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This package provides functions to have visualization and clean-up of enriched gene ontologies (GO) terms, protein complexes and pathways (obtained from multiple databases) using ConsensusPathDB from gene set over-expression analysis. Performs clustering of pathway based on similarity of over-expressed gene sets and visualizations similar to Ingenuity Pathway Analysis (IPA) when up and down regulated genes are known. The methods are described in a paper currently submitted by Orecchioni et al, 2020 in Nanoscale.
Robust estimation methods for the mean vector, scatter matrix, and covariance matrix (if it exists) from data (possibly containing NAs) under multivariate heavy-tailed distributions such as angular Gaussian (via Tyler's method), Cauchy, and Student's t distributions. Additionally, a factor model structure can be specified for the covariance matrix. The latest revision also includes the multivariate skewed t distribution. The package is based on the papers: Sun, Babu, and Palomar (2014); Sun, Babu, and Palomar (2015); Liu and Rubin (1995); Zhou, Liu, Kumar, and Palomar (2019); Pascal, Ollila, and Palomar (2021).
The free group in R; juxtaposition is represented by a plus. Includes inversion, multiplication by a scalar, group-theoretic power operation, and Tietze forms. To cite the package in publications please use Hankin (2022) <doi:10.48550/ARXIV.2212.05883>.
The proximate composition analysis is the quantification of main components that constitutes nutritional profile of any food and food products including fish, shellfish, fish feed and their ingredients. Understanding this composition is essential for evaluating their nutritional value and for making informed dietary choices. The primary components typically analyzed include; moisture/ water in foods, crude protein, crude fat/ lipid, total ash, fiber and carbohydrates AOAC(2005,ISBN:0-935584-77-3). In case of fish, shellfish and its products, the proximate composition consists of four primary constituents - water, protein, fat, and ash (mostly minerals). Fish exhibit significant variation in their chemical makeup based on age, sex, environment, and season, both within the same species and between individual fish. There is minimal fluctuation in the content of ash and protein. The lipid concentration varies remarkably and is inversely correlated with the water content. In case of fish, carbohydrates are present in minor quantity so that are quantified by subtracting total of other components from 100 to get percentage of carbohydrates.
Estimation and inference using the Fractionally Cointegrated Vector Autoregressive (VAR) model. It includes functions for model specification, including lag selection and cointegration rank selection, as well as a comprehensive set of options for hypothesis testing, including tests of hypotheses on the cointegrating relations, the adjustment coefficients and the fractional differencing parameters. An article describing the FCVAR model with examples is available on the Webpage <https://sites.google.com/view/mortennielsen/software>.
This package provides a program to generate smoothed quantiles for the Fst-heterozygosity distribution. Designed for use with large numbers of loci (e.g., genome-wide SNPs). The best case for analyzing the Fst-heterozygosity distribution is when many populations (>10) have been sampled. See Flanagan & Jones (2017) <doi:10.1093/jhered/esx048>.
Implementation of a simple algorithm designed for online multivariate changepoint detection of a mean in sparse changepoint settings. The algorithm is based on a modified cusum statistic and guarantees control of the type I error on any false discoveries, while featuring O(1) time and O(1) memory updates per series as well as a proven detection delay.
This is a method for Allele-specific DNA Copy Number profiling for whole-Exome sequencing data. Given the allele-specific coverage and site biases at the variant loci, this program segments the genome into regions of homogeneous allele-specific copy number. It requires, as input, the read counts for each variant allele in a pair of case and control samples, as well as the site biases. For detection of somatic mutations, the case and control samples can be the tumor and normal sample from the same individual. The implemented method is based on the paper: Chen, H., Jiang, Y., Maxwell, K., Nathanson, K. and Zhang, N. (under review). Allele-specific copy number estimation by whole Exome sequencing.
This package provides fast moving-window ("focal") and buffer-based extraction for raster data using the terra package. Automatically selects between a C++ backend (via terra') and a Fast Fourier Transform (FFT) backend depending on problem size. The FFT backend supports sum and mean, while other statistics (e.g., median, min, max, standard deviation) are handled by the terra backend. Supports multiple kernel types (e.g., circle, rectangle, gaussian), with NA handling consistent with terra via na.rm and na.policy'. Operates on SpatRaster objects and returns results with the same geometry.
Uses raw vectors to minimize memory consumption of categorical variables with fewer than 256 unique values. Useful for analysis of large datasets involving variables such as age, years, states, countries, or education levels.
Calculation of AHP (Analytic Hierarchy Process - <http://en.wikipedia.org/wiki/Analytic_hierarchy_process>) with classic and fuzzy weights based on Saaty's pairwise comparison method for determination of weights.
This package provides a novel forward stepwise discriminant analysis framework that integrates Pillai's trace with Uncorrelated Linear Discriminant Analysis (ULDA), providing an improvement over traditional stepwise LDA methods that rely on Wilks Lambda. A stand-alone ULDA implementation is also provided, offering a more general solution than the one available in the MASS package. It automatically handles missing values and provides visualization tools. For more details, see Wang (2024) <doi:10.48550/arXiv.2409.03136>.
This package provides a C++ API for routinely used numerical tools such as integration, root-finding, and optimization, where function arguments are given as lambdas. This facilitates Rcpp programming, enabling the development of R'-like code in C++ where functions can be defined on the fly and use variables in the surrounding environment.
Package for time value of money calculation, time series analysis and computational finance.
Discretely-sampled function is first smoothed. Features of the smoothed function are then extracted. Some of the key features include mean value, first and second derivatives, critical points (i.e. local maxima and minima), curvature of cunction at critical points, wiggliness of the function, noise in data, and outliers in data.
This package provides a web application for displaying, analysing and forecasting univariate time series. Includes basic methods such as mean, naïve, seasonal naïve and drift, as well as more complex methods such as Holt-Winters Box,G and Jenkins, G (1976) <doi:10.1111/jtsa.12194> and ARIMA Brockwell, P.J. and R.A.Davis (1991) <doi:10.1007/978-1-4419-0320-4>.
Processing of large-in-memory/large-on disk rasters and spatial vectors using GRASS <https://grass.osgeo.org/>. Most functions in the terra package are recreated. Processing of medium-sized and smaller spatial objects will nearly always be faster using terra or sf', but for large-in-memory/large-on-disk objects, fasterRaster may be faster. To use most of the functions, you must have the stand-alone version (not the OSGeoW4 installer version) of GRASS 8.0 or higher.
This package implements methods for network estimation and forecasting of high-dimensional time series exhibiting strong serial and cross-sectional correlations under a factor-adjusted vector autoregressive model. See Barigozzi, Cho and Owens (2024+) <doi:10.1080/07350015.2023.2257270> for further descriptions of FNETS methodology and Owens, Cho and Barigozzi (2024+) <arXiv:2301.11675> accompanying the R package.
The ability to tune models is important. finetune enhances the tune package by providing more specialized methods for finding reasonable values of model tuning parameters. Two racing methods described by Kuhn (2014) <doi:10.48550/arXiv.1405.6974> are included. An iterative search method using generalized simulated annealing (Bohachevsky, Johnson and Stein, 1986) <doi:10.1080/00401706.1986.10488128> is also included.
Links datasets through fuzzy string matching using pretrained text embeddings. Produces more accurate record linkage when lexical string distance metrics are a poor guide to match quality (e.g., "Patricia" is more lexically similar to "Patrick" than it is to "Trish"). Capable of performing multilingual record linkage. Methods are described in Ornstein (2025) <doi:10.1017/pan.2025.10016>.
This package provides methods to compute linear h-step ahead prediction coefficients based on localised and iterated Yule-Walker estimates and empirical mean squared and absolute prediction errors for the resulting predictors. Also, functions to compute autocovariances for AR(p) processes, to simulate tvARMA(p,q) time series, and to verify an assumption from Kley et al. (2019), Electronic of Statistics, forthcoming. Preprint <arXiv:1611.04460>.
Around 10% of almost any predictive modeling project is spent in predictive modeling, funModeling and the book Data Science Live Book (<https://livebook.datascienceheroes.com/>) are intended to cover remaining 90%: data preparation, profiling, selecting best variables dataViz', assessing model performance and other functions.
This package provides functions to switch the BLAS'/'LAPACK optimized backend and change the number of threads without leaving the R session, which needs to be linked against the FlexiBLAS wrapper library <https://www.mpi-magdeburg.mpg.de/projects/flexiblas>.
This package implements the new algorithm for fast computation of M-scatter matrices using a partial Newton-Raphson procedure for several estimators. The algorithm is described in Duembgen, Nordhausen and Schuhmacher (2016) <doi:10.1016/j.jmva.2015.11.009>.