Adjusted odds ratio conditional on potential confounders can be directly obtained from logistic regression. However, those adjusted odds ratios have been widely incorrectly interpreted as a relative risk. As relative risk is often of interest in public health, we provide a simple code to return adjusted relative risks from logistic regression model under potential confounders.

Use of this package is deprecated. It has been renamed to LifeInsureR'.

Affords an alternative, vector-based syntax to lavaan', as well as other convenience functions such as naming paths and defining indirect links automatically, in addition to convenience formatting optimized for a publication and script sharing workflow.

Fit relationship-based and customized mixed-effects models with complex variance-covariance structures using the lme4 machinery. The core computational algorithms are implemented using the Eigen C++ library for numerical linear algebra and RcppEigen glue'.

This package performs Levins loop analysis of qualitatively-specified complex causal systems. Loop analysis makes qualitative predictions of variable change in a system of causally interdependent variables, where "qualitative" means direct causal relationships and indirect causal effects are coded as sign only (i.e. increases, decreases, no change, and ambiguous). This implementation includes output support for graphs in .dot file format for use with visualization software such as graphviz (<https://graphviz.org>). LoopAnalyst provides tools for the construction and output of community matrices, computation and output of community effect matrices, tables of correlations, adjoint, absolute feedback, weighted feedback and weighted prediction matrices, change in life expectancy matrices, and feedback, path and loop enumeration tools.

This package provides functions for genome-wide association studies (GWAS)/gene-environment-wide interaction studies (GEWIS) with longitudinal outcomes and exposures. He et al. (2017) "Set-Based Tests for Gene-Environment Interaction in Longitudinal Studies" and He et al. (2017) "Rare-variant association tests in longitudinal studies, with an application to the Multi-Ethnic Study of Atherosclerosis (MESA)".

LINCS L1000 is a high-throughput technology that allows the gene expression measurement in a large number of assays. However, to fit the measurements of ~1000 genes in the ~500 color channels of LINCS L1000, every two landmark genes are designed to share a single channel. Thus, a deconvolution step is required to infer the expression values of each gene. Any errors in this step can be propagated adversely to the downstream analyses. We present a LINCS L1000 data peak calling R package l1kdeconv based on a new outlier detection method and an aggregate Gaussian mixture model. Upon the remove of outliers and the borrowing information among similar samples, l1kdeconv shows more stable and better performance than methods commonly used in LINCS L1000 data deconvolution.

This package provides a wrapper built around the libLBFGS optimization library by Naoaki Okazaki. The lbfgs package implements both the Limited-memory Broyden-Fletcher-Goldfarb-Shanno (L-BFGS) and the Orthant-Wise Quasi-Newton Limited-Memory (OWL-QN) optimization algorithms. The L-BFGS algorithm solves the problem of minimizing an objective, given its gradient, by iteratively computing approximations of the inverse Hessian matrix. The OWL-QN algorithm finds the optimum of an objective plus the L1-norm of the problem's parameters. The package offers a fast and memory-efficient implementation of these optimization routines, which is particularly suited for high-dimensional problems.

This package provides tools for estimation and inference of conditional densities, derivatives and functions. This is the companion software for Cattaneo, Chandak, Jansson and Ma (2024) <doi:10.3150/23-BEJ1711>.

Determining consensus seriations for binary incidence matrices, using a two-step process of Procrustes-fit correspondence analysis for heuristic selection of partial seriations and iterative regression to establish a single consensus. Contains the Lakhesis Calculator, a graphical platform for identifying seriated sequences. Collins-Elliott (2024) <https://volweb.utk.edu/~scolli46/sceLakhesis.pdf>.

This package provides functions to prepare, visualize, and analyse diachronic network data on local political actors, with a particular focus on the development of local party systems and identification of actor groups. Formalizes and automates a continuity diagram method that has been previously applied in research on Czech local politics, e.g. Bubenicek and Kubalek (2010, ISSN:1803-8220), Kubalek and Bubenicek (2012, ISSN:1803-8220), and Cmejrek, Bubenicek, and Copik (2010, ISBN:978-80-247-3061-5). The package also includes several example datasets derived from Czech municipal elections, compiled from official election results, field research, and previously published case studies on Czech local politics.

This package provides in built datasets and three functions. These functions are mobility_index, nonStanTest and linkedLives. The mobility_index function facilitates the calculation of lifecourse fluidity, whilst the nonStanTest and the linkedLives functions allow the user to determine the probability that the observed sequence data was due to chance. The linkedLives function acknowledges the fact that some individuals may have identical sequences. The datasets available provide sequence data on marital status(maritalData) and mobility (mydata) for a selected group of individuals from the British Household Panel Study (BHPS). In addition, personal and house ID's for 100 individuals are provided in a third dataset (myHouseID) from the BHPS.

Mixture modelling of one-dimensional data using combinations of left-truncated Gamma, Weibull, and Lognormal Distributions. Blostein, Martin & Miljkovic, Tatjana. (2019) <doi:10.1016/j.insmatheco.2018.12.001>.

Estimate the slope and intercept of a bivariate linear relationship by calculating a posterior density that is invariant to interchange and scaling of the coordinates.

Whole-buffer DEFLATE-based compression and decompression of raw vectors using the libdeflate library (see <https://github.com/ebiggers/libdeflate>). Provides the user with additional control over the speed and the quality of DEFLATE compression compared to the fixed level of compression offered in R's memCompress() function. Also provides the libdeflate static library and C headers along with a CMake target and packageâ config file that ease linking of libdeflate in packages that compile and statically link bundled libraries using CMake'.

Collections of functions allowing random number generations and estimation of Liouville copulas, as described in Belzile and Neslehova (2017) <doi:10.1016/j.jmva.2017.05.008>.

This package provides a utility to facilitate the logging and review of R programs in clinical trial programming workflows.

This package provides tools for creating and using lenses to simplify data manipulation. Lenses are composable getter/setter pairs for working with data in a purely functional way. Inspired by the Haskell library lens (Kmett, 2012) <https://hackage.haskell.org/package/lens>. For a fairly comprehensive (and highly technical) history of lenses please see the lens wiki <https://github.com/ekmett/lens/wiki/History-of-Lenses>.

This package produces high resolution, publication ready linkage maps and quantitative trait loci maps. Input can be output from R/qtl', simple text or comma delimited files. Output is currently a portable document file.

Estimation of the local false discovery rate using the method of moments.

Exact significance tests for a changepoint in linear or multiple linear regression. Confidence regions with exact coverage probabilities for the changepoint. Based on Knowles, Siegmund and Zhang (1991) <doi:10.1093/biomet/78.1.15>.

Fast calculation of Area Under Curve (AUC) metric of a Receiver Operating Characteristic (ROC) curve, using the algorithm of Fawcett (2006) <doi:10.1016/j.patrec.2005.10.010>. Therefore it is appropriate for large-scale AUC metric calculations.

Print vectors (and data frames) of floating point numbers using a non-scientific format optimized for human readers. Vectors of numbers are rounded using significant digits, aligned at the decimal point, and all zeros trailing the decimal point are dropped. See: Wright (2016). Lucid: An R Package for Pretty-Printing Floating Point Numbers. In JSM Proceedings, Statistical Computing Section. Alexandria, VA: American Statistical Association. 2270-2279.

Instrumental variables (IVs) are a popular and powerful tool for estimating causal effects in the presence of unobserved confounding. However, classical methods rely on strong assumptions such as the exclusion criterion, which states that instrumental effects must be entirely mediated by treatments. In the so-called "leaky" IV setting, candidate instruments are allowed to have some direct influence on outcomes, rendering the average treatment effect (ATE) unidentifiable. But with limits on the amount of information leakage, we may still recover sharp bounds on the ATE, providing partial identification. This package implements methods for ATE bounding in the leaky IV setting with linear structural equations. For details, see Watson et al. (2024) <doi:10.48550/arXiv.2404.04446>.