional CFO (fCFO), accumulative CFO (aCFO), TITE-aCFO, and f-aCFO (Fang and Yin (2024) <doi: 10.1002/sim.10127>). It supports phase I/II trials for the CFO design and only phase I trials for the other CFO-type designs. The â CFO package accommodates diverse CFO-type designs, allowing users to tailor the approach based on factors such as dose information inclusion, handling of late-onset toxicity, and the nature of the target drug (single-drug or drug-combination). The functionalities embedded in CFO package include the determination of the dose level for the next cohort, the selection of the MTD for a real trial, and the execution of single or multiple simulations to obtain operating characteristics. Moreover, these functions are equipped with early stopping and dose elimination rules to address safety considerations. Users have the flexibility to choose different distributions, thresholds, and cohort sizes among others for their specific needs. The output of the CFO package can be summary statistics as well as various plots for better visualization. An interactive web application for CFO is available at the provided URL.

This package provides tools for containerizing R projects. The core function, generate_dockerfile()', analyzes an R project's environment and dependencies via an renv lock file and generates a ready-to-use Dockerfile that encapsulates the computational setup. Designed to help researchers build portable, reproducible workflows that can be reliably shared, archived, and rerun across systems. See R Core Team (2025) <https://www.R-project.org/>, Ushey et al. (2025) <https://CRAN.R-project.org/package=renv>, and Docker Inc. (2025) <https://www.docker.com/>.

Create descriptive tables for continuous and categorical variables. Apply summary statistics and counting function, with or without a grouping variable, and create beautiful reports using rmarkdown or officer'. You can also compute effect sizes and statistical tests if needed.

This package contains selected variables from the time series profiles for statistical areas level 2 from the 2006, 2011, and 2016 censuses of population and housing, Australia. Also provides methods for viewing the questions asked for convenience during analysis.