Efficient procedure for fitting regularization paths between L1 and L0, using the MC+ penalty of Zhang, C.H. (2010)<doi:10.1214/09-AOS729>. Implements the methodology described in Mazumder, Friedman and Hastie (2011) <DOI: 10.1198/jasa.2011.tm09738>. Sparsenet computes the regularization surface over both the family parameter and the tuning parameter by coordinate descent.

This package implements the "shrinkage t" statistic introduced in Opgen-Rhein and Strimmer (2007) <DOI:10.2202/1544-6115.1252> and a shrinkage estimate of the "correlation-adjusted t-score" (CAT score) described in Zuber and Strimmer (2009) <DOI:10.1093/bioinformatics/btp460>. It also offers a convenient interface to a number of other regularized t-statistics commonly employed in high-dimensional case-control studies.

This package implements a regularization method for cumulative link models using the Smooth-Effect-on-Response Penalty (SERP). This method allows flexible modeling of ordinal data by enabling a smooth transition from a general cumulative link model to a simplified version of the same model. As the tuning parameter increases from zero to infinity, the subject-specific effects for each variable converge to a single global effect. The approach addresses common issues in cumulative link models, such as parameter unidentifiability and numerical instability, by maximizing a penalized log-likelihood instead of the standard non-penalized version. Fitting is performed using a modified Newton's method. Additionally, the package includes various model performance metrics and descriptive tools. For details on the implemented penalty method, see Ugba (2021) <doi:10.21105/joss.03705> and Ugba et al. (2021) <doi:10.3390/stats4030037>.

Estimate necessary sample sizes for comparing the location of data from two groups or categories when the distribution of the data is skewed. The package offers a non-parametric method for a Wilcoxon Mann-Whitney test of location shift as well as methods for several generalized linear models, for instance, Gamma regression.

This package provides a general purpose simulation-based power analysis API for routine and customized simulation experimental designs. The package focuses exclusively on Monte Carlo simulation experiment variants of (expected) prospective power analyses, criterion analyses, compromise analyses, sensitivity analyses, and a priori/post-hoc analyses. The default simulation experiment functions defined within the package provide stochastic variants of the power analysis subroutines in G*Power 3.1 (Faul, Erdfelder, Buchner, and Lang, 2009) <doi:10.3758/brm.41.4.1149>, along with various other parametric and non-parametric power analysis applications (e.g., mediation analyses) and support for Bayesian power analysis by way of Bayes factors or posterior probability evaluations. Additional functions for building empirical power curves, reanalyzing simulation information, and for increasing the precision of the resulting power estimates are also included, each of which utilize similar API structures. For further details see the associated publication in Chalmers (2025) <doi:10.3758/s13428-025-02787-z>.

Maximum likelihood tools to fit and compare models of species abundance distributions and of species rank-abundance distributions.

This package provides a computing tool is developed to automated identify somatic mutation-driven immune cells. The operation modes including: i) inferring the relative abundance matrix of tumor-infiltrating immune cells and integrating it with a particular gene mutation status, ii) detecting differential immune cells with respect to the gene mutation status and converting the abundance matrix of significant differential immune cell into two binary matrices (one for up-regulated and one for down-regulated), iii) identifying somatic mutation-driven immune cells by comparing the gene mutation status with each immune cell in the binary matrices across all samples, and iv) visualization of immune cell abundance of samples in different mutation status..

Detect libraries used in a project and automatically create software bibliographies in PDF', Word', Rmarkdown', and BibTeX formats.

Generate programmable surveys using markdown and R code chunks. Surveys are composed of two files: a survey.qmd Quarto file defining the survey content (pages, questions, etc), and an app.R file defining a shiny app with global settings (libraries, database configuration, etc.) and server configuration options (e.g., conditional skipping / display, etc.). Survey data collected from respondents is stored in a PostgreSQL database. Features include controls for conditional skip logic (skip to a page based on an answer to a question), conditional display logic (display a question based on an answer to a question), a customizable progress bar, and a wide variety of question types, including multiple choice (single choice and multiple choices), select, text, numeric, multiple choice buttons, text area, and dates. Because the surveys render into a shiny app, designers can also leverage the reactive capabilities of shiny to create dynamic and interactive surveys.

This package creates stratum orthogonal arrays (also known as strong orthogonal arrays). These are arrays with more levels per column than the typical orthogonal array, and whose low order projections behave like orthogonal arrays, when collapsing levels to coarser strata. Details are described in Groemping (2022) "A unifying implementation of stratum (aka strong) orthogonal arrays" <http://www1.bht-berlin.de/FB_II/reports/Report-2022-002.pdf>.

Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) <doi:10.1002/sim.8295>. The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated.

Some R functions, such as optim(), require a function its gradient passed as separate arguments. When these are expensive to calculate it may be much faster to calculate the function (fn) and gradient (gr) together since they often share many calculations (chain rule). This package allows the user to pass in a single function that returns both the function and gradient, then splits (hence splitfngr') them so the results can be accessed separately. The functions provided allow this to be done with any number of functions/values, not just for functions and gradients.

Perform spatial analysis on network. Implement several methods for spatial analysis on network: Network Kernel Density estimation, building of spatial matrices based on network distance ('listw objects from spdep package), K functions estimation for point pattern analysis on network, k nearest neighbours on network, reachable area calculation, and graph generation References: Okabe et al (2019) <doi:10.1080/13658810802475491>; Okabe et al (2012, ISBN:978-0470770818);Baddeley et al (2015, ISBN:9781482210200).

RegLog system provides a set of shiny modules to handle register procedure for your users, alongside with login, edit credentials and password reset functionality. It provides support for popular SQL databases and optionally googlesheet-based database for easy setup. For email sending it provides support for emayili and gmailr backends. Architecture makes customizing usability pretty straightforward. The authentication system created with shiny.reglog is designed to be optional: user don't need to be logged-in to access your application, but when logged-in the user data can be used to read from and write to relational databases.

Produce small area population estimates by fitting census data to survey data.

Construct subtests from a pool of items by using ant-colony-optimization, genetic algorithms, brute force, or random sampling. Schultze (2017) <doi:10.17169/refubium-622>.

Scale alignment is a new procedure for rescaling dimensions of between-items multidimensional Rasch family models so that dimensions scores can be compared directly (Feuerstahler & Wilson, 2019; under review) <doi:10.1111/jedm.12209>. This package includes functions for implementing delta-dimensional alignment (DDA) and logistic regression alignment (LRA) for dichotomous or polytomous data. This function also includes a wrapper for models fit using the TAM package.

Calculates the sup MZ value to detect the unknown structural break points under Heteroskedasticity as given in Ahmed et al. (2017) (<DOI: 10.1080/03610926.2016.1235200>).

Data processing and visualizations for rodent vocalizations exported from DeepSqueak'. These functions are compatible with the SqueakR Shiny Dashboard, which can be used to visualize experimental results and analyses.

Convenient tools for exchanging files securely from within R. By encrypting the content safe passage of files (shipment) can be provided by common but insecure carriers such as ftp and email. Based on asymmetric cryptography no management of shared secrets is needed to make a secure shipment as long as authentic public keys are available. Public keys used for secure shipments may also be obtained from external providers as part of the overall process. Transportation of files will require that relevant services such as ftp and email servers are available.

Routines for creating, manipulating, and performing Bayesian inference about Gaussian processes in one and two dimensions using the Fourier basis approximation: simulation and plotting of processes, calculation of coefficient variances, calculation of process density, coefficient proposals (for use in MCMC). It uses R environments to store GP objects as references/pointers.

This package provides functions to implement the stability controlled quasi-experiment (SCQE) approach to study the effects of newly adopted treatments that were not assigned at random. This package contains tools to help users avoid making statistical assumptions that rely on infeasible assumptions. Methods developed in Hazlett (2019) <doi:10.1002/sim.8717>.

This package provides some basic routines for simulating a clinical trial. The primary intent is to provide some tools to generate trial simulations for trials with time to event outcomes. Piecewise exponential failure rates and piecewise constant enrollment rates are the underlying mechanism used to simulate a broad range of scenarios such as those presented in Lin et al. (2020) <doi:10.1080/19466315.2019.1697738>. However, the basic generation of data is done using pipes to allow maximum flexibility for users to meet different needs.

This package implements data-driven identification methods for structural vector autoregressive (SVAR) models as described in Lange et al. (2021) <doi:10.18637/jss.v097.i05>. Based on an existing VAR model object (provided by e.g. VAR() from the vars package), the structural impact matrix is obtained via data-driven identification techniques (i.e. changes in volatility (Rigobon, R. (2003) <doi:10.1162/003465303772815727>), patterns of GARCH (Normadin, M., Phaneuf, L. (2004) <doi:10.1016/j.jmoneco.2003.11.002>), independent component analysis (Matteson, D. S, Tsay, R. S., (2013) <doi:10.1080/01621459.2016.1150851>), least dependent innovations (Herwartz, H., Ploedt, M., (2016) <doi:10.1016/j.jimonfin.2015.11.001>), smooth transition in variances (Luetkepohl, H., Netsunajev, A. (2017) <doi:10.1016/j.jedc.2017.09.001>) or non-Gaussian maximum likelihood (Lanne, M., Meitz, M., Saikkonen, P. (2017) <doi:10.1016/j.jeconom.2016.06.002>)).