This package provides functions to generate or sample from all possible splits of features or variables into a number of specified groups. Also computes the best split selection estimator (for low-dimensional data) as defined in Christidis, Van Aelst and Zamar (2019) <arXiv:1812.05678>.

The package is used for calibrating the design parameters for single-to-double arm transition design proposed by Shi and Yin (2017). The calibration is performed via numerical enumeration to find the optimal design that satisfies the constraints on the type I and II error rates.

Total variation denoising can be used to approximate a given sequence of noisy observations by a piecewise constant sequence, with adaptively-chosen break points. An efficient linear-time algorithm for total variation denoising is provided here, based on Johnson (2013) <doi:10.1080/10618600.2012.681238>.

This package implements the Whale Optimization Algorithm(WOA) for k-medoids clustering, providing tools for effective and efficient cluster analysis in various data sets. The methodology is based on "The Whale Optimization Algorithm" by Mirjalili and Lewis (2016) <doi:10.1016/j.advengsoft.2016.01.008>.

This package provides a collection of tools to streamline the process of fitting elastic net models with glmnet. In addition to providing a formula interface, it also features a function cva.glmnet to do crossvalidation for both α and λ, as well as some utility functions.

This package provides sparse vectors powered by ALTREP (Alternative Representations for R Objects) that behave like regular vectors, and can thus be used in data frames. It also provides tools to convert between sparse matrices and data frames with sparse columns and functions to interact with sparse vectors.

This package provides a normalization method for single-cell UMI count data using a variance stabilizing transformation. The transformation is based on a negative binomial regression model with regularized parameters. As part of the same regression framework, this package also provides functions for batch correction, and data correction.

RealGUD is a modular, extensible GNU Emacs front-end for interacting with external debuggers. It integrates various debuggers such as gdb, pdb, ipdb, jdb, lldb, bashdb, zshdb, etc. and allows visually steping through code in the sources. Unlike GUD, it also supports running multiple debug sessions in parallel.

The cane gem provides a great framework for running quality checks over your ruby project as part of continuous integration build. It comes with a few checks out of the box, but also provides an API for loading custom checks. This gem provides a set of additional checks.

Mustache is a framework-agnostic way to render logic-free views. Think of Mustache as a replacement for your views. Instead of views consisting of ERB or HAML with random helpers and arbitrary logic, your views are broken into two parts: a Ruby class and an HTML template.

Set of functions for estimation of cyclical characteristics, such as period, phase, amplitude, and statistical significance in large temporal datasets. Supporting functions are available for quality control, dimensionality reduction, spectral analysis, and analysis of experimental replicates. Contains a R Shiny web interface to execute all workflow steps.

This package provides methods to estimate optimal dynamic treatment regimes using Bayesian likelihood-based regression approach as described in Yu, W., & Bondell, H. D. (2023) <doi:10.1093/jrsssb/qkad016> Uses backward induction and dynamic programming theory for computing expected values. Offers options for future parallel computing.

Fiducial framework to perform inference on the quantiles for a generalized Pareto distribution model and on the parameters of the Pareto exceedance distribution, assuming the exceedance threshold is a known or unknown parameter. Reference: Damian V. Wandler & Jan Hannig (2012) <doi:10.1007/s10687-011-0127-9>.

Play and record games of minesweeper using a graphics device that supports event handling. Replay recorded games and save GIF animations of them. Based on classic minesweeper as detailed by Crow P. (1997) <https://minesweepergame.com/math/a-mathematical-introduction-to-the-game-of-minesweeper-1997.pdf>.

Gene selection based on variance using the marginal distributions of gene profiles that characterized by a mixture of three-component multivariate distributions. Please see the reference: Li X, Fu Y, Wang X, DeMeo DL, Tantisira K, Weiss ST, Qiu W. (2018) <doi:10.1155/2018/6591634>.

Create and customize interactive phylogenetic trees using the phylocanvas JavaScript library and the htmlwidgets package. These trees can be used directly from the R console, from RStudio', in Shiny apps, and in R Markdown documents. See <http://phylocanvas.org/> for more information on the phylocanvas library.

When working across multiple machines and, similarly for reproducible research, it can be time consuming to ensure that you have all of the needed packages installed and loaded and that the correct working directory is set. simpleSetup provides simple functions for making these tasks more straightforward.

Transport theory has seen much success in many fields of statistics and machine learning. We provide a variety of algorithms to compute Wasserstein distance, barycenter, and others. See Peyré and Cuturi (2019) <doi:10.1561/2200000073> for the general exposition to the study of computational optimal transport.

Evaluation of prediction performance of smaller regions of spectra for Chemometrics. Segmentation of spectra, evolving dimensions regions and sliding windows as selection methods. Election of the best model among those computed based on error metrics. Chen et al.(2017) <doi:10.1007/s00216-017-0218-9>.

The scDblFinder package gathers various methods for the detection and handling of doublets/multiplets in single-cell RNA sequencing data (i.e. multiple cells captured within the same droplet or reaction volume). It includes methods formerly found in the scran package, and the new fast and comprehensive scDblFinder method.

ProteoDisco is an R package to facilitate proteogenomics studies. It houses functions to create customized (variant) protein databases based on user-submitted genomic variants, splice-junctions, fusion genes and manual transcript sequences. The flexible workflow can be adopted to suit a myriad of research and experimental settings.

Estimate ideal efficiencies of aerosol sampling through sample lines. Functions were developed consistent with the approach described in Hogue, Mark; Thompson, Martha; Farfan, Eduardo; Hadlock, Dennis, (2014), "Hand Calculations for Transport of Radioactive Aerosols through Sampling Systems" Health Phys 106, 5, S78-S87, <doi:10.1097/HP.0000000000000092>.

This package provides a novel parametrization of log transformation and a shift parameter to automate the transformation process are proposed in R package AutoTransQF based on Feng et al. (2016). Please read Feng et al. (2016) <doi:10.1002/sta4.104> for more details of the method.

This package provides a set of tools to read, analyze and write lists of click sequences on websites (i.e., clickstream). A click can be represented by a number, character or string. Clickstreams can be modeled as zero- (only computes occurrence probabilities), first- or higher-order Markov chains.