This package provides tools for the analysis of psychophysical data in R. This package allows to estimate the Point of Subjective Equivalence (PSE) and the Just Noticeable Difference (JND), either from a psychometric function or from a Generalized Linear Mixed Model (GLMM). Additionally, the package allows plotting the fitted models and the response data, simulating psychometric functions of different shapes, and simulating data sets. For a description of the use of GLMMs applied to psychophysical data, refer to Moscatelli et al. (2012).

Two functions for simulating the solution of initial value problems of the form g'(x) = G(x, g) with g(x0) = g0. One is an acceptance-rejection method. The other is a method based on the Mean Value Theorem.

It finds Orthogonal Data Projections with Maximal Skewness. The first data projection in the output is the most skewed among all linear data projections. The second data projection in the output is the most skewed among all data projections orthogonal to the first one, and so on.

This package performs maximum likelihood estimation for finite mixture models for families including Normal, Weibull, Gamma and Lognormal by using EM algorithm, together with Newton-Raphson algorithm or bisection method when necessary. It also conducts mixture model selection by using information criteria or bootstrap likelihood ratio test. The data used for mixture model fitting can be raw data or binned data. The model fitting process is accelerated by using R package Rcpp'.

Make all elements of a character vector unique. Differs from make.unique by starting at 1 and allowing users to customise suffix format.

Simulating data and fitting multi-species N-mixture models using nimble'. Includes features for handling zero-inflation and temporal correlation, Bayesian inference, model diagnostics, parameter estimation, and predictive checks. Designed for ecological studies with zero-altered or time-series data. Mimnagh, N., Parnell, A., Prado, E., & Moral, R. A. (2022) <doi:10.1007/s10651-022-00542-7>. Royle, J. A. (2004) <doi:10.1111/j.0006-341X.2004.00142.x>.

This package performs meta-analysis and meta-regression using standard and robust methods with confidence intervals based on the profile likelihood. Robust methods are based on alternative distributions for the random effect, either the t-distribution (Lee and Thompson, 2008 <doi:10.1002/sim.2897> or Baker and Jackson, 2008 <doi:10.1007/s10729-007-9041-8>) or mixtures of normals (Beath, 2014 <doi:10.1002/jrsm.1114>).

Compare microbial co-occurrence networks created from trans_network class of microeco package <https://github.com/ChiLiubio/microeco>. This package is the extension of trans_network class of microeco package and especially useful when different networks are constructed and analyzed simultaneously.

Package to carry out merged block randomization (Van der Pas (2019), <doi:10.1177/1740774519827957>), a restricted randomization method designed for small clinical trials (at most 100 subjects) or trials with small strata, for example in multicentre trials. It can be used for more than two groups or unequal randomization ratios.

Estimation and comparison of the performances of diagnostic tests in multi-reader multi-case studies where true case statuses (or ground truths) are known and one or more readers provide test ratings for multiple cases. Reader performance metrics are provided for area under and expected utility of ROC curves, likelihood ratio of positive or negative tests, and sensitivity and specificity. ROC curves can be estimated empirically or with binormal or binormal likelihood-ratio models. Statistical comparisons of diagnostic tests are based on the ANOVA model of Obuchowski-Rockette and the unified framework of Hillis (2005) <doi:10.1002/sim.2024>. The ANOVA can be conducted with data from a full factorial, nested, or partially paired study design; with random or fixed readers or cases; and covariances estimated with the DeLong method, jackknifing, or an unbiased method. Smith and Hillis (2020) <doi:10.1117/12.2549075>.

This package provides tools for cleaning, processing, and preparing microbiome sequencing data (e.g., 16S rRNA) for downstream analysis. Supports CSV, TXT, and Excel file formats. The main function, ezclean(), automates microbiome data transformation, including format validation, transposition, numeric conversion, and metadata integration. It also handles taxonomic levels efficiently, resolves duplicated taxa entries, and outputs a well-structured, analysis-ready dataset. The companion functions ezstat() run statistical tests and summarize results, while ezviz() produces publication-ready visualizations.

There are two functions-meta2d and meta3d for detecting rhythmic signals from time-series datasets. For analyzing time-series datasets without individual information, meta2d is suggested, which could incorporates multiple methods from ARSER, JTK_CYCLE and Lomb-Scargle in the detection of interested rhythms. For analyzing time-series datasets with individual information, meta3d is suggested, which takes use of any one of these three methods to analyze time-series data individual by individual and gives out integrated values based on analysis result of each individual.

This package provides a toolbox to train a single sample classifier that uses in-sample feature relationships. The relationships are represented as feature1 < feature2 (e.g. gene1 < gene2). We provide two options to go with. First is based on switchBox package which uses Top-score pairs algorithm. Second is a novel implementation based on random forest algorithm. For simple problems we recommend to use one-vs-rest using TSP option due to its simplicity and for being easy to interpret. For complex problems RF performs better. Both lines filter the features first then combine the filtered features to make the list of all the possible rules (i.e. rule1: feature1 < feature2, rule2: feature1 < feature3, etc...). Then the list of rules will be filtered and the most important and informative rules will be kept. The informative rules will be assembled in an one-vs-rest model or in an RF model. We provide a detailed description with each function in this package to explain the filtration and training methodology in each line. Reference: Marzouka & Eriksson (2021) <doi:10.1093/bioinformatics/btab088>.

Tool for easy prior construction and visualization. It helps to formulates joint prior distributions for variance parameters in latent Gaussian models. The resulting prior is robust and can be created in an intuitive way. A graphical user interface (GUI) can be used to choose the joint prior, where the user can click through the model and select priors. An extensive guide is available in the GUI. The package allows for direct inference with the specified model and prior. Using a hierarchical variance decomposition, we formulate a joint variance prior that takes the whole model structure into account. In this way, existing knowledge can intuitively be incorporated at the level it applies to. Alternatively, one can use independent variance priors for each model components in the latent Gaussian model. Details can be found in the accompanying scientific paper: Hem, Fuglstad, Riebler (2024, Journal of Statistical Software, <doi:10.18637/jss.v110.i03>).

Predictive multivariate modelling for metabolomics. Types: Classification and regression. Methods: Partial Least Squares, Random Forest ans Elastic Net Data structures: Paired and unpaired Validation: repeated double cross-validation (Westerhuis et al. (2008)<doi:10.1007/s11306-007-0099-6>, Filzmoser et al. (2009)<doi:10.1002/cem.1225>) Variable selection: Performed internally, through tuning in the inner cross-validation loop.

This package provides tools that facilitate ordinary differential equation (ODE) modeling in R'. This package allows one to perform simulations for ODE models that are encoded in the GNU MCSim model specification language (Bois, 2009) <doi:10.1093/bioinformatics/btp162> using ODE solvers from the R package deSolve (Soetaert et al., 2010) <doi:10.18637/jss.v033.i09>.

Create dummy variables from categorical data. This package can convert categorical data (factor and ordered) into dummy variables and handle multiple columns simultaneously. This package enables to select whether a dummy variable for base group is included (for principal component analysis/factor analysis) or excluded (for regression analysis) by an option. makedummies function accepts data.frame', matrix', and tbl (tibble) class (by tibble package). matrix class data is automatically converted to data.frame class.

Multivariate Surrogate Synchrony ('mvSUSY') estimates the synchrony within datasets that contain more than two time series. mvSUSY was developed from Surrogate Synchrony ('SUSY') with respect to implementing surrogate controls, and extends synchrony estimation to multivariate data. mvSUSY works as described in Meier & Tschacher (2021).

This package contains auxiliary routines for influx software. This packages is not intended to be used directly. Influx was published here: Sokol et al. (2012) <doi:10.1093/bioinformatics/btr716>.

Cancer cells accumulate DNA mutations as result of DNA damage and DNA repair processes. This computational framework is aimed at deciphering DNA mutational signatures operating in cancer. The framework includes modules that support raw data import and processing, mutational signature extraction, and results interpretation and visualization. The framework accepts widely used file formats storing information about DNA variants, such as Variant Call Format files. The framework performs Non-Negative Matrix Factorization to extract mutational signatures explaining the observed set of DNA mutations. Bootstrapping is performed as part of the analysis. The framework supports parallelization and is optimized for use on multi-core systems. The software was described by Fantini D et al (2020) <doi:10.1038/s41598-020-75062-0> and is based on a custom R-based implementation of the original MATLAB WTSI framework by Alexandrov LB et al (2013) <doi:10.1016/j.celrep.2012.12.008>.

Analyze multilevel networks as described in Lazega et al (2008) <doi:10.1016/j.socnet.2008.02.001> and in Lazega and Snijders (2016, ISBN:978-3-319-24520-1). The package was developed essentially as an extension to igraph'.

The chi-squared test for goodness of fit and independence test.

Computes regression deletion diagnostics for multivariate linear models and provides some associated diagnostic plots. The diagnostic measures include hat-values (leverages), generalized Cook's distance, and generalized squared studentized residuals. Several types of plots to detect influential observations are provided.

Facilitates creation and manipulation of metric graphs, such as street or river networks. Further facilitates operations and visualizations of data on metric graphs, and the creation of a large class of random fields and stochastic partial differential equations on such spaces. These random fields can be used for simulation, prediction and inference. In particular, linear mixed effects models including random field components can be fitted to data based on computationally efficient sparse matrix representations. Interfaces to the R packages INLA and inlabru are also provided, which facilitate working with Bayesian statistical models on metric graphs. The main references for the methods are Bolin, Simas and Wallin (2024) <doi:10.3150/23-BEJ1647>, Bolin, Kovacs, Kumar and Simas (2023) <doi:10.1090/mcom/3929> and Bolin, Simas and Wallin (2023) <doi:10.48550/arXiv.2304.03190> and <doi:10.48550/arXiv.2304.10372>.