r-decomptumor2sig 2.28.0
Dependencies: perl@5.36.0
Propagated dependencies: r-biocgenerics@0.58.1 r-biostrings@2.80.1 r-bsgenome-hsapiens-ucsc-hg19@1.4.3 r-data-table@1.18.4 r-genomicfeatures@1.64.0 r-genomicranges@1.64.0 r-ggplot2@4.0.3 r-ggseqlogo@0.2.2 r-gridextra@2.3 r-matrix@1.7-5 r-plyr@1.8.9 r-quadprog@1.5-8 r-readxl@1.5.0 r-s4vectors@0.50.1 r-seqinfo@1.2.0 r-summarizedexperiment@1.42.0 r-txdb-hsapiens-ucsc-hg19-knowngene@3.22.1 r-variantannotation@1.58.0
Channel: guix
Home page: https://rmpiro.net/decompTumor2Sig/
Licenses: GPL 2
Build system: r
Synopsis: Decomposition of individual tumors into mutational signatures
Description:
The package uses quadratic programming for signature refitting, i.e., to decompose the mutation catalog from an individual tumor sample into a set of given mutational signatures (either Alexandrov-model signatures or Shiraishi-model signatures), computing weights that reflect the contributions of the signatures to the mutation load of the tumor.
Total packages: 1