Raw data downloaded from GEO for the compound LY294002. Raw data is from multiple platforms from Affymetrix and Illumina. This data is used to illustrate the cross-platform meta-analysis of microarray data using the crossmeta package.
Toolbox for larger-than-memory scientific computing and visualization, providing efficient out-of-core data structures using files or shared memory, for dense and sparse vectors, matrices, and arrays, with applications to nonuniformly sampled signals and images.
Assorted utilities for multi-modal analyses of single-cell datasets. Includes functions to combine multiple modalities for downstream analysis, perform MNN-based batch correction across multiple modalities, and to compute correlations between assay values for different modalities.
This package contains R functions to predict biological variables to from placnetal DNA methylation data generated from infinium arrays. This includes inferring ethnicity/ancestry, gestational age, and cell composition from placental DNA methylation array (450k/850k) data.
SIGHTS is a suite of normalization methods, statistical tests, and diagnostic graphical tools for high throughput screening (HTS) assays. HTS assays use microtitre plates to screen large libraries of compounds for their biological, chemical, or biochemical activity.
Simulation and pricing routines for rare-event options using Adaptive Multilevel Splitting and standard Monte Carlo under Black-Scholes and Heston models. Core routines are implemented in C++ via Rcpp and RcppArmadillo with lightweight R wrappers.
This package provides tools to read/write/publish metadata based on the Atom XML syndication format. This includes support of Dublin Core XML implementation, and a client to API(s) implementing the AtomPub - SWORD API specification.
Fit Bayesian Regression Additive Trees (BART) models to select true confounders from a large set of potential confounders and to estimate average treatment effect. For more information, see Kim et al. (2023) <doi:10.1111/biom.13833>.
Implementation of DetMCD, a new algorithm for robust and deterministic estimation of location and scatter. The benefits of robust and deterministic estimation are explained in Hubert, Rousseeuw and Verdonck (2012) <doi:10.1080/10618600.2012.672100>.
Leverages dplyr to process the calculations of a plot inside a database. This package provides helper functions that abstract the work at three levels: outputs a ggplot', outputs the calculations, outputs the formula needed to calculate bins.
This package provides a penalized/non-penalized implementation for dynamic regression in the presence of autocorrelated residuals (DREGAR) using iterative penalized/ordinary least squares. It applies Mallows CP, AIC, BIC and GCV to select the tuning parameters.
Measurement and partitioning of diversity, based on Tsallis entropy, following Marcon and Herault (2015) <doi:10.18637/jss.v067.i08>. divent provides functions to estimate alpha, beta and gamma diversity of communities, including phylogenetic and functional diversity.
This package provides a set of functions, which facilitates removing objects from an environment. It allows to delete objects specified with regular expression or with other conditions (e.g. if object is numeric), using one function call.
Detects sustained change in digital bio-marker data using simultaneous confidence bands. Accounts for noise using an auto-regressive model. Based on Buehlmann (1998) "Sieve bootstrap for smoothing in nonstationary time series" <doi:10.1214/aos/1030563978>.
This package provides ggsnap(), which saves a ggplot2 plot to disk in a + chain, acting as a thin, chainable wrapper around ggplot2::ggsave(). Can be called multiple times in a chain to save different snapshots.
Fit Bayesian compartmental infection models (such as susceptible-infected-recovered and multi-compartment hidden Markov variants) from individual-level outcome data. Models are composed from infection-process and observation-process components and fit using Stan via rstan'.
New kernel-based test and fast tests for detecting change-points or changed-intervals where the distributions abruptly change. They work well particularly for high-dimensional data. Song, H. and Chen, H. (2022) <arXiv:2206.01853>.
Data sets in the book entitled "Multivariate Statistical Methods with R Applications", H.Bulut (2018). The book was published in Turkish and the original name of this book will be "R Uygulamalari ile Cok Degiskenli Istatistiksel Yontemler".
Mixtures of skewed and elliptical distributions are implemented using mixtures of multivariate skew power exponential and power exponential distributions, respectively. A generalized expectation-maximization framework is used for parameter estimation. See citation() for how to cite.
Perform flexible simulation studies using one or multiple computer cores. The package is set up to be usable on high-performance clusters in addition to being run locally (i.e., see the package vignettes for more information).
Homogeneity tests of the coefficients in panel data. Currently, only the Hsiao test for determining coefficient homogeneity between the panel data individuals is implemented, as described in Hsiao (2022), "Analysis of Panel Data" (<doi:10.1017/9781009057745>).
This function aims to calculate risk of developing cardiovascular disease of individual patients in next 10 years. This unofficial package was based on published open-sourced free risk prediction algorithm QRISK3-2017 <https://qrisk.org/src.php>.
Simultaneously infers state-dependent diversification across two or more states of a single or multiple traits while accounting for the role of a possible concealed trait. See Herrera-Alsina et al. (2019) <doi:10.1093/sysbio/syy057>.
Sequential Kalman filter for scalable online changepoint detection by temporally correlated data. It enables fast single and multiple change points with missing values. See the reference: Hanmo Li, Yuedong Wang, Mengyang Gu (2023), <arXiv:2310.18611>.