Fast estimation of multinomial (MNL) and mixed logit (MXL) models in R. Models can be estimated using "Preference" space or "Willingness-to-pay" (WTP) space utility parameterizations. Weighted models can also be estimated. An option is available to run a parallelized multistart optimization loop with random starting points in each iteration, which is useful for non-convex problems like MXL models or models with WTP space utility parameterizations. The main optimization loop uses the nloptr package to minimize the negative log-likelihood function. Additional functions are available for computing and comparing WTP from both preference space and WTP space models and for predicting expected choices and choice probabilities for sets of alternatives based on an estimated model. Mixed logit models can include uncorrelated or correlated heterogeneity covariances and are estimated using maximum simulated likelihood based on the algorithms in Train (2009) <doi:10.1017/CBO9780511805271>. More details can be found in Helveston (2023) <doi:10.18637/jss.v105.i10>.

Build powerful, linked-view dashboards in shiny applications. With a declarative, one-line setup, you can create bidirectional links between interactive components. When a user interacts with one element (e.g., clicking a map marker), all linked components (such as DT tables or other charts) instantly update. Supports leaflet maps, DT tables, plotly charts, and spatial data via sf objects out-of-the-box, with an extensible API for custom components.

This package provides a single analysis path that includes distance-based ordination, global tests of any effect of the microbiome, and tests of the effects of individual taxa with false-discovery-rate (FDR) control. It accommodates both continuous and discrete covariates as well as interaction terms to be tested either singly or in combination, allows for adjustment of confounding covariates, and uses permutation-based p-values that can control for sample correlations. It can be applied to transformed data, and an omnibus test can combine results from analyses conducted on different transformation scales. It can also be used for testing presence-absence associations based on infinite number of rarefaction replicates, testing mediation effects of the microbiome, analyzing censored time-to-event outcomes, and for compositional analysis by fitting linear models to centered-log-ratio taxa count data.

This package provides a comprehensive analysis tool for metabolomics data. It consists a variety of functional modules, including several new modules: a pre-processing module for normalization and imputation, an exploratory data analysis module for dimension reduction and source of variation analysis, a classification module with the new deep-learning method and other machine-learning methods, a prognosis module with cox-PH and neural-network based Cox-nnet methods, and pathway analysis module to visualize the pathway and interpret metabolite-pathway relationships. References: H. Paul Benton <http://www.metabolomics-forum.com/index.php?topic=281.0> Jeff Xia <https://github.com/cangfengzhe/Metabo/blob/master/MetaboAnalyst/website/name_match.R> Travers Ching, Xun Zhu, Lana X. Garmire (2018) <doi:10.1371/journal.pcbi.1006076>.

Fit the log binomial regression model (LBM) by Exact method. Limited parameter space of LBM causes trouble to find admissible estimates and fail to converge when MLE is close to or on the boundary of space. Exact method utilizes the property of boundary vectors to re-parametrize the model without losing any information, and fits the model on the standard fitting algorithm with no convergence issues.

Read, register and compare point sets from single molecule localization microscopy.

This package provides flexible but lightweight logging facilities for R scripts. Supports priority levels for logs and messages, flagging messages, capturing script output, switching logs, and logging to files or connections.

The Gaussian location-scale regression model is a multi-predictor model with explanatory variables for the mean (= location) and the standard deviation (= scale) of a response variable. This package implements maximum likelihood and Markov chain Monte Carlo (MCMC) inference (using algorithms from Girolami and Calderhead (2011) <doi:10.1111/j.1467-9868.2010.00765.x> and Nesterov (2009) <doi:10.1007/s10107-007-0149-x>), a parametric bootstrap algorithm, and diagnostic plots for the model class.

This package implements the LS-PLS (least squares - partial least squares) method described in for instance Jørgensen, K., Segtnan, V. H., Thyholt, K., Næs, T. (2004) "A Comparison of Methods for Analysing Regression Models with Both Spectral and Designed Variables" Journal of Chemometrics, 18(10), 451--464, <doi:10.1002/cem.890>.

Allows to install the R languageserver with all dependencies into a separate library and use that independent installation automatically when R is instantiated as a language server process. Useful for making language server seamless to use without running into package version conflicts.

The landmark approach allows survival predictions to be updated dynamically as new measurements from an individual are recorded. The idea is to set predefined time points, known as "landmark times", and form a model at each landmark time using only the individuals in the risk set. This package allows the longitudinal data to be modelled either using the last observation carried forward or linear mixed effects modelling. There is also the option to model competing risks, either through cause-specific Cox regression or Fine-Gray regression. To find out more about the methods in this package, please see <https://isobelbarrott.github.io/Landmarking/articles/Landmarking>.

Managing and exploring parameter estimation results derived from Maximum Likelihood Estimation (MLE) using the likelihood package. It provides functions for organizing, visualizing, and summarizing MLE outcomes, streamlining statistical analysis workflows. By improving interpretation and facilitating model evaluation, it helps users gain deeper insights into parameter estimation and model fitting, making MLE result exploration more efficient and accessible. See Goffe et al. (1994) <doi:10.1016/0304-4076(94)90038-8> for details on MLE, and Canham and Uriarte (2006) <doi:10.1890/04-0657> for application of MLE using likelihood'.

Transforms away factors with many levels prior to doing an OLS. Useful for estimating linear models with multiple group fixed effects, and for estimating linear models which uses factors with many levels as pure control variables. See Gaure (2013) <doi:10.1016/j.csda.2013.03.024> Includes support for instrumental variables, conditional F statistics for weak instruments, robust and multi-way clustered standard errors, as well as limited mobility bias correction (Gaure 2014 <doi:10.1002/sta4.68>). Since version 3.0, it provides dedicated functions to estimate Poisson models.

New empirical Bayes methods aiming at analyzing the association of single nucleotide polymorphisms (SNPs) to some particular disease are implemented in this package. The package uses local false discovery rate (LFDR) estimates of SNPs within a sample population defined as a "reference class" and discovers if SNPs are associated with the corresponding disease. Although SNPs are used throughout this document, other biological data such as protein data and other gene data can be used. Karimnezhad, Ali and Bickel, D. R. (2016) <http://hdl.handle.net/10393/34889>.

The package converts R data onto input and data for LocalSolver, executes optimization and exposes optimization results as R data. LocalSolver (http://www.localsolver.com/) is an optimization engine developed by Innovation24 (http://www.innovation24.fr/). It is designed to solve large-scale mixed-variable non-convex optimization problems. The localsolver package is developed and maintained by WLOG Solutions (http://www.wlogsolutions.com/en/) in collaboration with Decision Support and Analysis Division at Warsaw School of Economics (http://www.sgh.waw.pl/en/).

This package provides easy access for sentiment lexicons for those who want to do text analysis in Portuguese texts. As of now, two Portuguese lexicons are available: SentiLex-PT02 and OpLexicon (v2.1 and v3.0).

Classical tests of goodness-of-fit aim to validate the conformity of a postulated model to the data under study. In their standard formulation, however, they do not allow exploring how the hypothesized model deviates from the truth nor do they provide any insight into how the rejected model could be improved to better fit the data. To overcome these shortcomings, we establish a comprehensive framework for goodness-of-fit which naturally integrates modeling, estimation, inference and graphics. In this package, the deviance tests and comparison density plots are performed to conduct the LP smoothed inference, where the letter L denotes nonparametric methods based on quantiles and P stands for polynomials. Simulations methods are used to perform variance estimation, inference and post-selection adjustments. Algeri S. and Zhang X. (2020) <arXiv:2005.13011>.

An implementation of logistic normal multinomial (LNM) clustering. It is an extension of LNM mixture model proposed by Fang and Subedi (2020) <arXiv:2011.06682>, and is designed for clustering compositional data. The package includes 3 extended models: LNM Factor Analyzer (LNM-FA), LNM Bicluster Mixture Model (LNM-BMM) and Penalized LNM Factor Analyzer (LNM-FA). There are several advantages of LNM models: 1. LNM provides more flexible covariance structure; 2. Factor analyzer can reduce the number of parameters to estimate; 3. Bicluster can simultaneously cluster subjects and taxa, and provides significant biological insights; 4. Penalty term allows sparse estimation in the covariance matrix. Details for model assumptions and interpretation can be found in papers: Tu and Subedi (2021) <arXiv:2101.01871> and Tu and Subedi (2022) <doi:10.1002/sam.11555>.

Exact significance tests for a changepoint in linear or multiple linear regression. Confidence regions with exact coverage probabilities for the changepoint. Based on Knowles, Siegmund and Zhang (1991) <doi:10.1093/biomet/78.1.15>.

This package provides a collection of colour palettes inspired by some of our dearest butterfly species. This package provides continuous and categorical palettes, including some colour blind friendly options.

Estimate haplotypic or composite pairwise linkage disequilibrium (LD) in polyploids, using either genotypes or genotype likelihoods. Support is provided to estimate the popular measures of LD: the LD coefficient D, the standardized LD coefficient D', and the Pearson correlation coefficient r. All estimates are returned with corresponding standard errors. These estimates and standard errors can then be used for shrinkage estimation. The main functions are ldfast(), ldest(), mldest(), sldest(), plot.lddf(), format_lddf(), and ldshrink(). Details of the methods are available in Gerard (2021a) <doi:10.1111/1755-0998.13349> and Gerard (2021b) <doi:10.1038/s41437-021-00462-5>.

This package provides functions to fit quantile regression models for hierarchical data (2-level nested designs) as described in Geraci and Bottai (2014, Statistics and Computing) <doi:10.1007/s11222-013-9381-9>. A vignette is given in Geraci (2014, Journal of Statistical Software) <doi:10.18637/jss.v057.i13> and included in the package documents. The packages also provides functions to fit quantile models for independent data and for count responses.

The main function of the package is to perform backward selection of fixed effects, forward fitting of the random effects, and post-hoc analysis using parallel capabilities. Other functionality includes the computation of ANOVAs with upper- or lower-bound p-values and R-squared values for each model term, model criticism plots, data trimming on model residuals, and data visualization. The data to run examples is contained in package LCF_data.

Random forests are a statistical learning method widely used in many areas of scientific research essentially for its ability to learn complex relationships between input and output variables and also its capacity to handle high-dimensional data. However, current random forests approaches are not flexible enough to handle longitudinal data. In this package, we propose a general approach of random forests for high-dimensional longitudinal data. It includes a flexible stochastic model which allows the covariance structure to vary over time. Furthermore, we introduce a new method which takes intra-individual covariance into consideration to build random forests. The method is fully detailled in Capitaine et.al. (2020) <doi:10.1177/0962280220946080> Random forests for high-dimensional longitudinal data.