Used in testing if the indirect effect from linear regression mediation analysis is equal to 0. Includes established methods such as the Sobel Test, Joint Significant test (maxP), and tests based off the distribution of the Product or Normal Random Variables. Additionally, this package adds more powerful tests based on Intersection-Union theory. These tests are the S-Test, the ps-test, and the ascending squares test. These new methods are uniformly more powerful than maxP, which is more powerful than Sobel and less anti-conservative than the Product of Normal Random Variables. These methods are explored by Kidd and Lin, (2024) <doi:10.1007/s12561-023-09386-6> and Kidd et al., (2025) <doi:10.1007/s10260-024-00777-7>.

This package provides a component-based reactive UI framework for Shiny that binds reactive values directly to DOM attributes, enabling fine-grained updates without re-rendering or update*Input callbacks.

This package implements inequality constrained inference. This includes parameter estimation in normal (linear) models under linear equality and inequality constraints, as well as normal likelihood ratio tests involving inequality-constrained hypotheses. For inequality-constrained linear models, averaging over R-squared for different orderings of regressors is also included.

Starting from user-supplied institutional data, these scripts transform, aggregate, and reshape the information to produce key-value pair data files that are able to be uploaded to IPEDS (Integrated Postsecondary Education Data System) through their submission portal <https://surveys.nces.ed.gov/ipeds/>. Starting data specifications can be found in the vignettes. Final files are saved locally to a location of the user's choice. User-friendly readable files can also be produced for purposes of data review and validation.

Estimates weights to make a continuous-valued exposure statistically independent of a vector of pre-treatment covariates using the method proposed in Huling, Greifer, and Chen (2021) <arxiv:2107.07086>.

Enables the user to find the country, region, district, city, coordinates, zip code, time zone, ISP, domain name, connection type, area code, weather, Mobile Country Codes (MCC), Mobile Network Code (MNC), mobile brand name, elevation, usage type, address type, IAB category and Autonomous system number (ASN) that any IP address or hostname originates from. Supported IPv4 and IPv6. Please visit <https://www.ip2location.com> to learn more. You may also want to visit <https://lite.ip2location.com> for free database download. This package requires IP2Location Python module. At the terminal, please run pip install IP2Location to install the module.

R dependency injection framework. Dependency injection allows a program design to follow the dependency inversion principle. The user delegates to external code (the injector) the responsibility of providing its dependencies. This separates the responsibilities of use and construction.

This package provides tools for estimating incidence from biomarker data in cross- sectional surveys, and for calibrating tests for recent infection. Implements and extends the method of Kassanjee et al. (2012) <doi:10.1097/EDE.0b013e3182576c07>.

This package provides an R version of the InterVA4 software (<http://www.interva.net>) for coding cause of death from verbal autopsies. It also provides simple graphical representation of individual and population level statistics.

Decomposition of income inequality by groups formed of individuals possessing similar characteristics (e.g., sex, education, age) and their income sources at the same time. Decomposition of the Theil index is based on Giammatteo, M. (2007) <https://www.lisdatacenter.org/wps/liswps/466.pdf>. Decomposition of the squared coefficient of variation is based on Garcia-Penalosa, C., & Orgiazzi, E. (2013) <doi:10.1111/roiw.12054>.

Network functionalities specialized for data generated from input-output tables.

This package provides a integrated variance correlation is proposed to measure the dependence between a categorical or continuous random variable and a continuous random variable or vector. This package is designed to estimate the new correlation coefficient with parametric and nonparametric approaches. Test of independence for different problems can also be implemented via the new correlation coefficient with this package.

Implementation of tandem clustering with invariant coordinate selection with different scatter matrices and several choices for the selection of components as described in Alfons, A., Archimbaud, A., Nordhausen, K.and Ruiz-Gazen, A. (2024) <doi:10.1016/j.ecosta.2024.03.002>.

This package provides functions to support the ICES Transparent Assessment Framework <https://taf.ices.dk> to organize data, methods, and results used in ICES assessments. ICES is an organization facilitating international collaboration in marine science.

The itdr() routine allows for the estimation of sufficient dimension reduction subspaces in univariate regression such as the central mean subspace or central subspace in regression. This is achieved using Fourier transformation methods proposed by Zhu and Zeng (2006) <doi:10.1198/016214506000000140>, convolution transformation methods proposed by Zeng and Zhu (2010) <doi:10.1016/j.jmva.2009.08.004>, and iterative Hessian transformation methods proposed by Cook and Li (2002) <doi:10.1214/aos/1021379861>. Additionally, mitdr() function provides optimal estimators for sufficient dimension reduction subspaces in multivariate regression by optimizing a discrepancy function using a Fourier transform approach proposed by Weng and Yin (2022) <doi:10.5705/ss.202020.0312>, and selects the sufficient variables using Fourier transform sparse inverse regression estimators proposed by Weng (2022) <doi:10.1016/j.csda.2021.107380>.

This package provides a collection of functions that facilitate computational steps related to advice for fisheries management, according to ICES guidelines. These include methods for calculating reference points and model diagnostics.

This package provides a suite of functions for conducting and interpreting analysis of statistical interaction in regression models that was formerly part of the jtools package. Functionality includes visualization of two- and three-way interactions among continuous and/or categorical variables as well as calculation of "simple slopes" and Johnson-Neyman intervals (see e.g., Bauer & Curran, 2005 <doi:10.1207/s15327906mbr4003_5>). These capabilities are implemented for generalized linear models in addition to the standard linear regression context.

Expands iNEXT to include the estimation of sample completeness and evenness. The package provides simple functions to perform the following four-step biodiversity analysis: STEP 1: Assessment of sample completeness profiles. STEP 2a: Analysis of size-based rarefaction and extrapolation sampling curves to determine whether the asymptotic diversity can be accurately estimated. STEP 2b: Comparison of the observed and the estimated asymptotic diversity profiles. STEP 3: Analysis of non-asymptotic coverage-based rarefaction and extrapolation sampling curves. STEP 4: Assessment of evenness profiles. The analyses in STEPs 2a, 2b and STEP 3 are mainly based on the previous iNEXT package. Refer to the iNEXT package for details. This package is mainly focusing on the computation for STEPs 1 and 4. See Chao et al. (2020) <doi:10.1111/1440-1703.12102> for statistical background.

This package provides functions to simulate baseline characteristics, reconstruct overall survival data from published Kaplan-Meier curves, and generate publication-ready tables and forest plots reproducing the IMpower133 clinical trial results (Horn et al., 2018, <doi:10.1056/NEJMoa1809064>). The IPD reconstruction method is based on Liu et al.(2021, <doi:10.1186/s12874-021-01308-8>).

Estimation of joint models for multivariate longitudinal markers (with various distributions available) and survival outcomes (possibly accounting for competing risks) with Integrated Nested Laplace Approximations (INLA). The flexible and user friendly function joint() facilitates the use of the fast and reliable inference technique implemented in the INLA package for joint modeling. More details are given in the help page of the joint() function (accessible via ?joint in the R console) and the vignette associated to the joint() function (accessible via vignette("INLAjoint") in the R console).

This package provides functions to estimate the probability to receive the observed treatment, based on individual characteristics. The inverse of these probabilities can be used as weights when estimating causal effects from observational data via marginal structural models. Both point treatment situations and longitudinal studies can be analysed. The same functions can be used to correct for informative censoring.

Plot idiograms of karyotypes, plasmids, circular chr. having a set of data.frames for chromosome data and optionally mark data. Two styles of chromosomes can be used: without or with visible chromatids. Supports micrometers, cM and Mb or any unit. Three styles of centromeres are available: triangle, rounded and inProtein; and six styles of marks are available: square (squareLeft), dots, cM (cMLeft), cenStyle, upArrow (downArrow), exProtein (inProtein); its legend (label) can be drawn inline or to the right of karyotypes. Idiograms can also be plotted in concentric circles. It is possible to calculate chromosome indices by Levan et al. (1964) <doi:10.1111/j.1601-5223.1964.tb01953.x>, karyotype indices of Watanabe et al. (1999) <doi:10.1007/PL00013869> and Romero-Zarco (1986) <doi:10.2307/1221906> and classify chromosomes by morphology Guerra (1986) and Levan et al. (1964).

This package provides a toolbox for constructing potential landscapes for Ising networks. The parameters of the networks can be directly supplied by users or estimated by the IsingFit package by van Borkulo and Epskamp (2016) <https://CRAN.R-project.org/package=IsingFit> from empirical data. The Ising model's Boltzmann distribution is preserved for the potential landscape function. The landscape functions can be used for quantifying and visualizing the stability of network states, as well as visualizing the simulation process.

This package provides a collection of datasets containing a variety of in vitro toxicokinetic measurements including -- but not limited to -- chemical fraction unbound in the presence of plasma (f_up), intrinsic hepatic clearance (Clint, uL/min/million hepatocytes), and membrane permeability for oral absorption (Caco2). The datasets provided by the package were processed and analyzed with the companion invitroTKstats package.