This package provides methods for controlling the median of the false discovery proportion (mFDP). Depending on the method, simultaneous or non-simultaneous inference is provided. The methods take a vector of p-values or test statistics as input.

Constructs multi-resolution thin-plate spline basis functions on the sphere for use in spatial regression and large-scale spatial prediction problems. Implements the basis system described in Huang, Huang, and Ing (2025) "Multi-Resolution Spatial Methods on the Sphere: Efficient Prediction for Global Data", Environmetrics, <doi:10.1002/env.70092>. Heavy computations are written in C++ via Rcpp with optional OpenMP parallelism.

Age-specific mortality rates are estimated and projected using the Kannisto, Lee-Carter and related methods as described in Sevcikova et al. (2016) <doi:10.1007/978-3-319-26603-9_15>.

Extends the mlr3 ecosystem to functional analysis by adding support for irregular and regular functional data as defined in the tf package. The package provides PipeOps for preprocessing functional columns and for extracting scalar features, thereby allowing standard machine learning algorithms to be applied afterwards. Available operations include simple functional features such as the mean or maximum, smoothing, interpolation, flattening, and functional PCA'.

This package contains a set of tools for constructing and coercing into and from the "mdate" class. This date class implements ISO 8601-2:2019(E) and allows regular dates to be annotated to express unspecified date components, approximate or uncertain date components, date ranges, and sets of dates. This is useful for describing and analysing temporal information, whether historical or recent, where date precision may vary.

Create an interactive table of descriptive statistics in HTML. This table is typically used for exploratory analysis in a clinical study (referred to as Table 1').

Perform missing value imputation for biological data using the random forest algorithm, the imputation aim to keep the original mean and standard deviation consistent after imputation.

Lightweight maps of mammals of the world. These maps are a comprehensive collection of maps aligned with the Mammal Diversity Database taxonomy of the American Society of Mammalogists. They are generated at low resolution for easy access, consultation and manipulation in shapefile format. The package connects to a binary backup hosted in the Digital Ocean cloud service and allows individual or batch download of any mammal species in the mdd taxonomy by providing the scientific species name.

Two functions for simulating the solution of initial value problems of the form g'(x) = G(x, g) with g(x0) = g0. One is an acceptance-rejection method. The other is a method based on the Mean Value Theorem.

This package provides a unified toolkit for classical test theory (CTT) item analysis of multiple-choice test data, including item difficulty (p-value), item discrimination (point-biserial correlation and upper-lower 27-percent discrimination index), per-distractor analysis (frequency, proportion, and discrimination), and Haladyna's distractor efficiency. A wrapper function returns a tidy mcq_analysis object with print, plot (difficulty-discrimination scatter), and APA-style table methods for direct inclusion in journal manuscripts. Implemented in pure R with no compiled code and minimal dependencies.

Quantify exposure-outcome causal effects with adjustment for multiple biases. The functions can simultaneously adjust for any combination of uncontrolled confounding, exposure/outcome misclassification, and selection bias. The underlying method generalizes the combination of inverse probability of selection weighting with predictive value weighting. Simultaneous multi-bias analysis can be used to enhance the validity and transparency of real-world evidence obtained from observational, longitudinal studies. Based on the work from Paul Brendel, Aracelis Torres, and Onyebuchi Arah (2023) <doi:10.1093/ije/dyad001>.

Machine learning method specifically designed for pre-miRNA prediction. It takes advantage of unlabeled sequences to improve the prediction rates even when there are just a few positive examples, when the negative examples are unreliable or are not good representatives of its class. Furthermore, the method can automatically search for negative examples if the user is unable to provide them. MiRNAss can find a good boundary to divide the pre-miRNAs from other groups of sequences; it automatically optimizes the threshold that defines the classes boundaries, and thus, it is robust to high class imbalance. Each step of the method is scalable and can handle large volumes of data.

Mixed models for repeated measures (MMRM) are a popular choice for analyzing longitudinal continuous outcomes in randomized clinical trials and beyond; see Cnaan, Laird and Slasor (1997) <doi:10.1002/(SICI)1097-0258(19971030)16:20%3C2349::AID-SIM667%3E3.0.CO;2-E> for a tutorial and Mallinckrodt, Lane, Schnell, Peng and Mancuso (2008) <doi:10.1177/009286150804200402> for a review. This package implements MMRM based on the marginal linear model without random effects using Template Model Builder ('TMB') which enables fast and robust model fitting. Users can specify a variety of covariance matrices, weight observations, fit models with restricted or standard maximum likelihood inference, perform hypothesis testing with Satterthwaite or Kenward-Roger adjustment, and extract least square means estimates by using emmeans'.

Summarize multiple biomarker responses of aquatic organisms to contaminants using Cliffâ s delta, as described in Pham & Sokolova (2023) <doi:10.1002/ieam.4676>.

The effects of the site may severely bias the accuracy of a multisite machine-learning model, even if the analysts removed them when fitting the model in the training set and applying the model in the test set (Solanes et al., Neuroimage 2023, 265:119800). This simple R package estimates the accuracy of a multisite machine-learning model unbiasedly, as described in (Solanes et al., Psychiatry Research: Neuroimaging 2021, 314:111313). It currently supports the estimation of sensitivity, specificity, balanced accuracy (for binary or multinomial variables), the area under the curve, correlation, mean squarer error, and hazard ratio for binomial, multinomial, gaussian, and survival (time-to-event) outcomes.

Developed for the following tasks. 1- simulating realizations from the canonical, restricted, and unrestricted finite mixture models. 2- Monte Carlo approximation for density function of the finite mixture models. 3- Monte Carlo approximation for the observed Fisher information matrix, asymptotic standard error, and the corresponding confidence intervals for parameters of the mixture models sing the method proposed by Basford et al. (1997) <https://espace.library.uq.edu.au/view/UQ:57525>.

Various utilities to manipulate multivariate polynomials. The package is almost completely superceded by the spray and mvp packages, which are much more efficient.

This package provides a color palette generator inspired by Mexican politics, with colors ranging from red on the left to gray in the middle and green on the right. Palette options range from only a few colors to several colors, but with discrete and continuous options to offer greatest flexibility to the user. This package allows for a range of applications, from mapping brief discrete scales (e.g., four colors for Morena, PRI, and PAN) to continuous interpolated arrays including dozens of shades graded from red to green.

The target of margaret is help to extract data from Minciencias to analyze scientific production in Colombia.

BEAST2 (<https://www.beast2.org>) is a widely used Bayesian phylogenetic tool, that uses DNA/RNA/protein data and many model priors to create a posterior of jointly estimated phylogenies and parameters. BEAST2 is commonly accompanied by BEAUti 2 (<https://www.beast2.org>), which, among others, allows one to install BEAST2 package. This package allows to work with BEAST2 packages from R'.

Estimation, inference and forecasting using the Bayesian approach for multivariate threshold autoregressive (TAR) models in which the distribution used to describe the noise process belongs to the class of Gaussian variance mixtures.

There are an increasing number of mega-phylogenies available nowadays, with many of them being sets of thousands of posterior distribution phylogenies. For ecological studies, we may need to randomly select many such posterior phylogenies to conduct analyses. This data package serves this purpose by providing a small number (100 or 50) of randomly selected posterior phylogenies (if available) so that we can readily use them for our downstream analyses without repeating the downloading and selecting processes.

Optimization algorithms implemented in R, including conjugate gradient (CG), Broyden-Fletcher-Goldfarb-Shanno (BFGS) and the limited memory BFGS (L-BFGS) methods. Most internal parameters can be set through the call interface. The solvers hold up quite well for higher-dimensional problems.

Handy helper package for cross-referencing lake identifiers among different data sets in the Midwestern United States. There are multiple different state, regional, and federal agencies that have different identifiers on lakes. This package helps you to go between them.