Allows users to import data files containing heartbeat positions in the most broadly used formats, to remove outliers or points with unacceptable physiological values present in the time series, to plot HRV data, and to perform time domain, frequency domain and nonlinear HRV analysis. See Garcia et al. (2017) <DOI:10.1007/978-3-319-65355-6>.

Manually bin data using weight of evidence and information value. Includes other binning methods such as equal length, quantile and winsorized. Options for combining levels of categorical data are also available. Dummy variables can be generated based on the bins created using any of the available binning methods. References: Siddiqi, N. (2006) <doi:10.1002/9781119201731.biblio>.

Imports real-time thermo cycler (qPCR) data from Real-time PCR Data Markup Language (RDML) and transforms to the appropriate formats of the qpcR and chipPCR packages, as described in Rodiger et al. (2017) <doi:10.1093/bioinformatics/btx528>. Contains a dendrogram visualization for the structure of RDML object and GUI for RDML editing.

Earth Engine <https://earthengine.google.com/> client library for R. All of the Earth Engine API classes, modules, and functions are made available. Additional functions implemented include importing (exporting) of Earth Engine spatial objects, extraction of time series, interactive map display, assets management interface, and metadata display. See <https://r-spatial.github.io/rgee/> for further details.

This package contains the Rook specification and convenience software for building and running Rook applications. A Rook application is an R reference class object that implements a call method or an R closure that takes exactly one argument, an environment, and returns a list with three named elements: the status, the headers, and the body.

This package provides methods to scan RR interval data for Premature Ventricular Complexes (PVCs) and parameterise and plot the resulting Heart Rate Turbulence (HRT). The methodology of HRT analysis is based on the original publication by Schmidt et al. <doi:10.1016/S0140-6736(98)08428-1> and extended with suggestions from <doi:10.1088/1361-6579/ab98b3>.

We introduce a robust matrix factor model that explicitly incorporates tail behavior and employs a mean-shift term to avoid efficiency losses through pre-centering of observed matrices. More details on the methods related to our paper are currently under submission. A full reference to the paper will be provided in future versions once the paper is published.

Focused on (but not exclusive to) data sets hosted on PhysioNet (<https://physionet.org>), ricu provides utilities for download, setup and access of intensive care unit (ICU) data sets. In addition to functions for running arbitrary queries against available data sets, a system for defining clinical concepts and encoding their representations in tabular ICU data is presented.

This R package is providing functions to perform geneset significance analysis over simple cross-sectional data between 2 and 5 phenotypes of interest.

This package contains functions for the efficient design of factorial two-colour microarray experiments and for the statistical analysis of factorial microarray data.

This package provides tools to read, write, create, and manipulate DESCRIPTION files. It is intended for packages that create or manipulate other packages.

This package provides software for the book Spectral Analysis for Physical Applications, Donald B. Percival and Andrew T. Walden, Cambridge University Press, 1993.

The package contains a modular pipeline for analysis of HELP microarray data, and includes graphical and mathematical tools with more general applications.

This package estimates epigenetic age in skeletal muscle, using DNA methylation data generated with the Illumina Infinium technology (HM27, HM450 and HMEPIC).

This package provides a model-based background correction method, which incorporates the negative control beads to pre-process Illumina BeadArray data.

This package provides functions for normalisation of two-color microarrays by optimised local regression and for detection of artefacts in microarray data.

Draw, manipulate, and evaluate directed acyclic graphs and simulate corresponding data, as described in International Journal of Epidemiology 50(6):1772-1777.

This package provides a simple and efficient wrapper around the fastest Fourier transform in the west (FFTW) library <http://www.fftw.org/>.

Routines for fitting various joint (and univariate) regression models, with several types of covariate effects, in the presence of equations errors association.

Convert Ensembl gene identifiers from Genotype-Tissue Expression (GTEx) data to identifiers in other annotation systems, including Entrez', HGNC', and UniProt'.

This package performs inference with the lasso in Gaussian Graphical Models. The package consists of wrappers for functions from the hdi package.

This package provides a simple tool allowing users to easily and dynamically explore or document a data set using a tree structure.

R functions for (non)linear time series analysis with an emphasis on nonparametric autoregression and order estimation, and tests for linearity / additivity.

Computes the Akaike information criterion for the generalized linear models (logistic regression, Poisson regression, and Gaussian graphical models) estimated by the lasso.