_            _    _        _         _
      /\ \         /\ \ /\ \     /\_\      / /\
      \_\ \       /  \ \\ \ \   / / /     / /  \
      /\__ \     / /\ \ \\ \ \_/ / /     / / /\ \__
     / /_ \ \   / / /\ \ \\ \___/ /     / / /\ \___\
    / / /\ \ \ / / /  \ \_\\ \ \_/      \ \ \ \/___/
   / / /  \/_// / /   / / / \ \ \        \ \ \
  / / /      / / /   / / /   \ \ \   _    \ \ \
 / / /      / / /___/ / /     \ \ \ /_/\__/ / /
/_/ /      / / /____\/ /       \ \_\\ \/___/ /
\_\/       \/_________/         \/_/ \_____\/
r-decomptumor2sig 2.26.0
Dependencies: perl@5.36.0
Propagated dependencies: r-biocgenerics@0.56.0 r-biostrings@2.78.0 r-bsgenome-hsapiens-ucsc-hg19@1.4.3 r-data-table@1.17.8 r-genomicfeatures@1.62.0 r-genomicranges@1.62.0 r-ggplot2@4.0.1 r-ggseqlogo@0.2 r-gridextra@2.3 r-matrix@1.7-4 r-plyr@1.8.9 r-quadprog@1.5-8 r-readxl@1.4.5 r-s4vectors@0.48.0 r-seqinfo@1.0.0 r-summarizedexperiment@1.40.0 r-txdb-hsapiens-ucsc-hg19-knowngene@3.22.1 r-variantannotation@1.56.0
Channel: guix
Location: gnu/packages/bioconductor.scm (gnu packages bioconductor)
Home page: https://rmpiro.net/decompTumor2Sig/
Licenses: GPL 2
Synopsis: Decomposition of individual tumors into mutational signatures
Description:

The package uses quadratic programming for signature refitting, i.e., to decompose the mutation catalog from an individual tumor sample into a set of given mutational signatures (either Alexandrov-model signatures or Shiraishi-model signatures), computing weights that reflect the contributions of the signatures to the mutation load of the tumor.

Total results: 1