This package provides a shiny application to compute daily and cumulative degree-days from minimum and maximum temperatures using average, single triangle, and single sine methods, with optional upper temperature thresholds. The application maps cumulative thermal accumulation to user-defined developmental stage thresholds and supports exporting tabular and graphical outputs. The degree-day approach follows assumptions described by Higley et al. (1986) <doi:10.1093/ee/15.5.999>.

Programmatic interface to the Daymet web services (<http://daymet.ornl.gov>). Allows for easy downloads of Daymet climate data directly to your R workspace or your computer. Routines for both single pixel data downloads and gridded (netCDF) data are provided.

Extends package distr by functionals, distances, and conditional distributions.

Perform data quality assessment ('DQA') of electronic health records ('EHR'). Publication: Kapsner et al. (2021) <doi:10.1055/s-0041-1733847>.

Estimation of the average treatment effect when controlling for high-dimensional confounders using debiased inverse propensity score weighting (DIPW). DIPW relies on the propensity score following a sparse logistic regression model, but the regression curves are not required to be estimable. Despite this, our package also allows the users to estimate the regression curves and take the estimated curves as input to our methods. Details of the methodology can be found in Yuhao Wang and Rajen D. Shah (2020) "Debiased Inverse Propensity Score Weighting for Estimation of Average Treatment Effects with High-Dimensional Confounders" <arXiv:2011.08661>. The package relies on the optimisation software MOSEK <https://www.mosek.com/> which must be installed separately; see the documentation for Rmosek'.

This package provides a versatile toolkit for analyzing and visualizing DEXi (Decision EXpert for education) decision trees, facilitating multi-criteria decision analysis directly within R. Users can read .dxi files, manipulate decision trees, and evaluate various scenarios. It supports sensitivity analysis through Monte Carlo simulations, one-at-a-time approaches, and variance-based methods, helping to discern the impact of input variations. Additionally, it includes functionalities for generating sampling plans and an array of visualization options for decision trees and analysis results. A distinctive feature is the synoptic table plot, aiding in the efficient comparison of scenarios. Whether for in-depth decision modeling or sensitivity analysis, this package stands as a comprehensive solution. Definition of sensitivity analyses available in Carpani, Bergez and Monod (2012) <doi:10.1016/j.envsoft.2011.10.002> and detailed description of the package soon available in Alaphilippe et al. (2025) <doi:10.1016/j.simpa.2024.100729>.

This package provides a wide collection of univariate discrete data sets from various applied domains related to distribution theory. The functions allow quick, easy, and efficient access to 100 univariate discrete data sets. The data are related to different applied domains, including medical, reliability analysis, engineering, manufacturing, occupational safety, geological sciences, terrorism, psychology, agriculture, environmental sciences, road traffic accidents, demography, actuarial science, law, and justice. The documentation, along with associated references for further details and uses, is presented.

Discrete factor analysis for dependent Poisson and negative binomial models with truncation, zero inflation, and zero inflated truncation.

Reverse and model the effects of changing deposition rates on geological data and rates. Based on Hohmann (2018) <doi:10.13140/RG.2.2.23372.51841> .

This package provides functionality to infer trajectories from single-cell data, represent them into a common format, and adapt them. Other biological information can also be added, such as cellular grouping, RNA velocity and annotation. Saelens et al. (2019) <doi:10.1038/s41587-019-0071-9>.

Discretization-based random sampling algorithm that is useful for a complex model in high dimension is implemented. The normalizing constant of a target distribution is not needed. Posterior summaries are compared with those by OpenBUGS'. The method is described: Wang and Lee (2014) <doi:10.1016/j.csda.2013.06.011> and exercised in Lee (2009) <http://hdl.handle.net/1993/21352>.

Data package for dartR'. Provides data sets to run examples in dartR'. This was necessary due to the size limit imposed by CRAN'. The data in dartR.data is needed to run the examples provided in the dartR functions. All available data sets are either based on actual data (but reduced in size) and/or simulated data sets to allow the fast execution of examples and demonstration of the functions.

Various kinds of designs for (industrial) experiments can be created. The package uses, and sometimes enhances, design generation routines from other packages. So far, response surface designs from package rsm', Latin hypercube samples from packages lhs and DiceDesign', and D-optimal designs from package AlgDesign have been implemented.

Abstract of Manuscript. Differential gene expression analysis using RNA sequencing (RNA-seq) data is a standard approach for making biological discoveries. Ongoing large-scale efforts to process and normalize publicly available gene expression data enable rapid and systematic reanalysis. While several powerful tools systematically process RNA-seq data, enabling their reanalysis, few resources systematically recompute differentially expressed genes (DEGs) generated from individual studies. We developed a robust differential expression analysis pipeline to recompute 3162 human DEG lists from The Cancer Genome Atlas, Genotype-Tissue Expression Consortium, and 142 studies within the Sequence Read Archive. After measuring the accuracy of the recomputed DEG lists, we built the Differential Expression Enrichment Tool (DEET), which enables users to interact with the recomputed DEG lists. DEET, available through CRAN and RShiny, systematically queries which of the recomputed DEG lists share similar genes, pathways, and TF targets to their own gene lists. DEET identifies relevant studies based on shared results with the userâ s gene lists, aiding in hypothesis generation and data-driven literature review. Sokolowski, Dustin J., et al. "Differential Expression Enrichment Tool (DEET): an interactive atlas of human differential gene expression." Nucleic Acids Research Genomics and Bioinformatics (2023).

Discriminant Non-Negative Matrix Factorization aims to extend the Non-negative Matrix Factorization algorithm in order to extract features that enforce not only the spatial locality, but also the separability between classes in a discriminant manner. It refers to three article, Zafeiriou, Stefanos, et al. "Exploiting discriminant information in nonnegative matrix factorization with application to frontal face verification." Neural Networks, IEEE Transactions on 17.3 (2006): 683-695. Kim, Bo-Kyeong, and Soo-Young Lee. "Spectral Feature Extraction Using dNMF for Emotion Recognition in Vowel Sounds." Neural Information Processing. Springer Berlin Heidelberg, 2013. and Lee, Soo-Young, Hyun-Ah Song, and Shun-ichi Amari. "A new discriminant NMF algorithm and its application to the extraction of subtle emotional differences in speech." Cognitive neurodynamics 6.6 (2012): 525-535.

This package provides a modular package for measuring disparity (multidimensional space occupancy). Disparity can be calculated from any matrix defining a multidimensional space. The package provides a set of implemented metrics to measure properties of the space and allows users to provide and test their own metrics. The package also provides functions for looking at disparity in a serial way (e.g. disparity through time) or per groups as well as visualising the results. Finally, this package provides several statistical tests for disparity analysis.

This package provides functions for reading DCP and CDF.bin files generated by the dChip software.

Uses the delta-method to estimate the Potential Impact Fraction (PIF) and the Population Attributable Fraction (PAF) from summary data. It creates point-estimates, confidence intervals, and estimates of the variance. Provides an extension to the aggregated data method in Chan, Zepeda-Tello et al (2025) <doi:10.1002/sim.70214>.

Robust distance-based methods applied to matrices and data frames, producing distance matrices that can be used as input for various visualization techniques such as graphs, heatmaps, or multidimensional scaling configurations. See Boj and Grané (2024) <doi:10.1016/j.seps.2024.101992>.

The df2yaml aims to simplify the process of converting dataframe to YAML <https://yaml.org/>. The dataframe with multiple key columns and one value column will be converted to the multi-level hierarchy.

This package provides functions for discordant kinship modeling (and other sibling-based quasi-experimental designs). Contains data restructuring functions and functions for generating biometrically informed data for kin pairs. See [Garrison and Rodgers, 2016 <doi:10.1016/j.intell.2016.08.008>], [Sims, Trattner, and Garrison, 2024 <doi:10.3389/fpsyg.2024.1430978>] for empirical examples, and [Garrison and colleagues for theoretical work <doi:10.1101/2025.08.25.25334395>].

This package implements maximum likelihood methods for evaluating the durability of vaccine efficacy in a randomized, placebo-controlled clinical trial with staggered enrollment of participants and potential crossover of placebo recipients before the end of the trial. Lin, D. Y., Zeng, D., and Gilbert, P. B. (2021) <doi:10.1093/cid/ciab226> and Lin, D. Y., Gu, Y., Zeng, D., Janes, H. E., and Gilbert, P. B. (2021) <doi:10.1093/cid/ciab630>.

Gives you the ability to use arbitrary Docker images (including custom ones) to process Rmarkdown code chunks.

This package provides the mathematical model described by "Serostatus Testing & Dengue Vaccine Cost-Benefit Thresholds" in <doi:10.1098/rsif.2019.0234>. Using the functions in the package, that analysis can be repeated using sample life histories, either synthesized from local seroprevalence data using other functions in this package (as in the manuscript) or from some other source. The package provides a vignette which walks through the analysis in the publication, as well as a function to generate a project skeleton for such an analysis.