The tidyomics ecosystem is a set of packages for ’omic data analysis that work together in harmony; they share common data representations and API design, consistent with the tidyverse ecosystem. The tidyomics package is designed to make it easy to install and load core packages from the tidyomics ecosystem with a single command.
transmogR provides the tools needed to crate a new reference genome or reference transcriptome, using a set of variants. Variants can be any combination of SNPs, Insertions and Deletions. The intended use-case is to enable creation of variant-modified reference transcriptomes for incorporation into transcriptomic pseudo-alignment workflows, such as salmon.
Frequentist inference on adaptively generated data. The methods implemented are based on Zhan et al. (2021) <doi:10.48550/arXiv.2106.02029> and Hadad et al. (2021) <doi:10.48550/arXiv.1911.02768>. For illustration, several functions for simulating non-contextual and contextual adaptive experiments using Thompson sampling are also supplied.
Fork of calendR R package to generate ready to print calendars with ggplot2 (see <https://r-coder.com/calendar-plot-r/>) with additional features (backwards compatible). calendRio provides a calendR() function that serves as a drop-in replacement for the upstream version but allows for additional parameters unlocking extra functionality.
Record and generate a gif of your R sessions plots. When creating a visualization, there is inevitably iteration and refinement that occurs. Automatically save the plots made to a specified directory, previewing them as they would be saved. Then combine all plots generated into a gif to show the plot refinement over time.
This package provides functions for computing the one-sided p-values of the Cochran-Armitage trend test statistic for the asymptotic and the exact conditional test. The computation of the p-value for the exact test is performed using an algorithm following an idea by Mehta, et al. (1992) <doi:10.2307/1390598>.
Dynamic Reservoir Simulation Model (DYRESM) and Computational Aquatic Ecosystem Dynamics Model (CAEDYM) model development, including assisting with calibrating selected model parameters and visualising model output through time series plot, profile plot, contour plot, and scatter plot. For more details, see Yu et al. (2023) <https://journal.r-project.org/articles/RJ-2023-008/>.
This package provides methods to simulate and analyse the size and length of branching processes with an arbitrary offspring distribution. These can be used, for example, to analyse the distribution of chain sizes or length of infectious disease outbreaks, as discussed in Farrington et al. (2003) <doi:10.1093/biostatistics/4.2.279>.
Construction, calculation and display of fault trees. Methods derived from Clifton A. Ericson II (2005, ISBN: 9780471739425) <DOI:10.1002/0471739421>, Antoine Rauzy (1993) <DOI:10.1016/0951-8320(93)90060-C>, Tim Bedford and Roger Cooke (2012, ISBN: 9780511813597) <DOI:10.1017/CBO9780511813597>, Nikolaos Limnios, (2007, ISBN: 9780470612484) <DOI: 10.1002/9780470612484>.
Additional annotations, stats, geoms and scales for plotting "light" spectra with ggplot2', together with specializations of ggplot() and autoplot() methods for spectral data and waveband definitions stored in objects of classes defined in package photobiology'. Part of the r4photobiology suite, Aphalo P. J. (2015) <doi:10.19232/uv4pb.2015.1.14>.
The getDTeval() function facilitates the translation of the original coding statement to an optimized form for improved runtime efficiency without compromising on the programmatic coding design. The function can either provide a translation of the coding statement, directly evaluate the translation to return a coding result, or provide both of these outputs.
Two novel matching-based methods for estimating group average treatment effects (GATEs). The match_y1y0() and match_y1y0_bc() functions are used for imputing the potential outcomes based on matching and bias-corrected matching techniques, respectively. The EstGATE() function is employed to estimate the GATE after imputing the potential outcomes.
This package provides tools for analyzing Marshall-Olkin shock models semi-independent time. It includes interactive shiny applications for exploring copula-based dependence structures, along with functions for modeling and visualization. The methods are based on Mijanovic and Popovic (2024, submitted) "An R package for Marshall-Olkin shock models with semi-independent times.".
It implements the online Bayesian methods for change point analysis. It can also perform missing data imputation with methods from VIM'. The reference is Yigiter A, Chen J, An L, Danacioglu N (2015) <doi:10.1080/02664763.2014.1001330>. The link to the package is <https://CRAN.R-project.org/package=onlineBcp>.
Run simulations or other functions while easily varying parameters from one iteration to the next. Some common use cases would be grid search for machine learning algorithms, running sets of simulations (e.g., estimating statistical power for complex models), or bootstrapping under various conditions. See the paramtest documentation for more information and examples.
Nomograms are constructed to predict the cumulative incidence rate which is calculated after adjusting for competing causes to the event of interest. K-fold cross-validation is implemented to validate predictive accuracy using a competing-risk version of the concordance index. Methods are as described in: Kattan MW, Heller G, Brennan MF (2003).
This package creates some tables of clinical study. Table 1 is created by table1() to describe baseline characteristics, which is essential in every clinical study. Created by table2(), the function of Table 2 is to explore influence factors. And Table 3 created by table3() is able to make stratified analysis.
RLassoCox is a package that implements the RLasso-Cox model proposed by Wei Liu. The RLasso-Cox model integrates gene interaction information into the Lasso-Cox model for accurate survival prediction and survival biomarker discovery. It is based on the hypothesis that topologically important genes in the gene interaction network tend to have stable expression changes. The RLasso-Cox model uses random walk to evaluate the topological weight of genes, and then highlights topologically important genes to improve the generalization ability of the Lasso-Cox model. The RLasso-Cox model has the advantage of identifying small gene sets with high prognostic performance on independent datasets, which may play an important role in identifying robust survival biomarkers for various cancer types.
r-kegggraph is an interface between Kegg Pathway database and graph object as well as a collection of tools to analyze, dissect and visualize these graphs. It parses the regularly updated kgml (Kegg XML) files into graph models maintaining all essential pathway attributes. The package offers functionalities including parsing, graph operation, visualization and etc.
This package provides an R interface to the Embedded COnic Solver (ECOS), an efficient and robust C library for convex problems. Conic and equality constraints can be specified in addition to integer and boolean variable constraints for mixed-integer problems. This R interface is inspired by the Python interface and has similar calling conventions.
This package provides a graph implementation that can be thought of as two tidy data frames describing node and edge data respectively. It provides an approach to manipulate these two virtual data frames using the API defined in the dplyr package, and it also provides tidy interfaces to a lot of common graph algorithms.
This package contains routines for logspline density estimation. The function oldlogspline() uses the same algorithm as the logspline package version 1.0.x; i.e., the Kooperberg and Stone (1992) algorithm (with an improved interface). The recommended routine logspline() uses an algorithm from Stone et al (1997).
The range of functions provided by this package makes it possible to draw highly versatile genomic sequence logos. Features include, but are not limited to, modifying colour schemes and fonts used to draw the logo, generating multiple logo plots, and aiding the visualisation with annotations. Sequence logos can easily be combined with other ggplot2 plots.
This package provides a user-friendly interface to map on-targets and off-targets of CRISPR gRNA spacer sequences using bwa. The alignment is fast, and can be performed using either commonly-used or custom CRISPR nucleases. The alignment can work with any reference or custom genomes. Currently not supported on Windows machines.