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The goal of gsDesign2 is to enable fixed or group sequential design under non-proportional hazards. To enable highly flexible enrollment, time-to-event and time-to-dropout assumptions, gsDesign2 offers piecewise constant enrollment, failure rates, and dropout rates for a stratified population. This package includes three methods for designs: average hazard ratio, weighted logrank tests in Yung and Liu (2019) <doi:10.1111/biom.13196>, and MaxCombo tests. Substantial flexibility on top of what is in the gsDesign package is intended for selecting boundaries.
Create plots that combine a phylogeny and frequency dynamics. Phylogenetic input can be a generic adjacency matrix or a tree of class "phylo". Inspired by similar plots in publications of the labs of RE Lenski and JE Barrick. Named for HJ Muller (who popularised such plots) and H Wickham (whose code this package exploits).
This package provides functions for fitting and doing predictions with Gaussian process models using Vecchia's (1988) approximation. Package also includes functions for reordering input locations, finding ordered nearest neighbors (with help from FNN package), grouping operations, and conditional simulations. Covariance functions for spatial and spatial-temporal data on Euclidean domains and spheres are provided. The original approximation is due to Vecchia (1988) <http://www.jstor.org/stable/2345768>, and the reordering and grouping methods are from Guinness (2018) <doi:10.1080/00401706.2018.1437476>. Model fitting employs a Fisher scoring algorithm described in Guinness (2019) <doi:10.48550/arXiv.1905.08374>.
This package provides functions for implementing the Generalized Bayesian Optimal Phase II (G-BOP2) design using various Particle Swarm Optimization (PSO) algorithms, including: - PSO-Default, based on Kennedy and Eberhart (1995) <doi:10.1109/ICNN.1995.488968>, "Particle Swarm Optimization"; - PSO-Quantum, based on Sun, Xu, and Feng (2004) <doi:10.1109/ICCIS.2004.1460396>, "A Global Search Strategy of Quantum-Behaved Particle Swarm Optimization"; - PSO-Dexp, based on StehlĂ k et al. (2024) <doi:10.1016/j.asoc.2024.111913>, "A Double Exponential Particle Swarm Optimization with Non-Uniform Variates as Stochastic Tuning and Guaranteed Convergence to a Global Optimum with Sample Applications to Finding Optimal Exact Designs in Biostatistics"; - and PSO-GO.
Gitea is a community managed, lightweight code hosting solution were projects and their respective git repositories can be managed <https://gitea.io>. This package gives an interface to the Gitea API to access and manage repositories, issues and organizations directly in R.
Geospatial data integration framework that merges raster, spatial polygon, and (dynamic) spatial points data into a spatial (panel) data frame at any geographical resolution.
Convert GDP time series data from one unit to another. All common GDP units are included, i.e. current and constant local currency units, US$ via market exchange rates and international dollars via purchasing power parities.
Provision of classes and methods for estimating generalized orthogonal GARCH models. This is an alternative approach to CC-GARCH models in the context of multivariate volatility modeling.
Genotype plus genotype-by-environment (GGE) biplots rendered using ggplot2'. Provides a command line interface to all of the functionality contained within the archived package GGEBiplotGUI'.
Analysis of complex ANOVA models with any combination of orthogonal/nested and fixed/random factors, as described by Underwood (1997). There are two restrictions: (i) data must be balanced; (ii) fixed nested factors are not allowed. Homogeneity of variances is checked using Cochran's C test and a posteriori comparisons of means are done using Student-Newman-Keuls (SNK) procedure. For those terms with no denominator in the F-ratio calculation, pooled mean squares and quasi F-ratios are provided. Magnitute of effects are assessed by components of variation.
This package provides functions to apply spatial fuzzy unsupervised classification, visualize and interpret results. This method is well suited when the user wants to analyze data with a fuzzy clustering algorithm and to account for the spatial dimension of the dataset. In addition, indexes for estimating the spatial consistency and classification quality are proposed. The methods were originally proposed in the field of brain imagery (seed Cai and al. 2007 <doi:10.1016/j.patcog.2006.07.011> and Zaho and al. 2013 <doi:10.1016/j.dsp.2012.09.016>) and recently applied in geography (see Gelb and Apparicio <doi:10.4000/cybergeo.36414>).
Toolset to create perpendicular profile graphs and swath profiles. Method are based on coordinate rotation algorithm by Schaeben et al. (2024) <doi:10.1002/mma.9823>.
This package provides a toolkit with functions to fit, plot, summarize, and apply Generalized Dissimilarity Models. Mokany K, Ware C, Woolley SNC, Ferrier S, Fitzpatrick MC (2022) <doi:10.1111/geb.13459> Ferrier S, Manion G, Elith J, Richardson K (2007) <doi:10.1111/j.1472-4642.2007.00341.x>.
Enables users to create simple plots of biological culture plates as well as microplates. Both continuous and discrete values can be plotted onto the plate layout.
This package provides classes and functions to calculate various distance measures and routes in heterogeneous geographic spaces represented as grids. The package implements measures to model dispersal histories first presented by van Etten and Hijmans (2010) <doi:10.1371/journal.pone.0012060>. Least-cost distances as well as more complex distances based on (constrained) random walks can be calculated. The distances implemented in the package are used in geographical genetics, accessibility indicators, and may also have applications in other fields of geospatial analysis.
Read, manipulate, and digitize landmark data, generate shape variables via Procrustes analysis for points, curves and surfaces, perform shape analyses, and provide graphical depictions of shapes and patterns of shape variation.
Detailed functionality for working with the univariate and multivariate Generalized Hyperbolic distribution and its special cases (Hyperbolic (hyp), Normal Inverse Gaussian (NIG), Variance Gamma (VG), skewed Student-t and Gaussian distribution). Especially, it contains fitting procedures, an AIC-based model selection routine, and functions for the computation of density, quantile, probability, random variates, expected shortfall and some portfolio optimization and plotting routines as well as the likelihood ratio test. In addition, it contains the Generalized Inverse Gaussian distribution. See Chapter 3 of A. J. McNeil, R. Frey, and P. Embrechts. Quantitative risk management: Concepts, techniques and tools. Princeton University Press, Princeton (2005).
Define, simulate, and validate stock-flow consistent (SFC) macroeconomic models. The godley R package offers tools to dynamically define model structures by adding variables and specifying governing systems of equations. With it, users can analyze how different macroeconomic structures affect key variables, perform parameter sensitivity analyses, introduce policy shocks, and visualize resulting economic scenarios. The accounting structure of SFC models follows the approach outlined in the seminal study by Godley and Lavoie (2007, ISBN:978-1-137-08599-3), ensuring a comprehensive integration of all economic flows and stocks. The algorithms implemented to solve the models are based on methodologies from Kinsella and O'Shea (2010) <doi:10.2139/ssrn.1729205>, Peressini and Sullivan (1988, ISBN:0-387-96614-5), and contributions by Joao Macalos.
Analytics to read in and segment raw GENEActiv accelerometer data into epochs and events. For more details on the GENEActiv device, see <https://activinsights.com/resources/geneactiv-support-1-2/>.
Likelihood ratio tests for genome-wide association and genome-wide linkage analysis under heterogeneity.
This package provides functions to develop simulated continuous data (e.g., gene expression) from a sigma covariance matrix derived from a graph structure in igraph objects. Intended to extend mvtnorm to take igraph structures rather than sigma matrices as input. This allows the use of simulated data that correctly accounts for pathway relationships and correlations. This allows the use of simulated data that correctly accounts for pathway relationships and correlations. Here we present a versatile statistical framework to simulate correlated gene expression data from biological pathways, by sampling from a multivariate normal distribution derived from a graph structure. This package allows the simulation of biological pathways from a graph structure based on a statistical model of gene expression. For example methods to infer biological pathways and gene regulatory networks from gene expression data can be tested on simulated datasets using this framework. This also allows for pathway structures to be considered as a confounding variable when simulating gene expression data to test the performance of genomic analyses.
The genridge package introduces generalizations of the standard univariate ridge trace plot used in ridge regression and related methods. These graphical methods show both bias (actually, shrinkage) and precision, by plotting the covariance ellipsoids of the estimated coefficients, rather than just the estimates themselves. 2D and 3D plotting methods are provided, both in the space of the predictor variables and in the transformed space of the PCA/SVD of the predictors.
This package provides a set of geometries to make line plots a little bit nicer. Use along with ggplot2 to: - Improve the clarity of line plots with many overlapping lines - Draw more realistic worms.
This package provides functions for plotting, and animating, the output of importance samplers, sequential Monte Carlo samplers (SMC) and ensemble-based methods. The package can be used to plot and animate histograms, densities, scatter plots and time series, and to plot the genealogy of an SMC or ensemble-based algorithm. These functions all rely on algorithm output to be supplied in tidy format. A function is provided to transform algorithm output from matrix format (one Monte Carlo point per row) to the tidy format required by the plotting and animating functions.