This package performs binary classification via Group Method of Data Handling (GMDH) - type neural network algorithms. There exist two main algorithms available in GMDH() and dceGMDH() functions. GMDH() performs classification via GMDH algorithm for a binary response and returns important variables. dceGMDH() performs classification via diverse classifiers ensemble based on GMDH (dce-GMDH) algorithm. Also, the package produces a well-formatted table of descriptives for a binary response. Moreover, it produces confusion matrix, its related statistics and scatter plot (2D and 3D) with classification labels of binary classes to assess the prediction performance. All GMDH2 functions are designed for a binary response (Dag et al., 2019, <https://download.atlantis-press.com/article/125911202.pdf>).

Pleiotropy-informed significance analysis of genome-wide association studies (GWAS) with surrogate functional false discovery rates (sfFDR). The sfFDR framework adapts the fFDR to leverage informative data from multiple sets of GWAS summary statistics to increase power in study while accommodating for linkage disequilibrium. sfFDR provides estimates of key FDR quantities in a significance analysis such as the functional local FDR and q-value, and uses these estimates to derive a functional p-value for type I error rate control and a functional local Bayes factor for post-GWAS analyses (e.g., fine mapping and colocalization). The sfFDR framework is described in Bass and Wallace (2024) <doi:10.1101/2024.09.24.24314276>.

This package provides a set of tools to perform Ecological Niche Modeling with presence-absence data. It includes algorithms for data partitioning, model fitting, calibration, evaluation, selection, and prediction. Other functions help to explore signals of ecological niche using univariate and multivariate analyses, and model features such as variable response curves and variable importance. Unique characteristics of this package are the ability to exclude models with concave quadratic responses, and the option to clamp model predictions to specific variables. These tools are implemented following principles proposed in Cobos et al., (2022) <doi:10.17161/bi.v17i.15985>, Cobos et al., (2019) <doi:10.7717/peerj.6281>, and Peterson et al., (2008) <doi:10.1016/j.ecolmodel.2007.11.008>.

The accurate annotation of genes and Quantitative Trait Loci (QTLs) located within candidate markers and/or regions (haplotypes, windows, CNVs, etc) is a crucial step the most common genomic analyses performed in livestock, such as Genome-Wide Association Studies or transcriptomics. The Genomic Annotation in Livestock for positional candidate LOci (GALLO) is an R package designed to provide an intuitive and straightforward environment to annotate positional candidate genes and QTLs from high-throughput genetic studies in livestock. Moreover, GALLO allows the graphical visualization of gene and QTL annotation results, data comparison among different grouping factors (e.g., methods, breeds, tissues, statistical models, studies, etc.), and QTL enrichment in different livestock species including cattle, pigs, sheep, and chicken, among others.

This package is a implementation of biclustering ensemble method MoSBi (Molecular signature Identification from Biclustering). MoSBi provides standardized interfaces for biclustering results and can combine their results with a multi-algorithm ensemble approach to compute robust ensemble biclusters on molecular omics data. This is done by computing similarity networks of biclusters and filtering for overlaps using a custom error model. After that, the louvain modularity it used to extract bicluster communities from the similarity network, which can then be converted to ensemble biclusters. Additionally, MoSBi includes several network visualization methods to give an intuitive and scalable overview of the results. MoSBi comes with several biclustering algorithms, but can be easily extended to new biclustering algorithms.

Evaluates land suitability for different crops production. The package is based on the Food and Agriculture Organization (FAO) and the International Rice Research Institute (IRRI) methodology for land evaluation. Development of ALUES is inspired by similar tool for land evaluation, Land Use Suitability Evaluation Tool (LUSET). The package uses fuzzy logic approach to evaluate land suitability of a particular area based on inputs such as rainfall, temperature, topography, and soil properties. The membership functions used for fuzzy modeling are the following: Triangular, Trapezoidal and Gaussian. The methods for computing the overall suitability of a particular area are also included, and these are the Minimum, Maximum and Average. Finally, ALUES is a highly optimized library with core algorithms written in C++.

This package provides a method that estimates an IV-optimal individualized treatment rule. An individualized treatment rule is said to be IV-optimal if it minimizes the maximum risk with respect to the putative IV and the set of IV identification assumptions. Please refer to <arXiv:2002.02579> for more details on the methodology and some theory underpinning the method. Function IV-PILE() uses functions in the package locClass'. Package locClass can be accessed and installed from the R-Forge repository via the following link: <https://r-forge.r-project.org/projects/locclass/>. Alternatively, one can install the package by entering the following in R: install.packages("locClass", repos="<http://R-Forge.R-project.org>")'.

This package provides a comprehensive suite of tools for managing, processing, and analyzing data from the IFCB. I R FlowCytobot ('iRfcb') supports quality control, geospatial analysis, and preparation of IFCB data for publication in databases like <https://www.gbif.org>, <https://www.obis.org>, <https://emodnet.ec.europa.eu/en>, <https://shark.smhi.se/>, and <https://www.ecotaxa.org>. The package integrates with the MATLAB ifcb-analysis tool, which is described in Sosik and Olson (2007) <doi:10.4319/lom.2007.5.204>, and provides features for working with raw, manually classified, and machine learningâ classified image datasets. Key functionalities include image extraction, particle size distribution analysis, taxonomic data handling, and biomass concentration calculations, essential for plankton research.

This package provides a Modern and Flexible Neo4J Driver, allowing you to query data on a Neo4J server and handle the results in R. It's modern in the sense it provides a driver that can be easily integrated in a data analysis workflow, especially by providing an API working smoothly with other data analysis and graph packages. It's flexible in the way it returns the results, by trying to stay as close as possible to the way Neo4J returns data. That way, you have the control over the way you will compute the results. At the same time, the result is not too complex, so that the "heavy lifting" of data wrangling is not left to the user.

This package provides a collection of miscellaneous functions for copying objects to the clipboard ('Copy'); manipulating strings ('concat', mgsub', trim', verlan'); loading or showing packages ('library_with_dep', require_with_dep', sessionPackages'); creating or testing for named lists ('nlist', as.nlist', is.nlist'), formulas ('is.formula'), empty objects ('as.empty', is.empty'), whole numbers ('as.wholenumber', is.wholenumber'); testing for equality ('almost.equal', almost.zero') and computing uniqueness ('almost.unique'); getting modified versions of usual functions ('rle2', sumNA'); making a pause or a stop ('pause', stopif'); converting into a function ('as.fun'); providing a C like ternary operator ('condition %?% true %:% false'); finding packages and functions ('get_all_pkgs', get_all_funs'); and others ('erase', %nin%', unwhich', top', bot', normalize').

This package provides interface to the MATLAB toolbox Flexible Statistical Data Analysis (FSDA) which is comprehensive and computationally efficient software package for robust statistics in regression, multivariate and categorical data analysis. The current R version implements tools for regression: (forward search, S- and MM-estimation, least trimmed squares (LTS) and least median of squares (LMS)), for multivariate analysis (forward search, S- and MM-estimation), for cluster analysis and cluster-wise regression. The distinctive feature of our package is the possibility of monitoring the statistics of interest as a function of breakdown point, efficiency or subset size, depending on the estimator. This is accompanied by a rich set of graphical features, such as dynamic brushing, linking, particularly useful for exploratory data analysis.

This package provides a model that provides researchers with a powerful tool for the classification and study of native corn by aiding in the identification of racial complexes which are fundamental to Mexico's agriculture and culture. This package has been developed based on data collected by "Proyecto Global de Maà ces Nativos México", which has conducted exhaustive surveys across the country to document the qualitative and quantitative characteristics of different types of native maize. The trained model uses a robust and diverse dataset, enabling it to achieve an 80% accuracy in classifying maize racial complexes. The characteristics included in the analysis comprise geographic location, grain and cob colors, as well as various physical measurements, such as lengths and widths.

Fits Stable Isotope Mixing Models (SIMMs) and is meant as a longer term replacement to the previous widely-used package SIAR. SIMMs are used to infer dietary proportions of organisms consuming various food sources from observations on the stable isotope values taken from the organisms tissue samples. However SIMMs can also be used in other scenarios, such as in sediment mixing or the composition of fatty acids. The main functions are simmr_load() and simmr_mcmc(). The two vignettes contain a quick start and a full listing of all the features. The methods used are detailed in the papers Parnell et al 2010 <doi:10.1371/journal.pone.0009672>, and Parnell et al 2013 <doi:10.1002/env.2221>.

Run mixed-effects models that include weights at every level. The WeMix package fits a weighted mixed model, also known as a multilevel, mixed, or hierarchical linear model (HLM). The weights could be inverse selection probabilities, such as those developed for an education survey where schools are sampled probabilistically, and then students inside of those schools are sampled probabilistically. Although mixed-effects models are already available in R, WeMix is unique in implementing methods for mixed models using weights at multiple levels. Both linear and logit models are supported. Models may have up to three levels. Random effects are estimated using the PIRLS algorithm from lme4pureR (Walker and Bates (2013) <https://github.com/lme4/lme4pureR>).

Performs unconditional exact tests and power calculations for 2x2 contingency tables. For comparing two independent proportions, performs Barnard's test (1945) using the original CSM test (Barnard (1947)), using Fisher's p-value referred to as Boschloo's test (1970), or using a Z-statistic (Suissa and Shuster (1985)). For comparing two binary proportions, performs unconditional exact test using McNemar's Z-statistic (Berger and Sidik (2003)), using McNemar's Z-statistic with continuity correction, or using CSM test. Calculates confidence intervals for the difference in proportion.

Includes the reference implementation of Genie - a hierarchical clustering algorithm that links two point groups in such a way that an inequity measure (namely, the Gini index) of the cluster sizes does not significantly increase above a given threshold. This method most often outperforms many other data segmentation approaches in terms of clustering quality as tested on a wide range of benchmark datasets. At the same time, Genie retains the high speed of the single linkage approach, therefore it is also suitable for analysing larger data sets. For more details see (Gagolewski et al. 2016 <DOI:10.1016/j.ins.2016.05.003>). For an even faster and more feature-rich implementation, including, amongst others, noise point detection, see the genieclust package.

Data and utilities for estimating pediatric blood pressure percentiles by sex, age, and optionally height (stature) as described in Martin et.al. (2022) <doi:10.1001/jamanetworkopen.2022.36918>. Blood pressure percentiles for children under one year of age come from Gemelli et.al. (1990) <doi:10.1007/BF02171556>. Estimates of blood pressure percentiles for children at least one year of age are informed by data from the National Heart, Lung, and Blood Institute (NHLBI) and the Centers for Disease Control and Prevention (CDC) <doi:10.1542/peds.2009-2107C> or from Lo et.al. (2013) <doi:10.1542/peds.2012-1292>. The flowchart for selecting the informing data source comes from Martin et.al. (2022) <doi:10.1542/hpeds.2021-005998>.

Implementation of SPECS, your favourite Single-Equation Penalized Error-Correction Selector developed in Smeekes and Wijler (2021) <doi:10.1016/j.jeconom.2020.07.021>. SPECS provides a fully automated estimation procedure for large and potentially (co)integrated datasets. The dataset in levels is converted to a conditional error-correction model, either by the user or by means of the functions included in this package, and various specialised forms of penalized regression can be applied to the model. Automated options for initializing and selecting a sequence of penalties, as well as the construction of penalty weights via an initial estimator, are available. Moreover, the user may choose from a number of pre-specified deterministic configurations to further simplify the model building process.

This package provides tools for creating and working with survey replicate weights, extending functionality of the survey package from Lumley (2004) <doi:10.18637/jss.v009.i08>. Implements bootstrap methods for complex surveys, including the generalized survey bootstrap as described by Beaumont and Patak (2012) <doi:10.1111/j.1751-5823.2011.00166.x>. Methods are provided for applying nonresponse adjustments to both full-sample and replicate weights as described by Rust and Rao (1996) <doi:10.1177/096228029600500305>. Implements methods for sample-based calibration described by Opsomer and Erciulescu (2021) <https://www150.statcan.gc.ca/n1/pub/12-001-x/2021002/article/00006-eng.htm>. Diagnostic functions are included to compare weights and weighted estimates from different sets of replicate weights.

Gcrma adjusts for background intensities in Affymetrix array data which include optical noise and non-specific binding (NSB). The main function gcrma converts background adjusted probe intensities to expression measures using the same normalization and summarization methods as a Robust Multiarray Average (RMA). Gcrma uses probe sequence information to estimate probe affinity to NSB. The sequence information is summarized in a more complex way than the simple GC content. Instead, the base types (A, T, G or C) at each position along the probe determine the affinity of each probe. The parameters of the position-specific base contributions to the probe affinity is estimated in an NSB experiment in which only NSB but no gene-specific binding is expected.

This package provides a Cairo graphics device that can be use to create high-quality vector (PDF, PostScript and SVG) and bitmap output (PNG,JPEG,TIFF), and high-quality rendering in displays (X11 and Win32). Since it uses the same back-end for all output, copying across formats is WYSIWYG. Files are created without the dependence on X11 or other external programs. This device supports alpha channel (semi-transparent drawing) and resulting images can contain transparent and semi-transparent regions. It is ideal for use in server environments (file output) and as a replacement for other devices that don't have Cairo's capabilities such as alpha support or anti-aliasing. Backends are modular such that any subset of backends is supported.

Construction and smart selection of Gaussian process models for analysis of computer experiments with emphasis on treatment of functional inputs that are regularly sampled. This package offers: (i) flexible modeling of functional-input regression problems through the fairly general Gaussian process model; (ii) built-in dimension reduction for functional inputs; (iii) heuristic optimization of the structural parameters of the model (e.g., active inputs, kernel function, type of distance). An in-depth tutorial in the use of funGp is provided in Betancourt et al. (2024) <doi:10.18637/jss.v109.i05> and Metamodeling background is provided in Betancourt et al. (2020) <doi:10.1016/j.ress.2020.106870>. The algorithm for structural parameter optimization is described in <https://hal.science/hal-02532713>.

Includes the ga.lts() function that estimates LTS (Least Trimmed Squares) parameters using genetic algorithms and C-steps. ga.lts() constructs a genetic algorithm to form a basic subset and iterates C-steps as defined in Rousseeuw and van-Driessen (2006) to calculate the cost value of the LTS criterion. OLS (Ordinary Least Squares) regression is known to be sensitive to outliers. A single outlying observation can change the values of estimated parameters. LTS is a resistant estimator even the number of outliers is up to half of the data. This package is for estimating the LTS parameters with lower bias and variance in a reasonable time. Version >=1.3 includes the function medmad for fast outlier detection in linear regression.

Identifying maturation stages across young athletes is paramount for talent identification. Furthermore, the concept of biobanding, or grouping of athletes based on their biological development, instead of their chronological age, has been widely researched. The goal of this package is to help professionals working in the field of strength & conditioning and talent ID obtain common maturation metrics and as well as to quickly visualize this information via several plotting options. For the methods behind the computed maturation metrics implemented in this package refer to Khamis, H. J., & Roche, A. F. (1994) <https://pubmed.ncbi.nlm.nih.gov/7936860/>, Mirwald, R.L et al., (2002) <https://pubmed.ncbi.nlm.nih.gov/11932580/> and Cumming, Sean P. et al., (2017) <doi:10.1519/SSC.0000000000000281>.