The software uses the copy number segments from a text file and identifies all chromosome arms that are globally altered and computes various genome-wide scores. The following HRD scores (characteristic of BRCA-mutated cancers) are included: LST, HR-LOH, nLST and gLOH. the package is tailored for the ThermoFisher Oncoscan assay analyzed with their Chromosome Alteration Suite (ChAS) but can be adapted to any input.

This package contains tools to fit the additive hazards model to data from a cohort, random sampling, two-phase Bernoulli sampling and two-phase finite population sampling, as well as calibration tool to incorporate phase I auxiliary information into the two-phase data model fitting. This package provides regression parameter estimates and their model-based and robust standard errors. It also offers tools to make prediction of individual specific hazards.

Loads and creates spatial data, including layers and tools that are relevant to the activities of the Commission for the Conservation of Antarctic Marine Living Resources. Provides two categories of functions: load functions and create functions. Load functions are used to import existing spatial layers from the online CCAMLR GIS such as the ASD boundaries. Create functions are used to create layers from user data such as polygons and grids.

The main objective of the package is to enter a word of at least two letters based on which an Iterated Function System with Probabilities is constructed, and a two-dimensional fractal containing the chosen word infinitely often is generated via the Chaos Game. Additionally, the package allows to project the two-dimensional fractal on several three-dimensional surfaces and to transform the fractal into another fractal with uniform marginals.

This package provides a novel framework to estimate mixed models via gradient boosting. The implemented functions are based on the mboost and lme4 packages, and the family range is therefore determined by lme4'. A correction mechanism for cluster-constant covariates is implemented, as well as estimation of the covariance of random effects. These methods are described in the accompanying publication; see <doi:10.1007/s11222-025-10612-y> for details.

Implementing a multiple imputation algorithm for multivariate data with missing and censored values under a coarsening at random assumption (Heitjan and Rubin, 1991<doi:10.1214/aos/1176348396>). The multiple imputation algorithm is based on the data augmentation algorithm proposed by Tanner and Wong (1987)<doi:10.1080/01621459.1987.10478458>. The Gibbs sampling algorithm is adopted to to update the model parameters and draw imputations of the coarse data.

The detection of worrying approximate collinearity in a multiple linear regression model is a problem addressed in all existing statistical packages. However, we have detected deficits regarding to the incorrect treatment of qualitative independent variables and the role of the intercept of the model. The objective of this package is to correct these deficits. In this package will be available detection and treatment techniques traditionally used as the recently developed.

Simulating data and fitting multi-species N-mixture models using nimble'. Includes features for handling zero-inflation and temporal correlation, Bayesian inference, model diagnostics, parameter estimation, and predictive checks. Designed for ecological studies with zero-altered or time-series data. Mimnagh, N., Parnell, A., Prado, E., & Moral, R. A. (2022) <doi:10.1007/s10651-022-00542-7>. Royle, J. A. (2004) <doi:10.1111/j.0006-341X.2004.00142.x>.

Supplemental functions and data for OpenIntro resources, which includes open-source textbooks and resources for introductory statistics (<https://www.openintro.org/>). The package contains datasets used in our open-source textbooks along with custom plotting functions for reproducing book figures. Note that many functions and examples include color transparency; some plotting elements may not show up properly (or at all) when run in some versions of Windows operating system.

This package provides a function kitten() which creates cute little packages which pass R package checks. This sets it apart from package.skeleton() which it calls, and which leaves imperfect files behind. As this is not exactly helpful for beginners, kitten() offers an alternative. Unit test support can be added via the tinytest package (if present), and documentation-creation support can be added via roxygen2 (if present).

Estimate sample size based on precision rather than power. precisely is a study planning tool to calculate sample size based on precision. Power calculations are focused on whether or not an estimate will be statistically significant; calculations of precision are based on the same principles as power calculation but turn the focus to the width of the confidence interval. precisely is based on the work of Rothman and Greenland (2018).

RStudio addin which provides a GUI to visualize and analyse networks. After finishing a session, the code to produce the plot is inserted in the current script. Alternatively, the function SNAhelperGadget() can be used directly from the console. Additional addins include the Netreader() for reading network files, Netbuilder() to create small networks via point and click, and the Componentlayouter() to layout networks with many components manually.

This package provides functions related to multivariate measures of independence and ICA: -estimate independent components by minimizing distance covariance; -conduct a test of mutual independence based on distance covariance; -estimate independent components via infomax (a popular method but generally performs poorer than mdcovica, ProDenICA, and/or fastICA, but is useful for comparisons); -order indepedent components by skewness; -match independent components from multiple estimates; -other functions useful in ICA.

Econometric estimation of simultaneous systems of linear and nonlinear equations using Ordinary Least Squares (OLS), Weighted Least Squares (WLS), Seemingly Unrelated Regressions (SUR), Two-Stage Least Squares (2SLS), Weighted Two-Stage Least Squares (W2SLS), and Three-Stage Least Squares (3SLS) as suggested, e.g., by Zellner (1962) <doi:10.2307/2281644>, Zellner and Theil (1962) <doi:10.2307/1911287>, and Schmidt (1990) <doi:10.1016/0304-4076(90)90127-F>.

If a procedure consists of several stages and there are several models that can be selected for each stage, uncertainty of the procedure can be decomposed by stages or models. This package includes the ANOVA-based method, the cumulative uncertainty-based method, and the balanced decomposition method. Yongdai Kim et al. (2019) <doi:10.1016/j.hydroa.2019.100024> is a related paper which is accessible via the URL below.

Offers a comprehensive set of assertion tests to help users validate the integrity of their data. These tests can be used to check for specific conditions or properties within a dataset and help ensure that data is accurate and reliable. The package is designed to make it easy to add quality control checks to data analysis workflows and to aid in identifying and correcting any errors or inconsistencies in data.

This package provides a visual and interactive web application using RStudio's shiny package. Bad quality samples are detected using sample-dependent and sample-independent controls present on the array and user adjustable thresholds. In depth exploration of bad quality samples can be performed using several interactive diagnostic plots of the quality control probes present on the array. Furthermore, the impact of any batch effect provided by the user can be explored.

This package provides classes for holding and manipulating Illumina methylation data. Based on eSet, it can contain MIAME information, sample information, feature information, and multiple matrices of data. An "intelligent" import function, methylumiR can read the Illumina text files and create a MethyLumiSet. methylumIDAT can directly read raw IDAT files from HumanMethylation27 and HumanMethylation450 microarrays. Normalization, background correction, and quality control features for GoldenGate, Infinium, and Infinium HD arrays are also included.

This package has been prepared to assist users in computing either a sample size or power value for a microarray experimental study. The user is referred to the cited references for technical background on the methodology underpinning these calculations. This package provides support for five types of sample size and power calculations. These five types can be adapted in various ways to encompass many of the standard designs encountered in practice.

This package provides tools to compute the center of gravity and moment of inertia tensor of any flying bird. The tools function by modeling a bird as a composite structure of simple geometric objects. This requires detailed morphological measurements of bird specimens although those obtained for the associated paper have been included in the package for use. Refer to the vignettes and supplementary material for detailed information on the package function.

Spatial modeling of energy balance and actual evapotranspiration using satellite images and meteorological data. Options of satellite are: Landsat-8 (with and without thermal bands), Sentinel-2 and MODIS. Respectively spatial resolutions are 30, 100, 10 and 250 meters. User can use data from a single meteorological station or a grid of meteorological stations (using any spatial interpolation method). Silva, Teixeira, and Manzione (2019) <doi:10.1016/j.envsoft.2019.104497>.

This package provides functions are provided to read and convert AIFF audio files to WAVE (WAV) format. This supports, for example, use of the tuneR package, which does not currently handle AIFF files. The AIFF file format is defined in <https://web.archive.org/web/20080125221040/http://www.borg.com/~jglatt/tech/aiff.htm> and <https://www.mmsp.ece.mcgill.ca/Documents/AudioFormats/AIFF/Docs/AIFF-1.3.pdf> .

Implement in R interactive Circos-like visualizations of genomic data, to map information such as genetic variants, genomic fusions and aberrations to a circular genome, as proposed by the JavaScript library BioCircos.js', based on the JQuery and D3 technologies. The output is by default displayed in stand-alone HTML documents or in the RStudio viewer pane. Moreover it can be integrated in R Markdown documents and Shiny applications.

Simulates time-to-event data with type I right censoring using two methods: the inverse CDF method and our proposed memoryless method. The latter method takes advantage of the memoryless property of survival and simulates a separate distribution between change-points. We include two parametric distributions: exponential and Weibull. Inverse CDF method draws on the work of Rainer Walke (2010), <https://www.demogr.mpg.de/papers/technicalreports/tr-2010-003.pdf>.