This package provides a suite of tools for estimating, assessing model fit, simulating from, and visualizing location dependent marked point processes characterized by regularity in the pattern. You provide a reference marked point process, a set of raster images containing location specific covariates, and select the estimation algorithm and type of mark model. ldmppr estimates the process and mark models and allows you to check the appropriateness of the model using a variety of diagnostic tools. Once a satisfactory model fit is obtained, you can simulate from the model and visualize the results. Documentation for the package ldmppr is available in the form of a vignette.

Four measures of linkage disequilibrium are provided: the usual r^2 measure, the r^2_S measure (r^2 corrected by the structure sample), the r^2_V (r^2 corrected by the relatedness of genotyped individuals), the r^2_VS measure (r^2 corrected by both the relatedness of genotyped individuals and the structure of the sample).

The primary purpose of lavaan.mi is to extend the functionality of the R package lavaan', which implements structural equation modeling (SEM). When incomplete data have been multiply imputed, the imputed data sets can be analyzed by lavaan using complete-data estimation methods, but results must be pooled across imputations (Rubin, 1987, <doi:10.1002/9780470316696>). The lavaan.mi package automates the pooling of point and standard-error estimates, as well as a variety of test statistics, using a familiar interface that allows users to fit an SEM to multiple imputations as they would to a single data set using the lavaan package.

Runtime for serving containers that can execute R code on the AWS Lambda serverless compute service <https://aws.amazon.com/lambda/>. Provides the necessary functionality for handling the various endpoints required for accepting new input and sending responses.

This package provides a diverse collection of georeferenced and spatial datasets from different domains including urban studies, housing markets, environmental monitoring, transportation, and socio-economic indicators. The package consolidates datasets from multiple open sources such as Kaggle, chopin, spData, adespatial, and bivariateLeaflet. It is designed for researchers, analysts, and educators interested in spatial analysis, geostatistics, and geographic data visualization. The datasets include point patterns, polygons, socio-economic data frames, and network-like structures, allowing flexible exploration of geospatial phenomena.

High dimensional longitudinal data analysis with Markov Chain Monte Carlo(MCMC). Currently support mixed effect regression with or without missing observations by considering covariance structures. It provides estimates by missing at random and missing not at random assumptions. In this R package, we present Bayesian approaches that statisticians and clinical researchers can easily use. The functions methodology is based on the book "Bayesian Approaches in Oncology Using R and OpenBUGS" by Bhattacharjee A (2020) <doi:10.1201/9780429329449-14>.

This package provides a wrapper around the LIBLINEAR C/C++ library for machine learning (available at <https://www.csie.ntu.edu.tw/~cjlin/liblinear/>). LIBLINEAR is a simple library for solving large-scale regularized linear classification and regression. It currently supports L2-regularized classification (such as logistic regression, L2-loss linear SVM and L1-loss linear SVM) as well as L1-regularized classification (such as L2-loss linear SVM and logistic regression) and L2-regularized support vector regression (with L1- or L2-loss). The main features of LiblineaR include multi-class classification (one-vs-the rest, and Crammer & Singer method), cross validation for model selection, probability estimates (logistic regression only) or weights for unbalanced data. The estimation of the models is particularly fast as compared to other libraries.

This package provides access to the LDlink API (<https://ldlink.nih.gov/?tab=apiaccess>) using the R console. This programmatic access facilitates researchers who are interested in performing batch queries in 1000 Genomes Project (2015) <doi:10.1038/nature15393> data using LDlink'. LDlink is an interactive and powerful suite of web-based tools for querying germline variants in human population groups of interest. For more details, please see Machiela et al. (2015) <doi:10.1093/bioinformatics/btv402>.

Estimates marginal likelihood from a posterior sample using the method described in Wang et al. (2023) <doi:10.1093/sysbio/syad007>, which does not require evaluation of any additional points and requires only the log of the unnormalized posterior density for each sampled parameter vector.

This package contains a collection of useful functions for basic data computation and manipulation, wrapper functions for generating ggplot2 graphics, including statistical model diagnostic plots, methods for computing statistical models quality measures (such as AIC, BIC, r squared, root mean squared error) and general utilities.

This package provides an extension to factors called lfactor that are similar to factors but allows users to refer to lfactor levels by either the level or the label.

An implementation of a computational framework for performing robust structured regression with the L2 criterion from Chi and Chi (2021+). Improvements using the majorization-minimization (MM) principle from Liu, Chi, and Lange (2022+) added in Version 2.0.

Routines to perform large scale regression. Linear, logistic, and Poisson regressions are supported. Large scale regression efficiently fits models where a small number of covariates are changing and the subjects have complete data. A genome wide association study would be an example.

Estimates a lognormal-Pareto mixture by means of the Expectation-Conditional-Maximization-Either algorithm and by maximizing the profile likelihood function. A likelihood ratio test for discriminating between lognormal and Pareto tail is also implemented. See Bee, M. (2022) <doi:10.1007/s11634-022-00497-4>.

Use the leaflet-timeline plugin with a leaflet widget to add an interactive slider with play, pause, and step buttons to explore temporal geographic spatial data changes.

Time series analysis based on lambda transformer and variational seq2seq, built on Torch'.

Local partial likelihood estimation by Fan, Lin and Zhou(2006)<doi:10.1214/009053605000000796> and simultaneous confidence band is a set of tools to test the covariates-biomarker interaction for survival data. Test for the covariates-biomarker interaction using the bootstrap method and the asymptotic method with simultaneous confidence band (Liu, Jiang and Chen (2015)<doi:10.1002/sim.6563>).

Clustering or classification of longitudinal data based on a mixture of multivariate t or Gaussian distributions with a Cholesky-decomposed covariance structure. Details in McNicholas and Murphy (2010) <doi:10.1002/cjs.10047> and McNicholas and Subedi (2012) <doi:10.1016/j.jspi.2011.11.026>.

Computes comorbidity indices and combined frailty scores for multiple ICD coding systems, including ICD-10-CA, ICD-10-CM, and ICD-11. The package provides tools to preprocess episode data, map diagnosis codes to chronic categories, propagate conditions across episodes, and generate comorbidity and frailty measures. The methods implemented are original to this package and were developed by the authors for research applications; a manuscript describing the methodology is currently in preparation.

Publication-ready regional gene locus plots similar to those produced by the web interface LocusZoom <https://my.locuszoom.org>, but running locally in R. Genetic or genomic data with gene annotation tracks are plotted via R base graphics, ggplot2 or plotly', allowing flexibility and easy customisation including laying out multiple locus plots on the same page. It uses the LDlink API <https://ldlink.nih.gov/?tab=apiaccess> to query linkage disequilibrium data from the 1000 Genomes Project and can overlay this on plots <doi:10.1093/bioadv/vbaf006>.

Dimensionality reduction techniques for binary data including logistic PCA.

This package creates a consensus genetic map by merging linkage maps from different populations. The software uses linear programming (LP) to efficiently minimize the mean absolute error between the consensus map and the linkage maps. This minimization is performed subject to linear inequality constraints that ensure the ordering of the markers in the linkage maps is preserved. When marker order is inconsistent between linkage maps, a minimum set of ordinal constraints is deleted to resolve the conflicts.

This package provides functions that compute the lattice-based density and regression estimators for two-dimensional regions with irregular boundaries and holes. The density estimation technique is described in Barry and McIntyre (2011) <doi:10.1016/j.ecolmodel.2011.02.016>, while the non-parametric regression technique is described in McIntyre and Barry (2018) <doi:10.1080/10618600.2017.1375935>.

Converts table-like objects to stand-alone PDF or PNG. Can be used to embed tables and arbitrary content in PDF or Word documents. Provides a low-level R interface for creating LaTeX code, e.g. command() and a high-level interface for creating PDF documents, e.g. as.pdf.data.frame(). Extensive customization is available via mid-level functions, e.g. as.tabular(). See also package?latexpdf'. Support for PNG is experimental; see as.png.data.frame'. Adapted from metrumrg <https://r-forge.r-project.org/R/?group_id=1215>. Requires a compatible installation of pdflatex', e.g. <https://miktex.org/>.