Analyse single case analyses against a control group. Its purpose is to provide a flexible, with good power and low first type error approach that can manage at the same time controls and patient's data. The use of Bayesian statistics allows to test both the alternative and null hypothesis. Scandola, M., & Romano, D. (2020, August 3). <doi:10.31234/osf.io/sajdq> Scandola, M., & Romano, D. (2021). <doi:10.1016/j.neuropsychologia.2021.107834>.

This package performs sensitivity analysis for the sharp null, attributable effects, and weak nulls in matched studies with continuous exposures and binary or continuous outcomes as described in Zhang, Small, Heng (2024) <doi:10.48550/arXiv.2401.06909> and Zhang, Heng (2024) <doi:10.48550/arXiv.2409.12848>. Two of the functions require installation of the Gurobi optimizer. Please see <https://docs.gurobi.com/current/#refman/ins_the_r_package.html> for guidance.

This package provides a comprehensive toolkit for analyzing microscopy data output from QuPath software. Provides functionality for automated data processing, metadata extraction, and statistical analysis of imaging results. The methodology implemented in this package is based on Labrosse et al. (2024) <doi:10.1016/j.xpro.2024.103274> "Protocol for quantifying drug sensitivity in 3D patient-derived ovarian cancer models", which describes the complete workflow for drug sensitivity analysis in patient-derived cancer models.

This package provides tools to estimate the genome size of polyploid species using k-mer frequencies. This package includes functions to process k-mer frequency data and perform genome size estimation by fitting k-mer frequencies with a normal distribution model. It supports handling of complex polyploid genomes and offers various options for customizing the estimation process. The basic method findGSE is detailed in Sun, Hequan, et al. (2018) <doi:10.1093/bioinformatics/btx637>.

This package provides a minimal set of routines to calculate the Grantham distance <doi:10.1126/science.185.4154.862>. The Grantham distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

Set of tools for reading, writing and transforming spatial and seasonal data, model selection and specific statistical tests for ecologists. It includes functions to interpolate regular positions of points between landmarks, to discretize polylines into regular point positions, link distant observations to points and convert a bounding box in a spatial object. It also provides miscellaneous functions for field ecologists such as spatial statistics and inference on diversity indexes, writing data.frame with Chinese characters.

Maximum likelihood estimation of the parameters of matrix and 3rd-order tensor normal distributions with unstructured factor variance covariance matrices, two procedures, and for unbiased modified likelihood ratio testing of simple and double separability for variance-covariance structures, two procedures. References: Dutilleul P. (1999) <doi:10.1080/00949659908811970>, Manceur AM, Dutilleul P. (2013) <doi:10.1016/j.cam.2012.09.017>, and Manceur AM, Dutilleul P. (2013) <doi:10.1016/j.spl.2012.10.020>.

Estimates the population average controlled difference for a given outcome between levels of a binary treatment, exposure, or other group membership variable of interest for clustered, stratified survey samples where sample selection depends on the comparison group. Provides three methods for estimation, namely outcome modeling and two factorizations of inverse probability weighting. Under stronger assumptions, these methods estimate the causal population average treatment effect. Salerno et al., (2024) <doi:10.48550/arXiv.2406.19597>.

This package provides functions and utilities to perform Statistical Analyses in the Six Sigma way. Through the DMAIC cycle (Define, Measure, Analyze, Improve, Control), you can manage several Quality Management studies: Gage R&R, Capability Analysis, Control Charts, Loss Function Analysis, etc. Data frames used in the books "Six Sigma with R" [ISBN 978-1-4614-3652-2] and "Quality Control with R" [ISBN 978-3-319-24046-6], are also included in the package.

R-based access to a large set of data variables relevant to forest ecology in British Columbia (BC), Canada. Layers are in raster format at 100m resolution in the BC Albers projection, hosted at the Federated Research Data Repository (FRDR) with <doi:10.20383/101.0283>. The collection includes: elevation; biogeoclimatic zone; wildfire; cutblocks; forest attributes from Hansen et al. (2013) <doi:10.1139/cjfr-2013-0401> and Beaudoin et al. (2017) <doi:10.1139/cjfr-2017-0184>; and rasterized Forest Insect and Disease Survey (FIDS) maps for a number of insect pest species, all covering the period 2001-2018. Users supply a polygon or point location in the province of BC, and rasterbc will download the overlapping raster tiles hosted at FRDR, merging them as needed and returning the result in R as a SpatRaster object. Metadata associated with these layers, and code for downloading them from their original sources can be found in the github repository <https://github.com/deankoch/rasterbc_src>.

RNA-sense tool compares RNA-seq time curves in two experimental conditions, i.e. wild-type and mutant, and works in three steps. At Step 1, it builds expression profile for each transcript in one condition (i.e. wild-type) and tests if the transcript abundance grows or decays significantly. Dynamic transcripts are then sorted to non-overlapping groups (time profiles) by the time point of switch up or down. At Step 2, RNA-sense outputs the groups of differentially expressed transcripts, which are up- or downregulated in the mutant compared to the wild-type at each time point. At Step 3, Correlations (Fisher's exact test) between the outputs of Step 1 (switch up- and switch down- time profile groups) and the outputs of Step2 (differentially expressed transcript groups) are calculated. The results of the correlation analysis are printed as two-dimensional color plot, with time profiles and differential expression groups at y- and x-axis, respectively, and facilitates the biological interpretation of the data.

This package provides a set of convenient functions for calculating sun-related information, including the sun's position (elevation and azimuth), and the times of sunrise, sunset, solar noon, and twilight for any given geographical location on Earth. These calculations are based on equations provided by the National Oceanic & Atmospheric Administration (NOAA) as described in "Astronomical Algorithms" by Jean Meeus (1991). A resource for researchers and professionals working in fields such as climatology, biology, and renewable energy.

Designed to help health economic modellers when building and reviewing models. The visualisation functions allow users to more easily review the network of functions in a project, and get lay summaries of them. The asserts included are intended to check for common errors, thereby freeing up time for modellers to focus on tests specific to the individual model in development or review. For more details see Smith and colleagues (2024)<doi:10.12688/wellcomeopenres.23180.1>.

This package provides functions to get and download city bike data from the website and API service of each city bike service in Norway. The package aims to reduce time spent on getting Norwegian city bike data, and lower barriers to start analyzing it. The data is retrieved from Oslo City Bike, Bergen City Bike, and Trondheim City Bike. The data is made available under NLOD 2.0 <https://data.norge.no/nlod/en/2.0>.

Skinfold measurements is one of the most popular and practical methods for estimating percent body fat. Body composition is a term that describes the relative proportions of fat, bone, and muscle mass in the human body. Following the collection of skinfold measurements, regression analysis (a statistical procedure used to predict a dependent variable based on one or more independent or predictor variables) is used to estimate total percent body fat in humans. <doi:10.4324/9780203868744>.

This package implements the model-free multiscale idealisation approaches: Jump-Segmentation by MUltiResolution Filter (JSMURF), Hotz et al. (2013) <doi:10.1109/TNB.2013.2284063>, JUmp Local dEconvolution Segmentation filter (JULES), Pein et al. (2018) <doi:10.1109/TNB.2018.2845126>, and Heterogeneous Idealization by Local testing and DEconvolution (HILDE), Pein et al. (2021) <doi:10.1109/TNB.2020.3031202>. Further details on how to use them are given in the accompanying vignette.

The Large Language Model (LLM) represents a groundbreaking advancement in data science and programming, and also allows us to extend the world of R. A seamless interface for integrating the OpenAI Web APIs into R is provided in this package. This package leverages LLM-based AI techniques, enabling efficient knowledge discovery and data analysis. The previous functions such as seamless translation and image generation have been moved to other packages deepRstudio and stableDiffusion4R'.

Estimate one or two cutpoints of a metric or ordinal-scaled variable in the multivariable context of survival data or time-to-event data. Visualise the cutpoint estimation process using contour plots, index plots, and spline plots. It is also possible to estimate cutpoints based on the assumption of a U-shaped or inverted U-shaped relationship between the predictor and the hazard ratio. Govindarajulu, U., and Tarpey, T. (2022) <doi:10.1080/02664763.2020.1846690>.

This package performs parallel analysis (Timmerman & Lorenzo-Seva, 2011 <doi:10.1037/a0023353>) and hull method (Lorenzo-Seva, Timmerman, & Kiers, 2011 <doi:10.1080/00273171.2011.564527>) for assessing the dimensionality of a set of variables using minimum rank factor analysis (see ten Berge & Kiers, 1991 <doi:10.1007/BF02294464> for more information). The package also includes the option to compute minimum rank factor analysis by itself, as well as the greater lower bound calculation.

The Darwin Core data standard is widely used to share biodiversity information, most notably by the Global Biodiversity Information Facility and its partner nodes; but converting data to this standard can be tricky. galaxias is functionally similar to devtools', but with a focus on building Darwin Core Archives rather than R packages, enabling data to be shared and re-used with relative ease. For details see Wieczorek and colleagues (2012) <doi:10.1371/journal.pone.0029715>.

Reads data collected from wearable acceleratometers as used in sleep and physical activity research. Currently supports file formats: binary data from GENEActiv <https://activinsights.com/>, .bin-format from GENEA devices (not for sale), and .cwa-format from Axivity <https://axivity.com>. Further, it has functions for reading text files with epoch level aggregates from Actical', Fitbit', Actiwatch', ActiGraph', and PhilipsHealthBand'. Primarily designed to complement R package GGIR <https://CRAN.R-project.org/package=GGIR>.

This package provides complete detailed preprocessing of two-dimensional gas chromatogram (GCxGC) samples. Baseline correction, smoothing, peak detection, and peak alignment. Also provided are some analysis functions, such as finding extracted ion chromatograms, finding mass spectral data, targeted analysis, and nontargeted analysis with either the National Institute of Standards and Technology Mass Spectral Library or with the mass data. There are also several visualization methods provided for each step of the preprocessing and analysis.

Facilitate frequentist and Bayesian meta-analysis of diagnosis and prognosis research studies. It includes functions to summarize multiple estimates of prediction model discrimination and calibration performance (Debray et al., 2019) <doi:10.1177/0962280218785504>. It also includes functions to evaluate funnel plot asymmetry (Debray et al., 2018) <doi:10.1002/jrsm.1266>. Finally, the package provides functions for developing multivariable prediction models from datasets with clustering (de Jong et al., 2021) <doi:10.1002/sim.8981>.

This package provides a declarative language for specifying multilevel models, solving for population parameters based on specified variance-explained effect size measures, generating data, and conducting power analyses to determine sample size recommendations. The specification allows for any number of within-cluster effects, between-cluster effects, covariate effects at either level, and random coefficients. Moreover, the models do not assume orthogonal effects, and predictors can correlate at either level and accommodate models with multiple interaction effects.