This package creates diagrams with an object-oriented approach. Geometric objects have computed properties with information about themselves (e.g., their area) or about their relationships with other objects (e.g, the distance between their edges). The objects have methods to convert them to geoms that can be plotted in ggplot2'.

This package provides a simple, opinionated toolkit for visualizing genomic variant data using a ggplot2'-native grammar. Accepts VCF files or plain data frames and produces publication-ready lollipop plots, consequence summaries, mutational spectrum charts, and cohort-level comparisons with minimal code. Designed for both wet-lab biologists and experienced bioinformaticians.

Uses several types of indicator saturation and automated General-to-Specific (GETS) modelling from the gets package and applies it to panel data. This allows the detection of structural breaks in panel data, operationalising a reverse causal approach of causal inference, see Pretis and Schwarz (2022) <doi:10.2139/ssrn.4022745>.

Note that imageData has been superseded by growthPheno'. The package growthPheno incorporates all the functionality of imageData and has functionality not available in imageData', but some imageData functions have been renamed. The imageData package is no longer maintained, but is retained for legacy purposes.

Visualize interactions between multiple experimental factors using interactive 3D surface plots powered by plotly'. Instead of examining combinatorial pairwise interaction plots, map factor combinations to response surfaces and use surface crossings as geometric indicators of interaction effects. Supports continuous, categorical, and mixed factor designs with automatic binning for continuous conditioning variables.

Import, processing, validation, and visualization of personal light exposure measurement data from wearable devices. The package implements features such as the import of data and metadata files, conversion of common file formats, validation of light logging data, verification of crucial metadata, calculation of common parameters, and semi-automated analysis and visualization.

Nonparametric approach to estimate the location of block boundaries (change-points) of non-overlapping blocks in a random symmetric matrix which consists of random variables whose distribution changes from block to block. BRAULT Vincent, OUADAH Sarah, SANSONNET Laure and LEVY-LEDUC Celine (2017) <doi:10.1016/j.jmva.2017.12.005>.

Wrapper of the Petfinder API <https://www.petfinder.com/developers/v2/docs/> that implements methods for interacting with and extracting data from the Petfinder database. The Petfinder REST API allows access to the Petfinder database, one of the largest online databases of adoptable animals and animal welfare organizations across North America.

Reconstruct pedigrees from genotype data, by optimising the likelihood over all possible pedigrees subject to given restrictions. Tailor-made plots facilitate evaluation of the output. This package is part of the pedsuite ecosystem for pedigree analysis. In particular, it imports pedprobr for calculating pedigree likelihoods and forrel for estimating pairwise relatedness.

Integration of two data sources referred to the same target population which share a number of variables. Some functions can also be used to impute missing values in data sets through hot deck imputation methods. Methods to perform statistical matching when dealing with data from complex sample surveys are available too.

Useful to visualize the Poissoneity (an independent Poisson statistical framework, where each RNA measurement for each cell comes from its own independent Poisson distribution) of Unique Molecular Identifier (UMI) based single cell RNA sequencing (scRNA-seq) data, and explore cell clustering based on model departure as a novel data representation.

This package provides function for small area estimation at area level using averaging pseudo area level model for variables of interest. A dataset produced by data generation is also provided. This package estimates small areas at the village level and then aggregates them to the sub-district, region, and provincial levels.

This package provides tools for measuring similarity among documents and detecting passages which have been reused. Implements shingled n-gram, skip n-gram, and other tokenizers; similarity/dissimilarity functions; pairwise comparisons; minhash and locality sensitive hashing algorithms; and a version of the Smith-Waterman local alignment algorithm suitable for natural language.

Computes a zonohedron from real vector generators. The package also computes zonogons (2D zonotopes) and zonosegs (1D zonotopes). An elementary S3 class for matroids is included, which supports matroids with rank 3, 2, and 1. Optimization methods are taken from Heckbert (1985) <https://www.cs.cmu.edu/~ph/zono.ps.gz>.

This is an extension of the regression-based causal mediation analysis first proposed by Valeri and VanderWeele (2013) <doi:10.1037/a0031034> and Valeri and VanderWeele (2015) <doi:10.1097/EDE.0000000000000253>). It supports including effect measure modification by covariates(treatment-covariate and mediator-covariate product terms in mediator and outcome regression models) as proposed by Li et al (2023) <doi:10.1097/EDE.0000000000001643>. It also accommodates the original SAS macro and PROC CAUSALMED procedure in SAS when there is no effect measure modification. Linear and logistic models are supported for the mediator model. Linear, logistic, loglinear, Poisson, negative binomial, Cox, and accelerated failure time (exponential and Weibull) models are supported for the outcome model.

This package provides a client for the OmniPath web service and many other resources. It also includes functions to transform and pretty print some of the downloaded data, functions to access a number of other resources. Furthermore, OmnipathR features a close integration with the NicheNet method for ligand activity prediction from transcriptomics data.

This package provides tools to accurately estimate cell type abundances from heterogeneous bulk expression. A reference-based method utilizes single-cell information to generate a signature matrix and transformation of bulk expression for accurate regression based estimates. A marker-based method utilizes known cell-specific marker genes to measure relative abundances across samples.

This package is a collection of data analysis tools. It includes tools for regression outlier detection in a fitted linear model, stationary bootstrap using a truncated geometric distribution, a comprehensive test for weak stationarity, column means by group, weighted biplots, and a heuristic to obtain a better initial configuration in non-metric MDS.

Relx assembles releases for an Erlang/OTP release. Given a release specification and a list of directories in which to search for OTP applications it will generate a release output. That output depends heavily on what plugins available and what options are defined, but usually it is simply a well configured release directory.

Supplying gene expression data sets for the demos of the biclustering method "Factor Analysis for Bicluster Acquisition" (FABIA). The following three data sets are provided: A) breast cancer (van't Veer, Nature, 2002), B) multiple tissues (Su, PNAS, 2002), and C) diffuse large-B-cell lymphoma (Rosenwald, N Engl J Med, 2002).

FeatSeekR performs unsupervised feature selection using replicated measurements. It iteratively selects features with the highest reproducibility across replicates, after projecting out those dimensions from the data that are spanned by the previously selected features. The selected a set of features has a high replicate reproducibility and a high degree of uniqueness.

Geneplast is designed for evolutionary and plasticity analysis based on orthologous groups distribution in a given species tree. It uses Shannon information theory and orthologs abundance to estimate the Evolutionary Plasticity Index. Additionally, it implements the Bridge algorithm to determine the evolutionary root of a given gene based on its orthologs distribution.

The functions defined in this program serve for implementing adaptive two-stage tests. Currently, four tests are included: Bauer and Koehne (1994), Lehmacher and Wassmer (1999), Vandemeulebroecke (2006), and the horizontal conditional error function. User-defined tests can also be implemented. Reference: Vandemeulebroecke, An investigation of two-stage tests, Statistica Sinica 2006.

Clinical trial design for subgroup selection in three-stage group sequential trial as described in Lai, Lavori and Liao (2014, <doi:10.1016/j.cct.2014.09.001>). Includes facilities for design, exploration and analysis of such trials. An implementation of the initial DEFUSE-3 trial is also provided as a vignette.