This package provides methods for managing under- and over-enrollment in Simon's Two-Stage Design are offered by providing adaptive threshold adjustments and sample size recalibration. It also includes post-inference analysis tools to support clinical trial design and evaluation. The package is designed to enhance flexibility and accuracy in trial design, ensuring better outcomes in oncology and other clinical studies. Yunhe Liu, Haitao Pan (2024). Submitted.

This package provides tools for working with Type S (Sign) and Type M (Magnitude) errors, as proposed in Gelman and Tuerlinckx (2000) <doi:10.1007/s001800000040> and Gelman & Carlin (2014) <doi:10.1177/1745691614551642>. In addition to simply calculating the probability of Type S/M error, the package includes functions for calculating these errors across a variety of effect sizes for comparison, and recommended sample size given "tolerances" for Type S/M errors. To improve the speed of these calculations, closed forms solutions for the probability of a Type S/M error from Lu, Qiu, and Deng (2018) <doi:10.1111/bmsp.12132> are implemented. As of 1.0.0, this includes support only for simple research designs. See the package vignette for a fuller exposition on how Type S/M errors arise in research, and how to analyze them using the type of design analysis proposed in the above papers.

The cfToolsData package supplies the data for the cfTools package. It contains two pre-trained deep neural network (DNN) models for the cfSort function. Additionally, it includes the shape parameters of beta distribution characterizing methylation markers associated with four tumor types for the CancerDetector function, as well as the parameters characterizing methylation markers specific to 29 primary human tissue types for the cfDeconvolve function.

This package contains the data for the paper by L. David et al. in PNAS 2006 (PMID 16569694): 8 CEL files of Affymetrix genechips, an ExpressionSet object with the raw feature data, a probe annotation data structure for the chip and the yeast genome annotation (GFF file) that was used. In addition, some custom-written analysis functions are provided, as well as R scripts in the scripts directory.

Rank results by confident effect sizes, while maintaining False Discovery Rate and False Coverage-statement Rate control. Topconfects is an alternative presentation of TREAT results with improved usability, eliminating p-values and instead providing confidence bounds. The main application is differential gene expression analysis, providing genes ranked in order of confident log2 fold change, but it can be applied to any collection of effect sizes with associated standard errors.

Adaptive and Robust Transfer Learning (ART) is a flexible framework for transfer learning that integrates information from auxiliary data sources to improve model performance on primary tasks. It is designed to be robust against negative transfer by including the non-transfer model in the candidate pool, ensuring stable performance even when auxiliary datasets are less informative. See the paper, Wang, Wu, and Ye (2023) <doi:10.1002/sta4.582>.

Assignment of cell type labels to single-cell RNA sequencing (scRNA-seq) clusters is often a time-consuming process that involves manual inspection of the cluster marker genes complemented with a detailed literature search. This is especially challenging when unexpected or poorly described populations are present. The clustermole R package provides methods to query thousands of human and mouse cell identity markers sourced from a variety of databases.

This package provides a set of tools for evaluating clustering robustness using proportion of ambiguously clustered pairs (Senbabaoglu et al. (2014) <doi:10.1038/srep06207>), as well as similarity across methods and method stability using element-centric clustering comparison (Gates et al. (2019) <doi:10.1038/s41598-019-44892-y>). Additionally, this package enables stability-based parameter assessment for graph-based clustering pipelines typical in single-cell data analysis.

This package provides a collection of functions for computing fairness metrics for machine learning and statistical models, including confidence intervals for each metric. The package supports the evaluation of group-level fairness criterion commonly used in fairness research, particularly in healthcare for binary protected attributes. It is based on the overview of fairness in machine learning written by Gao et al (2024) <doi:10.48550/arXiv.2406.09307>.

Simplifies the process of creating essential visualizations in R, offering a range of plotting functions for common chart types like violin plots, pie charts, and histograms. With an intuitive interface, users can effortlessly customize colors, labels, and styles, making it an ideal tool for both beginners and experienced data analysts. Whether exploring datasets or producing quick visual summaries, this package provides a streamlined solution for fundamental graphics in R.

It predicts any attribute (categorical) given a set of input numeric predictor values. Note that only numeric input predictors should be given. The k value can be chosen according to accuracies provided. The attribute to be predicted can be selected from the dropdown provided (select categorical attribute). This is because categorical attributes cannot be given as inputs here. A handsontable is also provided to enter the input predictor values.

The provided package implements multiple contrast tests for functional data (Munko et al., 2023, <arXiv:2306.15259>). These procedures enable us to evaluate the overall hypothesis regarding equality, as well as specific hypotheses defined by contrasts. In particular, we can perform post hoc tests to examine particular comparisons of interest. Different experimental designs are supported, e.g., one-way and multi-way analysis of variance for functional data.

This package performs support vectors analysis for data sets with survival outcome. Three approaches are available in the package: The regression approach takes censoring into account when formulating the inequality constraints of the support vector problem. In the ranking approach, the inequality constraints set the objective to maximize the concordance index for comparable pairs of observations. The hybrid approach combines the regression and ranking constraints in the same model.

Asio is a cross-platform C++ library for network and low-level I/O programming that provides developers with a consistent asynchronous model using a modern C++ approach. It is also included in Boost but requires linking when used with Boost. Standalone it can be used header-only (provided a recent compiler). Asio is written and maintained by Christopher M. Kohlhoff, and released under the Boost Software License', Version 1.0.

An approach to filter out and/or identify phytoplankton cells from all particles measured via flow cytometry pigment and cell complexity information. It does this using a sequence of one-dimensional gates on pre-defined channels measuring certain pigmentation and complexity. The package is especially tuned for cyanobacteria, but will work fine for phytoplankton communities where there is at least one cell characteristic that differentiates every phytoplankton in the community.

This R package helps the user identify k-mers (e.g. di- or tri-nucleotides) present periodically in a set of genomic loci (typically regulatory elements). The functions of this package provide a straightforward approach to find periodic occurrences of k-mers in DNA sequences, such as regulatory elements. It is not aimed at identifying motifs separated by a conserved distance; for this type of analysis, please visit MEME website.

Tracking accrual in clinical trials is important for trial success. If accrual is too slow, the trial will take too long and be too expensive. If accrual is much faster than expected, time sensitive tasks such as the writing of statistical analysis plans might need to be rushed. accrualPlot provides functions to aid the tracking of accrual and predict when a trial will reach it's intended sample size.

Israeli baby names provided by Israel's Central Bureau of Statistics. The package contains only names used for at least 5 children in at least one gender and sector ("Jewish", "Muslim", "Christian", "Druze" and "Other"). Data was downloaded from: <https://www.cbs.gov.il/he/publications/LochutTlushim/2020/%D7%A9%D7%9E%D7%95%D7%AA-%D7%A4%D7%A8%D7%98%D7%99%D7%99%D7%9D.xlsx>.

An implementation of several functions for feature extraction in categorical time series datasets. Specifically, some features related to marginal distributions and serial dependence patterns can be computed. These features can be used to feed clustering and classification algorithms for categorical time series, among others. The package also includes some interesting datasets containing biological sequences. Practitioners from a broad variety of fields could benefit from the general framework provided by ctsfeatures'.

Offers various swiss maps as data frames and ggplot2 objects and gives the possibility to add layers of data on the maps. Data are publicly available from the swiss federal statistical office. In addition to the \codemaps2 object (a list of 8 swiss maps, at various levels), there are the data frames with the boundaries used to produce these maps (\codeshp_df, a list with 8 data frames).

The gasanalyzer R package offers methods for importing, preprocessing, and analyzing data related to photosynthetic characteristics (gas exchange, chlorophyll fluorescence and isotope ratios). It translates variable names into a standard format, and can recalculate derived, physiological quantities using imported or predefined equations. The package also allows users to assess the sensitivity of their results to different assumptions used in the calculations. See also Tholen (2024) <doi:10.1093/aobpla/plae035>.

This package provides matrix Gaussian mixture models, matrix transformation mixture models and their model-based clustering results. The parsimonious models of the mean matrices and variance covariance matrices are implemented with a total of 196 variations. For more information, please check: Xuwen Zhu, Shuchismita Sarkar, and Volodymyr Melnykov (2021), "MatTransMix: an R package for matrix model-based clustering and parsimonious mixture modeling", <doi:10.1007/s00357-021-09401-9>.

This package provides a latent variable model based on factor analytic and mixture of experts models, designed to infer food intake from multiple biomarkers data. The model is framed within a Bayesian hierarchical framework, which provides flexibility to adapt to different biomarker distributions and facilitates inference on food intake from biomarker data alone, along with the associated uncertainty. Details are in D'Angelo, et al. (2020) <arXiv:2006.02995>.

Greedy Bayesian algorithm to fit the noisy stochastic block model to an observed sparse graph. Moreover, a graph inference procedure to recover Gaussian Graphical Model (GGM) from real data. This procedure comes with a control of the false discovery rate. The method is described in the article "Enhancing the Power of Gaussian Graphical Model Inference by Modeling the Graph Structure" by Kilian, Rebafka, and Villers (2024) <arXiv:2402.19021>.